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The freshwater Amazonian stingray, Potamotrygon motoro, up-regulates glutamine synthetase activity and protein abundance, and accumulates glutamine when exposed to brackish (15 per thousand) water.
Ip YK, Loong AM, Ching B, Tham GH, Wong WP, Chew SF.
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Environmental ammonia exposure induces oxidative stress in gills and brain of Boleophthalmus boddarti (mudskipper).
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Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival.
Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F.
Diabetes. 2009 Oct;58(10):2292-302. Epub 2009 Jul 8.PMID: 19587358 [PubMed - indexed for MEDLINE]Related articles
Acute ammonia toxicity and the protective effects of methionine sulfoximine on the swamp eel, Monopterus albus.
Tng YY, Chew SF, Wee NL, Wong FK, Wong WP, Tok CY, Ip YK.
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Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor.
Zhang X, Halvorsen K, Zhang CZ, Wong WP, Springer TA.
Science. 2009 Jun 5;324(5932):1330-4.PMID: 19498171 [PubMed - indexed for MEDLINE]Related articlesFree article
Glutamine accumulation and up-regulation of glutamine synthetase activity in the swamp eel, Monopterus albus (Zuiew), exposed to brackish water.
Tok CY, Chew SF, Peh WY, Loong AM, Wong WP, Ip YK.
J Exp Biol. 2009 May;212(Pt 9):1248-58.PMID: 19376945 [PubMed - indexed for MEDLINE]Related articlesFree article
Beyond the frame rate: measuring high-frequency fluctuations with light-intensity modulation.
Wong WP, Halvorsen K.
Opt Lett. 2009 Feb 1;34(3):277-9.PMID: 19183630 [PubMed]Related articles
After-hour physiotherapy services in a tertiary general hospital.
Lim ECW, Liu J, Yeung MT, Wong WP.
Physiother Theory Pract. 2008 Nov-Dec;24(6):423-9.PMID: 19117233 [PubMed - indexed for MEDLINE]Related articles
Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance.
Wong WP, Scott DW, Chuang CL, Zhang S, Liu H, Ferreira A, Saafi EL, Choong YS, Cooper GJ.
Diabetes. 2008 Oct;57(10):2737-44. Epub 2008 Jul 15.PMID: 18633116 [PubMed - indexed for MEDLINE]Related articlesFree article
MMP-3 response to compressive forces in vitro and in vivo.
Chang HH, Wu CB, Chen YJ, Weng CY, Wong WP, Chen YJ, Chang BE, Chen MH, Yao CC.
J Dent Res. 2008 Jul;87(7):692-6.PMID: 18573993 [PubMed - indexed for MEDLINE]Related articles
Renal corpuscle of the african lungfish Protopterus dolloi: structural and histochemical modifications during aestivation.
Ojeda JL, Wong WP, Ip YK, Icardo JM.
Anat Rec (Hoboken). 2008 Sep;291(9):1156-72.PMID: 18521897 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of hypoxia on the energy status and nitrogen metabolism of African lungfish during aestivation in a mucus cocoon.
Loong AM, Ang SF, Wong WP, Pörtner HO, Bock C, Wittig R, Bridges CR, Chew SF, Ip YK.
J Comp Physiol B. 2008 Sep;178(7):853-65. Epub 2008 May 27.PMID: 18504593 [PubMed - indexed for MEDLINE]Related articles
The structural characteristics of the heart ventricle of the African lungfish Protopterus dolloi: freshwater and aestivation.
Icardo JM, Amelio D, Garofalo F, Colvee E, Cerra MC, Wong WP, Tota B, Ip YK.
J Anat. 2008 Aug;213(2):106-19.PMID: 18482286 [PubMed - in process]Related articles
Imaging biomolecular interactions by fast three-dimensional tracking of laser-confined carrier particles.
Heinrich V, Wong WP, Halvorsen K, Evans E.
Langmuir. 2008 Feb 19;24(4):1194-203. Epub 2008 Jan 17.PMID: 18198910 [PubMed - indexed for MEDLINE]Related articles
Mechanisms of and defense against acute ammonia toxicity in the aquatic Chinese soft-shelled turtle, Pelodiscus sinensis.
Ip YK, Lee SM, Wong WP, Chew SF.
Aquat Toxicol. 2008 Jan 31;86(2):185-96. Epub 2007 Nov 4.PMID: 18068826 [PubMed - indexed for MEDLINE]Related articles
Increased urea synthesis and/or suppressed ammonia production in the African lungfish, Protopterus annectens, during aestivation in air or mud.
Loong AM, Pang CY, Hiong KC, Wong WP, Chew SF, Ip YK.
J Comp Physiol B. 2008 Mar;178(3):351-63. Epub 2007 Dec 6.PMID: 18058110 [PubMed - indexed for MEDLINE]Related articles
Differential NOS expression in freshwater and aestivating Protopterus dolloi (lungfish): heart vs kidney readjustments.
Amelio D, Garofalo F, Brunelli E, Loong AM, Wong WP, Ip YK, Tota B, Cerra MC.
Nitric Oxide. 2008 Feb;18(1):1-10. Epub 2007 Oct 30.PMID: 18022402 [PubMed - indexed for MEDLINE]Related articles
Changes in tissue free amino acid contents, branchial Na+/K+ -ATPase activity and bimodal breathing pattern in the freshwater climbing perch, Anabas testudineus (Bloch), during seawater acclimation.
Chang EW, Loong AM, Wong WP, Chew SF, Wilson JM, Ip YK.
J Exp Zool A Ecol Genet Physiol. 2007 Dec 1;307(12):708-23.PMID: 17963240 [PubMed - indexed for MEDLINE]Related articles
Defense against environmental ammonia toxicity in the African lungfish, Protopterus aethiopicus: Bimodal breathing, skin ammonia permeability and urea synthesis.
Loong AM, Tan JY, Wong WP, Chew SF, Ip YK.
Aquat Toxicol. 2007 Nov 15;85(1):76-86. Epub 2007 Aug 12.PMID: 17881067 [PubMed - indexed for MEDLINE]Related articles
Active ammonia excretion in the giant mudskipper, Periophthalmodon schlosseri (Pallas), during emersion.
Chew SF, Sim MY, Phua ZC, Wong WP, Ip YK.
J Exp Zool A Ecol Genet Physiol. 2007 Jun 1;307(6):357-69.PMID: 17405165 [PubMed - indexed for MEDLINE]Related articles
The effect of integration time on fluctuation measurements: calibrating an optical trap in the presence of motion blur.
Opt Express. 2006 Dec 11;14(25):12517-31.PMID: 19529687 [PubMed - in process]Related articles
Active ammonia transport and excretory nitrogen metabolism in the climbing perch, Anabas testudineus, during 4 days of emersion or 10 minutes of forced exercise on land.
Tay YL, Loong AM, Hiong KC, Lee SJ, Tng YY, Wee NL, Lee SM, Wong WP, Chew SF, Wilson JM, Ip YK.
J Exp Biol. 2006 Nov;209(Pt 22):4475-89.PMID: 17079718 [PubMed - indexed for MEDLINE]Related articlesFree article
Nitrogen metabolism and excretion in the aquatic chinese soft-shelled turtle, Pelodiscus sinensis, exposed to a progressive increase in ambient salinity.
Lee SM, Wong WP, Hiong KC, Loong AM, Chew SF, Ip YK.
J Exp Zool A Comp Exp Biol. 2006 Dec 1;305(12):995-1009.PMID: 17068799 [PubMed - indexed for MEDLINE]Related articles
Characterization of cDNAs encoding cholesterol side chain cleavage and 3beta-hydroxysteroid dehydrogenase in the freshwater stingray Potamotrygon motoro.
Scott Nunez B, Evans AN, Simpson MA, Wong WP, Ip YK.
Comp Biochem Physiol B Biochem Mol Biol. 2006 Nov-Dec;145(3-4):306-17. Epub 2006 Aug 5.PMID: 16978895 [PubMed - indexed for MEDLINE]Related articles
Postprandial increases in nitrogenous excretion and urea synthesis in the Chinese soft-shelled turtle, Pelodiscus sinensis.
Lee SM, Wong WP, Loong AM, Hiong KC, Chew SF, Ip YK.
J Comp Physiol B. 2007 Jan;177(1):19-29. Epub 2006 Jul 13.PMID: 16838133 [PubMed - indexed for MEDLINE]Related articles
Microanatomy and ultrastructure of the kidney of the African lungfish Protopterus dolloi.
Ojeda JL, Icardo JM, Wong WP, Ip YK.
Anat Rec A Discov Mol Cell Evol Biol. 2006 Jun;288(6):609-25.PMID: 16703593 [PubMed - indexed for MEDLINE]Related articlesFree article
Light induces an increase in the pH of and a decrease in the ammonia concentration in the extrapallial fluid of the giant clam Tridacna squamosa.
Ip YK, Loong AM, Hiong KC, Wong WP, Chew SF, Reddy K, Sivaloganathan B, Ballantyne JS.
Physiol Biochem Zool. 2006 May-Jun;79(3):656-64. Epub 2006 Apr 12.PMID: 16691530 [PubMed - indexed for MEDLINE]Related articles
Exposure to brackish water, upon feeding, leads to enhanced conservation of nitrogen and increased urea synthesis and retention in the Asian freshwater stingray Himantura signifer.
Chew SF, Poothodiyil NK, Wong WP, Ip YK.
J Exp Biol. 2006 Feb;209(Pt 3):484-92.PMID: 16424098 [PubMed - indexed for MEDLINE]Related articlesFree article
Comparative analysis of BMPR2 gene and its mutations in idiopathic pulmonary arterial hypertension.
Wong WP, Knowles JA, Morse JH.
Chest. 2005 Dec;128(6 Suppl):615S. No abstract available. PMID: 16373869 [PubMed - indexed for MEDLINE]Related articlesFree article
The interplay of increased urea synthesis and reduced ammonia production in the African lungfish Protopterus aethiopicus during 46 days of aestivation in a mucus cocoon.
Ip YK, Yeo PJ, Loong AM, Hiong KC, Wong WP, Chew SF.
J Exp Zool A Comp Exp Biol. 2005 Dec 1;303(12):1054-65.PMID: 16254918 [PubMed - indexed for MEDLINE]Related articles
Biological physics: rare returns on lost effort.
Wong WP, Evans E.
Nature. 2005 Sep 8;437(7056):198-9. No abstract available. PMID: 16148917 [PubMed - indexed for MEDLINE]Related articles
The African sharptooth catfish Clarias gariepinus can tolerate high levels of ammonia in its tissues and organs during four days of aerial exposure.
Ip YK, Lau IY, Wong WP, Lee SL, Chew SF.
Physiol Biochem Zool. 2005 Jul-Aug;78(4):630-40. Epub 2005 May 17.PMID: 15957117 [PubMed - indexed for MEDLINE]Related articles
Marine (Taeniura lymma) and freshwater (Himantura signifer) elasmobranchs synthesize urea for osmotic water retention.
Ip YK, Tam WL, Wong WP, Chew SF.
Physiol Biochem Zool. 2005 Jul-Aug;78(4):610-9. Epub 2005 May 17.PMID: 15957115 [PubMed - indexed for MEDLINE]Related articles
Chronic and acute ammonia toxicity in mudskippers, Periophthalmodon schlosseri and Boleophthalmus boddaerti: brain ammonia and glutamine contents, and effects of methionine sulfoximine and MK801.
Ip YK, Leong MW, Sim MY, Goh GS, Wong WP, Chew SF.
J Exp Biol. 2005 May;208(Pt 10):1993-2004.PMID: 15879078 [PubMed - indexed for MEDLINE]Related articlesFree article
Ventricle and outflow tract of the African lungfish Protopterus dolloi.
Icardo JM, Brunelli E, Perrotta I, Colvee E, Wong WP, Ip YK.
J Morphol. 2005 Jul;265(1):43-51.PMID: 15858831 [PubMed - indexed for MEDLINE]Related articles
Ornithine-urea cycle and urea synthesis in African lungfishes, Protopterus aethiopicus and Protopterus annectens, exposed to terrestrial conditions for six days.
Loong AM, Hiong KC, Lee SM, Wong WP, Chew SF, Ip YK.
J Exp Zool A Comp Exp Biol. 2005 May 1;303(5):354-65.PMID: 15828011 [PubMed - indexed for MEDLINE]Related articles
Effects of intra-peritoneal injection with NH4Cl, urea, or NH4Cl+urea on nitrogen excretion and metabolism in the African lungfish Protopterus dolloi.
Ip YK, Peh BK, Tam WL, Wong WP, Chew SF.
J Exp Zool A Comp Exp Biol. 2005 Apr 1;303(4):272-82.PMID: 15776416 [PubMed - indexed for MEDLINE]Related articles
The African lungfish, Protopterus dolloi, detoxifies ammonia to urea during environmental ammonia exposure.
Chew SF, Ho L, Ong TF, Wong WP, Ip YK.
Physiol Biochem Zool. 2005 Jan-Feb;78(1):31-9.PMID: 15702460 [PubMed - indexed for MEDLINE]Related articles
Exposure to air, but not seawater, increases the glutamine content and the glutamine synthetase activity in the marsh clam Polymesoda expansa.
Hiong KC, Peh WY, Loong AM, Wong WP, Chew SF, Ip YK.
J Exp Biol. 2004 Dec;207(Pt 26):4605-14.PMID: 15579556 [PubMed - indexed for MEDLINE]Related articlesFree article
Heart inflow tract of the African lungfish Protopterus dolloi.
Icardo JM, Ojeda JL, Colvee E, Tota B, Wong WP, Ip YK.
J Morphol. 2005 Jan;263(1):30-8.PMID: 15536649 [PubMed - indexed for MEDLINE]Related articles
Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum.
Wang Y, Lu G, Wong WP, Vliegenthart JF, Gerwig GJ, Lam KS, Cooper GJ, Xu A.
Proteomics. 2004 Dec;4(12):3933-42.PMID: 15378692 [PubMed - indexed for MEDLINE]Related articles
BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease.
Roberts KE, McElroy JJ, Wong WP, Yen E, Widlitz A, Barst RJ, Knowles JA, Morse JH.
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The ammonotelic African lungfish, Protopterus dolloi, increases the rate of urea synthesis and becomes ureotelic after feeding.
Lim CK, Wong WP, Lee SM, Chew SF, Ip YK.
J Comp Physiol B. 2004 Oct;174(7):555-64. Epub 2004 Aug 17.PMID: 15316727 [PubMed - indexed for MEDLINE]Related articles
Postprandial increases in nitrogenous excretion and urea synthesis in the giant mudskipper Periophthalmodon schlosseri.
Ip YK, Lim CK, Lee SL, Wong WP, Chew SF.
J Exp Biol. 2004 Aug;207(Pt 17):3015-23.PMID: 15277556 [PubMed - indexed for MEDLINE]Related articlesFree article
The crab-eating frog, Rana cancrivora, up-regulates hepatic carbamoyl phosphate synthetase I activity and tissue osmolyte levels in response to increased salinity.
Wright P, Anderson P, Weng L, Frick N, Wong WP, Ip YK.
J Exp Zool A Comp Exp Biol. 2004 Jul 1;301(7):559-68.PMID: 15229866 [PubMed - indexed for MEDLINE]Related articles
African sharptooth catfish Clarias gariepinus does not detoxify ammonia to urea or amino acids but actively excretes ammonia during exposure to environmental ammonia.
Ip YK, Zubaidah RM, Liew PC, Loong AM, Hiong KC, Wong WP, Chew SF.
Physiol Biochem Zool. 2004 Mar-Apr;77(2):242-54.PMID: 15095244 [PubMed - indexed for MEDLINE]Related articles
Excretory nitrogen metabolism in the Chinese fire-belly newt Cynops orientalis in water, on land, or in high concentrations of environmental ammonia.
Weng L, Wong WP, Chew SF, Ip YK.
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Effect of manual hyperinflation on haemodynamics in an animal model.
Anning L, Paratz J, Wong WP, Wilson K.
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A comparison of the effects of environmental ammonia exposure on the Asian freshwater stingray Himantura signifer and the Amazonian freshwater stingray Potamotrygon motoro.
Ip YK, Tam WL, Wong WP, Loong AM, Hiong KC, Ballantyne JS, Chew SF.
J Exp Biol. 2003 Oct;206(Pt 20):3625-33.PMID: 12966054 [PubMed - indexed for MEDLINE]Related articlesFree article
Urea synthesis in the African lungfish Protopterus dolloi--hepatic carbamoyl phosphate synthetase III and glutamine synthetase are upregulated by 6 days of aerial exposure.
Chew SF, Ong TF, Ho L, Tam WL, Loong AM, Hiong KC, Wong WP, Ip YK.
J Exp Biol. 2003 Oct;206(Pt 20):3615-24.PMID: 12966053 [PubMed - indexed for MEDLINE]Related articlesFree article
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Science. 2009 Jun 5; 324(5932):1330-4.
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Diabetes. 2008 Oct; 57(10):2737-44.
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Br Med J. 1976 Sep 18; 2(6037):698-9.
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