PubMed

The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway.

Rudolf J, Rouillon C, Schwarz-Linek U, White MF.

Nucleic Acids Res. 2009 Nov 20. [Epub ahead of print]PMID: 19933257 [PubMed - as supplied by publisher]

Human IL6 enhances leptin action in mice.

Sadagurski M, Norquay L, Farhang J, D'Aquino K, Copps K, White MF.

Diabetologia. 2009 Nov 10. [Epub ahead of print]PMID: 19902173 [PubMed - as supplied by publisher]Related articles

The IRS2 Gly1057Asp Variant Is Associated With Human Longevity.

Barbieri M, Rizzo MR, Papa M, Boccardi V, Esposito A, White MF, Paolisso G.

J Gerontol A Biol Sci Med Sci. 2009 Nov 3. [Epub ahead of print]PMID: 19887537 [PubMed - as supplied by publisher]Related articles

Foxo1 integrates insulin signaling with mitochondrial function in the liver.

Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF.

Nat Med. 2009 Nov;15(11):1307-11. Epub 2009 Oct 18.PMID: 19838201 [PubMed - in process]Related articles

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.

Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF.

Mol Cell Biol. 2009 Sep;29(18):5070-83. Epub 2009 Jul 13.PMID: 19596788 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor substrate-2 in beta-cells decreases diabetes in nonobese diabetic mice.

Norquay LD, D'Aquino KE, Opare-Addo LM, Kuznetsova A, Haas M, Bluestone JA, White MF.

Endocrinology. 2009 Oct;150(10):4531-40. Epub 2009 Jul 2.PMID: 19574401 [PubMed - indexed for MEDLINE]Related articles

Metformin and insulin meet in a most atypical way.

White MF.

Cell Metab. 2009 Jun;9(6):485-7.PMID: 19490902 [PubMed - indexed for MEDLINE]Related articles

The crenarchaeal DNA damage-inducible transcription factor B paralogue TFB3 is a general activator of transcription.

Paytubi S, White MF.

Mol Microbiol. 2009 Jun;72(6):1487-99. Epub 2009 May 15.PMID: 19460096 [PubMed - indexed for MEDLINE]Related articles

Structure, function and evolution of the XPD family of iron-sulfur-containing 5'-->3' DNA helicases.

White MF.

Biochem Soc Trans. 2009 Jun;37(Pt 3):547-51.PMID: 19442249 [PubMed - indexed for MEDLINE]Related articles

DNA damage: from causes to cures.

Bowater RP, Borts RH, White MF.

Biochem Soc Trans. 2009 Jun;37(Pt 3):479-81.PMID: 19442241 [PubMed - indexed for MEDLINE]Related articles

Structural and functional characterisation of a conserved archaeal RadA paralog with antirecombinase activity.

McRobbie AM, Carter LG, Kerou M, Liu H, McMahon SA, Johnson KA, Oke M, Naismith JH, White MF.

J Mol Biol. 2009 Jun 19;389(4):661-73. Epub 2009 May 3.PMID: 19414020 [PubMed - indexed for MEDLINE]Related articles

Targeted disruption of ROCK1 causes insulin resistance in vivo.

Lee DH, Shi J, Jeoung NH, Kim MS, Zabolotny JM, Lee SW, White MF, Wei L, Kim YB.

J Biol Chem. 2009 May 1;284(18):11776-80. Epub 2009 Mar 10.PMID: 19276091 [PubMed - indexed for MEDLINE]Related articles

AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis.

Schmelz S, Kadi N, McMahon SA, Song L, Oves-Costales D, Oke M, Liu H, Johnson KA, Carter LG, Botting CH, White MF, Challis GL, Naismith JH.

Nat Chem Biol. 2009 Mar;5(3):174-82. Epub 2009 Feb 1.PMID: 19182782 [PubMed - indexed for MEDLINE]Related articlesFree article

RecA family proteins in archaea: RadA and its cousins.

Haldenby S, White MF, Allers T.

Biochem Soc Trans. 2009 Feb;37(Pt 1):102-7.PMID: 19143611 [PubMed - indexed for MEDLINE]Related articles

Reactions to UV damage in the model archaeon Sulfolobus solfataricus.

Fröls S, White MF, Schleper C.

Biochem Soc Trans. 2009 Feb;37(Pt 1):36-41. Review.PMID: 19143598 [PubMed - indexed for MEDLINE]Related articles

Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance.

Copps KD, White MF.

Diabetes. 2009 Jan;58(1):26-7. No abstract available. PMID: 19114728 [PubMed - indexed for MEDLINE]Related articlesFree article

Irs2 inactivation suppresses tumor progression in Pten+/- mice.

Szabolcs M, Keniry M, Simpson L, Reid LJ, Koujak S, Schiff SC, Davidian G, Licata S, Gruvberger-Saal S, Murty VV, Nandula S, Efstratiadis A, Kushner JA, White MF, Parsons R.

Am J Pathol. 2009 Jan;174(1):276-86. Epub 2008 Dec 18.PMID: 19095950 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk factors for severe vision loss immediately after transpupillary thermotherapy for occult subfoveal choroidal neovascularization.

Mason JO 3rd, Colagross CC, Feist RM, White MF, Thomley ML, Vail RS, McGwin G Jr.

Ophthalmic Surg Lasers Imaging. 2008 Nov-Dec;39(6):460-5.PMID: 19065975 [PubMed - indexed for MEDLINE]Related articles

The major architects of chromatin: architectural proteins in bacteria, archaea and eukaryotes.

Luijsterburg MS, White MF, van Driel R, Dame RT.

Crit Rev Biochem Mol Biol. 2008 Nov-Dec;43(6):393-418. Review.PMID: 19037758 [PubMed - indexed for MEDLINE]Related articles

Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase.

McMahon SA, Oke M, Liu H, Johnson KA, Carter L, Kadi N, White MF, Challis GL, Naismith JH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Nov 1;64(Pt 11):1052-5. Epub 2008 Oct 31.PMID: 18997340 [PubMed - indexed for MEDLINE]Related articles

PCNA stimulates catalysis by structure-specific nucleases using two distinct mechanisms: substrate targeting and catalytic step.

Hutton RD, Roberts JA, Penedo JC, White MF.

Nucleic Acids Res. 2008 Dec;36(21):6720-7. Epub 2008 Oct 23.PMID: 18948279 [PubMed - indexed for MEDLINE]Related articlesFree article

Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog.

Oke M, Ching RT, Carter LG, Johnson KA, Liu H, McMahon SA, White MF, Bloch C Jr, Botting CH, Walsh MA, Latiff AA, Kennedy MW, Cooper A, Naismith JH.

Angew Chem Int Ed Engl. 2008;47(41):7853-6. No abstract available. PMID: 18781570 [PubMed - indexed for MEDLINE]Related articles

Macular holes associated with diabetic tractional retinal detachments.

Mason JO, Somaiya MD, White MF Jr, Vail RS.

Ophthalmic Surg Lasers Imaging. 2008 Jul-Aug;39(4):288-93.PMID: 18717433 [PubMed - indexed for MEDLINE]Related articles

Incidence of endophthalmitis following 20-gauge and 25-gauge vitrectomy.

Mason JO 3rd, Yunker JJ, Vail RS, White MF Jr, Feist RM, Thomley ML, Albert MA Jr, Persaud TO.

Retina. 2008 Oct;28(9):1352-4. No abstract available. PMID: 18664933 [PubMed - indexed for MEDLINE]Related articles

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.

Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF.

Cell Metab. 2008 Jul;8(1):65-76.PMID: 18590693 [PubMed - indexed for MEDLINE]Related articles

Structure of the DNA repair helicase XPD.

Liu H, Rudolf J, Johnson KA, McMahon SA, Oke M, Carter L, McRobbie AM, Brown SE, Naismith JH, White MF.

Cell. 2008 May 30;133(5):801-12.PMID: 18510925 [PubMed - indexed for MEDLINE]Related articles

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK.

Nature. 2008 May 29;453(7195):677-81. Epub 2008 Apr 30.PMID: 18449195 [PubMed - indexed for MEDLINE]Related articles

Incidence of acute onset endophthalmitis following intravitreal bevacizumab (Avastin) injection.

Mason JO 3rd, White MF, Feist RM, Thomley ML, Albert MA, Persaud TO, Yunker JJ, Vail RS.

Retina. 2008 Apr;28(4):564-7.PMID: 18398358 [PubMed - indexed for MEDLINE]Related articles

TarO: a target optimisation system for structural biology.

Overton IM, van Niekerk CA, Carter LG, Dawson A, Martin DM, Cameron S, McMahon SA, White MF, Hunter WN, Naismith JH, Barton GJ.

Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W190-6. Epub 2008 Apr 2.PMID: 18385152 [PubMed - indexed for MEDLINE]Related articlesFree article

The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius.

Quaiser A, Constantinesco F, White MF, Forterre P, Elie C.

BMC Mol Biol. 2008 Feb 22;9:25.PMID: 18294364 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.

Tanabe K, Liu Z, Patel S, Doble BW, Li L, Cras-Méneur C, Martinez SC, Welling CM, White MF, Bernal-Mizrachi E, Woodgett JR, Permutt MA.

PLoS Biol. 2008 Feb;6(2):e37.PMID: 18288891 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Wu J, Tseng YD, Xu CF, Neubert TA, White MF, Hubbard SR.

Nat Struct Mol Biol. 2008 Mar;15(3):251-8. Epub 2008 Feb 17.PMID: 18278056 [PubMed - indexed for MEDLINE]Related articles

The archaeal XPB protein is a ssDNA-dependent ATPase with a novel partner.

Richards JD, Cubeddu L, Roberts J, Liu H, White MF.

J Mol Biol. 2008 Feb 22;376(3):634-44. Epub 2007 Dec 15.PMID: 18177890 [PubMed - indexed for MEDLINE]Related articles

The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis.

Li D, Yin X, Zmuda EJ, Wolford CC, Dong X, White MF, Hai T.

Diabetes. 2008 Mar;57(3):635-44. Epub 2007 Dec 5.PMID: 18057093 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains.

Richards JD, Johnson KA, Liu H, McRobbie AM, McMahon S, Oke M, Carter L, Naismith JH, White MF.

J Biol Chem. 2008 Feb 22;283(8):5118-26. Epub 2007 Dec 4.PMID: 18056710 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like signaling, nutrient homeostasis, and life span.

Taguchi A, White MF.

Annu Rev Physiol. 2008;70:191-212. Review.PMID: 17988211 [PubMed - indexed for MEDLINE]Related articles

Responses of hyperthermophilic crenarchaea to UV irradiation.

Götz D, Paytubi S, Munro S, Lundgren M, Bernander R, White MF.

Genome Biol. 2007;8(10):R220.PMID: 17931420 [PubMed - indexed for MEDLINE]Related articlesFree article

The Sulfolobus solfataricus radA paralogue sso0777 is DNA damage inducible and positively regulated by the Sta1 protein.

Abella M, Rodríguez S, Paytubi S, Campoy S, White MF, Barbé J.

Nucleic Acids Res. 2007;35(20):6788-97. Epub 2007 Oct 5.PMID: 17921500 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain IRS2 signaling coordinates life span and nutrient homeostasis.

Taguchi A, Wartschow LM, White MF.

Science. 2007 Jul 20;317(5836):369-72.PMID: 17641201 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.

Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF.

Mol Endocrinol. 2007 Sep;21(9):2294-302. Epub 2007 Jun 19.PMID: 17579213 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase.

Seetharamappa J, Oke M, Liu H, McMahon SA, Johnson KA, Carter L, Dorward M, Zawadzki M, Overton IM, van Niekirk CA, Graham S, Botting CH, Taylor GL, White MF, Barton GJ, Coote PJ, Naismith JH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt 5):452-6. Epub 2007 Apr 28.PMID: 17565195 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase.

Seetharamappa J, Oke M, Liu H, McMahon SA, Johnson KA, Carter L, Dorward M, Zawadzki M, Overton IM, van Niekirk CA, Graham S, Botting CH, Taylor GL, White MF, Barton GJ, Coote PJ, Naismith JH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 1;63(Pt 6):488-91. Epub 2007 May 5.PMID: 17554169 [PubMed - indexed for MEDLINE]Related articlesFree article

An acetylase with relaxed specificity catalyses protein N-terminal acetylation in Sulfolobus solfataricus.

Mackay DT, Botting CH, Taylor GL, White MF.

Mol Microbiol. 2007 Jun;64(6):1540-8. Epub 2007 May 18.PMID: 17511810 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor substrate 1 (IRS-1) plays a unique role in normal epidermal physiology.

Sadagurski M, Nofech-Mozes S, Weingarten G, White MF, Kadowaki T, Wertheimer E.

J Cell Physiol. 2007 Nov;213(2):519-27.PMID: 17508357 [PubMed - indexed for MEDLINE]Related articles

Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.

Kim JJ, Kido Y, Scherer PE, White MF, Accili D.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1694-701. Epub 2007 Feb 13.PMID: 17299086 [PubMed - indexed for MEDLINE]Related articlesFree article

Equal rates of repair of DNA photoproducts in transcribed and non-transcribed strands in Sulfolobus solfataricus.

Dorazi R, Götz D, Munro S, Bernander R, White MF.

Mol Microbiol. 2007 Jan;63(2):521-9. Epub 2006 Dec 5.PMID: 17163966 [PubMed - indexed for MEDLINE]Related articles

Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice.

Gonzalez-Navarro H, Vila-Caballer M, Pastor MF, Vinue A, White MF, Burks D, Andres V.

Front Biosci. 2007 Jan 1;12:2291-8.PMID: 17127239 [PubMed - indexed for MEDLINE]Related articles

CC1, a novel crenarchaeal DNA binding protein.

Luo X, Schwarz-Linek U, Botting CH, Hensel R, Siebers B, White MF.

J Bacteriol. 2007 Jan;189(2):403-9. Epub 2006 Nov 3.PMID: 17085561 [PubMed - indexed for MEDLINE]Related articlesFree article

Crystallization of Ranasmurfin, a blue-coloured protein from Polypedates leucomystax.

McMahon SA, Walsh MA, Ching RT, Carter LG, Dorward M, Johnson KA, Liu H, Oke M, Bloch C Jr, Kennedy MW, Latiff AA, Cooper A, Taylor GL, White MF, Naismith JH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt 11):1124-6. Epub 2006 Oct 20.PMID: 17077494 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis.

Ma Z, Gibson SL, Byrne MA, Zhang J, White MF, Shaw LM.

Mol Cell Biol. 2006 Dec;26(24):9338-51. Epub 2006 Oct 9.PMID: 17030605 [PubMed - indexed for MEDLINE]Related articlesFree article