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    Results: 25

    1.

    ChREBP is a Negative Regulator of ARNT/HIF-1{beta} Gene Expression in Pancreatic Islet {beta}-Cells.

    Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I.

    Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833882 [PubMed - as supplied by publisher]Related articles

    2.

    Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

    Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

    Diabetes. 2009 Sep;58(9):2070-83. Epub 2009 Jun 19.PMID: 19542200 [PubMed - indexed for MEDLINE]Related articles

    3.

    TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.

    da Silva Xavier G, Loder MK, McDonald A, Tarasov AI, Carzaniga R, Kronenberger K, Barg S, Rutter GA.

    Diabetes. 2009 Apr;58(4):894-905. Epub 2009 Jan 23.PMID: 19168596 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells.

    Loder MK, da Silva Xavier G, McDonald A, Rutter GA.

    Biochem Soc Trans. 2008 Jun;36(Pt 3):357-9.PMID: 18481957 [PubMed - indexed for MEDLINE]Related articles

    5.

    ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile.

    Barrow SL, Voronina SG, da Silva Xavier G, Chvanov MA, Longbottom RE, Gerasimenko OV, Petersen OH, Rutter GA, Tepikin AV.

    Pflugers Arch. 2008 Mar;455(6):1025-39. Epub 2007 Oct 20.PMID: 17952455 [PubMed - indexed for MEDLINE]Related articles

    6.

    Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.

    Zatyka M, Ricketts C, da Silva Xavier G, Minton J, Fenton S, Hofmann-Thiel S, Rutter GA, Barrett TG.

    Hum Mol Genet. 2008 Jan 15;17(2):190-200. Epub 2007 Oct 18.PMID: 17947299 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

    Guillemain G, Filhoulaud G, Da Silva-Xavier G, Rutter GA, Scharfmann R.

    J Biol Chem. 2007 May 18;282(20):15228-37. Epub 2007 Mar 21.PMID: 17376780 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic beta-cells.

    An R, da Silva Xavier G, Hao HX, Semplici F, Rutter J, Rutter GA.

    Biochem Soc Trans. 2006 Nov;34(Pt 5):791-3.PMID: 17052199 [PubMed - indexed for MEDLINE]Related articles

    9.

    Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver.

    Rencurel F, Foretz M, Kaufmann MR, Stroka D, Looser R, Leclerc I, da Silva Xavier G, Rutter GA, Viollet B, Meyer UA.

    Mol Pharmacol. 2006 Dec;70(6):1925-34. Epub 2006 Sep 20.PMID: 16988011 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells.

    da Silva Xavier G, Rutter GA, Diraison F, Andreolas C, Leclerc I.

    J Lipid Res. 2006 Nov;47(11):2482-91. Epub 2006 Aug 4.PMID: 16891625 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

    Reimann F, Williams L, da Silva Xavier G, Rutter GA, Gribble FM.

    Diabetologia. 2004 Sep;47(9):1592-601. Epub 2004 Sep 9.PMID: 15365617 [PubMed - indexed for MEDLINE]Related articles

    12.

    Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose.

    da Silva Xavier G, Rutter J, Rutter GA.

    Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8319-24. Epub 2004 May 17.PMID: 15148392 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.

    Leclerc I, Woltersdorf WW, da Silva Xavier G, Rowe RL, Cross SE, Korbutt GS, Rajotte RV, Smith R, Rutter GA.

    Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1023-31. Epub 2004 Feb 10.PMID: 14871885 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6).

    Guillemain G, Da Silva Xavier G, Rafiq I, Leturque A, Rutter GA.

    Biochem J. 2004 Feb 15;378(Pt 1):219-27.PMID: 14632628 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing.

    Da Silva Xavier G, Qian Q, Cullen PJ, Rutter GA.

    Biochem J. 2004 Jan 1;377(Pt 1):149-58. Erratum in: Biochem J. 2004 Nov 1;383(Pt. 3):599. PMID: 14563207 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics.

    Tsuboi T, da Silva Xavier G, Leclerc I, Rutter GA.

    J Biol Chem. 2003 Dec 26;278(52):52042-51. Epub 2003 Oct 7.PMID: 14532293 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.

    Rutter GA, Da Silva Xavier G, Leclerc I.

    Biochem J. 2003 Oct 1;375(Pt 1):1-16. Review.PMID: 12839490 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression.

    da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, Rutter GA.

    Biochem J. 2003 May 1;371(Pt 3):761-74.PMID: 12589707 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.

    Tsuboi T, da Silva Xavier G, Holz GG, Jouaville LS, Thomas AP, Rutter GA.

    Biochem J. 2003 Jan 15;369(Pt 2):287-99.PMID: 12410638 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells.

    Andreolas C, da Silva Xavier G, Diraison F, Zhao C, Varadi A, Lopez-Casillas F, Ferré P, Foufelle F, Rutter GA.

    Diabetes. 2002 Aug;51(8):2536-45.PMID: 12145168 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

    Leclerc I, da Silva Xavier G, Rutter GA.

    Prog Nucleic Acid Res Mol Biol. 2002;71:69-90. Review.PMID: 12102561 [PubMed - indexed for MEDLINE]Related articles

    22.

    Role of AMP-activated protein kinase in the regulation of gene transcription.

    Leclerc I, Viollet B, da Silva Xavier G, Kahn A, Rutter GA.

    Biochem Soc Trans. 2002 Apr;30(2):307-11. Review.PMID: 12023870 [PubMed - indexed for MEDLINE]Related articles

    23.

    Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

    da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA.

    J Biol Chem. 2000 Nov 17;275(46):36269-77.PMID: 10967119 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2.

    Rafiq I, da Silva Xavier G, Hooper S, Rutter GA.

    J Biol Chem. 2000 May 26;275(21):15977-84.PMID: 10821851 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression.

    da Silva Xavier G, Leclerc I, Salt IP, Doiron B, Hardie DG, Kahn A, Rutter GA.

    Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4023-8.PMID: 10760274 [PubMed - indexed for MEDLINE]Related articlesFree article

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