PubMed

Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease.

Kelly DJ, Edgley AJ, Zhang Y, Thai K, Tan SM, Cox AJ, Advani A, Connelly KA, Whiteside CI, Gilbert RE.

Nephrol Dial Transplant. 2009 Jun;24(6):1782-90. Epub 2009 Jan 20.PMID: 19155535 [PubMed - indexed for MEDLINE]Related articles

High glucose activates PKC-zeta and NADPH oxidase through autocrine TGF-beta1 signaling in mesangial cells.

Xia L, Wang H, Munk S, Kwan J, Goldberg HJ, Fantus IG, Whiteside CI.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1705-14. Epub 2008 Sep 24.PMID: 18815221 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C isozymes and their selectivity towards ruboxistaurin.

Tang S, Xiao V, Wei L, Whiteside CI, Kotra LP.

Proteins. 2008 Jul;72(1):447-60.PMID: 18214957 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen species, PKC-beta1, and PKC-zeta mediate high-glucose-induced vascular endothelial growth factor expression in mesangial cells.

Xia L, Wang H, Munk S, Frecker H, Goldberg HJ, Fantus IG, Whiteside CI.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1280-8. Epub 2007 Aug 21.PMID: 17711990 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase Czeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells.

Iakoubov R, Izzo A, Yeung A, Whiteside CI, Brubaker PL.

Endocrinology. 2007 Mar;148(3):1089-98. Epub 2006 Nov 16.PMID: 17110421 [PubMed - indexed for MEDLINE]Related articlesFree article

Upregulation of osteopontin gene expression in diabetic rat proximal tubular cells revealed by microarray profiling.

Hsieh TJ, Chen R, Zhang SL, Liu F, Brezniceanu ML, Whiteside CI, Fantus IG, Ingelfinger JR, Hamet P, Chan JS.

Kidney Int. 2006 Mar;69(6):1005-15.PMID: 16528250 [PubMed - indexed for MEDLINE]Related articles

Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells.

Goldberg HJ, Whiteside CI, Hart GW, Fantus IG.

Endocrinology. 2006 Jan;147(1):222-31. Erratum in: Endocrinology. 2006 Nov;147(11):5490. PMID: 16365142 [PubMed - indexed for MEDLINE]Related articlesFree article

In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species.

Kwan J, Wang H, Munk S, Xia L, Goldberg HJ, Whiteside CI.

Kidney Int. 2005 Dec;68(6):2526-41.PMID: 16316329 [PubMed - indexed for MEDLINE]Related articles

Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression.

Xia L, Wang H, Goldberg HJ, Munk S, Fantus IG, Whiteside CI.

Am J Physiol Renal Physiol. 2006 Feb;290(2):F345-56. Epub 2005 Aug 30.PMID: 16131649 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase C-dependent.

Young TA, Wang H, Munk S, Hammoudi DS, Young DS, Mandelcorn MS, Whiteside CI.

Exp Eye Res. 2005 May;80(5):651-62. Epub 2005 Jan 4.PMID: 15862172 [PubMed - indexed for MEDLINE]Related articles

Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species.

Whiteside CI.

Curr Hypertens Rep. 2005 Apr;7(2):148-54. Review.PMID: 15748541 [PubMed - indexed for MEDLINE]Related articles

High glucose-suppressed endothelin-1 Ca2+ signaling via NADPH oxidase and diacylglycerol-sensitive protein kinase C isozymes in mesangial cells.

Hua H, Munk S, Goldberg H, Fantus IG, Whiteside CI.

J Biol Chem. 2003 Sep 5;278(36):33951-62. Epub 2003 Jun 23.PMID: 12821678 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction.

Hua H, Munk S, Whiteside CI.

Am J Physiol Renal Physiol. 2003 Feb;284(2):F303-12. Epub 2002 Sep 17.PMID: 12388423 [PubMed - indexed for MEDLINE]Related articlesFree article

The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and -delta.

Goldberg HJ, Whiteside CI, Fantus IG.

J Biol Chem. 2002 Sep 13;277(37):33833-41. Epub 2002 Jul 8.PMID: 12105191 [PubMed - indexed for MEDLINE]Related articlesFree article

Mesangial cell protein kinase C isozyme activation in the diabetic milieu.

Whiteside CI, Dlugosz JA.

Am J Physiol Renal Physiol. 2002 Jun;282(6):F975-80. Review.PMID: 11997313 [PubMed - indexed for MEDLINE]Related articlesFree article

Mesangial cell filamentous actin disassembly and hypocontractility in high glucose are mediated by PKC-zeta.

Dlugosz JA, Munk S, Ispanovic E, Goldberg HJ, Whiteside CI.

Am J Physiol Renal Physiol. 2002 Jan;282(1):F151-63.PMID: 11739123 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose-enhanced mesangial cell extracellular signal-regulated protein kinase activation and alpha1(IV) collagen expression in response to endothelin-1: role of specific protein kinase C isozymes.

Hua H, Goldberg HJ, Fantus IG, Whiteside CI.

Diabetes. 2001 Oct;50(10):2376-83.PMID: 11574422 [PubMed - indexed for MEDLINE]Related articlesFree article

Stretch-induced mesangial cell ERK1/ERK2 activation is enhanced in high glucose by decreased dephosphorylation.

Dlugosz JA, Munk S, Kapor-Drezgic J, Goldberg HJ, Fantus IG, Scholey JW, Whiteside CI.

Am J Physiol Renal Physiol. 2000 Oct;279(4):F688-97.PMID: 10997919 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1-induced mesangial cell contraction involves activation of protein kinase C-alpha, -delta, and -epsilon.

Dlugosz JA, Munk S, Zhou X, Whiteside CI.

Am J Physiol. 1998 Sep;275(3 Pt 2):F423-32.PMID: 9729516 [PubMed - indexed for MEDLINE]Related articlesFree article

Preconditioning cultured human pediatric myocytes requires adenosine and protein kinase C.

Ikonomidis JS, Shirai T, Weisel RD, Derylo B, Rao V, Whiteside CI, Mickle DA, Li RK.

Am J Physiol. 1997 Mar;272(3 Pt 2):H1220-30.PMID: 9087596 [PubMed - indexed for MEDLINE]Related articles

Heparin inhibits mitogen-activated protein kinase-dependent and -independent c-fos induction in mesangial cells.

Miralem T, Wang A, Whiteside CI, Templeton DM.

J Biol Chem. 1996 Jul 19;271(29):17100-6.PMID: 8663360 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracellular chloride regulates mesangial cell calcium response to vasopressor peptides.

Stevanovic ZS, Salter MW, Whiteside CI.

Am J Physiol. 1996 Jul;271(1 Pt 2):F21-9.PMID: 8760239 [PubMed - indexed for MEDLINE]Related articles

Collagen type I enhances endothelin-mediated contraction and induces nonproliferating phenotype in mesangial cells.

Miralem T, Whiteside CI, Templeton DM.

Am J Physiol. 1996 Jun;270(6 Pt 2):F960-70.PMID: 8764315 [PubMed - indexed for MEDLINE]Related articles

Glomerular dysfunction in the aging Fischer 344 rat is associated with excessive growth and normal mesangial cell function.

McDermott GF, Ingram A, Scholey J, Kirkland JL, Whiteside CI.

J Gerontol A Biol Sci Med Sci. 1996 Mar;51(2):M80-5.PMID: 8612108 [PubMed - indexed for MEDLINE]Related articles

Prevention of early glomerulopathy with tolrestat in the streptozotocin-induced diabetic rat.

Donnelly SM, Zhou XP, Huang JT, Whiteside CI.

Biochem Cell Biol. 1996;74(3):355-62.PMID: 8883841 [PubMed - indexed for MEDLINE]Related articles

Molecular cloning, expression, and characterization of podocalyxin-like protein 1 from rabbit as a transmembrane protein of glomerular podocytes and vascular endothelium.

Kershaw DB, Thomas PE, Wharram BL, Goyal M, Wiggins JE, Whiteside CI, Wiggins RC.

J Biol Chem. 1995 Dec 8;270(49):29439-46.PMID: 7493982 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose alters actin assembly in glomerular mesangial and epithelial cells.

Zhou X, Hurst RD, Templeton D, Whiteside CI.

Lab Invest. 1995 Sep;73(3):372-83.PMID: 7564270 [PubMed - indexed for MEDLINE]Related articles

Calcium signaling and contractile response of diabetic glomerular mesangial cells.

Whiteside CI, Hurst RD, Stevanovic ZS.

Kidney Int Suppl. 1995 Sep;51:S28-33. No abstract available. PMID: 7474684 [PubMed - indexed for MEDLINE]Related articles

Glomerular mesangial cell altered contractility in high glucose is Ca2+ independent.

Hurst RD, Stevanovic ZS, Munk S, Derylo B, Zhou X, Meer J, Silverberg M, Whiteside CI.

Diabetes. 1995 Jul;44(7):759-66.PMID: 7789643 [PubMed - indexed for MEDLINE]Related articles

Cellular mechanisms of glucose-induced myo-inositol transport upregulation in rat mesangial cells.

Chatzilias AA, Whiteside CI.

Am J Physiol. 1994 Sep;267(3 Pt 2):F459-66.PMID: 8092260 [PubMed - indexed for MEDLINE]Related articles

Demonstration of renal tubular flow by selective angiographic computed tomography.

Potts DG, Brody AS, Shafik IM, Lumsden CJ, Zielinski A, Silverman M, Whiteside CI.

Can Assoc Radiol J. 1993 Oct;44(5):364-70.PMID: 8402237 [PubMed - indexed for MEDLINE]Related articles

Detection of progressive diabetic nephropathy: role of microalbuminuria determination.

Whiteside CI.

Clin Biochem. 1993 Aug;26(4):311-3. No abstract available. PMID: 8242893 [PubMed - indexed for MEDLINE]Related articles

Vascular exchange in the kidney. Regional characterization by multiple indicator tomography.

Lumsden CJ, Silverman M, Zielinski A, Potts DG, Shafik I, Brody AS, Whiteside CI, Violante M.

Circ Res. 1993 Jun;72(6):1172-80.PMID: 8495547 [PubMed - indexed for MEDLINE]Related articlesFree article

Podocytic cytoskeletal disaggregation and basement-membrane detachment in puromycin aminonucleoside nephrosis.

Whiteside CI, Cameron R, Munk S, Levy J.

Am J Pathol. 1993 May;142(5):1641-53.PMID: 8494056 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolated rat glomerular cells demonstrate L-type Ca(2+)-channel activity.

McDermott GF, Hurst RD, Whiteside CI.

Cell Calcium. 1993 May;14(5):387-96.PMID: 7686086 [PubMed - indexed for MEDLINE]Related articles

Epithelial cell detachment in the nephrotic glomerulus: a receptor co-operativity model.

Cho CR, Lumsden CJ, Whiteside CI.

J Theor Biol. 1993 Feb 21;160(4):407-26.PMID: 8501915 [PubMed - indexed for MEDLINE]Related articles

Transmembrane signalling of cholinergic-stimulated contraction in isolated rat glomeruli.

Hurst RD, Whiteside CI, Thompson JC.

Ren Physiol Biochem. 1992 Nov-Dec;15(6):307-17.PMID: 1282724 [PubMed - indexed for MEDLINE]Related articles

Diabetic rat glomerular mesangial cells display normal inositol trisphosphate and calcium release.

Hurst RD, Whiteside CI, Thompson JC.

Am J Physiol. 1992 Oct;263(4 Pt 2):F649-55.PMID: 1415736 [PubMed - indexed for MEDLINE]Related articles

Upregulation of D-myo-inositol transport in diabetic rat glomerular cells.

Whiteside CI, Thompson JC.

Am J Physiol. 1992 Mar;262(3 Pt 1):E301-6.PMID: 1312787 [PubMed - indexed for MEDLINE]Related articles

Myo-inositol and D-glucose transport in rat glomerular and cultured mesangial cells.

Whiteside CI, Thompson JC, Ohayon J.

Am J Physiol. 1991 Jan;260(1 Pt 2):F138-44.PMID: 1992775 [PubMed - indexed for MEDLINE]Related articles

The role of angiotensin-II in progressive diabetic glomerulopathy in the rat.

Whiteside CI, Thompson J.

Endocrinology. 1989 Oct;125(4):1932-40.PMID: 2551633 [PubMed - indexed for MEDLINE]Related articles

Transglomerular cationic macromolecular flux is mediated by a convection-binding mechanism.

Whiteside CI, Lumsden CJ.

Am J Physiol. 1989 May;256(5 Pt 2):F882-93.PMID: 2470261 [PubMed - indexed for MEDLINE]Related articles

In vivo characterization of insulin uptake by dog renal cortical epithelium.

Whiteside CI, Lumsden CJ, Silverman M.

Am J Physiol. 1988 Sep;255(3 Pt 1):E357-65.PMID: 2458680 [PubMed - indexed for MEDLINE]Related articles

The role of percutaneous transluminal dilatation in the treatment of transplant renal artery stenosis.

Whiteside CI, Cardella CJ, Yeung H, de Veber GA, Cook GT.

Clin Nephrol. 1982 Feb;17(2):55-9.PMID: 6461462 [PubMed - indexed for MEDLINE]Related articles