PubMed

Glucocorticoid receptor polymorphisms in major depression.

Spijker AT, van Rossum EF.

Ann N Y Acad Sci. 2009 Oct;1179:199-215.PMID: 19906241 [PubMed - in process]Related articles

Clinical features associated with glucocorticoid receptor polymorphisms.

Manenschijn L, van den Akker EL, Lamberts SW, van Rossum EF.

Ann N Y Acad Sci. 2009 Oct;1179:179-98.PMID: 19906240 [PubMed - in process]Related articles

A glucocorticoid receptor gene haplotype (TthIII1/ER22/23EK/9beta) is associated with a more aggressive disease course in multiple sclerosis.

van Winsen LM, Manenschijn L, van Rossum EF, Crusius JB, Koper JW, Polman CH, Uitdehaag BM.

J Clin Endocrinol Metab. 2009 Jun;94(6):2110-4. Epub 2009 Mar 24. Erratum in: J Clin Endocrinol Metab. 2009 Jul;94(7):2674. Crusius, Bart A [corrected to Crusius, J Bart A]. PMID: 19318444 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor gene variant is associated with increased body fatness in youngsters.

Voorhoeve PG, van den Akker EL, van Rossum EF, Koper JW, van Mechelen W, Lamberts SW, Delemarre-van de Waal HA.

Clin Endocrinol (Oxf). 2009 Oct;71(4):518-23. Epub 2009 Feb 16.PMID: 19222494 [PubMed - in process]Related articles

Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder.

Spijker AT, van Rossum EF, Hoencamp E, DeRijk RH, Haffmans J, Blom M, Manenschijn L, Koper JW, Lamberts SW, Zitman FG.

Bipolar Disord. 2009 Feb;11(1):95-101.PMID: 19133972 [PubMed - indexed for MEDLINE]Related articles

Two common haplotypes of the glucocorticoid receptor gene are associated with increased susceptibility to cardiovascular disease in men with familial hypercholesterolemia.

Koeijvoets KC, van der Net JB, van Rossum EF, Steyerberg EW, Defesche JC, Kastelein JJ, Lamberts SW, Sijbrands EJ.

J Clin Endocrinol Metab. 2008 Dec;93(12):4902-8. Epub 2008 Sep 23.PMID: 18812484 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor gene polymorphisms and glucocorticoid sensitivity of subdermal blood vessels and leukocytes.

Kumsta R, Entringer S, Koper JW, van Rossum EF, Hellhammer DH, Wüst S.

Biol Psychol. 2008 Oct;79(2):179-84. Epub 2008 Apr 16.PMID: 18502562 [PubMed - indexed for MEDLINE]Related articles

The relationship between cortisol, muscle mass and muscle strength in older persons and the role of genetic variations in the glucocorticoid receptor.

Peeters GM, van Schoor NM, van Rossum EF, Visser M, Lips P.

Clin Endocrinol (Oxf). 2008 Oct;69(4):673-82. Epub 2008 Jan 31.PMID: 18248637 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor gene and risk of cardiovascular disease.

van den Akker EL, Koper JW, van Rossum EF, Dekker MJ, Russcher H, de Jong FH, Uitterlinden AG, Hofman A, Pols HA, Witteman JC, Lamberts SW.

Arch Intern Med. 2008 Jan 14;168(1):33-9.PMID: 18195193 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress.

Kumsta R, Entringer S, Koper JW, van Rossum EF, Hellhammer DH, Wüst S.

Biol Psychiatry. 2007 Oct 15;62(8):863-9. Epub 2007 Aug 23.PMID: 17716631 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.

van Winsen LM, Hooper-van Veen T, van Rossum EF, Koper JW, Barkhof F, Polman CH, Uitdehaag BM.

J Neuroimmunol. 2007 May;186(1-2):150-5. Epub 2007 Mar 28.PMID: 17395275 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid receptor variant and risk of dementia and white matter lesions.

van Rossum EF, de Jong FJ, Koper JW, Uitterlinden AG, Prins ND, van Dijk EJ, Koudstaal PJ, Hofman A, de Jong FH, Lamberts SW, Breteler MM.

Neurobiol Aging. 2008 May;29(5):716-23. Epub 2006 Dec 20.PMID: 17184882 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid resistance syndrome: A diagnostic and therapeutic approach.

van Rossum EF, Lamberts SW.

Best Pract Res Clin Endocrinol Metab. 2006 Dec;20(4):611-26. Review.PMID: 17161335 [PubMed - indexed for MEDLINE]Related articles

Prediction of treatment response by HPA-axis and glucocorticoid receptor polymorphisms in major depression.

Brouwer JP, Appelhof BC, van Rossum EF, Koper JW, Fliers E, Huyser J, Schene AH, Tijssen JG, Van Dyck R, Lamberts SW, Wiersinga WM, Hoogendijk WJ.

Psychoneuroendocrinology. 2006 Nov;31(10):1154-63. Epub 2006 Oct 10.PMID: 17034955 [PubMed - indexed for MEDLINE]Related articles

Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms.

van den Akker EL, Nouwen JL, Melles DC, van Rossum EF, Koper JW, Uitterlinden AG, Hofman A, Verbrugh HA, Pols HA, Lamberts SW, van Belkum A.

J Infect Dis. 2006 Sep 15;194(6):814-8. Epub 2006 Aug 8.PMID: 16941349 [PubMed - indexed for MEDLINE]Related articles

A functional polymorphism in the glucocorticoid receptor gene and its relation to cardiovascular disease risk in familial hypercholesterolemia.

Koeijvoets KC, van Rossum EF, Dallinga-Thie GM, Steyerberg EW, Defesche JC, Kastelein JJ, Lamberts SW, Sijbrands EJ.

J Clin Endocrinol Metab. 2006 Oct;91(10):4131-6. Epub 2006 Jul 18.PMID: 16849409 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid receptor polymorphism affects transrepression but not transactivation.

van den Akker EL, Russcher H, van Rossum EF, Brinkmann AO, de Jong FH, Hokken A, Pols HA, Koper JW, Lamberts SW.

J Clin Endocrinol Metab. 2006 Jul;91(7):2800-3. Epub 2006 May 9.PMID: 16684836 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the glucocorticoid receptor gene and major depression.

van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F.

Biol Psychiatry. 2006 Apr 15;59(8):681-8.PMID: 16580345 [PubMed - indexed for MEDLINE]Related articles

Association between an IGF-I gene polymorphism and body fatness: differences between generations.

Voorhoeve PG, van Rossum EF, Te Velde SJ, Koper JW, Kemper HC, Lamberts SW, de Waal HA.

Eur J Endocrinol. 2006 Mar;154(3):379-88.PMID: 16498050 [PubMed - indexed for MEDLINE]Related articlesFree article

Strategies for the characterization of disorders in cortisol sensitivity.

Russcher H, Smit P, van Rossum EF, van den Akker EL, Brinkmann AO, de Heide LJ, de Jong FH, Koper JW, Lamberts SW.

J Clin Endocrinol Metab. 2006 Feb;91(2):694-701. Epub 2005 Nov 29.PMID: 16317053 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic polymorphisms and multifactorial diseases: facts and fallacies revealed by the glucocorticoid receptor gene.

van Rossum EF, Russcher H, Lamberts SW.

Trends Endocrinol Metab. 2005 Dec;16(10):445-50. Epub 2005 Nov 4. Review.PMID: 16275120 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia.

Tissing WJ, Meijerink JP, den Boer ML, Brinkhof B, van Rossum EF, van Wering ER, Koper JW, Sonneveld P, Pieters R.

Clin Cancer Res. 2005 Aug 15;11(16):6050-6.PMID: 16115950 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of glucocorticoid receptor gene polymorphisms on glucocorticoid sensitivity is outweighted in patients with multiple sclerosis.

van Winsen LL, Hooper-van Veen T, van Rossum EF, Polman CH, van den Berg TK, Koper JW, Uitdehaag BM.

J Neuroimmunol. 2005 Oct;167(1-2):150-6.PMID: 16083972 [PubMed - indexed for MEDLINE]Related articles

Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression.

Russcher H, Smit P, van den Akker EL, van Rossum EF, Brinkmann AO, de Jong FH, Lamberts SW, Koper JW.

J Clin Endocrinol Metab. 2005 Oct;90(10):5804-10. Epub 2005 Jul 19.PMID: 16030164 [PubMed - indexed for MEDLINE]Related articlesFree article

An IGF-I promoter polymorphism modifies the relationships between birth weight and risk factors for cardiovascular disease and diabetes at age 36.

te Velde SJ, van Rossum EF, Voorhoeve PG, Twisk JW, Delemarre van de Waal HA, Stehouwer CD, van Mechelen W, Lamberts SW, Kemper HC.

BMC Endocr Disord. 2005 Jun 1;5:5.PMID: 15927083 [PubMed]Related articlesFree article

Increased expression of the glucocorticoid receptor-A translational isoform as a result of the ER22/23EK polymorphism.

Russcher H, van Rossum EF, de Jong FH, Brinkmann AO, Lamberts SW, Koper JW.

Mol Endocrinol. 2005 Jul;19(7):1687-96. Epub 2005 Mar 3.PMID: 15746190 [PubMed - indexed for MEDLINE]Related articlesFree article

A psychobiological perspective on genetic determinants of hypothalamus-pituitary-adrenal axis activity.

Wüst S, Federenko IS, van Rossum EF, Koper JW, Kumsta R, Entringer S, Hellhammer DH.

Ann N Y Acad Sci. 2004 Dec;1032:52-62. Review.PMID: 15677395 [PubMed - indexed for MEDLINE]Related articles

Characterization of a promoter polymorphism in the glucocorticoid receptor gene and its relationship to three other polymorphisms.

van Rossum EF, Roks PH, de Jong FH, Brinkmann AO, Pols HA, Koper JW, Lamberts SW.

Clin Endocrinol (Oxf). 2004 Nov;61(5):573-81.PMID: 15521959 [PubMed - indexed for MEDLINE]Related articles

Habituation of cortisol responses to repeated psychosocial stress-further characterization and impact of genetic factors.

Wüst S, Federenko IS, van Rossum EF, Koper JW, Hellhammer DH.

Psychoneuroendocrinology. 2005 Feb;30(2):199-211.PMID: 15471617 [PubMed - indexed for MEDLINE]Related articles

The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a beneficial body composition and muscle strength in young adults.

van Rossum EF, Voorhoeve PG, te Velde SJ, Koper JW, Delemarre-van de Waal HA, Kemper HC, Lamberts SW.

J Clin Endocrinol Metab. 2004 Aug;89(8):4004-9.PMID: 15292341 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men.

van Rossum EF, Feelders RA, van den Beld AW, Uitterlinden AG, Janssen JA, Ester W, Brinkmann AO, Grobbee DE, de Jong FH, Pols HA, Koper JW, Lamberts SW.

Am J Med. 2004 Aug 1;117(3):158-62.PMID: 15276593 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study).

Bleumink GS, Rietveld I, Janssen JA, van Rossum EF, Deckers JW, Hofman A, Witteman JC, van Duijn CM, Stricker BH.

Am J Cardiol. 2004 Aug 1;94(3):384-6.PMID: 15276114 [PubMed - indexed for MEDLINE]Related articles

A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height.

Rietveld I, Janssen JA, van Rossum EF, Houwing-Duistermaat JJ, Rivadeneira F, Hofman A, Pols HA, van Duijn CM, Lamberts SW.

Clin Endocrinol (Oxf). 2004 Aug;61(2):195-203.PMID: 15272914 [PubMed - indexed for MEDLINE]Related articles

Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress.

Wüst S, Van Rossum EF, Federenko IS, Koper JW, Kumsta R, Hellhammer DH.

J Clin Endocrinol Metab. 2004 Feb;89(2):565-73.PMID: 14764763 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition.

van Rossum EF, Lamberts SW.

Recent Prog Horm Res. 2004;59:333-57. Review.PMID: 14749509 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index.

van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, Ester W, Janssen JA, Brinkmann AO, de Jong FH, Grobbee DE, Pols HA, Lamberts SW.

Clin Endocrinol (Oxf). 2003 Nov;59(5):585-92.PMID: 14616881 [PubMed - indexed for MEDLINE]Related articles

The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients.

Di Blasio AM, van Rossum EF, Maestrini S, Berselli ME, Tagliaferri M, Podestà F, Koper JW, Liuzzi A, Lamberts SW.

Clin Endocrinol (Oxf). 2003 Jul;59(1):68-74.PMID: 12807506 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels.

van Rossum EF, Koper JW, Huizenga NA, Uitterlinden AG, Janssen JA, Brinkmann AO, Grobbee DE, de Jong FH, van Duyn CM, Pols HA, Lamberts SW.

Diabetes. 2002 Oct;51(10):3128-34.PMID: 12351458 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain.

Nicklas BJ, van Rossum EF, Berman DM, Ryan AS, Dennis KE, Shuldiner AR.

Diabetes. 2001 Sep;50(9):2172-6.PMID: 11522688 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin responses to weight loss in postmenopausal women: relationship to sex-hormone binding globulin and visceral obesity.

van Rossum EF, Nicklas BJ, Dennis KE, Berman DM, Goldberg AP.

Obes Res. 2000 Jan;8(1):29-35.PMID: 10678256 [PubMed - indexed for MEDLINE]Related articles