PubMed

Diet-induced obesity obstructs insulin signaling in the heart.

Young LH.

Am J Physiol Heart Circ Physiol. 2009 Nov 25. [Epub ahead of print]PMID: 19940075 [PubMed - as supplied by publisher]

Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion.

Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young LH.

J Clin Invest. 2009 Nov 16. pii: 39738. doi: 10.1172/JCI39738. [Epub ahead of print]PMID: 19920350 [PubMed - as supplied by publisher]Related articlesFree article

Lessons learned from the detection of ischemia in asymptomatic diabetics (DIAD) study.

Wackers FJ, Young LH.

J Nucl Cardiol. 2009 Nov-Dec;16(6):855-9. Epub 2009 Aug 15. No abstract available. PMID: 19685266 [PubMed - in process]Related articles

A crystallized view of AMPK activation.

Young LH.

Cell Metab. 2009 Jul;10(1):5-6.PMID: 19583947 [PubMed - indexed for MEDLINE]Related articles

International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia.

Faughnan ME, Palda VA, Garcia-Tsao G, Geisthoff UW, McDonald J, Proctor DD, Spears J, Brown DH, Buscarini E, Chesnutt MS, Cottin V, Ganguly A, Gossage JR, Guttmacher AE, Hyland RH, Kennedy SJ, Korzenik J, Mager JJ, Ozanne AP, Piccirillo JF, Picus D, Plauchu H, Porteous ME, Pyeritz RE, Ross DA, Sabba C, Swanson K, Terry P, Wallace MC, Westermann CJ, White RI, Young LH, Zarrabeitia R.

J Med Genet. 2009 Jun 29. [Epub ahead of print]PMID: 19553198 [PubMed - as supplied by publisher]Related articlesFree article

The pulmonary vascular complications of hereditary haemorrhagic telangiectasia.

Faughnan ME, Granton JT, Young LH.

Eur Respir J. 2009 May;33(5):1186-94. Review.PMID: 19407052 [PubMed - indexed for MEDLINE]Related articles

Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial.

Young LH, Wackers FJ, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Heller GV, Iskandrian AE, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE; DIAD Investigators.

JAMA. 2009 Apr 15;301(15):1547-55.PMID: 19366774 [PubMed - indexed for MEDLINE]Related articlesFree article

Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs).

Kernan WN, Viscoli CM, Demarco D, Mendes B, Shrauger K, Schindler JL, McVeety JC, Sicklick A, Moalli D, Greco P, Bravata DM, Eisen S, Resor L, Sena K, Story D, Brass LM, Furie KL, Gutmann L, Hinnau E, Gorman M, Lovejoy AM, Inzucchi SE, Young LH, Horwitz RI; IRIS Trial Investigators.

Neurology. 2009 Apr 14;72(15):1345-51.PMID: 19365056 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase: a core signalling pathway in the heart.

Kim AS, Miller EJ, Young LH.

Acta Physiol (Oxf). 2009 May;196(1):37-53. Epub 2009 Feb 23.PMID: 19239414 [PubMed - in process]Related articles

Spectral domain optical coherence tomography for quantitative evaluation of drusen and associated structural changes in non-neovascular age-related macular degeneration.

Yi K, Mujat M, Park BH, Sun W, Miller JW, Seddon JM, Young LH, de Boer JF, Chen TC.

Br J Ophthalmol. 2009 Feb;93(2):176-81. Epub 2008 Aug 12.PMID: 18697811 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms related to the cardioprotective effects of protein kinase C epsilon (PKC epsilon) peptide activator or inhibitor in rat ischemia/reperfusion injury.

Teng JC, Kay H, Chen Q, Adams JS, Grilli C, Guglielmello G, Zambrano C, Krass S, Bell A, Young LH.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Jul;378(1):1-15. Epub 2008 May 22.PMID: 18496674 [PubMed - indexed for MEDLINE]Related articles

Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome.

Drexler AJ, Nesto RW, Abrahamson MJ, Bakris G, Bell D, Brunzell J, Dandona P, Davidson J, Fonseca V, Fowler M, Frye R, Giles T, Haffner S, Hollenberg N, Hsueh W, Law R, Plutzky J, Ratner R, Reusch J, Selwyn A, Sowers J, Wyne K, Young LH.

Metab Syndr Relat Disord. 2005 Summer;3(2):147-73.PMID: 18370723 [PubMed - in process]Related articles

AMP-activated protein kinase conducts the ischemic stress response orchestra.

Young LH.

Circulation. 2008 Feb 12;117(6):832-40. Review. No abstract available. PMID: 18268160 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH.

Nature. 2008 Jan 31;451(7178):578-82.PMID: 18235500 [PubMed - indexed for MEDLINE]Related articles

Genetics of hereditary vitreoretinal degenerations.

Pachydaki SI, Young LH.

Semin Ophthalmol. 2007 Oct-Dec;22(4):219-27. Review.PMID: 18097985 [PubMed - indexed for MEDLINE]Related articles

Screening for coronary artery disease in patients with diabetes.

Bax JJ, Young LH, Frye RL, Bonow RO, Steinberg HO, Barrett EJ; ADA.

Diabetes Care. 2007 Oct;30(10):2729-36.PMID: 17901530 [PubMed - indexed for MEDLINE]Related articlesFree article

Resolution of asymptomatic myocardial ischemia in patients with type 2 diabetes in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study.

Wackers FJ, Chyun DA, Young LH, Heller GV, Iskandrian AE, Davey JA, Barrett EJ, Taillefer R, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE; Detection of Ischemia in Asymptomatic Diabetics (DIAD) Investigators.

Diabetes Care. 2007 Nov;30(11):2892-8. Epub 2007 Aug 6.PMID: 17682123 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraocular foreign body related endophthalmitis.

Waheed NK, Young LH.

Int Ophthalmol Clin. 2007 Spring;47(2):165-71. Review. No abstract available. PMID: 17450016 [PubMed - indexed for MEDLINE]Related articles

Acute retinal necrosis: an overview.

Chang S, Young LH.

Int Ophthalmol Clin. 2007 Spring;47(2):145-54. Review. No abstract available. PMID: 17450014 [PubMed - indexed for MEDLINE]Related articles

Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart.

Miller EJ, Li J, Sinusas KM, Holman GD, Young LH.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1922-8. Epub 2007 Mar 6.PMID: 17341550 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis.

Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI.

Cell Metab. 2007 Feb;5(2):151-6.PMID: 17276357 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

Zhang L, Li J, Young LH, Caplan MJ.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17272-7. Epub 2006 Nov 6.PMID: 17088526 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes mellitus and cardiovascular disease.

Chyun DA, Young LH.

Nurs Clin North Am. 2006 Dec;41(4):681-95, viii-ix. Review.PMID: 17059982 [PubMed - indexed for MEDLINE]Related articles

Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture.

Ament CS, Zacks DN, Lane AM, Krzystolik M, D'Amico DJ, Mukai S, Young LH, Loewenstein J, Arroyo J, Miller JW.

Arch Ophthalmol. 2006 Jul;124(7):957-66.PMID: 16832018 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal toxicity of intravitreal triamcinolone acetonide: a morphological study.

Yu SY, Damico FM, Viola F, D'Amico DJ, Young LH.

Retina. 2006 May-Jun;26(5):531-6.PMID: 16770259 [PubMed - indexed for MEDLINE]Related articles

Diagnostic tests for posterior segment inflammation.

Singh RP, Young LH.

Int Ophthalmol Clin. 2006 Spring;46(2):195-208. Review. No abstract available. PMID: 16770163 [PubMed - indexed for MEDLINE]Related articles

Management of ocular toxoplasmosis.

Koo L, Young LH.

Int Ophthalmol Clin. 2006 Spring;46(2):183-93. Review. No abstract available. PMID: 16770162 [PubMed - indexed for MEDLINE]Related articles

Cytomegalovirus retinitis.

Wiegand TW, Young LH.

Int Ophthalmol Clin. 2006 Spring;46(2):91-110. Review. No abstract available. PMID: 16770157 [PubMed - indexed for MEDLINE]Related articles

Ocular manifestations of helminthic infections: onchocersiasis, cysticercosis, toxocariasis, and diffuse unilateral subacute neuroretinitis.

Ament CS, Young LH.

Int Ophthalmol Clin. 2006 Spring;46(2):1-10. Review. No abstract available. PMID: 16770150 [PubMed - indexed for MEDLINE]Related articles

Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging.

Papaioannou GI, Kasapis C, Seip RL, Grey NJ, Katten D, Wackers FJ, Inzucchi SE, Engel S, Taylor A, Young LH, Chyun DA, Davey JA, Iskandrian AE, Ratner RE, Robinson EC, Carolan S, Heller GV.

J Nucl Cardiol. 2006 May-Jun;13(3):362-8.PMID: 16750781 [PubMed - indexed for MEDLINE]Related articles

Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart.

Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH.

Am J Physiol Heart Circ Physiol. 2006 Oct;291(4):H1927-34. Epub 2006 Apr 28.PMID: 16648175 [PubMed - indexed for MEDLINE]Related articlesFree article

Diagnostic and therapeutic challenges.

Mandava N, Bartlett H, Young LH, Brooks HL Jr.

Retina. 2006 Feb;26(2):214-8. No abstract available. PMID: 16467681 [PubMed - indexed for MEDLINE]Related articles

Future laser approaches in melanoma treatment.

Kim RY, Gragroudas ES, Young LH.

Int Ophthalmol Clin. 2006 Winter;46(1):27-39. Review. No abstract available. PMID: 16365553 [PubMed - indexed for MEDLINE]Related articles

Treatment options for metastatic tumors to the choroid.

Paul Chan RV, Young LH.

Semin Ophthalmol. 2005 Oct-Dec;20(4):207-16. Review.PMID: 16361217 [PubMed - indexed for MEDLINE]Related articles

Sympathetic ophthalmia.

Damico FM, Kiss S, Young LH.

Semin Ophthalmol. 2005 Jul-Sep;20(3):191-7. Review.PMID: 16282154 [PubMed - indexed for MEDLINE]Related articles

Vogt-Koyanagi-Harada disease.

Damico FM, Kiss S, Young LH.

Semin Ophthalmol. 2005 Jul-Sep;20(3):183-90. Review.PMID: 16282153 [PubMed - indexed for MEDLINE]Related articles

Ocular manifestations and treatment of syphilis.

Kiss S, Damico FM, Young LH.

Semin Ophthalmol. 2005 Jul-Sep;20(3):161-7. Review.PMID: 16282150 [PubMed - indexed for MEDLINE]Related articles

Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury.

Young LH, Balin BJ, Weis MT.

Cardiovasc Drug Rev. 2005 Fall;23(3):255-72. Review.PMID: 16252018 [PubMed - indexed for MEDLINE]Related articles

Sturge-Weber syndrome (choroidal hemangioma and glaucoma).

Chen TC, Young LH.

J Pediatr Ophthalmol Strabismus. 2005 Sep-Oct;42(5):320. No abstract available. PMID: 16250225 [PubMed - indexed for MEDLINE]Related articles

Diagnostic and therapeutic challenges.

Young LH, Gross JG, Lai JC, Shakin JL, Thompson JT.

Retina. 2005 Oct-Nov;25(7):930-5. No abstract available. PMID: 16205574 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.

Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR 3rd, Young LH.

Circ Res. 2005 Oct 28;97(9):872-9. Epub 2005 Sep 22.PMID: 16179588 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of complex mixtures in urban atmospheres for inhalation exposure studies.

Keeler GJ, Morishita M, Young LH.

Exp Toxicol Pathol. 2005 Jul;57 Suppl 1:19-29.PMID: 16092715 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase: a key stress signaling pathway in the heart.

Young LH, Li J, Baron SJ, Russell RR.

Trends Cardiovasc Med. 2005 Apr;15(3):110-8. Review.PMID: 16039971 [PubMed - indexed for MEDLINE]Related articles

Protein kinase C betaII peptide inhibitor exerts cardioprotective effects in rat cardiac ischemia/reperfusion injury.

Omiyi D, Brue RJ, Taormina P 2nd, Harvey M, Atkinson N, Young LH.

J Pharmacol Exp Ther. 2005 Aug;314(2):542-51. Epub 2005 May 5.PMID: 15878997 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C-zeta inhibition exerts cardioprotective effects in ischemia-reperfusion injury.

Phillipson A, Peterman EE, Taormina P Jr, Harvey M, Brue RJ, Atkinson N, Omiyi D, Chukwu U, Young LH.

Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H898-907. Epub 2005 Mar 25.PMID: 15792991 [PubMed - indexed for MEDLINE]Related articlesFree article

Dual mechanisms regulating AMPK kinase action in the ischemic heart.

Baron SJ, Li J, Russell RR 3rd, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH.

Circ Res. 2005 Feb 18;96(3):337-45. Epub 2005 Jan 13.PMID: 15653571 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of ultrafine particle number concentration and size distribution during a summer campaign in southwest Detroit.

Young LH, Keeler GJ.

J Air Waste Manag Assoc. 2004 Sep;54(9):1079-90.PMID: 15468661 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury.

Russell RR 3rd, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH.

J Clin Invest. 2004 Aug;114(4):495-503.PMID: 15314686 [PubMed - indexed for MEDLINE]Related articlesFree article

Diastolic function and type 1 diabetes.

Young LH.

Diabetes Care. 2004 Aug;27(8):2081-3. No abstract available. PMID: 15277445 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study.

Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Wittlin SD, Heller GV, Filipchuk N, Engel S, Ratner RE, Iskandrian AE; Detection of Ischemia in Asymptomatic Diabetics Investigators.

Diabetes Care. 2004 Aug;27(8):1954-61. Erratum in: Diabetes Care. 2005 Feb;28(2):504. PMID: 15277423 [PubMed - indexed for MEDLINE]Related articlesFree article