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    Results: 1 to 50 of 149

    1.

    Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway.

    Walden HR, Kirby JA, Yeaman SJ, Gray J, Jones DE, Palmer JM.

    Hepatology. 2008 Dec;48(6):1874-84.PMID: 19003917 [PubMed - indexed for MEDLINE]Related articles

    2.

    Does impaired mitochondrial function affect insulin signaling and action in cultured human skeletal muscle cells?

    Brown AE, Elstner M, Yeaman SJ, Turnbull DM, Walker M.

    Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E97-102. Epub 2007 Oct 23.PMID: 17957036 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells.

    Brown AE, Yeaman SJ, Walker M.

    Mol Genet Metab. 2007 Aug;91(4):318-24. Epub 2007 Jun 14.PMID: 17572128 [PubMed - indexed for MEDLINE]Related articles

    4.

    Key role for ceramides in mediating insulin resistance in human muscle cells.

    Pickersgill L, Litherland GJ, Greenberg AS, Walker M, Yeaman SJ.

    J Biol Chem. 2007 Apr 27;282(17):12583-9. Epub 2007 Mar 3.PMID: 17337731 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Role of glycogen content in insulin resistance in human muscle cells.

    Litherland GJ, Morris NJ, Walker M, Yeaman SJ.

    J Cell Physiol. 2007 May;211(2):344-52.PMID: 17167773 [PubMed - indexed for MEDLINE]Related articles

    6.

    Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.

    Abbot EL, McCormack JG, Reynet C, Hassall DG, Buchan KW, Yeaman SJ.

    FEBS J. 2005 Jun;272(12):3004-14.PMID: 15955060 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Calpain inhibition and insulin action in cultured human muscle cells.

    Logie LJ, Brown AE, Yeaman SJ, Walker M.

    Mol Genet Metab. 2005 May;85(1):54-60. Epub 2005 Feb 16.PMID: 15862281 [PubMed - indexed for MEDLINE]Related articles

    8.

    Relationship between the inhibition of phosphatidic acid phosphohydrolase-1 by oleate and oleoyl-CoA ester and its apparent translocation.

    Elabbadi N, Day CP, Gamouh A, Zyad A, Yeaman SJ.

    Biochimie. 2005 May;87(5):437-43.PMID: 15820750 [PubMed - indexed for MEDLINE]Related articles

    9.

    Cultured muscle cells from insulin-resistant type 2 diabetes patients have impaired insulin, but normal 5-amino-4-imidazolecarboxamide riboside-stimulated, glucose uptake.

    McIntyre EA, Halse R, Yeaman SJ, Walker M.

    J Clin Endocrinol Metab. 2004 Jul;89(7):3440-8.PMID: 15240629 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Hormone-sensitive lipase--new roles for an old enzyme.

    Yeaman SJ.

    Biochem J. 2004 Apr 1;379(Pt 1):11-22. Review.PMID: 14725507 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase.

    Halse R, Fryer LG, McCormack JG, Carling D, Yeaman SJ.

    Diabetes. 2003 Jan;52(1):9-15.PMID: 12502487 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin.

    O'Rourke L, Gronning LM, Yeaman SJ, Shepherd PR.

    J Biol Chem. 2002 Nov 8;277(45):42557-62. Epub 2002 Aug 27.PMID: 12200416 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Conditionally immortalized cell lines as model systems for high-throughput biology in drug discovery.

    Daniele N, Halse R, Grinyo E, Yeaman SJ, Shepherd PR.

    Biochem Soc Trans. 2002 Aug;30(4):800-2.PMID: 12196201 [PubMed - indexed for MEDLINE]Related articles

    14.

    Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids.

    Elabbadi N, Day CP, Virden R, Yeaman SJ.

    Lipids. 2002 Jan;37(1):69-73.PMID: 11876265 [PubMed - indexed for MEDLINE]Related articles

    15.

    Investigation of a mechanism for accelerated breakdown of immune tolerance to the primary biliary cirrhosis-associated autoantigen, pyruvate dehydrogenase complex.

    Jones DE, Palmer JM, Bennett K, Robe AJ, Yeaman SJ, Robertson H, Bassendine MF, Burt AD, Kirby JA.

    Lab Invest. 2002 Feb;82(2):211-9.PMID: 11850534 [PubMed - indexed for MEDLINE]Related articles

    16.

    Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation during the lactation cycle of the rat.

    Clifford GM, Kraemer FB, Yeaman SJ, Vernon RG.

    Metabolism. 2001 Nov;50(11):1264-9.PMID: 11699042 [PubMed - indexed for MEDLINE]Related articles

    17.

    Regulation of glycogen synthesis in human muscle cells.

    Yeaman SJ, Armstrong JL, Bonavaud SM, Poinasamy D, Pickersgill L, Halse R.

    Biochem Soc Trans. 2001 Aug;29(Pt 4):537-41. Review.PMID: 11498024 [PubMed - indexed for MEDLINE]Related articles

    18.

    Insulin and leptin acutely regulate cholesterol ester metabolism in macrophages by novel signaling pathways.

    O'Rourke L, Yeaman SJ, Shepherd PR.

    Diabetes. 2001 May;50(5):955-61.PMID: 11334438 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells.

    Halse R, Pearson SL, McCormack JG, Yeaman SJ, Taylor R.

    Diabetes. 2001 May;50(5):1102-9.PMID: 11334414 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells.

    Halse R, Bonavaud SM, Armstrong JL, McCormack JG, Yeaman SJ.

    Diabetes. 2001 Apr;50(4):720-6.PMID: 11289034 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Secretory autoantibodies in primary biliary cirrhosis (PBC).

    Palmer JM, Doshi M, Kirby JA, Yeaman SJ, Bassendine MF, Jones DE.

    Clin Exp Immunol. 2000 Dec;122(3):423-8.PMID: 11122250 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Experimental autoimmune cholangitis: a mouse model of immune-mediated cholangiopathy.

    Jones DE, Palmer JM, Kirby JA, De Cruz DJ, McCaughan GW, Sedgwick JD, Yeaman SJ, Burt AD, Bassendine MF.

    Liver. 2000 Oct;20(5):351-6.PMID: 11092252 [PubMed - indexed for MEDLINE]Related articles

    23.

    Regulation of glycogen synthesis by amino acids in cultured human muscle cells.

    Armstrong JL, Bonavaud SM, Toole BJ, Yeaman SJ.

    J Biol Chem. 2001 Jan 12;276(2):952-6.PMID: 11013237 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Decreased insulin responsiveness of glucose uptake in cultured human skeletal muscle cells from insulin-resistant nondiabetic relatives of type 2 diabetic families.

    Jackson S, Bagstaff SM, Lynn S, Yeaman SJ, Turnbull DM, Walker M.

    Diabetes. 2000 Jul;49(7):1169-77.PMID: 10909975 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Autoreactive responses to pyruvate dehydrogenase complex in the pathogenesis of primary biliary cirrhosis.

    Yeaman SJ, Kirby JA, Jones DE.

    Immunol Rev. 2000 Apr;174:238-49. Review.PMID: 10807520 [PubMed - indexed for MEDLINE]Related articles

    26.

    Specificity determinants for the pyruvate dehydrogenase component reaction mapped with mutated and prosthetic group modified lipoyl domains.

    Gong X, Peng T, Yakhnin A, Zolkiewski M, Quinn J, Yeaman SJ, Roche TE.

    J Biol Chem. 2000 May 5;275(18):13645-53.PMID: 10788482 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes.

    Clifford GM, Londos C, Kraemer FB, Vernon RG, Yeaman SJ.

    J Biol Chem. 2000 Feb 18;275(7):5011-5.PMID: 10671541 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Breakdown of tolerance to pyruvate dehydrogenase complex in experimental autoimmune cholangitis: a mouse model of primary biliary cirrhosis.

    Jones DE, Palmer JM, Yeaman SJ, Kirby JA, Bassendine MF.

    Hepatology. 1999 Jul;30(1):65-70.PMID: 10385640 [PubMed - indexed for MEDLINE]Related articles

    29.

    Characterization of the autoantibody responses to recombinant E3 binding protein (protein X) of pyruvate dehydrogenase in primary biliary cirrhosis.

    Palmer JM, Jones DE, Quinn J, McHugh A, Yeaman SJ.

    Hepatology. 1999 Jul;30(1):21-6.PMID: 10385634 [PubMed - indexed for MEDLINE]Related articles

    30.

    Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucagon is associated with inhibition of ERK2 and p70 S6 kinase.

    Dixon M, Agius L, Yeaman SJ, Day CP.

    Hepatology. 1999 May;29(5):1418-24.PMID: 10216124 [PubMed - indexed for MEDLINE]Related articles

    31.

    T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC).

    Palmer JM, Diamond AG, Yeaman SJ, Bassendine MF, Jones DE.

    Clin Exp Immunol. 1999 Apr;116(1):133-9.PMID: 10209517 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Enhanced ultrasensitive detection of structurally diverse antigens using a single immuno-PCR assay protocol.

    Case MC, Burt AD, Hughes J, Palmer JM, Collier JD, Bassendine MF, Yeaman SJ, Hughes MA, Major GN.

    J Immunol Methods. 1999 Feb 1;223(1):93-106. Erratum in: J Immunol Methods 1999 Jun 24;226(1-2):189-90. PMID: 10037237 [PubMed - indexed for MEDLINE]Related articles

    33.

    Control of glycogen synthesis in cultured human muscle cells.

    Halse R, Rochford JJ, McCormack JG, Vandenheede JR, Hemmings BA, Yeaman SJ.

    J Biol Chem. 1999 Jan 8;274(2):776-80.PMID: 9873015 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Dephosphorylation of perilipin by protein phosphatases present in rat adipocytes.

    Clifford GM, McCormick DK, Londos C, Vernon RG, Yeaman SJ.

    FEBS Lett. 1998 Sep 11;435(1):125-9.PMID: 9755872 [PubMed - indexed for MEDLINE]Related articles

    35.

    Three-dimensional structure of the major autoantigen in primary biliary cirrhosis.

    Howard MJ, Fuller C, Broadhurst RW, Perham RN, Tang JG, Quinn J, Diamond AG, Yeaman SJ.

    Gastroenterology. 1998 Jul;115(1):139-46.PMID: 9649469 [PubMed - indexed for MEDLINE]Related articles

    36.

    Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis.

    Thomson RK, Davis Z, Palmer JM, Arthur MJ, Yeaman SJ, Chapman CJ, Spellerberg MB, Stevenson FK.

    J Hepatol. 1998 Apr;28(4):582-94.PMID: 9566826 [PubMed - indexed for MEDLINE]Related articles

    37.

    Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes.

    Peak M, Rochford JJ, Borthwick AC, Yeaman SJ, Agius L.

    Diabetologia. 1998 Jan;41(1):16-25.PMID: 9498625 [PubMed - indexed for MEDLINE]Related articles

    38.

    Translocation of perilipin and hormone-sensitive lipase in response to lipolytic hormones.

    Clifford GM, McCormick DK, Vernon RG, Yeaman SJ.

    Biochem Soc Trans. 1997 Nov;25(4):S672. No abstract available. PMID: 9450100 [PubMed - indexed for MEDLINE]Related articles

    39.

    The human biliary epithelial cell plasma membrane antigen in primary biliary cirrhosis: pyruvate dehydrogenase X?

    Joplin RE, Wallace LL, Lindsay JG, Palmer JM, Yeaman SJ, Neuberger JM.

    Gastroenterology. 1997 Nov;113(5):1727-33.PMID: 9352878 [PubMed - indexed for MEDLINE]Related articles

    40.

    T cell responses to natural human proteins in primary biliary cirrhosis.

    Jones DE, Palmer JM, Yeaman SJ, Bassendine MF, Diamond AG.

    Clin Exp Immunol. 1997 Mar;107(3):562-8.PMID: 9067533 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis.

    Bassendine MF, Jones DE, Yeaman SJ.

    Semin Liver Dis. 1997 Feb;17(1):49-60. Review.PMID: 9089910 [PubMed - indexed for MEDLINE]Related articles

    42.

    T cell responses to tuberculin purified protein derivative in primary biliary cirrhosis: evidence for defective T cell function.

    Jones DE, Palmer JM, Leon MP, Yeaman SJ, Bassendine MF, Diamond AG.

    Gut. 1997 Feb;40(2):277-83.PMID: 9071945 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Transforming growth factor beta increases the activity of phosphatidate phosphohydrolase-1 in rat hepatocytes.

    Dixon MC, Yeaman SJ, Agius L, Day CP.

    Biochem Biophys Res Commun. 1997 Jan 13;230(2):365-9.PMID: 9016785 [PubMed - indexed for MEDLINE]Related articles

    44.

    Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

    Hurel SJ, Rochford JJ, Borthwick AC, Wells AM, Vandenheede JR, Turnbull DM, Yeaman SJ.

    Biochem J. 1996 Dec 15;320 ( Pt 3):871-7.PMID: 9003374 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Evidence for a multi-domain structure for hormone-sensitive lipase.

    Smith GM, Garton AJ, Aitken A, Yeaman SJ.

    FEBS Lett. 1996 Oct 28;396(1):90-4.PMID: 8906873 [PubMed - indexed for MEDLINE]Related articles

    46.

    Effects of novel synthetic sterol probes on enzymes of cholesterol metabolism in cell-free and cellular systems.

    Harte RA, Yeaman SJ, McElhinney J, Suckling CJ, Jackson B, Suckling KE.

    Chem Phys Lipids. 1996 Sep 16;83(1):45-59.PMID: 8858832 [PubMed - indexed for MEDLINE]Related articles

    47.

    Down-regulation of hormone-sensitive lipase in sterol ester-laden J774.2 macrophages.

    Jepson CA, Harrison JA, Kraemer FB, Yeaman SJ.

    Biochem J. 1996 Aug 15;318 ( Pt 1):173-7.PMID: 8761468 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages.

    Graham A, Angell AD, Jepson CA, Yeaman SJ, Hassall DG.

    Atherosclerosis. 1996 Feb;120(1-2):135-45.PMID: 8645354 [PubMed - indexed for MEDLINE]Related articles

    49.

    Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.

    Christie AW, McCormick DK, Emmison N, Kraemer FB, Alberti KG, Yeaman SJ.

    Diabetologia. 1996 Jan;39(1):45-53.PMID: 8720602 [PubMed - indexed for MEDLINE]Related articles

    50.

    The effect of acute (60 minute) insulin stimulation upon human skeletal muscle glycogen synthase and protein phosphatase-1 in non-insulin-dependent diabetic patients and control subjects.

    Barriocanal LA, Borthwick AC, Stewart M, Wells A, Hurel SJ, Yeaman SJ, Taylor R.

    Diabet Med. 1995 Dec;12(12):1110-5.PMID: 8750222 [PubMed - indexed for MEDLINE]Related articles

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