PubMed

Differences in Genetic Background Between Active Smokers, Passive Smokers, and Non-Smokers With Crohn's Disease.

van der Heide F, Nolte IM, Kleibeuker JH, Wijmenga C, Dijkstra G, Weersma RK.

Am J Gastroenterol. 2009 Dec 1. [Epub ahead of print]PMID: 19953089 [PubMed - as supplied by publisher]Related articles

Genome-wide association analysis in primary sclerosing cholangitis.

Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma R, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns M, Schrumpf E, Boberg KM, Schreiber S.

Gastroenterology. 2009 Nov 25. [Epub ahead of print]PMID: 19944697 [PubMed - as supplied by publisher]Related articles

Systematic genotype-phenotype analysis of autism susceptibility loci implicates additional symptoms to co-occur with autism.

Buizer-Voskamp JE, Franke L, Staal WG, van Daalen E, Kemner C, Ophoff RA, Vorstman JA, van Engeland H, Wijmenga C.

Eur J Hum Genet. 2009 Nov 25. [Epub ahead of print]PMID: 19935830 [PubMed - as supplied by publisher]Related articles

[In Process Citation]

Wijmenga C, van Haeften TW, Hofker MH.

Ned Tijdschr Geneeskd. 2009;153:A959. Dutch. PMID: 19930746 [PubMed - in process]Related articles

[The genetic basis of inflammatory bowel disease unravelled by genetic association studies]

Visschedijk MC, Festen EA, Wijmenga C, Weersma RK.

Ned Tijdschr Geneeskd. 2009;153:A402. Dutch. PMID: 19900309 [PubMed - in process]Related articles

Human dectin-1 deficiency and mucocutaneous fungal infections.

Ferwerda B, Ferwerda G, Plantinga TS, Willment JA, van Spriel AB, Venselaar H, Elbers CC, Johnson MD, Cambi A, Huysamen C, Jacobs L, Jansen T, Verheijen K, Masthoff L, Morré SA, Vriend G, Williams DL, Perfect JR, Joosten LA, Wijmenga C, van der Meer JW, Adema GJ, Kullberg BJ, Brown GD, Netea MG.

N Engl J Med. 2009 Oct 29;361(18):1760-7.PMID: 19864674 [PubMed - indexed for MEDLINE]Related articles

Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk.

Festen EA, Stokkers PC, van Diemen CC, van Bodegraven AA, Boezen HM, Crusius BJ, Hommes DW, van der Woude JC, Balschun T, Verspaget HW, Schreiber S, de Jong DJ, Franke A, Dijkstra G, Wijmenga C, Weersma RK.

Am J Gastroenterol. 2009 Oct 27. [Epub ahead of print]PMID: 19861958 [PubMed - as supplied by publisher]Related articles

Genes influencing coagulation and the risk of aneurysmal subarachnoid hemorrhage, and subsequent complications of secondary cerebral ischemia and rebleeding.

Ruigrok YM, Slooter AJ, Rinkel GJ, Wijmenga C, Rosendaal FR.

Acta Neurochir (Wien). 2009 Oct 14. [Epub ahead of print]PMID: 19826759 [PubMed - as supplied by publisher]Related articles

COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.

van de Sluis B, Groot AJ, Vermeulen J, van der Wall E, van Diest PJ, Wijmenga C, Klomp LW, Vooijs M.

PLoS One. 2009 Oct 5;4(10):e7332.PMID: 19802386 [PubMed - in process]Related articlesFree article

Type 2 Diabetes Mellitus: New Genetic Insights will Lead to New Therapeutics.

Wolfs MG, Hofker MH, Wijmenga C, van Haeften TW.

Curr Genomics. 2009 Apr;10(2):110-8.PMID: 19794883 [PubMed - in process]Related articlesFree article

Variants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.

Elbers CC, de Kovel CG, van der Schouw YT, Meijboom JR, Bauer F, Grobbee DE, Trynka G, van Vliet-Ostaptchouk JV, Wijmenga C, Onland-Moret NC.

PLoS One. 2009 Sep 17;4(9):e7070.PMID: 19759915 [PubMed - in process]Related articlesFree article

Comment on: Perry et al. (2009) interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach. Diabetes;58:1463-1467.

Elbers CC, van der Schouw YT, Wijmenga C, Onland-Moret NC.

Diabetes. 2009 Sep;58(9):e9; author reply e10. No abstract available. PMID: 19720820 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in the hypothalamic pathways and its role on obesity.

van Vliet-Ostaptchouk JV, Hofker MH, van der Schouw YT, Wijmenga C, Onland-Moret NC.

Obes Rev. 2009 Nov;10(6):593-609. Epub 2009 Jun 5.PMID: 19712437 [PubMed - in process]Related articles

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.

Bauer F, Elbers CC, Adan RA, Loos RJ, Onland-Moret NC, Grobbee DE, van Vliet-Ostaptchouk JV, Wijmenga C, van der Schouw YT.

Am J Clin Nutr. 2009 Oct;90(4):951-9. Epub 2009 Aug 19.PMID: 19692490 [PubMed - indexed for MEDLINE]Related articles

Association of the TGF-beta receptor genes with abdominal aortic aneurysm.

Baas AF, Medic J, van 't Slot R, de Kovel CG, Zhernakova A, Geelkerken RH, Kranendonk SE, van Sterkenburg SM, Grobbee DE, Boll AP, Wijmenga C, Blankensteijn JD, Ruigrok YM.

Eur J Hum Genet. 2009 Aug 12. [Epub ahead of print]PMID: 19672284 [PubMed - as supplied by publisher]Related articles

Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study.

van den Berg SW, Dollé ME, Imholz S, van der A DL, van 't Slot R, Wijmenga C, Verschuren WM, Strien C, Siezen CL, Hoebee B, Feskens EJ, Boer JM.

Int J Obes (Lond). 2009 Oct;33(10):1143-52. Epub 2009 Aug 4.PMID: 19652658 [PubMed - in process]Related articles

Common and different genetic background for rheumatoid arthritis and coeliac disease.

Coenen MJ, Trynka G, Heskamp S, Franke B, van Diemen CC, Smolonska J, van Leeuwen M, Brouwer E, Boezen MH, Postma DS, Platteel M, Zanen P, Lammers JW, Groen HJ, Mali WP, Mulder CJ, Tack GJ, Verbeek WH, Wolters VM, Houwen RH, Mearin ML, van Heel DA, Radstake TR, van Riel PL, Wijmenga C, Barrera P, Zhernakova A.

Hum Mol Genet. 2009 Nov 1;18(21):4195-203. Epub 2009 Jul 31.PMID: 19648290 [PubMed - in process]Related articles

Meta-analysis of genome-wide linkage studies in celiac disease.

Forabosco P, Neuhausen SL, Greco L, Naluai AT, Wijmenga C, Saavalainen P, Houlston RS, Ciclitira PJ, Babron MC, Lewis CM.

Hum Hered. 2009;68(4):223-30. Epub 2009 Jul 22.PMID: 19622889 [PubMed - in process]Related articles

Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research.

Smolonska J, Wijmenga C, Postma DS, Boezen HM.

Am J Respir Crit Care Med. 2009 Oct 1;180(7):618-31. Epub 2009 Jul 16. Review.PMID: 19608716 [PubMed - indexed for MEDLINE]Related articles

Inflammatory bowel disease and celiac disease: overlaps in the pathology and genetics, and their potential drug targets.

Festen EA, Szperl AM, Weersma RK, Wijmenga C, Wapenaar MC.

Endocr Metab Immune Disord Drug Targets. 2009 Jun;9(2):199-218. Review.PMID: 19519468 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene.

Knauff EA, Franke L, van Es MA, van den Berg LH, van der Schouw YT, Laven JS, Lambalk CB, Hoek A, Goverde AJ, Christin-Maitre S, Hsueh AJ, Wijmenga C, Fauser BC; Dutch POF Consortium.

Hum Reprod. 2009 Sep;24(9):2372-8. Epub 2009 Jun 9.PMID: 19508998 [PubMed - indexed for MEDLINE]Related articles

Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.

Ruigrok YM, Rinkel GJ, Wijmenga C, Kasuya H, Tajima A, Takahashi T, Hata A, Inoue I, Krischek B.

Cerebrovasc Dis. 2009;28(2):131-4. Epub 2009 Jun 5.PMID: 19506372 [PubMed - indexed for MEDLINE]Related articles

Gene-network analysis identifies susceptibility genes related to glycobiology in autism.

van der Zwaag B, Franke L, Poot M, Hochstenbach R, Spierenburg HA, Vorstman JA, van Daalen E, de Jonge MV, Verbeek NE, Brilstra EH, van 't Slot R, Ophoff RA, van Es MA, Blauw HM, Veldink JH, Buizer-Voskamp JE, Beemer FA, van den Berg LH, Wijmenga C, van Amstel HK, van Engeland H, Burbach JP, Staal WG.

PLoS One. 2009 May 28;4(5):e5324.PMID: 19492091 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease.

Romanos J, van Diemen CC, Nolte IM, Trynka G, Zhernakova A, Fu J, Bardella MT, Barisani D, McManus R, van Heel DA, Wijmenga C.

Gastroenterology. 2009 Sep;137(3):834-40, 840.e1-3. Epub 2009 May 18.PMID: 19454285 [PubMed - indexed for MEDLINE]Related articles

The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

Kurreeman FA, Goulielmos GN, Alizadeh BZ, Rueda B, Houwing-Duistermaat J, Sánchez E, Bevova M, Radstake TR, Vonk MC, Galanakis E, Ortego N, Verduyn W, Zervou MI, Consortium S, Roep BO, Dema B, Espino L, Urcelay E, Boumpas DT, van den Berg LH, Wijmenga C, Koeleman BP, Huizinga TW, Toes RE, Martin J.

Ann Rheum Dis. 2009 May 18. [Epub ahead of print]PMID: 19433411 [PubMed - as supplied by publisher]Related articles

Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.

Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R.

Pediatr Infect Dis J. 2009 Apr;28(4):333-5.PMID: 19258923 [PubMed - indexed for MEDLINE]Related articles

Cost-effective HLA typing with tagging SNPs predicts celiac disease risk haplotypes in the Finnish, Hungarian, and Italian populations.

Koskinen L, Romanos J, Kaukinen K, Mustalahti K, Korponay-Szabo I, Barisani D, Bardella MT, Ziberna F, Vatta S, Széles G, Pocsai Z, Karell K, Haimila K, Adány R, Not T, Ventura A, Mäki M, Partanen J, Wijmenga C, Saavalainen P.

Immunogenetics. 2009 Apr;61(4):247-56. Epub 2009 Mar 3.PMID: 19255754 [PubMed - indexed for MEDLINE]Related articles

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C.

Gut. 2009 Aug;58(8):1078-83. Epub 2009 Feb 24.PMID: 19240061 [PubMed - indexed for MEDLINE]Related articles

Using genome-wide pathway analysis to unravel the etiology of complex diseases.

Elbers CC, van Eijk KR, Franke L, Mulder F, van der Schouw YT, Wijmenga C, Onland-Moret NC.

Genet Epidemiol. 2009 Jul;33(5):419-31.PMID: 19235186 [PubMed - indexed for MEDLINE]Related articles

Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity.

Muller PA, van de Sluis B, Groot AJ, Verbeek D, Vonk WI, Maine GN, Burstein E, Wijmenga C, Vooijs M, Reits E, Klomp LW.

Traffic. 2009 Feb 11. [Epub ahead of print]PMID: 19220812 [PubMed - as supplied by publisher]Related articles

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD.

Gut. 2009 Jun;58(6):799-804. Epub 2009 Feb 6.PMID: 19201773 [PubMed - indexed for MEDLINE]Related articles

Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea.

Heinz-Erian P, Müller T, Krabichler B, Schranz M, Becker C, Rüschendorf F, Nürnberg P, Rossier B, Vujic M, Booth IW, Holmberg C, Wijmenga C, Grigelioniene G, Kneepkens CM, Rosipal S, Mistrik M, Kappler M, Michaud L, Dóczy LC, Siu VM, Krantz M, Zoller H, Utermann G, Janecke AR.

Am J Hum Genet. 2009 Feb;84(2):188-96. Epub 2009 Jan 29.PMID: 19185281 [PubMed - indexed for MEDLINE]Related articlesFree article

A supersized list of obesity genes.

Hofker M, Wijmenga C.

Nat Genet. 2009 Feb;41(2):139-40. No abstract available. PMID: 19174833 [PubMed - indexed for MEDLINE]Related articles

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.

Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, Schreiber S, Dijkstra G, Franke A, Nolte IM, Rutgeerts P, Wijmenga C, Vermeire S.

Am J Gastroenterol. 2009 Mar;104(3):630-8. Epub 2009 Jan 27.PMID: 19174780 [PubMed - indexed for MEDLINE]Related articles

Complex nature of SNP genotype effects on gene expression in primary human leucocytes.

Heap GA, Trynka G, Jansen RC, Bruinenberg M, Swertz MA, Dinesen LC, Hunt KA, Wijmenga C, Vanheel DA, Franke L.

BMC Med Genomics. 2009 Jan 7;2:1.PMID: 19128478 [PubMed - in process]Related articlesFree article

Comment on: Barker et al. (2008) Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: Diabetes 57:3152-3155, 2008.

Romanos J, Wijmenga C.

Diabetes. 2009 Jan;58(1):e1; author reply e2. No abstract available. PMID: 19114716 [PubMed - indexed for MEDLINE]Related articlesFree article

Association study of the IL18RAP locus in three European populations with coeliac disease.

Koskinen LL, Einarsdottir E, Dukes E, Heap GA, Dubois P, Korponay-Szabo IR, Kaukinen K, Kurppa K, Ziberna F, Vatta S, Not T, Ventura A, Sistonen P, Adány R, Pocsai Z, Széles G, Mäki M, Kere J, Wijmenga C, van Heel DA, Saavalainen P.

Hum Mol Genet. 2009 Mar 15;18(6):1148-55. Epub 2008 Dec 22.PMID: 19103669 [PubMed - indexed for MEDLINE]Related articles

Detecting shared pathogenesis from the shared genetics of immune-related diseases.

Zhernakova A, van Diemen CC, Wijmenga C.

Nat Rev Genet. 2009 Jan;10(1):43-55. Review.PMID: 19092835 [PubMed - indexed for MEDLINE]Related articles

Using genetic information for the identification, classification and treatment of Crohn's disease: are we there yet?

Weersma RK, Wijmenga C.

Expert Rev Gastroenterol Hepatol. 2008 Dec;2(6):719-21. No abstract available. PMID: 19090731 [PubMed - indexed for MEDLINE]Related articles

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA.

N Engl J Med. 2008 Dec 25;359(26):2767-77. Epub 2008 Dec 10.PMID: 19073967 [PubMed - indexed for MEDLINE]Related articlesFree article

Susceptibility loci for intracranial aneurysm in European and Japanese populations.

Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Fraunberg M, van Duijn CM, van den Berg LH, Mane S, Mason CE, Choi M, Gaál E, Bayri Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, Tajima A, Laakso A, Hata A, Kasuya H, Koivisto T, Rinne J, Ohman J, Breteler MM, Wijmenga C, State MW, Rinkel GJ, Hernesniemi J, Jääskeläinen JE, Palotie A, Inoue I, Lifton RP, Günel M.

Nat Genet. 2008 Dec;40(12):1472-7. Epub 2008 Nov 9.PMID: 18997786 [PubMed - indexed for MEDLINE]Related articlesFree article

Male-specific association between a gamma-secretase polymorphism and premature coronary atherosclerosis.

van Loo KM, Dejaegere T, van Zweeden M, van Schijndel JE, Wijmenga C, Trip MD, Martens GJ.

PLoS One. 2008;3(11):e3662. Epub 2008 Nov 6.PMID: 18987747 [PubMed - indexed for MEDLINE]Related articlesFree article

No association of PTPN1 polymorphisms with macronutrient intake and measures of adiposity.

Bauer F, Onland-Moret NC, Niehoff AG, Elbers CC, Grobbee DE, Wijmenga C, van der Schouw YT.

Obesity (Silver Spring). 2008 Dec;16(12):2767-71. Epub 2008 Oct 9.PMID: 18846048 [PubMed - indexed for MEDLINE]Related articles

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.

Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH; IBSEN study group, Mathew CG, Schreiber S.

Nat Genet. 2008 Nov;40(11):1319-23. Epub 2008 Oct 5.PMID: 18836448 [PubMed - indexed for MEDLINE]Related articles

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort.

Weersma RK, Stokkers PC, van Bodegraven AA, van Hogezand RA, Verspaget HW, de Jong DJ, van der Woude CJ, Oldenburg B, Linskens RK, Festen EA, van der Steege G, Hommes DW, Crusius JB, Wijmenga C, Nolte IM, Dijkstra G; Dutch Initiative on Crohn and Colitis (ICC).

Gut. 2009 Mar;58(3):388-95. Epub 2008 Sep 29.PMID: 18824555 [PubMed - indexed for MEDLINE]Related articles

Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease.

Romanos J, Barisani D, Trynka G, Zhernakova A, Bardella MT, Wijmenga C.

J Med Genet. 2009 Jan;46(1):60-3. Epub 2008 Sep 19.PMID: 18805825 [PubMed - indexed for MEDLINE]Related articles

Relevance of animal models for understanding mammalian copper homeostasis.

Vonk WI, Wijmenga C, van de Sluis B.

Am J Clin Nutr. 2008 Sep;88(3):840S-5S. Review.PMID: 18779305 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

Lu Y, Dollé ME, Imholz S, van 't Slot R, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM.

J Lipid Res. 2008 Dec;49(12):2582-9. Epub 2008 Jul 25.PMID: 18660489 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of STAT4 with rheumatoid arthritis: a replication study in three European populations.

Orozco G, Alizadeh BZ, Delgado-Vega AM, González-Gay MA, Balsa A, Pascual-Salcedo D, Fernández-Gutierrez B, González-Escribano MF, Petersson IF, van Riel PL, Barrera P, Coenen MJ, Radstake TR, van Leeuwen MA, Wijmenga C, Koeleman BP, Alarcón-Riquelme M, Martín J.

Arthritis Rheum. 2008 Jul;58(7):1974-80.PMID: 18576336 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of DLG5 variants with gluten-sensitive enteropathy.

Festen EA, Zhernakova A, Wijmenga C, Weersma RK.

Gut. 2008 Jul;57(7):1027-8. No abstract available. PMID: 18559397 [PubMed - indexed for MEDLINE]Related articles