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Sleep and Biomarkers of Atherosclerosis in Elderly Alzheimer Caregivers and Controls.

von Känel R, Ancoli-Israel S, Dimsdale JE, Mills PJ, Mausbach BT, Ziegler MG, Patterson TL, Grant I.

Gerontology. 2009 Dec 3. [Epub ahead of print]PMID: 19955705 [PubMed - as supplied by publisher]Related articles

Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal disease.

Friese RS, Rao F, Khandrika S, Thomas B, Ziegler MG, Schmid-Schönbein GW, O'Connor DT.

Clin Exp Hypertens. 2009 Oct;31(7):521-33.PMID: 19886850 [PubMed - in process]Related articles

Sleep and health-related quality of life in heart failure.

Mills PJ, Dimsdale JE, Natarajan L, Ziegler MG, Maisel A, Greenberg BH.

Congest Heart Fail. 2009 Sep-Oct;15(5):228-33.PMID: 19751424 [PubMed - in process]Related articles

Dopamine D1 receptor (DRD1) genetic polymorphism: pleiotropic effects on heritable renal traits.

Fung MM, Rana BK, Tang CM, Shiina T, Nievergelt CM, Rao F, Salem RM, Waalen J, Ziegler MG, Insel PA, O'Connor DT.

Kidney Int. 2009 Nov;76(10):1070-80. Epub 2009 Aug 12.PMID: 19675531 [PubMed - in process]Related articles

Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs.

Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, Schork NJ, O'Connor DT, Taylor P.

J Pharmacol Exp Ther. 2009 Nov;331(2):419-28. Epub 2009 Aug 11.PMID: 19671882 [PubMed - in process]Related articles

Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis.

Chen Y, Mahata M, Rao F, Khandrika S, Courel M, Fung MM, Zhang K, Stridsberg M, Ziegler MG, Hamilton BA, Lipkowitz MS, Taupenot L, Nievergelt C, Mahata SK, O'Connor DT.

J Am Soc Nephrol. 2009 Jul;20(7):1623-32. Epub 2009 Jun 11.PMID: 19520754 [PubMed - indexed for MEDLINE]Related articles

Influence of education and neighborhood poverty on pressor responses to phenylephrine in African-Americans and Caucasian-Americans.

Thomas KS, Nelesen RA, Ziegler MG, Natarajan L, Dimsdale JE.

Biol Psychol. 2009 Sep;82(1):18-24. Epub 2009 May 7.PMID: 19427353 [PubMed - indexed for MEDLINE]Related articles

The effects of ethnic discrimination and socioeconomic status on endothelin-1 among blacks and whites.

Cooper DC, Mills PJ, Bardwell WA, Ziegler MG, Dimsdale JE.

Am J Hypertens. 2009 Jul;22(7):698-704. Epub 2009 Apr 23.PMID: 19390511 [PubMed - indexed for MEDLINE]Related articles

A comparison of pharmacologic and spontaneous baroreflex methods in aging and hypertension.

Milic M, Sun P, Liu F, Fainman C, Dimsdale J, Mills PJ, Ziegler MG.

J Hypertens. 2009 Jun;27(6):1243-51.PMID: 19365284 [PubMed - indexed for MEDLINE]Related articles

Racial differences in the impact of social support on nocturnal blood pressure.

Cooper DC, Ziegler MG, Nelesen RA, Dimsdale JE.

Psychosom Med. 2009 Jun;71(5):524-31. Epub 2009 Mar 25.PMID: 19321852 [PubMed - indexed for MEDLINE]Related articles

Prolonged platelet activation in individuals with elevated blood pressure in response to a moderate exercise challenge.

Hong S, Adler KA, Von Känel R, Nordberg J, Ziegler MG, Mills PJ.

Psychophysiology. 2009 Mar;46(2):276-84. Epub 2009 Jan 26.PMID: 19170949 [PubMed - indexed for MEDLINE]Related articlesFree article

The roles of TNF-alpha and the soluble TNF receptor I on sleep architecture in OSA.

Yue HJ, Mills PJ, Ancoli-Israel S, Loredo JS, Ziegler MG, Dimsdale JE.

Sleep Breath. 2009 Aug;13(3):263-9. Epub 2009 Jan 16.PMID: 19148690 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent versus transient depressive symptoms in relation to platelet hyperactivation: a longitudinal analysis of dementia caregivers.

Aschbacher K, Roepke SK, von Känel R, Mills PJ, Mausbach BT, Patterson TL, Dimsdale JE, Ziegler MG, Ancoli-Israel S, Grant I.

J Affect Disord. 2009 Jul;116(1-2):80-7. Epub 2009 Jan 8.PMID: 19131112 [PubMed - indexed for MEDLINE]Related articles

Epinephrine regulation of hemodynamics in catecholamine knockouts and the pithed mouse.

Sun P, Bao X, Elayan H, Milic M, Liu F, Ziegler MG.

Ann N Y Acad Sci. 2008 Dec;1148:325-30.PMID: 19120125 [PubMed - indexed for MEDLINE]Related articles

Impaired chronotropic response to exercise in mice lacking catecholamines in adrenergic cells.

Bao X, Liu F, Gu Y, Lu CM, Ziegler MG.

Ann N Y Acad Sci. 2008 Dec;1148:297-301.PMID: 19120121 [PubMed - indexed for MEDLINE]Related articles

Adrenergic polymorphism and the human stress response.

Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, Ziegler MG, O'Connor DT.

Ann N Y Acad Sci. 2008 Dec;1148:282-96.PMID: 19120120 [PubMed - indexed for MEDLINE]Related articlesFree article

Depressive symptoms are associated with soluble P-selectin reactivity to acute exercise in heart failure.

Wirtz PH, Hong S, Redwine LS, Tafur J, Rutledge T, Ziegler MG, Greenberg B, Mills PJ.

Biol Psychiatry. 2009 May 1;65(9):801-7. Epub 2008 Dec 31.PMID: 19118820 [PubMed - indexed for MEDLINE]Related articles

Longitudinal platelet reactivity to acute psychological stress among older men and women.

Aschbacher K, von Känel R, Mills PJ, Roepke SK, Hong S, Dimsdale JE, Mausbach BT, Patterson TL, Ziegler MG, Ancoli-Israel S, Grant I.

Stress. 2009;12(5):426-33.PMID: 19096987 [PubMed - in process]Related articles

Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.

Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT.

J Am Coll Cardiol. 2008 Oct 28;52(18):1468-81.PMID: 19017515 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of gender and dementia severity on Alzheimer's disease caregivers' sleep and biomarkers of coagulation and inflammation.

Mills PJ, Ancoli-Israel S, von Känel R, Mausbach BT, Aschbacher K, Patterson TL, Ziegler MG, Dimsdale JE, Grant I.

Brain Behav Immun. 2009 Jul;23(5):605-10. Epub 2008 Oct 4.PMID: 18930805 [PubMed - indexed for MEDLINE]Related articles

The relationship between heart rate variability and inflammatory markers in cardiovascular diseases.

Haensel A, Mills PJ, Nelesen RA, Ziegler MG, Dimsdale JE.

Psychoneuroendocrinology. 2008 Nov;33(10):1305-12. Epub 2008 Sep 25. Review.PMID: 18819754 [PubMed - indexed for MEDLINE]Related articles

A 5-year longitudinal study of the relationships between stress, coping, and immune cell beta(2)-adrenergic receptor sensitivity.

Mausbach BT, Aschbacher K, Mills PJ, Roepke SK, von Känel R, Patterson TL, Dimsdale JE, Ziegler MG, Ancoli-Israel S, Grant I.

Psychiatry Res. 2008 Sep 30;160(3):247-55. Epub 2008 Aug 16.PMID: 18708265 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability and genome-wide linkage in US and australian twins identify novel genomic regions controlling chromogranin a: implications for secretion and blood pressure.

O'Connor DT, Zhu G, Rao F, Taupenot L, Fung MM, Das M, Mahata SK, Mahata M, Wang L, Zhang K, Greenwood TA, Shih PA, Cockburn MG, Ziegler MG, Stridsberg M, Martin NG, Whitfield JB.

Circulation. 2008 Jul 15;118(3):247-57. Epub 2008 Jun 30.PMID: 18591442 [PubMed - indexed for MEDLINE]Related articlesFree article

Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure.

Chen Y, Rao F, Rodriguez-Flores JL, Mahapatra NR, Mahata M, Wen G, Salem RM, Shih PA, Das M, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, O'Connor DT.

Kidney Int. 2008 Jul;74(1):115-25. Epub 2008 Apr 23. Erratum in: Kidney Int. 2009 Jun;75(11):1237. PMID: 18432188 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular responses to electrical stimulation of sympathetic nerves in the pithed mouse.

Elayan HH, Sun P, Milic M, Liu F, Bao X, Ziegler MG.

Auton Neurosci. 2008 Jun;140(1-2):49-52. Epub 2008 Apr 14.PMID: 18407806 [PubMed - indexed for MEDLINE]Related articlesFree article

Personal mastery is associated with reduced sympathetic arousal in stressed Alzheimer caregivers.

Roepke SK, Mausbach BT, Aschbacher K, Ziegler MG, Dimsdale JE, Mills PJ, von Känel R, Ancoli-Israel S, Patterson TL, Grant I.

Am J Geriatr Psychiatry. 2008 Apr;16(4):310-7.PMID: 18378556 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased Framingham Coronary Heart Disease Risk Score in dementia caregivers relative to non-caregiving controls.

von Känel R, Mausbach BT, Patterson TL, Dimsdale JE, Aschbacher K, Mills PJ, Ziegler MG, Ancoli-Israel S, Grant I.

Gerontology. 2008;54(3):131-7. Epub 2008 Jan 17.PMID: 18204247 [PubMed - indexed for MEDLINE]Related articles

Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans.

Fung MM, Nguyen C, Mehtani P, Salem RM, Perez B, Thomas B, Das M, Schork NJ, Mahata SK, Ziegler MG, O'Connor DT.

Circulation. 2008 Jan 29;117(4):517-25. Epub 2008 Jan 7.PMID: 18180394 [PubMed - indexed for MEDLINE]Related articlesFree article

The treatment of hypertension in the elderly.

Moser M, Cushman WC, Ziegler MG.

J Clin Hypertens (Greenwich). 2008 Jan;10(1):58-68.PMID: 18174772 [PubMed - indexed for MEDLINE]Related articles

Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers.

Aschbacher K, Mills PJ, von Känel R, Hong S, Mausbach BT, Roepke SK, Dimsdale JE, Patterson TL, Ziegler MG, Ancoli-Israel S, Grant I.

Brain Behav Immun. 2008 May;22(4):493-502. Epub 2007 Nov 28.PMID: 18054198 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination of caregiving stress and hormone replacement therapy is associated with prolonged platelet activation to acute stress among postmenopausal women.

Aschbacher K, von Känel R, Mills PJ, Hong S, Roepke SK, Mausbach BT, Patterson TL, Ziegler MG, Dimsdale JE, Ancoli-Israel S, Grant I.

Psychosom Med. 2007 Dec;69(9):910-7. Epub 2007 Nov 8.PMID: 17991824 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between heart rate variability, interleukin-6, and soluble tissue factor in healthy subjects.

von Känel R, Nelesen RA, Mills PJ, Ziegler MG, Dimsdale JE.

Brain Behav Immun. 2008 May;22(4):461-8. Epub 2007 Oct 30.PMID: 17977694 [PubMed - indexed for MEDLINE]Related articlesFree article

Spousal caregivers of patients with Alzheimer's disease show longitudinal increases in plasma level of tissue-type plasminogen activator antigen.

Mausbach BT, von Känel R, Aschbacher K, Roepke SK, Dimsdale JE, Ziegler MG, Mills PJ, Patterson TL, Ancoli-Israel S, Grant I.

Psychosom Med. 2007 Nov;69(8):816-22. Epub 2007 Oct 17.PMID: 17942832 [PubMed - indexed for MEDLINE]Related articlesFree article

Biogenesis of the secretory granule: chromogranin A coiled-coil structure results in unusual physical properties and suggests a mechanism for granule core condensation.

Mosley CA, Taupenot L, Biswas N, Taulane JP, Olson NH, Vaingankar SM, Wen G, Schork NJ, Ziegler MG, Mahata SK, O'Connor DT.

Biochemistry. 2007 Sep 25;46(38):10999-1012. Epub 2007 Aug 24.PMID: 17718510 [PubMed - indexed for MEDLINE]Related articles

Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk.

Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork NJ, Ziegler MG, O'Connor DT.

J Clin Invest. 2007 Sep;117(9):2658-71.PMID: 17717598 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo.

Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, Ziegler MG, O'Connor DT.

Circulation. 2007 Aug 28;116(9):993-1006. Epub 2007 Aug 13.PMID: 17698732 [PubMed - indexed for MEDLINE]Related articlesFree article

Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse.

Bao X, Lu CM, Liu F, Gu Y, Dalton ND, Zhu BQ, Foster E, Chen J, Karliner JS, Ross J Jr, Simpson PC, Ziegler MG.

Circulation. 2007 Aug 28;116(9):1024-31. Epub 2007 Aug 13.PMID: 17698731 [PubMed - indexed for MEDLINE]Related articlesFree article

The potential anti-inflammatory benefits of improving physical fitness in hypertension.

Edwards KM, Ziegler MG, Mills PJ.

J Hypertens. 2007 Aug;25(8):1533-42. Review.PMID: 17620945 [PubMed - indexed for MEDLINE]Related articles

Mood states, sympathetic activity, and in vivo beta-adrenergic receptor function in a normal population.

Yu BH, Kang EH, Ziegler MG, Mills PJ, Dimsdale JE.

Depress Anxiety. 2008;25(7):559-64.PMID: 17583588 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammation and sleep in healthy individuals.

Mills PJ, von Känel R, Norman D, Natarajan L, Ziegler MG, Dimsdale JE.

Sleep. 2007 Jun 1;30(6):729-35.PMID: 17580594 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation of autonomic activity to plasminogen activator inhibitor-1 plasma concentration and the role of body mass index.

von Känel R, Nelesen RA, Ziegler MG, Mausbach BT, Mills PJ, Dimsdale JE.

Blood Coagul Fibrinolysis. 2007 Jun;18(4):353-9.PMID: 17473577 [PubMed - indexed for MEDLINE]Related articles

Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.

Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork NJ, Hamilton BA, Ziegler MG, Mahata SK, O'Connor DT.

Circulation. 2007 May 1;115(17):2271-81. Epub 2007 Apr 16.PMID: 17438154 [PubMed - indexed for MEDLINE]Related articlesFree article

Heredity of endothelin secretion: human twin studies reveal the influence of polymorphism at the chromogranin A locus, a novel determinant of endothelial function.

Lillie EO, Mahata M, Khandrika S, Rao F, Bundey RA, Wen G, Chen Y, Taupenot L, Smith DW, Mahata SK, Ziegler MG, Cockburn M, Schork NJ, O'Connor DT.

Circulation. 2007 May 1;115(17):2282-91. Epub 2007 Apr 16.PMID: 17438153 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism.

Rao F, Wessel J, Wen G, Zhang L, Rana BK, Kennedy BP, Greenwood TA, Salem RM, Chen Y, Khandrika S, Hamilton BA, Smith DW, Holstein-Rathlou NH, Ziegler MG, Schork NJ, O'Connor DT.

Hypertension. 2007 May;49(5):1015-31. Epub 2007 Mar 12.PMID: 17353515 [PubMed - indexed for MEDLINE]Related articlesFree article

Sleepiness in obstructive sleep apnea: a harbinger of impaired cardiac function?

Choi JB, Nelesen R, Loredo JS, Mills PJ, Ancoli-Israel S, Ziegler MG, Dimsdale JE.

Sleep. 2006 Dec 1;29(12):1531-6.PMID: 17252883 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci.

Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, Ziegler MG, Witztum JL, Schork NJ, Schmid-Schönbein GW, O'Connor DT.

J Hypertens. 2007 Feb;25(2):329-43.PMID: 17211240 [PubMed - indexed for MEDLINE]Related articles

Population-based sample reveals gene-gender interactions in blood pressure in White Americans.

Rana BK, Insel PA, Payne SH, Abel K, Beutler E, Ziegler MG, Schork NJ, O'Connor DT.

Hypertension. 2007 Jan;49(1):96-106. Epub 2006 Dec 11.PMID: 17159089 [PubMed - indexed for MEDLINE]Related articlesFree article

Sleep disturbance, norepinephrine, and D-dimer are all related in elderly caregivers of people with Alzheimer disease.

Mausbach BT, Ancoli-Israel S, von Känel R, Patterson TL, Aschbacher K, Mills PJ, Ziegler MG, Dimsdale JE, Calleran S, Grant I.

Sleep. 2006 Oct 1;29(10):1347-52.PMID: 17068989 [PubMed - indexed for MEDLINE]Related articles

Ethnicity, perceived discrimination, and vascular reactivity to phenylephrine.

Thomas KS, Nelesen RA, Malcarne VL, Ziegler MG, Dimsdale JE.

Psychosom Med. 2006 Sep-Oct;68(5):692-7.PMID: 17012522 [PubMed - indexed for MEDLINE]Related articlesFree article

Does obstructive sleep apnea increase hematocrit?

Choi JB, Loredo JS, Norman D, Mills PJ, Ancoli-Israel S, Ziegler MG, Dimsdale JE.

Sleep Breath. 2006 Sep;10(3):155-60.PMID: 16770648 [PubMed - indexed for MEDLINE]Related articles