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Increased glucocorticoid receptor expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic syndrome.
Whorwood CB, Donovan SJ, Flanagan D, Phillips DI, Byrne CD.
Diabetes. 2002 Apr;51(4):1066-75.PMID: 11916927 [PubMed - indexed for MEDLINE]Related articlesFree article
Maternal undernutrition during early to midgestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11beta-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin ii receptor in neonatal sheep.
Whorwood CB, Firth KM, Budge H, Symonds ME.
Endocrinology. 2001 Jul;142(7):2854-64.PMID: 11416004 [PubMed - indexed for MEDLINE]Related articlesFree article
The maternal diet during pregnancy programs altered expression of the glucocorticoid receptor and type 2 11beta-hydroxysteroid dehydrogenase: potential molecular mechanisms underlying the programming of hypertension in utero.
Bertram C, Trowern AR, Copin N, Jackson AA, Whorwood CB.
Endocrinology. 2001 Jul;142(7):2841-53.PMID: 11416003 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of glucocorticoid receptor alpha and beta isoforms and type I 11beta-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance?
Whorwood CB, Donovan SJ, Wood PJ, Phillips DI.
J Clin Endocrinol Metab. 2001 May;86(5):2296-308.PMID: 11344242 [PubMed - indexed for MEDLINE]Related articlesFree article
Elevated plasma cortisol in glucose-intolerant men: differences in responses to glucose and habituation to venepuncture.
Reynolds RM, Walker BR, Syddall HE, Whorwood CB, Wood PJ, Phillips DI.
J Clin Endocrinol Metab. 2001 Mar;86(3):1149-53.PMID: 11238500 [PubMed - indexed for MEDLINE]Related articlesFree article
Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors.
Reynolds RM, Walker BR, Syddall HE, Andrew R, Wood PJ, Whorwood CB, Phillips DI.
J Clin Endocrinol Metab. 2001 Jan;86(1):245-50.PMID: 11232008 [PubMed - indexed for MEDLINE]Related articlesFree article
Low birth weight predicts elevated plasma cortisol concentrations in adults from 3 populations.
Phillips DI, Walker BR, Reynolds RM, Flanagan DE, Wood PJ, Osmond C, Barker DJ, Whorwood CB.
Hypertension. 2000 Jun;35(6):1301-6.PMID: 10856281 [PubMed - indexed for MEDLINE]Related articlesFree article
Reproducibility of the low dose dexamethasone suppression test: comparison between direct plasma and salivary cortisol assays.
Reynolds RM, Bendall HE, Whorwood CB, Wood PJ, Walker BR, Phillips DI.
Clin Endocrinol (Oxf). 1998 Sep;49(3):307-10.PMID: 9861320 [PubMed - indexed for MEDLINE]Related articles
Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome?
Phillips DI, Barker DJ, Fall CH, Seckl JR, Whorwood CB, Wood PJ, Walker BR.
J Clin Endocrinol Metab. 1998 Mar;83(3):757-60. Review.PMID: 9506721 [PubMed - indexed for MEDLINE]Related articlesFree article
Apparent mineralocorticoid excess in a Brazilian kindred: hypertension in the heterozygote state.
Li A, Li KX, Marui S, Krozowski ZS, Batista MC, Whorwood CB, Arnhold IJ, Shackleton CH, Mendonca BB, Stewart PM.
J Hypertens. 1997 Dec;15(12 Pt 1):1397-402.PMID: 9431844 [PubMed - indexed for MEDLINE]Related articles
Ontogeny and sexual dimorphic expression of mouse type 2 11beta-hydroxysteroid dehydrogenase.
Condon J, Ricketts ML, Whorwood CB, Stewart PM.
Mol Cell Endocrinol. 1997 Mar 28;127(2):121-8.PMID: 9099907 [PubMed - indexed for MEDLINE]Related articles
Human hypertension caused by mutations in the 11 beta-hydroxysteroid dehydrogenase gene: a molecular analysis of apparent mineralocorticoid excess.
Whorwood CB, Stewart PM.
J Hypertens Suppl. 1996 Dec;14(5):S19-24.PMID: 9120678 [PubMed - indexed for MEDLINE]Related articles
Adrenal 11 beta-hydroxysteroid dehydrogenase.
Shimojo M, Condon J, Whorwood CB, Stewart PM.
Endocr Res. 1996 Nov;22(4):771-80.PMID: 8969940 [PubMed - indexed for MEDLINE]Related articles
11 beta-Hydroxysteroid dehydrogenase in the rat adrenal.
Shimojo M, Whorwood CB, Stewart PM.
J Mol Endocrinol. 1996 Oct;17(2):121-30.PMID: 8938587 [PubMed - indexed for MEDLINE]Related articles
Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene.
Stewart PM, Krozowski ZS, Gupta A, Milford DV, Howie AJ, Sheppard MC, Whorwood CB.
Lancet. 1996 Jan 13;347(8994):88-91.PMID: 8538347 [PubMed - indexed for MEDLINE]Related articles
Type 2 11 beta-hydroxysteroid dehydrogenase in foetal and adult life.
Stewart PM, Whorwood CB, Mason JI.
J Steroid Biochem Mol Biol. 1995 Dec;55(5-6):465-71.PMID: 8547171 [PubMed - indexed for MEDLINE]Related articles
Basic and acidic fibroblast growth factor increase prolactin mRNA in a dose-dependent and specific manner in GH3 cells.
Mallo F, Wilson E, Whorwood CB, Singh S, Sheppard MC.
Mol Cell Endocrinol. 1995 Oct 30;114(1-2):117-25.PMID: 8674836 [PubMed - indexed for MEDLINE]Related articles
Transcriptional regulation of Na/K-ATPase by corticosteroids, glycyrrhetinic acid and second messenger pathways in rat kidney epithelial cells.
J Mol Endocrinol. 1995 Aug;15(1):93-103.PMID: 8546817 [PubMed - indexed for MEDLINE]Related articles
Detection of human 11 beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts.
Whorwood CB, Mason JI, Ricketts ML, Howie AJ, Stewart PM.
Mol Cell Endocrinol. 1995 Apr 28;110(1-2):R7-12.PMID: 7545619 [PubMed - indexed for MEDLINE]Related articles
Epithelial cell localization of type 2 11 beta-hydroxysteroid dehydrogenase in rat and human colon.
Whorwood CB, Ricketts ML, Stewart PM.
Endocrinology. 1994 Dec;135(6):2533-41. Erratum in: Endocrinology 1995 Apr;136(4):1774. PMID: 7988441 [PubMed - indexed for MEDLINE]Related articles
Regulation of sodium-potassium adenosine triphosphate subunit gene expression by corticosteroids and 11 beta-hydroxysteroid dehydrogenase activity.
Endocrinology. 1994 Sep;135(3):901-10.PMID: 8070385 [PubMed - indexed for MEDLINE]Related articles
11 beta-Hydroxysteroid dehydrogenase activity and corticosteroid hormone action.
Stewart PM, Whorwood CB.
Steroids. 1994 Feb;59(2):90-5.PMID: 8191554 [PubMed - indexed for MEDLINE]Related articles
Steroid hormones and hypertension: the cortisol-cortisone shuttle.
Stewart PM, Whorwood CB, Walker BR.
Steroids. 1993 Dec;58(12):614-20. Review.PMID: 8116018 [PubMed - indexed for MEDLINE]Related articles
Tissue specific effects of thyroid hormone on 11 beta-hydroxysteroid dehydrogenase gene expression.
Whorwood CB, Sheppard MC, Stewart PM.
J Steroid Biochem Mol Biol. 1993 Nov;46(5):539-47.PMID: 8240975 [PubMed - indexed for MEDLINE]Related articles
Licorice inhibits 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action.
Endocrinology. 1993 Jun;132(6):2287-92.PMID: 8504732 [PubMed - indexed for MEDLINE]Related articles
11 beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in the rat colon.
Whorwood CB, Barber PC, Gregory J, Sheppard MC, Stewart PM.
Am J Physiol. 1993 Jun;264(6 Pt 1):E951-7.PMID: 8392808 [PubMed - indexed for MEDLINE]Related articles
11-beta-hydroxysteroid dehydrogenase activity and gene expression in the hypertensive Bianchi-Milan rat.
Stewart PM, Whorwood CB, Valentino R, Burt D, Sheppard MC, Edwards CR.
J Hypertens. 1993 Apr;11(4):349-54.PMID: 8390501 [PubMed - indexed for MEDLINE]Related articles
Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia.
Whorwood CB, Ueshiba H, del Blazo P.
J Steroid Biochem Mol Biol. 1992 Apr;42(2):211-21.PMID: 1314640 [PubMed - indexed for MEDLINE]Related articles
Tissue localization of 11 beta-hydroxysteroid dehydrogenase and its relationship to the glucocorticoid receptor.
Whorwood CB, Franklyn JA, Sheppard MC, Stewart PM.
J Steroid Biochem Mol Biol. 1992 Jan;41(1):21-8.PMID: 1734933 [PubMed - indexed for MEDLINE]Related articles
A possible defect in the inter-conversion between cortisone and cortisol in prepubertal patients with congenital adrenal hyperplasia receiving cortisone acetate therapy.
Whorwood CB, Warne GL.
J Steroid Biochem Mol Biol. 1991 Oct;39(4A):461-70.PMID: 1911435 [PubMed - indexed for MEDLINE]Related articles
Localization of renal 11 beta-dehydrogenase by in situ hybridization: autocrine not paracrine protector of the mineralocorticoid receptor.
Stewart PM, Whorwood CB, Barber P, Gregory J, Monder C, Franklyn JA, Sheppard MC.
Endocrinology. 1991 Apr;128(4):2129-35.PMID: 1848510 [PubMed - indexed for MEDLINE]Related articles
Serum levels of 5-androstene-3 beta,17 beta-diol sulphate, 5 alpha-androstane-3 alpha, 17beta-diol sulphate and glucuronide, in late onset 21-hydroxylase deficiency.
Montalto J, Funder JW, Yong AB, Whorwood CB, Connelly JF.
J Steroid Biochem Mol Biol. 1990 Nov 30;37(4):593-8.PMID: 2177625 [PubMed - indexed for MEDLINE]Related articles
Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency (NC-3BHSD).
Whorwood CB, Montalto J, Sandars SR, Connelly JF.
J Steroid Biochem. 1990 May;35(6):735-9.PMID: 2362435 [PubMed - indexed for MEDLINE]Related articles
Plasma C19 steroid sulphate levels and indices of androgen bioavailability in female pattern androgenic alopecia.
Montalto J, Whorwood CB, Funder JW, Yong AB, Callan A, Davies HE, Connelly JF.
Clin Endocrinol (Oxf). 1990 Jan;32(1):1-12.PMID: 2139595 [PubMed - indexed for MEDLINE]Related articles
Serum androstanediol glucuronide concentrations in normal and hirsute women and patients with thyroid dysfunction.
Scanlon MJ, Whorwood CB, Franks S, Reed MJ, James VH.
Clin Endocrinol (Oxf). 1988 Nov;29(5):529-38.PMID: 3253032 [PubMed - indexed for MEDLINE]Related articles
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