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    Results: 15

    1.

    Eleven Amino Acid Glucagon-like Peptide-1 Receptor Agonists with Antidiabetic Activity.

    Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L, Taylor JR, Koplowitz B, Chi CL, Khanna A, Robinson GW, Seethala R, Antal-Zimanyi IA, Stoffel RH, Han S, Whaley JM, Huang CS, Krupinski J, Ewing WR.

    J Med Chem. 2009 Aug 24. [Epub ahead of print]PMID: 19702274 [PubMed - as supplied by publisher]Related articles

    2.

    Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.

    Ellsworth BA, Meng W, Patel M, Girotra RN, Wu G, Sher PM, Hagan DL, Obermeier MT, Humphreys WG, Robertson JG, Wang A, Han S, Waldron TL, Morgan NN, Whaley JM, Washburn WN.

    Bioorg Med Chem Lett. 2008 Sep 1;18(17):4770-3. Epub 2008 Jul 31.PMID: 18707880 [PubMed - indexed for MEDLINE]Related articles

    3.

    Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats.

    Han S, Hagan DL, Taylor JR, Xin L, Meng W, Biller SA, Wetterau JR, Washburn WN, Whaley JM.

    Diabetes. 2008 Jun;57(6):1723-9. Epub 2008 Mar 20.PMID: 18356408 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.

    Meng W, Ellsworth BA, Nirschl AA, McCann PJ, Patel M, Girotra RN, Wu G, Sher PM, Morrison EP, Biller SA, Zahler R, Deshpande PP, Pullockaran A, Hagan DL, Morgan N, Taylor JR, Obermeier MT, Humphreys WG, Khanna A, Discenza L, Robertson JG, Wang A, Han S, Wetterau JR, Janovitz EB, Flint OP, Whaley JM, Washburn WN.

    J Med Chem. 2008 Mar 13;51(5):1145-9. Epub 2008 Feb 9.PMID: 18260618 [PubMed - indexed for MEDLINE]Related articles

    5.

    Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity.

    Blankenship C, Naglich JG, Whaley JM, Seizinger B, Kley N.

    Oncogene. 1999 Feb 25;18(8):1529-35.PMID: 10102622 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.

    Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG Jr, Iliopoulos O.

    Mol Cell. 1998 Jun;1(7):959-68.PMID: 9651579 [PubMed - indexed for MEDLINE]Related articles

    7.

    Tau protein in cerebrospinal fluid as an aid in the diagnosis of Alzheimer's disease.

    Munroe WA, Southwick PC, Chang L, Scharre DW, Echols CL Jr, Fu PC, Whaley JM, Wolfert RL.

    Ann Clin Lab Sci. 1995 May-Jun;25(3):207-17.PMID: 7605102 [PubMed - indexed for MEDLINE]Related articles

    8.

    Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: implications for the potential organization of the human von Hippel-Lindau disease gene.

    Gao J, Naglich JG, Laidlaw J, Whaley JM, Seizinger BR, Kley N.

    Cancer Res. 1995 Feb 15;55(4):743-7.PMID: 7850784 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.

    Whaley JM, Naglich J, Gelbert L, Hsia YE, Lamiell JM, Green JS, Collins D, Neumann HP, Laidlaw J, Li FP, et al.

    Am J Hum Genet. 1994 Dec;55(6):1092-102. Erratum in: Am J Hum Genet 1995 Jan;56(1):356. PMID: 7977367 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Comparative study of p53 gene and protein alterations in human astrocytic tumors.

    Louis DN, von Deimling A, Chung RY, Rubio MP, Whaley JM, Eibl RH, Ohgaki H, Wiestler OD, Thor AD, Seizinger BR.

    J Neuropathol Exp Neurol. 1993 Jan;52(1):31-8.PMID: 8381161 [PubMed - indexed for MEDLINE]Related articles

    11.

    Cytogenetic and molecular studies of a familial renal cell carcinoma.

    Decker HJ, Wullich B, Whaley JM, Herrera G, Klauck SM, Sandberg AA, Yandell DW, Seizinger BR.

    Cancer Genet Cytogenet. 1992 Oct 1;63(1):25-31.PMID: 1423222 [PubMed - indexed for MEDLINE]Related articles

    12.

    Efficient mutation induction by 125I and 131I decays in DNA of human cells.

    Whaley JM, Little JB.

    Radiat Res. 1990 Jul;123(1):68-74.PMID: 2371380 [PubMed - indexed for MEDLINE]Related articles

    13.

    Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.

    Menon AG, Anderson KM, Riccardi VM, Chung RY, Whaley JM, Yandell DW, Farmer GE, Freiman RN, Lee JK, Li FP, et al.

    Proc Natl Acad Sci U S A. 1990 Jul;87(14):5435-9.PMID: 2142531 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Mutation induction by 125iodoacetylproflavine, a DNA-intercalating agent, in human cells.

    Whaley JM, Kassis AI, Kinsey BM, Adelstein SJ, Little JB.

    Int J Radiat Biol. 1990 Jun;57(6):1087-103.PMID: 1971836 [PubMed - indexed for MEDLINE]Related articles

    15.

    Molecular characterization of hprt mutants induced by low- and high-LET radiations in human cells.

    Whaley JM, Little JB.

    Mutat Res. 1990 Jan;243(1):35-45.PMID: 2300083 [PubMed - indexed for MEDLINE]Related articles

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