PubMed

Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211.

Su Z, Gulick RM, Krambrink A, Coakley E, Hughes MD, Han D, Flexner C, Wilkin TJ, Skolnik PR, Greaves WL, Kuritzkes DR, Reeves JD; AIDS Clinical Trials Group A5211 Team.

J Infect Dis. 2009 Dec 1;200(11):1724-8.PMID: 19874179 [PubMed - in process]Related articles

The accelerator hypothesis: a review of the evidence for insulin resistance as the basis for type I as well as type II diabetes.

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Assortative weight gain in mother-daughter and father-son pairs: an emerging source of childhood obesity. Longitudinal study of trios (EarlyBird 43).

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Int J Obes (Lond). 2009 Jul;33(7):727-35. Epub 2009 May 12.PMID: 19434065 [PubMed - in process]Related articles

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Chronic fatigue: is it endocrinology?

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Glucose allostasis: emperor's new clothes?

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Diabetologia. 2009 May;52(5):776-8. Epub 2009 Feb 19. No abstract available. PMID: 19225752 [PubMed - indexed for MEDLINE]Related articles

Lymphoma diagnosis and plasma Epstein-Barr virus load during vicriviroc therapy: results of the AIDS Clinical Trials Group A5211.

Tsibris AM, Paredes R, Chadburn A, Su Z, Henrich TJ, Krambrink A, Hughes MD, Aberg JA, Currier JS, Tashima K, Godfrey C, Greaves W, Flexner C, Skolnik PR, Wilkin TJ, Gulick RM, Kuritzkes DR.

Clin Infect Dis. 2009 Mar 1;48(5):642-9.PMID: 19191652 [PubMed - indexed for MEDLINE]Related articlesFree article

Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes.

Wilkin TJ, McKinnon JE, DiRienzo AG, Mollan K, Fletcher CV, Margolis DM, Bastow B, Thal G, Woodward W, Godfrey C, Wiegand A, Maldarelli F, Palmer S, Coffin JM, Mellors JW, Swindells S.

J Infect Dis. 2009 Mar 15;199(6):866-71.PMID: 19191590 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of early weight gain to childhood overweight and metabolic health: a longitudinal study (EarlyBird 36).

Gardner DS, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ.

Pediatrics. 2009 Jan;123(1):e67-73.PMID: 19117849 [PubMed - indexed for MEDLINE]Related articles

Adiponectin in childhood.

Jeffery AN, Murphy MJ, Metcalf BS, Hosking J, Voss LD, English P, Sattar N, Wilkin TJ.

Int J Pediatr Obes. 2008;3(3):130-40. Review.PMID: 19086185 [PubMed - indexed for MEDLINE]Related articles

Objectively measured physical activity and its association with adiponectin and other novel metabolic markers: a longitudinal study in children (EarlyBird 38).

Metcalf BS, Jeffery AN, Hosking J, Voss LD, Sattar N, Wilkin TJ.

Diabetes Care. 2009 Mar;32(3):468-73. Epub 2008 Nov 25.PMID: 19033408 [PubMed - indexed for MEDLINE]Related articlesFree article

When to start antiretroviral therapy?

Wilkin TJ, Gulick RM.

Clin Infect Dis. 2008 Dec 15;47(12):1580-6. Review.PMID: 18990069 [PubMed - indexed for MEDLINE]Related articles

Adiponectin in childhood.

Jeffery AN, Murphy MJ, Metcalf BS, Hosking J, Voss LD, English P, Sattar N, Wilkin TJ.

Int J Pediatr Obes. 2008 Mar 6:1-11. [Epub ahead of print]PMID: 18608628 [PubMed - as supplied by publisher]Related articles

Physical activity at the government-recommended level and obesity-related health outcomes: a longitudinal study (Early Bird 37).

Metcalf BS, Voss LD, Hosking J, Jeffery AN, Wilkin TJ.

Arch Dis Child. 2008 Sep;93(9):772-7. Epub 2008 Jun 30.PMID: 18591181 [PubMed - indexed for MEDLINE]Related articles

Diabetes: 1 and 2, or one and the same? Progress with the accelerator hypothesis.

Wilkin TJ.

Pediatr Diabetes. 2008 Jun;9(3 Pt 2):23-32. Review.PMID: 18540866 [PubMed - indexed for MEDLINE]Related articles

Distribution of adiponectin, leptin, and metabolic correlates of insulin resistance: a longitudinal study in British children; 1: Prepuberty (EarlyBird 15).

Murphy MJ, Hosking J, Metcalf BS, Voss LD, Jeffery AN, Sattar N, Williams R, Jeffery J, Wilkin TJ.

Clin Chem. 2008 Aug;54(8):1298-306. Epub 2008 Jun 6.PMID: 18539644 [PubMed - indexed for MEDLINE]Related articlesFree article

Children from low-income families have less access to sports facilities, but are no less physically active: cross-sectional study (EarlyBird 35).

Voss LD, Hosking J, Metcalf BS, Jeffery AN, Wilkin TJ.

Child Care Health Dev. 2008 Jul;34(4):470-4. Epub 2008 May 15.PMID: 18485026 [PubMed - indexed for MEDLINE]Related articles

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Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers.

Srirangalingam U, Walker L, Khoo B, MacDonald F, Gardner D, Wilkin TJ, Skelly RH, George E, Spooner D, Monson JP, Grossman AB, Akker SA, Pollard PJ, Plowman N, Avril N, Berney DM, Burrin JM, Reznek RH, Kumar VK, Maher ER, Chew SL.

Clin Endocrinol (Oxf). 2008 Oct;69(4):587-96. Epub 2008 Apr 14.PMID: 18419787 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and progression to type 1 diabetes in the European Nicotinamide Diabetes Intervention Trial (ENDIT): response to Bingley et al.

Wilkin TJ.

Diabetes Care. 2008 Apr;31(4):e29. No abstract available. PMID: 18375430 [PubMed - indexed for MEDLINE]Related articlesFree article

Trends, associations and predictions of insulin resistance in prepubertal children (EarlyBird 29).

Gardner DS, Metcalf BS, Hosking J, Jeffery AN, Voss LD, Wilkin TJ.

Pediatr Diabetes. 2008 Jun;9(3 Pt 1):214-20. Epub 2008 Mar 5.PMID: 18331409 [PubMed - indexed for MEDLINE]Related articles

Comment on: Gale EAM (2007) To boldly go -- or to go too boldly? The accelerator hypothesis revisited. Diabetologia 50:1571-1575 -- a reply to the editor.

Wilkin TJ.

Diabetologia. 2007 Dec;50(12):2604-6. Epub 2007 Oct 5. No abstract available. PMID: 17917712 [PubMed - indexed for MEDLINE]Related articles

Potential risks and benefits of HIV treatment simplification: a simulation model of a proposed clinical trial.

Schackman BR, Scott CA, Sax PE, Losina E, Wilkin TJ, McKinnon JE, Swindells S, Weinstein MC, Freedberg KA.

Clin Infect Dis. 2007 Oct 15;45(8):1062-70. Epub 2007 Sep 4.PMID: 17879926 [PubMed - indexed for MEDLINE]Related articlesFree article

Resting energy expenditure, adiponectin and changes in body composition of young children (EarlyBird 34).

Hosking J, Metcalf BS, Jeffery AN, Gardner D, Voss LD, Wilkin TJ.

Int J Pediatr Obes. 2007 Aug 29:1-6. [Epub ahead of print]PMID: 17852541 [PubMed - as supplied by publisher]Related articles

Behavior of insulin resistance and its metabolic correlates in prepubertal children: a longitudinal study (EarlyBird 32).

Jeffery AN, Alba S, Murphy MJ, Voss LD, Metcalf BS, Hosking J, Gardner DS, Sattar N, Wilkin TJ.

Diabetes Care. 2007 Nov;30(11):2962-4. Epub 2007 Aug 21. No abstract available. PMID: 17712029 [PubMed - indexed for MEDLINE]Related articlesFree article

The accelerator hypothesis cannot be tested using the type 2 diabetes gene, TCF7L2.

Wilkin TJ.

Diabetologia. 2007 Aug;50(8):1780. Epub 2007 Jun 23. No abstract available. PMID: 17589824 [PubMed - indexed for MEDLINE]Related articles

Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211.

Gulick RM, Su Z, Flexner C, Hughes MD, Skolnik PR, Wilkin TJ, Gross R, Krambrink A, Coakley E, Greaves WL, Zolopa A, Reichman R, Godfrey C, Hirsch M, Kuritzkes DR; AIDS Clinical Trials Group 5211 Team.

J Infect Dis. 2007 Jul 15;196(2):304-12. Epub 2007 Jun 5.PMID: 17570119 [PubMed - indexed for MEDLINE]Related articles

Advances in antiretroviral therapy.

Jones J, Taylor B, Wilkin TJ, Hammer SM.

Top HIV Med. 2007 Apr-May;15(2):48-82.PMID: 17485787 [PubMed - indexed for MEDLINE]Related articlesFree article

Changing perspectives in diabetes: their impact on its classification.

Wilkin TJ.

Diabetologia. 2007 Aug;50(8):1587-92. Epub 2007 Apr 25.PMID: 17457564 [PubMed - indexed for MEDLINE]Related articles

HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211.

Wilkin TJ, Su Z, Kuritzkes DR, Hughes M, Flexner C, Gross R, Coakley E, Greaves W, Godfrey C, Skolnik PR, Timpone J, Rodriguez B, Gulick RM.

Clin Infect Dis. 2007 Feb 15;44(4):591-5. Epub 2007 Jan 17. Erratum in: Clin Infect Dis. 2007 May 15;44(10):1399. PMID: 17243065 [PubMed - indexed for MEDLINE]Related articles

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.

Weedon MN, Clark VJ, Qian Y, Ben-Shlomo Y, Timpson N, Ebrahim S, Lawlor DA, Pembrey ME, Ring S, Wilkin TJ, Voss LD, Jeffery AN, Metcalf B, Ferrucci L, Corsi AM, Murray A, Melzer D, Knight B, Shields B, Smith GD, Hattersley AT, Di Rienzo A, Frayling TM.

Am J Hum Genet. 2006 Dec;79(6):991-1001. Epub 2006 Oct 6.PMID: 17186458 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of foot-to-foot bioelectrical impedance analysis with dual-energy X-ray absorptiometry in the assessment of body composition in young children: the EarlyBird cohort.

Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ.

Br J Nutr. 2006 Dec;96(6):1163-8.PMID: 17181893 [PubMed - indexed for MEDLINE]Related articles

Postpartum multifocal avascular necrosis: what are the possible etiologies?

Brown ME, Hickling P, Wilkin TJ.

J Clin Rheumatol. 2001 Feb;7(1):38-41.PMID: 17039087 [PubMed]Related articles

Triglyceride associated polymorphisms of the APOA5 gene have very different allele frequencies in Pune, India compared to Europeans.

Chandak GR, Ward KJ, Yajnik CS, Pandit AN, Bavdekar A, Joglekar CV, Fall CH, Mohankrishna P, Wilkin TJ, Metcalf BS, Weedon MN, Frayling TM, Hattersley AT.

BMC Med Genet. 2006 Oct 10;7:76.PMID: 17032446 [PubMed - indexed for MEDLINE]Related articlesFree article

Little evidence for early programming of weight and insulin resistance for contemporary children: EarlyBird Diabetes Study report 19.

Jeffery AN, Metcalf BS, Hosking J, Murphy MJ, Voss LD, Wilkin TJ.

Pediatrics. 2006 Sep;118(3):1118-23.PMID: 16951006 [PubMed - indexed for MEDLINE]Related articlesFree article

Does lean rather than fat mass provide the link between birth weight, BMI, and metabolic risk? EarlyBird 23.

Murphy MJ, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ.

Pediatr Diabetes. 2006 Aug;7(4):211-4.PMID: 16911008 [PubMed - indexed for MEDLINE]Related articles

The accelerator hypothesis: a unifying explanation for type-1 and type-2 diabetes.

Wilkin TJ.

Nestle Nutr Workshop Ser Clin Perform Programme. 2006;11:139-50; discussion 150-3. Review.PMID: 16820737 [PubMed - indexed for MEDLINE]Related articles

The gender insulin hypothesis: why girls are born lighter than boys, and the implications for insulin resistance.

Wilkin TJ, Murphy MJ.

Int J Obes (Lond). 2006 Jul;30(7):1056-61. Review.PMID: 16801943 [PubMed - indexed for MEDLINE]Related articles

Variation in physical activity lies with the child, not his environment: evidence for an 'activitystat' in young children (EarlyBird 16).

Wilkin TJ, Mallam KM, Metcalf BS, Jeffery AN, Voss LD.

Int J Obes (Lond). 2006 Jul;30(7):1050-5.PMID: 16801942 [PubMed - indexed for MEDLINE]Related articles

Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes: response to Dabelea et al.

Wilkin TJ.

Diabetes Care. 2006 Jun;29(6):1462-3; author reply 1463-4. No abstract available. PMID: 16732053 [PubMed - indexed for MEDLINE]Related articlesFree article

The great weight gain experiment, accelerators, and their implications for autoantibodies in diabetes.

Wilkin TJ.

Arch Dis Child. 2006 Jun;91(6):456-8. No abstract available. PMID: 16714715 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased urinary dopamine excretion in association with bilateral carotid body tumours-- clinical, biochemical and genetic findings.

Jeffery J, Devendra D, Farrugia J, Gardner D, Murphy MJ, Williams R, Ayling RM, Wilkin TJ.

Ann Clin Biochem. 2006 Mar;43(Pt 2):156-60.PMID: 16536919 [PubMed - indexed for MEDLINE]Related articles

IOTF thresholds for overweight and obesity and their relation to metabolic risk in children (EarlyBird 20).

Voss LD, Metcalf BS, Jeffery AN, Wilkin TJ.

Int J Obes (Lond). 2006 Apr;30(4):606-9.PMID: 16314873 [PubMed - indexed for MEDLINE]Related articles

Antiretroviral therapy: when and what to start-- an American perspective.

Wilkin TJ, Gulick RM.

Curr HIV/AIDS Rep. 2004 Jun;1(2):59-67. Review.PMID: 16091224 [PubMed - indexed for MEDLINE]Related articles

Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.

Franke B, Galloway TS, Wilkin TJ.

Diabetes Metab Res Rev. 2005 Sep-Oct;21(5):395-415. Review.PMID: 15895384 [PubMed - indexed for MEDLINE]Related articles

Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene.

Weedon MN, Frayling TM, Shields B, Knight B, Turner T, Metcalf BS, Voss L, Wilkin TJ, McCarthy A, Ben-Shlomo Y, Davey Smith G, Ring S, Jones R, Golding J, Byberg L, Mann V, Axelsson T, Syvänen AC, Leon D, Hattersley AT.

Diabetes. 2005 Feb;54(2):576-81.PMID: 15677518 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploring the idiotypes of insulin antibodies as markers for remission in Type 1 diabetes.

Devendra D, Galloway TS, Horton SJ, Wilkin TJ.

Diabet Med. 2004 Dec;21(12):1316-24.PMID: 15569135 [PubMed - indexed for MEDLINE]Related articles

Parents' awareness of overweight in themselves and their children: cross sectional study within a cohort (EarlyBird 21).

Jeffery AN, Voss LD, Metcalf BS, Alba S, Wilkin TJ.

BMJ. 2005 Jan 1;330(7481):23-4. Epub 2004 Nov 26. No abstract available. PMID: 15567804 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic risk in early childhood: the EarlyBird Study.

Wilkin TJ, Voss LD, Metcalf BS, Mallam K, Jeffery AN, Alba S, Murphy MJ.

Int J Obes Relat Metab Disord. 2004 Nov;28 Suppl 3:S64-9.PMID: 15543222 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome: maladaptation to a modern world.

Wilkin TJ, Voss LD.

J R Soc Med. 2004 Nov;97(11):511-20. Review. No abstract available. PMID: 15520144 [PubMed - indexed for MEDLINE]Related articlesFree article