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    Results: 30

    1.

    Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.

    Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, Heynck S, Beroukhim R, Lin W, Winckler W, Shah K, LaFramboise T, Moriarty WF, Hanna M, Tolosi L, Rahnenführer J, Verhaak R, Chiang D, Getz G, Hellmich M, Wolf J, Girard L, Peyton M, Weir BA, Chen TH, Greulich H, Barretina J, Shapiro GI, Garraway LA, Gazdar AF, Minna JD, Meyerson M, Wong KK, Thomas RK.

    J Clin Invest. 2009 Jun;119(6):1727-40. doi: 10.1172/JCI37127. Epub 2009 May 18.PMID: 19451690 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A flexible rank-based framework for detecting copy number aberrations from array data.

    LaFramboise T, Winckler W, Thomas RK.

    Bioinformatics. 2009 Mar 15;25(6):722-8. Epub 2009 Jan 28.PMID: 19176555 [PubMed - indexed for MEDLINE]Related articles

    3.

    Genome-wide functional synergy between amplified and mutated genes in human breast cancer.

    Nikolsky Y, Sviridov E, Yao J, Dosymbekov D, Ustyansky V, Kaznacheev V, Dezso Z, Mulvey L, Macconaill LE, Winckler W, Serebryiskaya T, Nikolskaya T, Polyak K.

    Cancer Res. 2008 Nov 15;68(22):9532-40.PMID: 19010930 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Somatic mutations affect key pathways in lung adenocarcinoma.

    Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK.

    Nature. 2008 Oct 23;455(7216):1069-75.PMID: 18948947 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Drug-sensitive FGFR2 mutations in endometrial carcinoma.

    Dutt A, Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C, Nicoletti R, Winckler W, Grewal R, Hanna M, Wyhs N, Ziaugra L, Richter DJ, Trovik J, Engelsen IB, Stefansson IM, Fennell T, Cibulskis K, Zody MC, Akslen LA, Gabriel S, Wong KK, Sellers WR, Meyerson M, Greulich H.

    Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8713-7. Epub 2008 Jun 13.PMID: 18552176 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Major copy proportion analysis of tumor samples using SNP arrays.

    Li C, Beroukhim R, Weir BA, Winckler W, Garraway LA, Sellers WR, Meyerson M.

    BMC Bioinformatics. 2008 Apr 21;9:204.PMID: 18426588 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Modeling genomic diversity and tumor dependency in malignant melanoma.

    Lin WM, Baker AC, Beroukhim R, Winckler W, Feng W, Marmion JM, Laine E, Greulich H, Tseng H, Gates C, Hodi FS, Dranoff G, Sellers WR, Thomas RK, Meyerson M, Golub TR, Dummer R, Herlyn M, Getz G, Garraway LA.

    Cancer Res. 2008 Feb 1;68(3):664-73.PMID: 18245465 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Characterizing the cancer genome in lung adenocarcinoma.

    Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, Broderick S, Chang AC, Chiang DY, Chirieac LR, Cho J, Fujii Y, Gazdar AF, Giordano T, Greulich H, Hanna M, Johnson BE, Kris MG, Lash A, Lin L, Lindeman N, Mardis ER, McPherson JD, Minna JD, Morgan MB, Nadel M, Orringer MB, Osborne JR, Ozenberger B, Ramos AH, Robinson J, Roth JA, Rusch V, Sasaki H, Shepherd F, Sougnez C, Spitz MR, Tsao MS, Twomey D, Verhaak RG, Weinstock GM, Wheeler DA, Winckler W, Yoshizawa A, Yu S, Zakowski MF, Zhang Q, Beer DG, Wistuba II, Watson MA, Garraway LA, Ladanyi M, Travis WD, Pao W, Rubin MA, Gabriel SB, Gibbs RA, Varmus HE, Wilson RK, Lander ES, Meyerson M.

    Nature. 2007 Dec 6;450(7171):893-8. Epub 2007 Nov 4.PMID: 17982442 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.

    Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, Tuomi T, Gaudet D, Boström KB, Walker M, Hitman G, Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, Daly MJ, Frayling TM, Groop L, Altshuler D.

    Diabetes. 2007 Mar;56(3):685-93.PMID: 17327436 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    High-throughput oncogene mutation profiling in human cancer.

    Thomas RK, Baker AC, Debiasi RM, Winckler W, Laframboise T, Lin WM, Wang M, Feng W, Zander T, MacConaill L, Lee JC, Nicoletti R, Hatton C, Goyette M, Girard L, Majmudar K, Ziaugra L, Wong KK, Gabriel S, Beroukhim R, Peyton M, Barretina J, Dutt A, Emery C, Greulich H, Shah K, Sasaki H, Gazdar A, Minna J, Armstrong SA, Mellinghoff IK, Hodi FS, Dranoff G, Mischel PS, Cloughesy TF, Nelson SF, Liau LM, Mertz K, Rubin MA, Moch H, Loda M, Catalona W, Fletcher J, Signoretti S, Kaye F, Anderson KC, Demetri GD, Dummer R, Wagner S, Herlyn M, Sellers WR, Meyerson M, Garraway LA.

    Nat Genet. 2007 Mar;39(3):347-51. Epub 2007 Feb 11. Erratum in: Nat Genet. 2007 Apr;39(4):567. Macconnaill, Laura E [corrected to MacConaill, Laura]. PMID: 17293865 [PubMed - indexed for MEDLINE]Related articles

    11.

    The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.

    Florez JC, Saxena R, Winckler W, Burtt NP, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Ardlie KG, Daly MJ, Altshuler D, Hirschhorn JN, Groop L.

    Diabetes. 2006 Dec;55(12):3620-4.PMID: 17130512 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity.

    Lyon HN, Florez JC, Bersaglieri T, Saxena R, Winckler W, Almgren P, Lindblad U, Tuomi T, Gaudet D, Zhu X, Cooper R, Ardlie KG, Daly MJ, Altshuler D, Groop L, Hirschhorn JN.

    Diabetes. 2006 Nov;55(11):3180-4.PMID: 17065359 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Common variants in HNF-1 alpha and risk of type 2 diabetes.

    Holmkvist J, Cervin C, Lyssenko V, Winckler W, Anevski D, Cilio C, Almgren P, Berglund G, Nilsson P, Tuomi T, Lindgren CM, Altshuler D, Groop L.

    Diabetologia. 2006 Dec;49(12):2882-91. Epub 2006 Oct 11.PMID: 17033837 [PubMed - indexed for MEDLINE]Related articles

    14.

    Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes.

    Winckler W, Burtt NP, Holmkvist J, Cervin C, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Altshuler D, Groop L.

    Diabetes. 2005 Aug;54(8):2336-42.PMID: 16046299 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.

    Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Groop L, Altshuler D.

    Diabetes. 2005 Mar;54(3):886-92.PMID: 15734869 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Comparison of fine-scale recombination rates in humans and chimpanzees.

    Winckler W, Myers SR, Richter DJ, Onofrio RC, McDonald GJ, Bontrop RE, McVean GA, Gabriel SB, Reich D, Donnelly P, Altshuler D.

    Science. 2005 Apr 1;308(5718):107-11. Epub 2005 Feb 10.PMID: 15705809 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Altered pathological progression of diaphragm and quadriceps muscle in TNF-deficient, dystrophin-deficient mice.

    Spencer MJ, Marino MW, Winckler WM.

    Neuromuscul Disord. 2000 Dec;10(8):612-9.PMID: 11053690 [PubMed - indexed for MEDLINE]Related articles

    18.

    Isolation and characterization of five new soluble placental tissue proteins (PP22, PP23, PP24, PP25, PP26).

    Bohn H, Winckler W.

    Arch Gynecol Obstet. 1991;248(3):111-5.PMID: 2018407 [PubMed - indexed for MEDLINE]Related articles

    19.

    Isolation and characterization of membrane-associated placental proteins.

    Bohn H, Winckler W.

    Arch Gynecol Obstet. 1991;248(4):191-8.PMID: 1910322 [PubMed - indexed for MEDLINE]Related articles

    20.

    Immunochemically detected placental proteins and their biological functions.

    Bohn H, Winckler W, Grundmann U.

    Arch Gynecol Obstet. 1991;249(3):107-18. Review.PMID: 1772263 [PubMed - indexed for MEDLINE]Related articles

    21.

    Isolation and characterization of a flavin-containing placental protein (PP3).

    Bohn H, Winckler W.

    Arch Gynecol. 1987;240(4):201-6.PMID: 3606218 [PubMed - indexed for MEDLINE]Related articles

    22.

    Isolation and characterization of four new placental tissue proteins (PP18, PP19, PP20, PP21).

    Bohn H, Winckler W.

    Arch Gynecol. 1985;236(4):235-42.PMID: 3896163 [PubMed - indexed for MEDLINE]Related articles

    23.

    Isolation and characterization of two membrane-associated placental tissue proteins.

    Bohn H, Kraus W, Winckler W.

    Arch Gynecol. 1985;236(4):225-33.PMID: 3896162 [PubMed - indexed for MEDLINE]Related articles

    24.

    Purification and characterization of two new soluble placental tissue proteins (PP13 and PP17).

    Bohn H, Kraus W, Winckler W.

    Oncodev Biol Med. 1983;4(5):343-50.PMID: 6856484 [PubMed - indexed for MEDLINE]Related articles

    25.

    New soluble placental tissue proteins: their isolation, characterization, localization and quantification.

    Bohn H, Kraus W, Winckler W.

    Placenta Suppl. 1982;4:67-81. No abstract available. PMID: 6085895 [PubMed - indexed for MEDLINE]Related articles

    26.

    [Isolation and characterization of a new placental tissue protein (PP11) (author's transl)]

    Bohn H, Winckler W.

    Arch Gynecol. 1980;229(4):293-301. German. No abstract available. PMID: 7416809 [PubMed - indexed for MEDLINE]Related articles

    27.

    [Isolation and characterization of the placental protein pp5 (author's transl)]

    Bohn H, Winckler W.

    Arch Gynakol. 1977 Oct 28;223(3):179-86. German. PMID: 579296 [PubMed - indexed for MEDLINE]Related articles

    28.

    [Isolation, characterization and quantitative immunochemical determination of two new serum proteins HPG-1 and HPG-2 (author's transl)]

    Bohn H, Winckler W.

    Blut. 1977 Sep 18;35(4):305-15. German. No abstract available. PMID: 912111 [PubMed - indexed for MEDLINE]Related articles

    29.

    [Isolation and characterization of a new tissue protein (pp7) from human placentae (author's transl)]

    Bohn H, Winckler W.

    Arch Gynakol. 1977 Jan 27;222(1):5-13. German. PMID: 576386 [PubMed - indexed for MEDLINE]Related articles

    30.

    [Isolation and characterization of pregnancy associated alpha2 glycoprotein]

    Bohn H, Winckler W.

    Blut. 1976 Dec;33(6):377-88. German. PMID: 63301 [PubMed - indexed for MEDLINE]Related articles

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