PubMed

Drusen deposits contain soluble and mature amyloid fibrils.

Isas JM, Luibl V, Johnson LV, Kayed R, Wetzel R, Glabe CG, Langen R, Chen J.

Invest Ophthalmol Vis Sci. 2009 Nov 5. [Epub ahead of print]PMID: 19892876 [PubMed - as supplied by publisher]Related articles

The impact of ataxin-1-like histidine insertions on polyglutamine aggregation.

Jayaraman M, Kodali R, Wetzel R.

Protein Eng Des Sel. 2009 Aug;22(8):469-78. Epub 2009 Jun 18.PMID: 19541676 [PubMed - indexed for MEDLINE]Related articles

Structures of Abeta-related peptide--monoclonal antibody complexes.

Gardberg A, Dice L, Pridgen K, Ko J, Patterson P, Ou S, Wetzel R, Dealwis C.

Biochemistry. 2009 Jun 16;48(23):5210-7.PMID: 19385664 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer.

Yu J, Kane S, Wu J, Benedettini E, Li D, Reeves C, Innocenti G, Wetzel R, Crosby K, Becker A, Ferrante M, Cheung WC, Hong X, Chirieac LR, Sholl LM, Haack H, Smith BL, Polakiewicz RD, Tan Y, Gu TL, Loda M, Zhou X, Comb MJ.

Clin Cancer Res. 2009 May 1;15(9):3023-8. Epub 2009 Apr 14.PMID: 19366827 [PubMed - indexed for MEDLINE]Related articles

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.

Thakur AK, Jayaraman M, Mishra R, Thakur M, Chellgren VM, Byeon IJ, Anjum DH, Kodali R, Creamer TP, Conway JF, Gronenborn AM, Wetzel R.

Nat Struct Mol Biol. 2009 Apr;16(4):380-9. Epub 2009 Mar 8.PMID: 19270701 [PubMed - indexed for MEDLINE]Related articlesFree article

Who is doing what to whom: a large prospective study of propofol anesthesia in children.

Wetzel RC.

Anesth Analg. 2009 Mar;108(3):695-8. No abstract available. PMID: 19224769 [PubMed - indexed for MEDLINE]Related articles

Support for PICUs and the PRISM scoring algorithms.

Gorman M, Sachdeva R, Rice T, Wetzel R.

Pediatr Crit Care Med. 2009 Jan;10(1):143-4. No abstract available. PMID: 19131881 [PubMed - indexed for MEDLINE]Related articles

Natural organic matter and sunlight accelerate the degradation of 17ss-estradiol in water.

Leech DM, Snyder MT, Wetzel RG.

Sci Total Environ. 2009 Mar 1;407(6):2087-92. Epub 2008 Dec 31.PMID: 19118869 [PubMed - indexed for MEDLINE]Related articles

Databases for assessing the outcomes of the treatment of patients with congenital and paediatric cardiac disease--the perspective of critical care.

LaRovere JM, Jeffries HE, Sachdeva RC, Rice TB, Wetzel RC, Cooper DS, Bird GL, Ghanayem NS, Checchia PA, Chang AC, Wessel DL.

Cardiol Young. 2008 Dec;18 Suppl 2:130-6. Review.PMID: 19063783 [PubMed - indexed for MEDLINE]Related articles

A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways.

Steinert S, Lee E, Tresset G, Zhang D, Hortsch R, Wetzel R, Hebbar S, Sundram JR, Kesavapany S, Boschke E, Kraut R.

PLoS One. 2008 Aug 13;3(8):e2933.PMID: 18716682 [PubMed - indexed for MEDLINE]Related articlesFree article

Phone respondents reported less mental health problems whereas mail interviewee gave higher physical health ratings.

Ravens-Sieberer U, Erhart M, Wetzel R, Krügel A, Brambosch A.

J Clin Epidemiol. 2008 Oct;61(10):1056-60. Epub 2008 Jun 6.PMID: 18538990 [PubMed - indexed for MEDLINE]Related articles

Signaling networks assembled by oncogenic EGFR and c-Met.

Guo A, Villén J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, Wang Y, MacNeill J, Mitchell J, Gygi SP, Rush J, Polakiewicz RD, Comb MJ.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):692-7. Epub 2008 Jan 7.PMID: 18180459 [PubMed - indexed for MEDLINE]Related articlesFree article

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.

Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ.

Cell. 2007 Dec 14;131(6):1190-203.PMID: 18083107 [PubMed - indexed for MEDLINE]Related articles

Designing a comprehensive model for critical care orientation.

Morris LL, Pfeifer PB, Catalano R, Fortney R, Hilton EL, McLaughlin J, Nelson G, Palamone J, Rabito R, Wetzel R, Goldstein L.

Crit Care Nurse. 2007 Dec;27(6):37-40, 42-4, 46-8 passim; quiz 61. No abstract available. PMID: 18032685 [PubMed - indexed for MEDLINE]Related articles

Amyloid adhesins are abundant in natural biofilms.

Larsen P, Nielsen JL, Dueholm MS, Wetzel R, Otzen D, Nielsen PH.

Environ Microbiol. 2007 Dec;9(12):3077-90.PMID: 17991035 [PubMed - indexed for MEDLINE]Related articles

In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence.

Ignatova Z, Thakur AK, Wetzel R, Gierasch LM.

J Biol Chem. 2007 Dec 14;282(50):36736-43. Epub 2007 Oct 17.PMID: 17942400 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular basis for passive immunotherapy of Alzheimer's disease.

Gardberg AS, Dice LT, Ou S, Rich RL, Helmbrecht E, Ko J, Wetzel R, Myszka DG, Patterson PH, Dealwis C.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15659-64. Epub 2007 Sep 25.PMID: 17895381 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium: a double-edged sword.

Wetzel RC.

Pediatr Crit Care Med. 2007 May;8(3):300-1. No abstract available. PMID: 17496519 [PubMed - indexed for MEDLINE]Related articles

Polymorphism in the intermediates and products of amyloid assembly.

Kodali R, Wetzel R.

Curr Opin Struct Biol. 2007 Feb;17(1):48-57. Epub 2007 Jan 23. Review.PMID: 17251001 [PubMed - indexed for MEDLINE]Related articles

Plasticity of amyloid fibrils.

Wetzel R, Shivaprasad S, Williams AD.

Biochemistry. 2007 Jan 9;46(1):1-10. Review.PMID: 17198370 [PubMed - indexed for MEDLINE]Related articlesFree article

Interrater reliability and coding guide for nonpsychotic formal thought disorder.

North CS, Kienstra DM, Osborne VA, Dokucu ME, Vassilenko M, Hong B, Wetzel RD, Spitznagel EL.

Percept Mot Skills. 2006 Oct;103(2):395-411.PMID: 17165403 [PubMed - indexed for MEDLINE]Related articles

Generic health-related quality-of-life assessment in children and adolescents: methodological considerations.

Ravens-Sieberer U, Erhart M, Wille N, Wetzel R, Nickel J, Bullinger M.

Pharmacoeconomics. 2006;24(12):1199-220. Review.PMID: 17129075 [PubMed - indexed for MEDLINE]Related articles

Positive end-expiratory pressure and pressure support in peripheral airways obstruction : work of breathing in intubated children.

Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJ.

Intensive Care Med. 2007 Jan;33(1):120-7. Epub 2006 Nov 17.PMID: 17111110 [PubMed - indexed for MEDLINE]Related articles

Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions.

Crick SL, Jayaraman M, Frieden C, Wetzel R, Pappu RV.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16764-9. Epub 2006 Oct 30.PMID: 17075061 [PubMed - indexed for MEDLINE]Related articlesFree article

A triaxial probe for on-line proteolysis coupled with hydrogen/deuterium exchange-electrospray mass spectrometry.

Chen M, Cook KD, Kheterpal I, Wetzel R.

J Am Soc Mass Spectrom. 2007 Feb;18(2):208-17. Epub 2006 Oct 30.PMID: 17074502 [PubMed - indexed for MEDLINE]Related articles

Imaging polyglutamine deposits in brain tissue.

Osmand AP, Berthelier V, Wetzel R.

Methods Enzymol. 2006;412:106-22. Review.PMID: 17046655 [PubMed - indexed for MEDLINE]Related articles

Screening for modulators of aggregation with a microplate elongation assay.

Berthelier V, Wetzel R.

Methods Enzymol. 2006;413:313-25.PMID: 17046403 [PubMed - indexed for MEDLINE]Related articles

Analysis of amyloid fibril structure by scanning cysteine mutagenesis.

Shivaprasad S, Wetzel R.

Methods Enzymol. 2006;413:182-98.PMID: 17046397 [PubMed - indexed for MEDLINE]Related articles

Hydrogen/deuterium exchange mass spectrometry analysis of protein aggregates.

Kheterpal I, Cook KD, Wetzel R.

Methods Enzymol. 2006;413:140-66.PMID: 17046395 [PubMed - indexed for MEDLINE]Related articles

Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay.

O'Nuallain B, Thakur AK, Williams AD, Bhattacharyya AM, Chen S, Thiagarajan G, Wetzel R.

Methods Enzymol. 2006;413:34-74.PMID: 17046390 [PubMed - indexed for MEDLINE]Related articles

Common threads in neurodegenerative disorders of aging.

Flint Beal M, Bossy-Wetzel E, Finkbeiner S, Fiskum G, Giasson B, Johnson C, Khachaturian ZS, Lee VM, Nicholls D, Reddy H, Reynolds I, Teplow DB, Thal LJ, Trojanowski JQ, Walsh DM, Wetzel R, Wexler NS, Young AB, Bain L.

Alzheimers Dement. 2006 Oct;2(4):322-6. No abstract available. PMID: 19595906 [PubMed - in process]Related articles

Don't confuse the anesthetic with the anesthesiologist!

Wetzel RC.

Anesth Analg. 2006 Oct;103(4):859-62. No abstract available. PMID: 17000794 [PubMed - indexed for MEDLINE]Related articlesFree article

Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease.

Nguyen HP, Kobbe P, Rahne H, Wörpel T, Jäger B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kántor O, Petrasch-Parwez E, Wetzel R, Osmand A, von Hörsten S.

Hum Mol Genet. 2006 Nov 1;15(21):3177-94. Epub 2006 Sep 19.PMID: 16984963 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetics and thermodynamics of amyloid fibril assembly.

Wetzel R.

Acc Chem Res. 2006 Sep;39(9):671-9. Review.PMID: 16981684 [PubMed - indexed for MEDLINE]Related articles

Hydrogen/deuterium exchange mass spectrometry--a window into amyloid structure.

Kheterpal I, Wetzel R.

Acc Chem Res. 2006 Sep;39(9):584-93. Review.PMID: 16981674 [PubMed - indexed for MEDLINE]Related articles

Amyloid fibrils--common threads in the natural history of proteins.

Wetzel R.

Acc Chem Res. 2006 Sep;39(9):567. No abstract available. PMID: 16981671 [PubMed]Related articles

Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins.

Slepko N, Bhattacharyya AM, Jackson GR, Steffan JS, Marsh JL, Thompson LM, Wetzel R.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14367-72. Epub 2006 Sep 15.PMID: 16980414 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural differences in Abeta amyloid protofibrils and fibrils mapped by hydrogen exchange--mass spectrometry with on-line proteolytic fragmentation.

Kheterpal I, Chen M, Cook KD, Wetzel R.

J Mol Biol. 2006 Aug 25;361(4):785-95. Epub 2006 Jul 12.PMID: 16875699 [PubMed - indexed for MEDLINE]Related articles

Pediatric cardiac critical care patients should be cared for by intensivists.

Baden HP, Berger J, Brilli RI, Burns JP, Checchia PA, Dalton HJ, Nadkarni V, Pollack M, Wetzel RC, Zimmerman JJ.

J Am Coll Cardiol. 2006 Jul 4;48(1):221-2; author reply 222-3. Epub 2006 Jun 9. No abstract available. PMID: 16814678 [PubMed - indexed for MEDLINE]Related articles

Benefits vs the harms of automated external defibrillator use.

Landau WM, Jaffe AS, Wetzel RD.

JAMA. 2006 Jun 28;295(24):2849-50; author reply 2850. No abstract available. PMID: 16804150 [PubMed - indexed for MEDLINE]Related articles

Precise use of medical terminology.

Wetzel RC.

Crit Care Med. 2006 Jun;34(6):1854; author reply 1854-5. No abstract available. PMID: 16715005 [PubMed - indexed for MEDLINE]Related articles

[Minimally invasive approach to implantation of a hip endoprosthesis]

Wetzel R, Dorsch M.

Orthopade. 2006 Jul;35(7):738-43. German. PMID: 16710721 [PubMed - indexed for MEDLINE]Related articles

Nucleation of huntingtin aggregation in cells.

Wetzel R.

Nat Chem Biol. 2006 Jun;2(6):297-8. No abstract available. PMID: 16710335 [PubMed - indexed for MEDLINE]Related articles

Intensivist-led team approach to critical care of children with heart disease.

Baden HP, Zimmerman JJ, Brilli RJ, Wong H, Wetzel RC, Burns JP, Nadkarni V, Checchia PA, Dalton HJ, Berger J, Pollack M, Notterman D, Green TP, Blumer J, Dean M.

Pediatrics. 2006 May;117(5):1854-6; author reply 1856-7. No abstract available. Erratum in: Pediatrics. 2007 Feb;119(2):424. PMID: 16651353 [PubMed - indexed for MEDLINE]Related articlesFree article

CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity.

Arango M, Holbert S, Zala D, Brouillet E, Pearson J, Régulier E, Thakur AK, Aebischer P, Wetzel R, Déglon N, Néri C.

J Neurosci. 2006 Apr 26;26(17):4649-59.PMID: 16641246 [PubMed - indexed for MEDLINE]Related articlesFree article

Gastrointestinal morbidity after Norwood palliation for hypoplastic left heart syndrome.

Jeffries HE, Wells WJ, Starnes VA, Wetzel RC, Moromisato DY.

Ann Thorac Surg. 2006 Mar;81(3):982-7.PMID: 16488706 [PubMed - indexed for MEDLINE]Related articles

Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability.

Williams AD, Shivaprasad S, Wetzel R.

J Mol Biol. 2006 Apr 7;357(4):1283-94. Epub 2006 Jan 30.PMID: 16476445 [PubMed - indexed for MEDLINE]Related articles

Altruistic living donors: evaluation for nondirected kidney or liver donation.

Jendrisak MD, Hong B, Shenoy S, Lowell J, Desai N, Chapman W, Vijayan A, Wetzel RD, Smith M, Wagner J, Brennan S, Brockmeier D, Kappel D.

Am J Transplant. 2006 Jan;6(1):115-20.PMID: 16433765 [PubMed - indexed for MEDLINE]Related articles

[Initial stability of press-fit acetabular cups--an in-vitro study]

Wetzel R, Simnacher M, Scheller G.

Biomed Tech (Berl). 2005 Dec;50(12):400-3. German. PMID: 16429943 [PubMed - indexed for MEDLINE]Related articles

Oligoproline effects on polyglutamine conformation and aggregation.

Bhattacharyya A, Thakur AK, Chellgren VM, Thiagarajan G, Williams AD, Chellgren BW, Creamer TP, Wetzel R.

J Mol Biol. 2006 Jan 20;355(3):524-35. Epub 2005 Nov 9.PMID: 16321399 [PubMed - indexed for MEDLINE]Related articles