PubMed

Mining incretin hormone pathways for novel therapies.

Wideman RD, Kieffer TJ.

Trends Endocrinol Metab. 2009 Aug;20(6):280-6. Review.PMID: 19595611 [PubMed - indexed for MEDLINE]Related articles

Treatment of diabetes by transplantation of drug-inducible insulin-producing gut cells.

Unniappan S, Wideman RD, Donald C, Gunn V, Wall JL, Zhang QX, Webber TD, Cheung AT, Kieffer TJ.

J Mol Med. 2009 Jul;87(7):703-12. Epub 2009 Apr 23.PMID: 19387601 [PubMed - indexed for MEDLINE]Related articles

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.

Fujita Y, Wideman RD, Speck M, Asadi A, King DS, Webber TD, Haneda M, Kieffer TJ.

Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E473-9. Epub 2008 Dec 23.PMID: 19106249 [PubMed - indexed for MEDLINE]Related articles

Transplantation of PC1/3-Expressing alpha-cells improves glucose handling and cold tolerance in leptin-resistant mice.

Wideman RD, Gray SL, Covey SD, Webb GC, Kieffer TJ.

Mol Ther. 2009 Jan;17(1):191-8. Epub 2008 Oct 21.PMID: 18941442 [PubMed - indexed for MEDLINE]Related articles

A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.

Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ.

Diabetes. 2007 Nov;56(11):2744-52. Epub 2007 Aug 13.PMID: 17698597 [PubMed - indexed for MEDLINE]Related articlesFree article

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

Covey SD, Wideman RD, McDonald C, Unniappan S, Huynh F, Asadi A, Speck M, Webber T, Chua SC, Kieffer TJ.

Cell Metab. 2006 Oct;4(4):291-302.PMID: 17011502 [PubMed - indexed for MEDLINE]Related articles

Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1).

Wideman RD, Yu IL, Webber TD, Verchere CB, Johnson JD, Cheung AT, Kieffer TJ.

Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13468-73. Epub 2006 Aug 28.PMID: 16938896 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate.

Wideman RD, Kieffer TJ.

Horm Metab Res. 2004 Nov-Dec;36(11-12):782-6. Review.PMID: 15655709 [PubMed - indexed for MEDLINE]Related articles

Thermodynamics of denaturation of hisactophilin, a beta-trefoil protein.

Liu C, Chu D, Wideman RD, Houliston RS, Wong HJ, Meiering EM.

Biochemistry. 2001 Apr 3;40(13):3817-27.PMID: 11300762 [PubMed - indexed for MEDLINE]Related articles