PubMed

Vascular endothelial growth factor and diabetic nephropathy.

Chen S, Ziyadeh FN.

Curr Diab Rep. 2008 Dec;8(6):470-6. Review.PMID: 18990304 [PubMed - indexed for MEDLINE]Related articles

Steroid treatment of drug-induced acute interstitial nephritis.

Karnib HH, Ziyadeh FN.

Kidney Int. 2008 Nov;74(10):1360; author reply 1360-1. No abstract available. PMID: 18974767 [PubMed - indexed for MEDLINE]Related articles

Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy.

Ziyadeh FN.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S38-41. Epub 2008 Oct 7. Review.PMID: 18842317 [PubMed - indexed for MEDLINE]Related articles

Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy.

Ziyadeh FN, Wolf G.

Curr Diabetes Rev. 2008 Feb;4(1):39-45. Review.PMID: 18220694 [PubMed - indexed for MEDLINE]Related articles

The utility of the transtubular potassium gradient in the evaluation of hyperkalemia.

Choi MJ, Ziyadeh FN.

J Am Soc Nephrol. 2008 Mar;19(3):424-6. Epub 2008 Jan 23.PMID: 18216310 [PubMed - indexed for MEDLINE]Related articlesFree article

Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.

Wang A, Ziyadeh FN, Lee EY, Pyagay PE, Sung SH, Sheardown SA, Laping NJ, Chen S.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1657-65. Epub 2007 Sep 5.PMID: 17804483 [PubMed - indexed for MEDLINE]Related articlesFree article

Taurine intestinal absorption and renal excretion test in diabetic patients: a pilot study.

Merheb M, Daher RT, Nasrallah M, Sabra R, Ziyadeh FN, Barada K.

Diabetes Care. 2007 Oct;30(10):2652-4. Epub 2007 Jul 31. No abstract available. PMID: 17666467 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular and molecular mechanisms of proteinuria in diabetic nephropathy.

Wolf G, Ziyadeh FN.

Nephron Physiol. 2007;106(2):p26-31. Epub 2007 Jun 6. Review.PMID: 17570945 [PubMed - indexed for MEDLINE]Related articles

Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice.

Sung SH, Ziyadeh FN, Wang A, Pyagay PE, Kanwar YS, Chen S.

J Am Soc Nephrol. 2006 Nov;17(11):3093-104. Epub 2006 Sep 20.PMID: 16988063 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin and renal fibrosis.

Wolf G, Ziyadeh FN.

Contrib Nephrol. 2006;151:175-83. Review.PMID: 16929141 [PubMed - indexed for MEDLINE]Related articles

Amadori-modified glycated serum proteins and accelerated atherosclerosis in diabetes: pathogenic and therapeutic implications.

Cohen MP, Ziyadeh FN, Chen S.

J Lab Clin Med. 2006 May;147(5):211-9. Review. No abstract available. PMID: 16697768 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test.

Ewens KG, George RA, Sharma K, Ziyadeh FN, Spielman RS.

Diabetes. 2005 Nov;54(11):3305-18.PMID: 16249459 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.

Cohen MP, Chen S, Ziyadeh FN, Shea E, Hud EA, Lautenslager GT, Shearman CW.

Kidney Int. 2005 Oct;68(4):1554-61.PMID: 16164632 [PubMed - indexed for MEDLINE]Related articles

From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy.

Wolf G, Chen S, Ziyadeh FN.

Diabetes. 2005 Jun;54(6):1626-34. Review.PMID: 15919782 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.

Chen S, Lee JS, Iglesias-de la Cruz MC, Wang A, Izquierdo-Lahuerta A, Gandhi NK, Danesh FR, Wolf G, Ziyadeh FN.

Nephrol Dial Transplant. 2005 Jul;20(7):1320-8. Epub 2005 Apr 19.PMID: 15840669 [PubMed - indexed for MEDLINE]Related articlesFree article

Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes.

Chen S, Kasama Y, Lee JS, Jim B, Marin M, Ziyadeh FN.

Diabetes. 2004 Nov;53(11):2939-49.PMID: 15504975 [PubMed - indexed for MEDLINE]Related articlesFree article

Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells.

Wolf G, Schroeder R, Ziyadeh FN, Stahl RA.

Kidney Int. 2004 Nov;66(5):1849-58.PMID: 15496155 [PubMed - indexed for MEDLINE]Related articles

Cultured tubule cells from TGF-beta1 null mice exhibit impaired hypertrophy and fibronectin expression in high glucose.

Chen S, Hoffman BB, Lee JS, Kasama Y, Jim B, Kopp JB, Ziyadeh FN.

Kidney Int. 2004 Apr;65(4):1191-204.PMID: 15086458 [PubMed - indexed for MEDLINE]Related articles

Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator.

Ziyadeh FN.

J Am Soc Nephrol. 2004 Jan;15 Suppl 1:S55-7. Review.PMID: 14684674 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-up.

Chen S, Jim B, Ziyadeh FN.

Semin Nephrol. 2003 Nov;23(6):532-43. Review.PMID: 14631561 [PubMed - indexed for MEDLINE]Related articles

Why should an angiogenic factor modulate tubular structure in diabetic nephropathy? Some answers, more questions.

Ziyadeh FN, Wolf G.

Kidney Int. 2003 Aug;64(2):758-9. Review. No abstract available. PMID: 12846777 [PubMed - indexed for MEDLINE]Related articles

Retinoids as a potential treatment for experimental puromycin-induced nephrosis.

Moreno-Manzano V, Mampaso F, Sepúlveda-Muñoz JC, Alique M, Chen S, Ziyadeh FN, Iglesias-de la Cruz MC, Rodríguez J, Nieto E, Orellana JM, Reyes P, Arribas I, Xu Q, Kitamura M, Lucio Cazana FJ.

Br J Pharmacol. 2003 Jun;139(4):823-31.PMID: 12813006 [PubMed - indexed for MEDLINE]Related articlesFree article

Overview: combating diabetic nephropathy.

Ziyadeh FN, Sharma K.

J Am Soc Nephrol. 2003 May;14(5):1355-7. Review. No abstract available. PMID: 12707405 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.

Chen S, Iglesias-de la Cruz MC, Jim B, Hong SW, Isono M, Ziyadeh FN.

Biochem Biophys Res Commun. 2003 Jan 3;300(1):16-22.PMID: 12480514 [PubMed - indexed for MEDLINE]Related articles

Regulation of inducible class II MHC, costimulatory molecules, and cytokine expression in TGF-beta1 knockout renal epithelial cells: effect of exogenous TGF-beta1.

Banu N, Mozes MM, Kopp JB, Ziyadeh FN, Meyers CM.

Exp Nephrol. 2002;10(5-6):320-31.PMID: 12381916 [PubMed - indexed for MEDLINE]Related articles

Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells.

Isono M, Chen S, Hong SW, Iglesias-de la Cruz MC, Ziyadeh FN.

Biochem Biophys Res Commun. 2002 Sep 6;296(5):1356-65.PMID: 12207925 [PubMed - indexed for MEDLINE]Related articles

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.

Iglesias-de la Cruz MC, Ziyadeh FN, Isono M, Kouahou M, Han DC, Kalluri R, Mundel P, Chen S.

Kidney Int. 2002 Sep;62(3):901-13.PMID: 12164872 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1.

Cohen MP, Ziyadeh FN, Hong SW, Shearman CW, Hud E, Lautenslager GT, Iglesias-de la Cruz MC, Chen S.

Kidney Int. 2002 Jun;61(6):2025-32.PMID: 12028443 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation.

Strutz F, Zeisberg M, Ziyadeh FN, Yang CQ, Kalluri R, Müller GA, Neilson EG.

Kidney Int. 2002 May;61(5):1714-28.PMID: 11967021 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin and renal disease.

Wolf G, Chen S, Han DC, Ziyadeh FN.

Am J Kidney Dis. 2002 Jan;39(1):1-11. Review.PMID: 11774095 [PubMed - indexed for MEDLINE]Related articles

The renin-angiotensin system in diabetic nephropathy.

Chen S, Wolf G, Ziyadeh FN.

Contrib Nephrol. 2001;(135):212-21. Review. No abstract available. PMID: 11705286 [PubMed - indexed for MEDLINE]Related articles

The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy.

Chen S, Hong SW, Iglesias-de la Cruz MC, Isono M, Casaretto A, Ziyadeh FN.

Ren Fail. 2001 May-Jul;23(3-4):471-81. Review.PMID: 11499562 [PubMed - indexed for MEDLINE]Related articles

TGF-beta: a crucial component of the pathogenesis of diabetic nephropathy.

Goldfarb S, Ziyadeh FN.

Trans Am Clin Climatol Assoc. 2001;112:27-32; discussion 33. Review.PMID: 11413780 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse.

Hong SW, Isono M, Chen S, Iglesias-De La Cruz MC, Han DC, Ziyadeh FN.

Am J Pathol. 2001 May;158(5):1653-63.PMID: 11337363 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-beta type II receptor expression.

Han DC, Isono M, Chen S, Casaretto A, Hong SW, Wolf G, Ziyadeh FN.

Kidney Int. 2001 Apr;59(4):1315-23.PMID: 11260392 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycated albumin stimulates TGF-beta 1 production and protein kinase C activity in glomerular endothelial cells.

Chen S, Cohen MP, Lautenslager GT, Shearman CW, Ziyadeh FN.

Kidney Int. 2001 Feb;59(2):673-81.PMID: 11168949 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cells.

Wolf G, Hannken T, Schroeder R, Zahner G, Ziyadeh FN, Stahl RA.

FEBS Lett. 2001 Jan 19;488(3):154-9.PMID: 11163763 [PubMed - indexed for MEDLINE]Related articles

Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells.

Iglesias-De La Cruz MC, Ruiz-Torres P, Alcamí J, Díez-Marqués L, Ortega-Velázquez R, Chen S, Rodríguez-Puyol M, Ziyadeh FN, Rodríguez-Puyol D.

Kidney Int. 2001 Jan;59(1):87-95.PMID: 11135061 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells.

Isono M, Cruz MC, Chen S, Hong SW, Ziyadeh FN.

J Am Soc Nephrol. 2000 Dec;11(12):2222-30.PMID: 11095645 [PubMed - indexed for MEDLINE]Related articlesFree article

F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes.

Montero A, Munger KA, Khan RZ, Valdivielso JM, Morrow JD, Guasch A, Ziyadeh FN, Badr KF.

Kidney Int. 2000 Nov;58(5):1963-72.PMID: 11044216 [PubMed - indexed for MEDLINE]Related articlesFree article

Utility of serum and urinary transforming growth factor-beta levels as markers of diabetic nephropathy.

Mogyorósi A, Kapoor A, Isono M, Kapoor S, Sharma K, Ziyadeh FN.

Nephron. 2000 Oct;86(2):234-5. No abstract available. PMID: 11015017 [PubMed - indexed for MEDLINE]Related articles

Amadori-glycated albumin in diabetic nephropathy: pathophysiologic connections.

Chen S, Cohen MP, Ziyadeh FN.

Kidney Int Suppl. 2000 Sep;77:S40-4. Review.PMID: 10997689 [PubMed - indexed for MEDLINE]Related articles

Diabetic kidney disease research: where do we stand at the turn of the century?

Lee HB, Ha H, Kim SI, Ziyadeh FN.

Kidney Int Suppl. 2000 Sep;77:S1-2. No abstract available. PMID: 10997683 [PubMed - indexed for MEDLINE]Related articles

Increased urinary transforming growth factor-beta(1) excretion in children with posterior urethral valves.

MacRae Dell K, Hoffman BB, Leonard MB, Ziyadeh FN, Schulman SL.

Urology. 2000 Aug 1;56(2):311-4.PMID: 10925100 [PubMed - indexed for MEDLINE]Related articles

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice.

Ziyadeh FN, Hoffman BB, Han DC, Iglesias-De La Cruz MC, Hong SW, Isono M, Chen S, McGowan TA, Sharma K.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8015-20.PMID: 10859350 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of TGF-beta type II receptor by high glucose in mouse mesangial cells and in diabetic kidney.

Isono M, Mogyorósi A, Han DC, Hoffman BB, Ziyadeh FN.

Am J Physiol Renal Physiol. 2000 May;278(5):F830-8.PMID: 10807596 [PubMed - indexed for MEDLINE]Related articlesFree article

The urine/plasma electrolyte ratio: a predictive guide to water restriction.

Furst H, Hallows KR, Post J, Chen S, Kotzker W, Goldfarb S, Ziyadeh FN, Neilson EG.

Am J Med Sci. 2000 Apr;319(4):240-4. Review.PMID: 10768609 [PubMed - indexed for MEDLINE]Related articles

Therapy with antisense TGF-beta1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice.

Han DC, Hoffman BB, Hong SW, Guo J, Ziyadeh FN.

Am J Physiol Renal Physiol. 2000 Apr;278(4):F628-34.PMID: 10751224 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte growth factor: a regulator of extracellular matrix genes in mouse mesangial cells.

Laping NJ, Olson BA, Ho T, Ziyadeh FN, Albrightson CR.

Biochem Pharmacol. 2000 Apr 1;59(7):847-53.PMID: 10718343 [PubMed - indexed for MEDLINE]Related articles

Angiotensin converting-enzyme inhibitor treatment reduces glomerular p16INK4 and p27Kip1 expression in diabetic BBdp rats.

Wolf G, Wenzel U, Ziyadeh FN, Stahl RA.

Diabetologia. 1999 Dec;42(12):1425-32.PMID: 10651261 [PubMed - indexed for MEDLINE]Related articles