PubMed

Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress.

Yang HH, van Breemen C, Chung AW.

Vascul Pharmacol. 2009 Oct 29. [Epub ahead of print]PMID: 19879959 [PubMed - as supplied by publisher]Related articles

Dysfunction of endothelial and smooth muscle cells in small arteries of a mouse model of Marfan syndrome.

Syyong HT, Chung AW, Yang HH, van Breemen C.

Br J Pharmacol. 2009 Nov;158(6):1597-608. Epub 2009 Oct 8.PMID: 19814726 [PubMed - in process]Related articles

Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome.

Yang HH, Kim JM, Chum E, van Breemen C, Chung AW.

Br J Pharmacol. 2009 Nov;158(6):1503-12. Epub 2009 Oct 8.PMID: 19814725 [PubMed - in process]Related articles

A model for the generation of localized transient [Na+] elevations in vascular smooth muscle.

Fameli N, Kuo KH, van Breemen C.

Biochem Biophys Res Commun. 2009 Nov 20;389(3):461-5. Epub 2009 Sep 3.PMID: 19733153 [PubMed - indexed for MEDLINE]Related articles

Diabetes modulates capacitative calcium entry and expression of transient receptor potential canonical channels in human saphenous vein.

Chung AW, Au Yeung K, Chum E, Okon EB, van Breemen C.

Eur J Pharmacol. 2009 Jun 24;613(1-3):114-8. Epub 2009 Apr 23.PMID: 19393642 [PubMed - indexed for MEDLINE]Related articles

Mechanism of asynchronous Ca(2+) waves underlying agonist-induced contraction in the rat basilar artery.

Syyong HT, Yang HH, Trinh G, Cheung C, Kuo KH, van Breemen C.

Br J Pharmacol. 2009 Feb;156(4):587-600. Epub 2009 Jan 16.PMID: 19154440 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial regulation of sarcoplasmic reticulum Ca2+ content in vascular smooth muscle cells.

Poburko D, Liao CH, van Breemen C, Demaurex N.

Circ Res. 2009 Jan 2;104(1):104-12. Epub 2008 Nov 20.PMID: 19023135 [PubMed - indexed for MEDLINE]Related articles

Ca2+ signaling in smooth muscle: TRPC6, NCX and LNats in nanodomains.

Poburko D, Fameli N, Kuo KH, van Breemen C.

Channels (Austin). 2008 Jan-Feb;2(1):10-2. Epub 2008 Apr 7.PMID: 18690050 [PubMed - indexed for MEDLINE]Related articles

P2Y2 receptor-mediated Ca2+ signaling and spontaneous Ca2+ releases in human valvular myofibroblasts.

Liang W, McDonald P, McManus B, van Breemen C, Wang X.

Int Heart J. 2008 Mar;49(2):221-36.PMID: 18475022 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

Chung AW, Yang HH, Radomski MW, van Breemen C.

Circ Res. 2008 Apr 25;102(8):e73-85. Epub 2008 Apr 3.PMID: 18388324 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased matrix metalloproteinase 2 activity in the human internal mammary artery is associated with ageing, hypertension, diabetes and kidney dysfunction.

Chung AW, Booth AD, Rose C, Thompson CR, Levin A, van Breemen C.

J Vasc Res. 2008;45(4):357-62. Epub 2008 Mar 10.PMID: 18332634 [PubMed - indexed for MEDLINE]Related articles

Mechanical and pharmacological approaches to investigate the pathogenesis of Marfan syndrome in the abdominal aorta.

Chung AW, Yang HH, Yeung KA, van Breemen C.

J Vasc Res. 2008;45(4):314-22. Epub 2008 Jan 22.PMID: 18212506 [PubMed - indexed for MEDLINE]Related articles

Characteristics of agonist-induced Ca2+ responses in diseased human valvular myofibroblasts.

Liang W, McDonald P, McManus B, van Breemen C, Wang X.

Proc West Pharmacol Soc. 2008;51:11-4.PMID: 19544665 [PubMed - indexed for MEDLINE]Related articles

Arterialization of a vein graft promotes cell cycle progression through Akt and p38 mitogen-activated protein kinase pathways: impact of the preparation procedure.

Chung AW, Wong J, Luo H, Hsiang YN, van Breemen C, Okon EB.

Can J Cardiol. 2007 Dec;23(14):1147-54.PMID: 18060101 [PubMed - indexed for MEDLINE]Related articlesFree article

Transient receptor potential channel 6-mediated, localized cytosolic [Na+] transients drive Na+/Ca2+ exchanger-mediated Ca2+ entry in purinergically stimulated aorta smooth muscle cells.

Poburko D, Liao CH, Lemos VS, Lin E, Maruyama Y, Cole WC, van Breemen C.

Circ Res. 2007 Nov 9;101(10):1030-8. Epub 2007 Sep 13.PMID: 17872462 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1-mediated wave-like [Ca2+]i oscillations in intact rabbit inferior vena cava.

Dai J, Lee CH, Poburko D, Szado T, Kuo KH, van Breemen C.

J Vasc Res. 2007;44(6):495-503. Epub 2007 Jul 27. Erratum in: J Vasc Res. 2007;44(6):503. PMID: 17657165 [PubMed - indexed for MEDLINE]Related articles

Imbalanced synthesis of cyclooxygenase-derived thromboxane A2 and prostacyclin compromises vasomotor function of the thoracic aorta in Marfan syndrome.

Chung AW, Yang HH, van Breemen C.

Br J Pharmacol. 2007 Oct;152(3):305-12. Epub 2007 Jul 16.PMID: 17641673 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.

Chung AW, Au Yeung K, Sandor GG, Judge DP, Dietz HC, van Breemen C.

Circ Res. 2007 Aug 31;101(5):512-22. Epub 2007 Jul 19.PMID: 17641224 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia and hyperlipidemia are associated with endothelial dysfunction during the development of type 2 diabetes.

Okon EB, Chung AW, Zhang H, Laher I, van Breemen C.

Can J Physiol Pharmacol. 2007 May;85(5):562-7.PMID: 17632592 [PubMed - indexed for MEDLINE]Related articles

ATP promotes NCX-reversal in aortic smooth muscle cells by DAG-activated Na+ entry.

Syyong HT, Poburko D, Fameli N, van Breemen C.

Biochem Biophys Res Commun. 2007 Jun 15;357(4):1177-82. Epub 2007 Apr 20.PMID: 17466270 [PubMed - indexed for MEDLINE]Related articles

A quantitative model for linking Na+/Ca2+ exchanger to SERCA during refilling of the sarcoplasmic reticulum to sustain [Ca2+] oscillations in vascular smooth muscle.

Fameli N, van Breemen C, Kuo KH.

Cell Calcium. 2007 Dec;42(6):565-75. Epub 2007 Apr 6.PMID: 17418403 [PubMed - indexed for MEDLINE]Related articles

Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.

Chung AW, Au Yeung K, Cortes SF, Sandor GG, Judge DP, Dietz HC, van Breemen C.

Br J Pharmacol. 2007 Apr;150(8):1075-83. Epub 2007 Mar 5.PMID: 17339838 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced cell cycle entry and mitogen-activated protein kinase-signaling and downregulation of matrix metalloproteinase-1 and -3 in human diabetic arterial vasculature.

Chung AW, Luo H, Tejerina T, van Breemen C, Okon EB.

Atherosclerosis. 2007 Nov;195(1):e1-8. Epub 2007 Feb 20.PMID: 17316652 [PubMed - indexed for MEDLINE]Related articles

Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.

Dai JM, Kuo KH, Leo JM, Paré PD, van Breemen C, Lee CH.

Am J Respir Cell Mol Biol. 2007 May;36(5):600-8. Epub 2006 Dec 14.PMID: 17170384 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+ entry via TRPC6 causes Ca2+ entry via NCX reversal in ATP stimulated smooth muscle cells.

Lemos VS, Poburko D, Liao CH, Cole WC, van Breemen C.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):130-4. Epub 2006 Nov 7.PMID: 17112478 [PubMed - indexed for MEDLINE]Related articles

Pharmacologic relaxation of vein grafts is beneficial compared with pressure distention caused by upregulation of endothelial nitric oxide synthase and nitric oxide production.

Chung AW, Rauniyar P, Luo H, Hsiang YN, van Breemen C, Okon EB.

J Thorac Cardiovasc Surg. 2006 Oct;132(4):925-32.PMID: 17000306 [PubMed - indexed for MEDLINE]Related articles

Mitochondria buffer NCX-mediated Ca2+-entry and limit its diffusion into vascular smooth muscle cells.

Poburko D, Potter K, van Breemen E, Fameli N, Liao CH, Basset O, Ruegg UT, van Breemen C.

Cell Calcium. 2006 Oct;40(4):359-71. Epub 2006 Jun 27.PMID: 16806462 [PubMed - indexed for MEDLINE]Related articles

Reduced expression of vascular endothelial growth factor paralleled with the increased angiostatin expression resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in human type 2 diabetic arterial vasculature.

Chung AW, Hsiang YN, Matzke LA, McManus BM, van Breemen C, Okon EB.

Circ Res. 2006 Jul 21;99(2):140-8. Epub 2006 Jun 15.PMID: 16778129 [PubMed - indexed for MEDLINE]Related articlesFree article

Human vascular smooth muscle cells from diabetic patients are resistant to induced apoptosis due to high Bcl-2 expression.

Ruiz E, Gordillo-Moscoso A, Padilla E, Redondo S, Rodriguez E, Reguillo F, Briones AM, van Breemen C, Okon E, Tejerina T.

Diabetes. 2006 May;55(5):1243-51.PMID: 16644678 [PubMed - indexed for MEDLINE]Related articlesFree article

TRP proteins: a new dimension in the treatment of occlusive vascular disease.

van Breemen C, Poburko D, Okon EB.

Circ Res. 2006 Mar 3;98(4):446-7. No abstract available. PMID: 16514075 [PubMed - indexed for MEDLINE]Related articlesFree article

Store-operated Ca2+ entry modulates sarcoplasmic reticulum Ca2+ loading in neonatal rabbit cardiac ventricular myocytes.

Huang J, van Breemen C, Kuo KH, Hove-Madsen L, Tibbits GF.

Am J Physiol Cell Physiol. 2006 Jun;290(6):C1572-82. Epub 2006 Jan 18.PMID: 16421209 [PubMed - indexed for MEDLINE]Related articlesFree article

Asynchronous calcium waves in smooth muscle cells.

Lee CH, Kuo KH, Dai J, van Breemen C.

Can J Physiol Pharmacol. 2005 Aug-Sep;83(8-9):733-41. Review.PMID: 16333375 [PubMed - indexed for MEDLINE]Related articles

Pressure distention compared with pharmacologic relaxation in vein grafting upregulates matrix metalloproteinase-2 and -9.

Chung AW, Rauniyar P, Luo H, Hsiang YN, van Breemen C, Okon EB.

J Vasc Surg. 2005 Oct;42(4):747-56.PMID: 16242564 [PubMed - indexed for MEDLINE]Related articles

Mechanism of ACh-induced asynchronous calcium waves and tonic contraction in porcine tracheal muscle bundle.

Dai JM, Kuo KH, Leo JM, van Breemen C, Lee CH.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L459-69. Epub 2005 Oct 7.PMID: 16214818 [PubMed - indexed for MEDLINE]Related articlesFree article

Compromised arterial function in human type 2 diabetic patients.

Okon EB, Chung AW, Rauniyar P, Padilla E, Tejerina T, McManus BM, Luo H, van Breemen C.

Diabetes. 2005 Aug;54(8):2415-23.PMID: 16046309 [PubMed - indexed for MEDLINE]Related articlesFree article

Rearrangement of the close contact between the mitochondria and the sarcoplasmic reticulum in airway smooth muscle.

Dai J, Kuo KH, Leo JM, van Breemen C, Lee CH.

Cell Calcium. 2005 Apr;37(4):333-40.PMID: 15755494 [PubMed - indexed for MEDLINE]Related articles

Basal calcium entry in vascular smooth muscle.

Poburko D, Lhote P, Szado T, Behra T, Rahimian R, McManus B, van Breemen C, Ruegg UT.

Eur J Pharmacol. 2004 Nov 28;505(1-3):19-29.PMID: 15556133 [PubMed - indexed for MEDLINE]Related articles

Vectorial Ca2+ release via ryanodine receptors contributes to Ca2+ extrusion from freshly isolated rabbit aortic endothelial cells.

Liang W, Buluc M, van Breemen C, Wang X.

Cell Calcium. 2004 Nov;36(5):431-43.PMID: 15451626 [PubMed - indexed for MEDLINE]Related articles

Estrogen modulation of endothelium-derived relaxing factors by human endothelial cells.

Rahimian R, Chan L, Goel A, Poburko D, van Breemen C.

Biochem Biophys Res Commun. 2004 Sep 17;322(2):373-9.PMID: 15325240 [PubMed - indexed for MEDLINE]Related articles

Involvement of inositol 1,4,5-trisphosphate in nicotinic calcium responses in dystrophic myotubes assessed by near-plasma membrane calcium measurement.

Basset O, Boittin FX, Dorchies OM, Chatton JY, van Breemen C, Ruegg UT.

J Biol Chem. 2004 Nov 5;279(45):47092-100. Epub 2004 Aug 18.PMID: 15322099 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular smooth muscle mitochondria at the cross roads of Ca(2+) regulation.

Poburko D, Lee CH, van Breemen C.

Cell Calcium. 2004 Jun;35(6):509-21. Review.PMID: 15110141 [PubMed - indexed for MEDLINE]Related articles

Novel regulatory mechanism of cardiomyocyte contractility involving ICAM-1 and the cytoskeleton.

Davani EY, Dorscheid DR, Lee CH, van Breemen C, Walley KR.

Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1013-22. Epub 2004 Apr 15.PMID: 15087287 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of calcium homeostasis in adenocarcinoma cell line A549 and its Taxol-resistant subclone.

Padar S, van Breemen C, Thomas DW, Uchizono JA, Livesey JC, Rahimian R.

Br J Pharmacol. 2004 May;142(2):305-16. Epub 2004 Apr 5.PMID: 15066902 [PubMed - indexed for MEDLINE]Related articlesFree article

Traction injury during minimally invasive harvesting of the saphenous vein is associated with impaired endothelial function.

Cook RC, Crowley CM, Hayden R, Gao M, Fedoruk L, Lichtenstein SV, van Breemen C.

J Thorac Cardiovasc Surg. 2004 Jan;127(1):65-71.PMID: 14752414 [PubMed - indexed for MEDLINE]Related articles

Effect of moderate pressure distention on the human saphenous vein vasomotor function.

Okon EB, Millar MJ, Crowley CM, Bashir JG, Cook RC, Hsiang YN, McManus B, van Breemen C.

Ann Thorac Surg. 2004 Jan;77(1):108-14; discussion 114-5.PMID: 14726044 [PubMed - indexed for MEDLINE]Related articles

Organellar junctions promote targeted Ca2+ signaling in smooth muscle: why two membranes are better than one.

Poburko D, Kuo KH, Dai J, Lee CH, van Breemen C.

Trends Pharmacol Sci. 2004 Jan;25(1):8-15. Review.PMID: 14723973 [PubMed - indexed for MEDLINE]Related articles

Novel Ca2+ signalling mechanisms in vascular myocytes: symposium overview.

Li PL, Lee HC, Nelson MT, Meininger GA, Van Breemen C.

Acta Physiol Scand. 2003 Dec;179(4):339-52.PMID: 14656371 [PubMed - indexed for MEDLINE]Related articles

Augmented contractile response of vascular smooth muscle in a diabetic mouse model.

Okon EB, Szado T, Laher I, McManus B, van Breemen C.

J Vasc Res. 2003 Nov-Dec;40(6):520-30. Epub 2003 Nov 27.PMID: 14646372 [PubMed - indexed for MEDLINE]Related articles

Relationship between asynchronous Ca2+ waves and force development in intact smooth muscle bundles of the porcine trachea.

Kuo KH, Dai J, Seow CY, Lee CH, van Breemen C.

Am J Physiol Lung Cell Mol Physiol. 2003 Dec;285(6):L1345-53. Epub 2003 Aug 22.PMID: 12936908 [PubMed - indexed for MEDLINE]Related articlesFree article

Histamine-induced Ca(2+) signaling in human valvular myofibroblasts.

Liang W, McDonald P, McManus B, van Breemen C, Wang X.

J Mol Cell Cardiol. 2003 Apr;35(4):379-88.PMID: 12689817 [PubMed - indexed for MEDLINE]Related articles