PubMed

Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival.

Lee HY, Srinivas H, Xia D, Lu Y, Superty R, LaPushin R, Gomez-Manzano C, Gal AM, Walsh GL, Force T, Ueki K, Mills GB, Kurie JM.

J Biol Chem. 2003 Jun 27;278(26):23630-8. Epub 2003 Apr 24.PMID: 12714585 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways.

Kamiguti AS, Harris RJ, Slupsky JR, Baker PK, Cawley JC, Zuzel M.

Oncogene. 2003 Apr 17;22(15):2272-84.PMID: 12700663 [PubMed - indexed for MEDLINE]Related articles

Convergence of CpG DNA- and BCR-mediated signals at the c-Jun N-terminal kinase and NF-kappaB activation pathways: regulation by mitogen-activated protein kinases.

Yi AK, Yoon JG, Krieg AM.

Int Immunol. 2003 May;15(5):577-91.PMID: 12697659 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway.

Ohtsuka T, Buchsbaum D, Oliver P, Makhija S, Kimberly R, Zhou T.

Oncogene. 2003 Apr 3;22(13):2034-44.PMID: 12673208 [PubMed - indexed for MEDLINE]Related articles

Activation mechanism of c-Jun amino-terminal kinase in the course of endodermal differentiation of P19 embryonic carcinoma cells.

Kudo TA, Sakamoto Y, Tamura S, Kobayashi T.

FEBS Lett. 2003 Mar 27;539(1-3):29-33.PMID: 12650921 [PubMed - indexed for MEDLINE]Related articles

MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research.

Robinson VL, Hickson JA, Vander Griend DJ, Dubauskas Z, Rinker-Schaeffer CW.

Clin Exp Metastasis. 2003;20(1):25-30. Review.PMID: 12650604 [PubMed - indexed for MEDLINE]Related articles

Infrequent but high-level amplification of 17p11.2 approximately p12 in human glioma.

van Dartel M, Leenstra S, Troost D, Hulsebos TJ.

Cancer Genet Cytogenet. 2003 Jan 15;140(2):162-6.PMID: 12645656 [PubMed - indexed for MEDLINE]Related articles

A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation.

Poitras L, Bisson N, Islam N, Moss T.

Dev Biol. 2003 Feb 15;254(2):200-14.PMID: 12591241 [PubMed - indexed for MEDLINE]Related articles

The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.

Boldt S, Weidle UH, Kolch W.

Exp Cell Res. 2003 Feb 1;283(1):80-90.PMID: 12565821 [PubMed - indexed for MEDLINE]Related articles

Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon).

Li MG, Katsura K, Nomiyama H, Komaki K, Ninomiya-Tsuji J, Matsumoto K, Kobayashi T, Tamura S.

J Biol Chem. 2003 Apr 4;278(14):12013-21. Epub 2003 Jan 28.PMID: 12556533 [PubMed - indexed for MEDLINE]Related articlesFree article

Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways.

Witowsky JA, Johnson GL.

J Biol Chem. 2003 Jan 17;278(3):1403-6. Epub 2002 Nov 26.PMID: 12456688 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

Yamada SD, Hickson JA, Hrobowski Y, Vander Griend DJ, Benson D, Montag A, Karrison T, Huo D, Rutgers J, Adams S, Rinker-Schaeffer CW.

Cancer Res. 2002 Nov 15;62(22):6717-23.PMID: 12438272 [PubMed - indexed for MEDLINE]Related articlesFree article

The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor.

Reuther-Madrid JY, Kashatus D, Chen S, Li X, Westwick J, Davis RJ, Earp HS, Wang CY, Baldwin Jr AS Jr.

Mol Cell Biol. 2002 Dec;22(23):8175-83.PMID: 12417721 [PubMed - indexed for MEDLINE]Related articlesFree article

JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.

Lee CM, Onésime D, Reddy CD, Dhanasekaran N, Reddy EP.

Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14189-94. Epub 2002 Oct 21.PMID: 12391307 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and mutation analyses of MKK4, a candidate tumour suppressor gene encoded by chromosome 17p, in human gastric adenocarcinoma.

Chae KS, Ryu BK, Lee MG, Byun DS, Chi SG.

Eur J Cancer. 2002 Oct;38(15):2048-57.PMID: 12376211 [PubMed - indexed for MEDLINE]Related articles

Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer.

Lee HY, Suh YA, Lee JI, Hassan KA, Mao L, Force T, Gilbert BE, Jacks T, Kurie JM.

Clin Cancer Res. 2002 Sep;8(9):2970-5.PMID: 12231543 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H.

Antioxid Redox Signal. 2002 Jun;4(3):415-25. Review.PMID: 12215209 [PubMed - indexed for MEDLINE]Related articles

Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase.

Chen YR, Han J, Kori R, Kong AN, Tan TH.

J Biol Chem. 2002 Oct 18;277(42):39334-42. Epub 2002 Aug 8.PMID: 12171915 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical significance of AXL kinase family in gastric cancer.

Wu CW, Li AF, Chi CW, Lai CH, Huang CL, Lo SS, Lui WY, Lin WC.

Anticancer Res. 2002 Mar-Apr;22(2B):1071-8.PMID: 12168903 [PubMed - indexed for MEDLINE]Related articles

MEKK1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells.

Komoda F, Shino Y, Hirano T, Okutomi Y, Okamoto H, Hayashi Y, Suyama T, Ebara M, Saisho H, Shirasawa H.

Int J Oncol. 2002 Sep;21(3):553-9.PMID: 12168099 [PubMed - indexed for MEDLINE]Related articles