PubMed

Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly with Type 2 Diabetes Mellitus.

Sakurai T, Iimuro S, Araki A, Umegaki H, Ohashi Y, Yokono K, Ito H.

Gerontology. 2009 Oct 10. [Epub ahead of print]PMID: 19828932 [PubMed - as supplied by publisher]Related articles

[Anti-aging medicine: the evidence to the value of the antihypertensive drugs, hypoglycemic drugs and statins]

Okumachi Y, Yokono K.

Nippon Rinsho. 2009 Jul;67(7):1372-6. Review. Japanese. PMID: 19591288 [PubMed - indexed for MEDLINE]Related articles

Predictors of gastric myoelectrical activity in type 2 diabetes mellitus.

Hata N, Murata S, Maeda J, Yatani H, Kohno Y, Yokono K, Okano H.

J Clin Gastroenterol. 2009 May-Jun;43(5):429-36.PMID: 19564814 [PubMed - indexed for MEDLINE]Related articles

Hasegawa Dementia Scale - revised, for screening of early Alzheimer's disease in the elderly with type 2 diabetes.

Tsukamoto R, Akisaki T, Kuranaga M, Takata T, Yokono K, Sakurai T.

Geriatr Gerontol Int. 2009 Jun;9(2):213-5. No abstract available. PMID: 19490145 [PubMed - indexed for MEDLINE]Related articles

Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.

Hamada S, Hara K, Hamada T, Yasuda H, Moriyama H, Nakayama R, Nagata M, Yokono K.

Diabetes. 2009 Jun;58(6):1321-32. Epub 2009 Mar 3.PMID: 19258434 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoreactive T cell response in CD25-negative fraction of peripheral blood mononuclear cells in established type 1 diabetes.

Moriyama H, Kotani R, Katsuta A, Kameno M, Arai T, Okumachi Y, Kishi M, Yamada K, Yasuda H, Hara K, Yokono K, Nagata M.

Ann N Y Acad Sci. 2008 Dec;1150:278-81.PMID: 19120313 [PubMed - indexed for MEDLINE]Related articles

Intravenous administration of proinsulin 1 or 2-expressing fiber-mutant recombinant adenovirus vector protects against the development of diabetes in NOD mice.

Yamada K, Moriyama H, Okumachi Y, Arai T, Kameno M, Kishi M, Yasuda H, Hara K, Yokono K, Nagata M.

Ann N Y Acad Sci. 2008 Dec;1150:183-6.PMID: 19120291 [PubMed - indexed for MEDLINE]Related articles

NO-mediated cytotoxicity contributes to multiple low-dose streptozotocin-induced diabetes but not to NOD diabetes.

Yasuda H, Jin Z, Nakayama M, Yamada K, Kishi M, Okumachi Y, Arai T, Moriyama H, Yokono K, Nagata M.

Diabetes Res Clin Pract. 2009 Feb;83(2):200-7. Epub 2008 Dec 30.PMID: 19117633 [PubMed - indexed for MEDLINE]Related articles

Dilation of perforating arteries in rat brain in response to systemic hypotension is more sensitive and pronounced than that of pial arterioles: simultaneous visualization of perforating and cortical vessels by in-vivo microangiography.

Yoshino H, Sakurai T, Oizumi XS, Akisaki T, Wang X, Yokono K, Kondoh T, Kohmura E, Umentani K.

Microvasc Res. 2009 Mar;77(2):230-3. Epub 2008 Oct 18.PMID: 18992262 [PubMed - indexed for MEDLINE]Related articles

The double-edged effect of insulin on the neuronal cell death associated with hypoglycemia on the hippocampal slice culture.

Tanaka Y, Takata T, Satomi T, Sakurai T, Yokono K.

Kobe J Med Sci. 2008 Jul 18;54(2):E97-107.PMID: 18772618 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-dose warfarin functions as an immunomodulator to prevent cyclophosphamide-induced NOD diabetes.

Kurohara M, Yasuda H, Moriyama H, Nakayama M, Sakata M, Yamada K, Kotani R, Hara K, Yokono K, Nagata M.

Kobe J Med Sci. 2008 May 23;54(1):E1-13.PMID: 18772604 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of CO2-induced distensibility in cerebral arteries with chronic hypertension or vasospasm after subarachnoid hemorrhage.

Nakajima S, Kondoh T, Morishita A, Yamashita H, Kohmura E, Sakurai T, Yokono K, Umetani K.

Kobe J Med Sci. 2008 Feb 8;53(6):317-26.PMID: 18762726 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of hypoxia-inducible factor 1 by glucose availability under hypoxic conditions.

Zhou J, Hara K, Inoue M, Hamada S, Yasuda H, Moriyama H, Endo H, Hirota K, Yonezawa K, Nagata M, Yokono K.

Kobe J Med Sci. 2008 Feb 8;53(6):283-96.PMID: 18762723 [PubMed - indexed for MEDLINE]Related articlesFree article

[A case of elderly onset loss of consciousness due to bacterial meningitis and subsequent vasculitis]

Kameno M, Takata T, Yasuda H, Hara K, Okano H, Sakurai T, Nagata M, Yokono K.

Nippon Ronen Igakkai Zasshi. 2008 Jul;45(4):434-8. Japanese. PMID: 18753720 [PubMed - indexed for MEDLINE]Related articlesFree article

One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide.

Okumachi Y, Moriyama H, Kameno M, Arai T, Kishi M, Kurohara M, Yamada K, Yasuda H, Hara K, Yokono K, Nagata M.

Biochem Biophys Res Commun. 2008 Sep 26;374(3):581-6. Epub 2008 Jul 21.PMID: 18647597 [PubMed - indexed for MEDLINE]Related articles

[Diabetes mellitus and anti-aging]

Yokono K.

Nippon Ronen Igakkai Zasshi. 2008 Mar;45(2):152-4. Japanese. No abstract available. PMID: 18441484 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of recurrent but not spontaneous autoimmune diabetes by transplanted NOD islets adenovirally transduced with immunomodulating molecules.

Sakata M, Yasuda H, Moriyama H, Yamada K, Kotani R, Kurohara M, Okumachi Y, Kishi M, Arai T, Hara K, Hamada H, Yokono K, Nagata M.

Diabetes Res Clin Pract. 2008 Jun;80(3):352-9. Epub 2008 Apr 8.PMID: 18400329 [PubMed - indexed for MEDLINE]Related articles

[Clinical remarks of diabetes mellitus in the elderly]

Yokono K.

Nippon Ronen Igakkai Zasshi. 2007 Sep;44(5):572-4. Japanese. No abstract available. PMID: 18048998 [PubMed - indexed for MEDLINE]Related articlesFree article

Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity.

Wang X, Takata T, Sakurai T, Yokono K.

Eur J Neurosci. 2007 Oct;26(8):2142-50. Epub 2007 Oct 1.PMID: 17908170 [PubMed - indexed for MEDLINE]Related articles

Differential mini-mental state examination profiles of older people with diabetes mellitus with early Alzheimer's disease.

Sakurai T, Kuranaga M, Akisaki T, Takata T, Endo H, Yokono K.

J Am Geriatr Soc. 2007 Jun;55(6):955-6. No abstract available. PMID: 17537100 [PubMed - indexed for MEDLINE]Related articles

Modification of the Rb-binding domain of replication-competent adenoviral vector enhances cytotoxicity against human esophageal cancers via NF-kappaB activity.

Yamada K, Moriyama H, Yasuda H, Hara K, Maniwa Y, Hamada H, Yokono K, Nagata M.

Hum Gene Ther. 2007 May;18(5):389-400.PMID: 17518613 [PubMed - indexed for MEDLINE]Related articles

Immunological aspects of 'fulminant type 1 diabetes'.

Nagata M, Moriyama H, Kotani R, Yasuda H, Kishi M, Kurohara M, Hara K, Yokono K.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S99-103. Epub 2007 May 2.PMID: 17478003 [PubMed - indexed for MEDLINE]Related articles

Insulin as a T cell antigen in type 1 diabetes supported by the evidence from the insulin knockout NOD mice.

Moriyama H, Nagata M, Arai T, Okumachi Y, Yamada K, Kotani R, Yasuda H, Hara K, Yokono K.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S155-60. Epub 2007 Apr 24.PMID: 17459508 [PubMed - indexed for MEDLINE]Related articles

[Group B streptococcal vertebral osteomyelitis following superficial suppurative thrombophlebitis]

Ohji G, Nagata M, Hara K, Matsuzawa T, Hata N, Yasuda H, Sakurai T, Okano H, Yokono K.

Nippon Ronen Igakkai Zasshi. 2006 Sep;43(5):635-8. Japanese. PMID: 17073295 [PubMed - indexed for MEDLINE]Related articles

Carotid artery occlusion and collateral circulation in C57Black/6J mice detected by synchrotron radiation microangiography.

Tamaki M, Kidoguchi K, Mizobe T, Koyama J, Kondoh T, Sakurai T, Kohmura E, Yokono K, Umetani K.

Kobe J Med Sci. 2006;52(5):111-8.PMID: 17006051 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantification of distension in rat cerebral perforating arteries.

Morishita A, Kondoh T, Sakurai T, Ikeda M, Bhattacharjee AK, Nakajima S, Kohmura E, Yokono K, Umetani K.

Neuroreport. 2006 Oct 2;17(14):1549-53.PMID: 16957606 [PubMed - indexed for MEDLINE]Related articles

[Expected role of professional geriatric physicians in education for geriatric medicine]

Sakurai T, Yokono K.

Nippon Ronen Igakkai Zasshi. 2006 Jul;43(4):441-4. Review. Japanese. No abstract available. PMID: 16937927 [PubMed - indexed for MEDLINE]Related articles

Association between diastolic blood pressure and lower hemoglobin A1C and frontal brain atrophy in elderly subjects with diabetes mellitus.

Sakurai T, Kuranaga M, Takata T, Yamasaki K, Hirai H, Endo H, Yokono K.

J Am Geriatr Soc. 2006 Jun;54(6):1005-7. No abstract available. PMID: 16776802 [PubMed - indexed for MEDLINE]Related articles

In vivo X-ray angiography in the mouse brain using synchrotron radiation.

Kidoguchi K, Tamaki M, Mizobe T, Koyama J, Kondoh T, Kohmura E, Sakurai T, Yokono K, Umetani K.

Stroke. 2006 Jul;37(7):1856-61. Epub 2006 Jun 1.PMID: 16741182 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired response of perforating arteries to hypercapnia in chronic hyperglycemia.

Oizumi XS, Akisaki T, Kouta Y, Song XZ, Takata T, Kondoh T, Umetani K, Hirano M, Yamasaki K, Kohmura E, Yokono K, Sakurai T.

Kobe J Med Sci. 2006;52(1-2):27-35.PMID: 16609273 [PubMed - indexed for MEDLINE]Related articlesFree article

Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT).

Akisaki T, Sakurai T, Takata T, Umegaki H, Araki A, Mizuno S, Tanaka S, Ohashi Y, Iguchi A, Yokono K, Ito H.

Diabetes Metab Res Rev. 2006 Sep-Oct;22(5):376-84.PMID: 16506272 [PubMed - indexed for MEDLINE]Related articles

Neuroprotective effect of D-fructose-1,6-bisphosphate against beta-amyloid induced neurotoxicity in rat hippocampal organotypic slice culture: involvement of PLC and MEK/ERK signaling pathways.

Song X, Wu B, Takata T, Wang X, Oizumi XS, Akisaki T, Yokono K, Sakurai T.

Kobe J Med Sci. 2005;51(5-6):73-83.PMID: 16501318 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin.

Ohji G, Hidayat S, Nakashima A, Tokunaga C, Oshiro N, Yoshino K, Yokono K, Kikkawa U, Yonezawa K.

J Biochem. 2006 Jan;139(1):129-35.PMID: 16428328 [PubMed - indexed for MEDLINE]Related articles

[Cognitive dysfunction and dementia associated with elderly diabetes]

Kouta Y, Sakurai T, Yokono K.

Nippon Rinsho. 2006 Jan;64(1):119-23. Review. Japanese. PMID: 16408458 [PubMed - indexed for MEDLINE]Related articles

[Possible role of mitochondrial dysfunction in insulin resistance in the elderly]

Yokono K.

Nippon Rinsho. 2006 Jan;64(1):39-44. Review. Japanese. PMID: 16408445 [PubMed - indexed for MEDLINE]Related articles

E1B-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis.

Harada N, Maniwa Y, Yoshimura M, Nagata M, Hamada H, Yokono K, Okita Y.

Oncol Rep. 2005 Nov;14(5):1155-63.PMID: 16211279 [PubMed - indexed for MEDLINE]Related articles

[Management of hypertension with diabetes mellitus in the elderly]

Kurohara M, Yokono K.

Nippon Rinsho. 2005 Jun;63(6):1052-60. Review. Japanese. PMID: 15948390 [PubMed - indexed for MEDLINE]Related articles

[Suitable treatment and management for diabetic elderly]

Yokono K.

Nippon Ronen Igakkai Zasshi. 2005 Mar;42(2):152-4. Japanese. No abstract available. PMID: 15852640 [PubMed - indexed for MEDLINE]Related articles

A possible association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma2 gene with obesity in native Javanese in Indonesia.

Danawati CW, Nagata M, Moriyama H, Hara K, Yasuda H, Nakayama M, Kotani R, Yamada K, Sakata M, Kurohara M, Wiyono P, Asdie H, Sakaue M, Taniguchi H, Yokono K.

Diabetes Metab Res Rev. 2005 Sep-Oct;21(5):465-9.PMID: 15739197 [PubMed - indexed for MEDLINE]Related articles

Detection of autoreactive T cells in type 1 diabetes using coded autoantigens and an immunoglobulin-free cytokine ELISPOT assay: report from the fourth immunology of diabetes society T cell workshop.

Nagata M, Kotani R, Moriyama H, Yokono K, Roep BO, Peakman M.

Ann N Y Acad Sci. 2004 Dec;1037:10-5.PMID: 15699487 [PubMed - indexed for MEDLINE]Related articles

[Diabetes in elderly patients]

Yokono K.

Nippon Naika Gakkai Zasshi. 2004 Dec 10;93(12):2559-65. Review. Japanese. No abstract available. PMID: 15658485 [PubMed - indexed for MEDLINE]Related articles

Glycolysis regulates the induction of lactate utilization for synaptic potentials after hypoxia in the granule cell of guinea pig hippocampus.

Takata T, Yang B, Sakurai T, Okada Y, Yokono K.

Neurosci Res. 2004 Dec;50(4):467-74.PMID: 15567484 [PubMed - indexed for MEDLINE]Related articles

[Recent therapy and study in diabetic elderly]

Yokono K, Sakurai T.

Nippon Ronen Igakkai Zasshi. 2004 Jul;41(4):369-71. Review. Japanese. No abstract available. PMID: 15387274 [PubMed - indexed for MEDLINE]Related articles

T lymphocyte response against pancreatic beta cell antigens in fulminant Type 1 diabetes.

Kotani R, Nagata M, Imagawa A, Moriyama H, Yasuda H, Miyagawa J, Hanafusa T, Yokono K.

Diabetologia. 2004 Jul;47(7):1285-91. Epub 2004 Jul 9.PMID: 15243701 [PubMed - indexed for MEDLINE]Related articles

[Geriatric medicine and long-term care insurance]

Sakurai T, Song X, Yokono K.

Nippon Ronen Igakkai Zasshi. 2004 Mar;41(2):189-92. Japanese. PMID: 15148754 [PubMed - indexed for MEDLINE]Related articles

[Synaptic utilization of lactate/pyruvate and neural function in the aging]

Sakurai T, Yang B, Yokono K.

Nippon Ronen Igakkai Zasshi. 2003 Jul;40(4):344-7. Japanese. PMID: 12934564 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.

Chakrabarty S, Nagata M, Yasuda H, Wen L, Nakayama M, Chowdhury SA, Yamada K, Jin Z, Kotani R, Moriyama H, Shimozato O, Yagita H, Yokono K.

Clin Exp Immunol. 2003 Sep;133(3):318-25.PMID: 12930356 [PubMed - indexed for MEDLINE]Related articlesFree article

[Treatment of hypertension with diabetes mellitus in the elderly]

Yokono K.

Nippon Rinsho. 2003 Jul;61(7):1250-5. Review. Japanese. PMID: 12877093 [PubMed - indexed for MEDLINE]Related articles

Effects of lactate/pyruvate on synaptic plasticity in the hippocampal dentate gyrus.

Yang B, Sakurai T, Takata T, Yokono K.

Neurosci Res. 2003 Jul;46(3):333-7.PMID: 12804794 [PubMed - indexed for MEDLINE]Related articles

Tolerance mechanisms in murine autoimmune diabetes induced by anti-ICAM-1/LFA-1 mAb and anti-CD8 mAb.

Chowdhury SA, Nagata M, Yamada K, Nakayama M, Chakrabarty S, Jin Z, Kotani R, Yokono K.

Kobe J Med Sci. 2002 Dec;48(5-6):167-75.PMID: 12657834 [PubMed - indexed for MEDLINE]Related articlesFree article