PubMed

Prevention of Cardiac Dysfunction in Acute Coxsackievirus B3 Cardiomyopathy by Inducible Expression of a Soluble Coxsackievirus-Adenovirus Receptor.

Pinkert S, Westermann D, Wang X, Klingel K, Dörner A, Savvatis K, Größl T, Krohn S, Tschöpe C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H.

Circulation. 2009 Nov 23. [Epub ahead of print]PMID: 19933937 [PubMed - as supplied by publisher]

Absence of thrombospondin-2 causes age-related dilated cardiomyopathy.

Swinnen M, Vanhoutte D, Van Almen GC, Hamdani N, Schellings MW, D'hooge J, Van der Velden J, Weaver MS, Sage EH, Bornstein P, Verheyen FK, VandenDriessche T, Chuah MK, Westermann D, Paulus WJ, Van de Werf F, Schroen B, Carmeliet P, Pinto YM, Heymans S.

Circulation. 2009 Oct 20;120(16):1585-97. Epub 2009 Oct 5.PMID: 19805649 [PubMed - indexed for MEDLINE]Related articles

Immunomodulation and matrix metalloproteinases in viral myocarditis.

Westermann D, Savvatis K, Schultheiss HP, Tschöpe C.

J Mol Cell Cardiol. 2009 Sep 1. [Epub ahead of print]PMID: 19729021 [PubMed - as supplied by publisher]Related articles

Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure.

Wachter R, Schmidt-Schweda S, Westermann D, Post H, Edelmann F, Kasner M, Lüers C, Steendijk P, Hasenfuß G, Tschöpe C, Pieske B.

Eur Heart J. 2009 Aug 30. [Epub ahead of print]PMID: 19720638 [PubMed - as supplied by publisher]Related articles

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.

Granzier HL, Radke MH, Peng J, Westermann D, Nelson OL, Rost K, King NM, Yu Q, Tschöpe C, McNabb M, Larson DF, Labeit S, Gotthardt M.

Circ Res. 2009 Sep 11;105(6):557-64. Epub 2009 Aug 13.PMID: 19679835 [PubMed - indexed for MEDLINE]Related articles

High-risk clinical stage I nonseminomatous germ cell tumors: the case for chemotherapy.

Westermann DH, Studer UE.

World J Urol. 2009 Aug;27(4):455-61. Epub 2009 Jul 28.PMID: 19636566 [PubMed - in process]Related articles

Three-dimensional alignment of the aggregated myocytes in the normal and hypertrophic murine heart.

Schmitt B, Fedarava K, Falkenberg J, Rothaus K, Bodhey NK, Reischauer C, Kozerke S, Schnackenburg B, Westermann D, Lunkenheimer PP, Anderson RH, Berger F, Kuehne T.

J Appl Physiol. 2009 Sep;107(3):921-7. Epub 2009 Jul 23.PMID: 19628727 [PubMed - indexed for MEDLINE]Related articles

Heart failure with normal ejection fraction. Pathophysiology, diagnosis, and treatment.

Tschöpe C, Westermann D.

Herz. 2009 Mar;34(2):89-96. Review.PMID: 19370324 [PubMed - indexed for MEDLINE]Related articles

Cardiac deletion of the Coxsackievirus-adenovirus receptor abolishes Coxsackievirus B3 infection and prevents myocarditis in vivo.

Shi Y, Chen C, Lisewski U, Wrackmeyer U, Radke M, Westermann D, Sauter M, Tschöpe C, Poller W, Klingel K, Gotthardt M.

J Am Coll Cardiol. 2009 Apr 7;53(14):1219-26.PMID: 19341864 [PubMed - indexed for MEDLINE]Related articles

Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy.

Westermann D, Walther T, Savvatis K, Escher F, Sobirey M, Riad A, Bader M, Schultheiss HP, Tschöpe C.

Diabetes. 2009 Jun;58(6):1373-81. Epub 2009 Mar 10.PMID: 19276445 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure.

Westermann D, Riad A, Richter U, Jäger S, Savvatis K, Schuchardt M, Bergmann N, Tölle M, Nagorsen D, Gotthardt M, Schultheiss HP, Tschöpe C.

Basic Res Cardiol. 2009 Sep;104(5):499-509. Epub 2009 Mar 3.PMID: 19255799 [PubMed - in process]Related articles

Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells.

Ladhoff J, Bader M, Brösel S, Effenberger E, Westermann D, Volk HD, Seifert M.

Cell Res. 2009 Apr;19(4):507-18.PMID: 19238174 [PubMed - indexed for MEDLINE]Related articles

Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.

Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, Weger S, Kurreck J, Erdmann V, Tschope C, Pieske B, Lebeche D, Schultheiss HP, Hajjar RJ, Poller WC.

Circulation. 2009 Mar 10;119(9):1241-52. Epub 2009 Feb 23.PMID: 19237664 [PubMed - indexed for MEDLINE]Related articles

[Urinary diversions: which one one is right for which patient?]

Bader P, Westermann D, Frohneberg D.

Urologe A. 2009 Feb;48(2):127-36. Review. German. PMID: 19169659 [PubMed - indexed for MEDLINE]Related articles

Pretreatment with statin attenuates the cardiotoxicity of Doxorubicin in mice.

Riad A, Bien S, Westermann D, Becher PM, Loya K, Landmesser U, Kroemer HK, Schultheiss HP, Tschöpe C.

Cancer Res. 2009 Jan 15;69(2):695-9.PMID: 19147586 [PubMed - indexed for MEDLINE]Related articles

Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure.

Westermann D, Riad A, Lettau O, Roks A, Savvatis K, Becher PM, Escher F, Jan Danser AH, Schultheiss HP, Tschöpe C.

Hypertension. 2008 Dec;52(6):1068-75. Epub 2008 Oct 27.PMID: 18955663 [PubMed - indexed for MEDLINE]Related articles

Enhancement of endothelial nitric oxide synthase production reverses vascular dysfunction and inflammation in the hindlimbs of a rat model of diabetes.

Riad A, Westermann D, Van Linthout S, Mohr Z, Uyulmaz S, Becher PM, Rütten H, Wohlfart P, Peters H, Schultheiss HP, Tschöpe C.

Diabetologia. 2008 Dec;51(12):2325-32. Epub 2008 Sep 30.PMID: 18825362 [PubMed - indexed for MEDLINE]Related articles

Doxorubicin cardiomyopathy-induced inflammation and apoptosis are attenuated by gene deletion of the kinin B1 receptor.

Westermann D, Lettau O, Sobirey M, Riad A, Bader M, Schultheiss HP, Tschöpe C.

Biol Chem. 2008 Jun;389(6):713-8.PMID: 18627295 [PubMed - indexed for MEDLINE]Related articles

Development of diabetic cardiomyopathy and the kallikrein-kinin system--new insights from B1 and B2 receptor signaling.

Tschöpe C, Westermann D.

Biol Chem. 2008 Jun;389(6):707-11. Review.PMID: 18627288 [PubMed - indexed for MEDLINE]Related articles

Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy.

Fechner H, Sipo I, Westermann D, Pinkert S, Wang X, Suckau L, Kurreck J, Zeichhardt H, Müller O, Vetter R, Erdmann V, Tschope C, Poller W.

J Mol Med. 2008 Sep;86(9):987-97. Epub 2008 Jun 12.PMID: 18548221 [PubMed - indexed for MEDLINE]Related articles

Additional lack of iNOS attenuates diastolic dysfunction in aged ET-1 transgenic mice.

Kalk P, Westermann D, Herzfeld S, Relle K, Pfab T, Bauer C, Tschöpe C, Stasch JP, Hocher B.

Can J Physiol Pharmacol. 2008 Jun;86(6):353-7.PMID: 18516098 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice.

Riad A, Jäger S, Sobirey M, Escher F, Yaulema-Riss A, Westermann D, Karatas A, Heimesaat MM, Bereswill S, Dragun D, Pauschinger M, Schultheiss HP, Tschöpe C.

J Immunol. 2008 May 15;180(10):6954-61.PMID: 18453617 [PubMed - indexed for MEDLINE]Related articlesFree article

Renin inhibitors, clinical experience.

Westermann D, Schmieder R, Schultheiss HP, Tschöpe C.

J Mol Med. 2008 Jun;86(6):691-5. Epub 2008 Apr 25. Review.PMID: 18437334 [PubMed - indexed for MEDLINE]Related articles

Role of left ventricular stiffness in heart failure with normal ejection fraction.

Westermann D, Kasner M, Steendijk P, Spillmann F, Riad A, Weitmann K, Hoffmann W, Poller W, Pauschinger M, Schultheiss HP, Tschöpe C.

Circulation. 2008 Apr 22;117(16):2051-60. Epub 2008 Apr 14.PMID: 18413502 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice.

Riad A, Bien S, Gratz M, Escher F, Westermann D, Heimesaat MM, Bereswill S, Krieg T, Felix SB, Schultheiss HP, Kroemer HK, Tschöpe C.

Eur J Heart Fail. 2008 Mar;10(3):233-43. Epub 2008 Mar 5.PMID: 18321777 [PubMed - indexed for MEDLINE]Related articles

Biglycan is required for adaptive remodeling after myocardial infarction.

Westermann D, Mersmann J, Melchior A, Freudenberger T, Petrik C, Schaefer L, Lüllmann-Rauch R, Lettau O, Jacoby C, Schrader J, Brand-Herrmann SM, Young MF, Schultheiss HP, Levkau B, Baba HA, Unger T, Zacharowski K, Tschöpe C, Fischer JW.

Circulation. 2008 Mar 11;117(10):1269-76. Epub 2008 Feb 25.PMID: 18299507 [PubMed - indexed for MEDLINE]Related articlesFree article

The cardiovascular influence of interleukin-1 beta on the expression of bradykinin B1 and B2 receptors.

Riad A, Walther T, Yang J, Altmann C, Escher F, Westermann D, Spillmann F, Schultheiss HP, Tschöpe C.

Int Immunopharmacol. 2008 Feb;8(2):222-30. Epub 2007 Aug 21.PMID: 18182231 [PubMed - indexed for MEDLINE]Related articles

New perspective on the tissue kallikrein-kinin system in myocardial infarction: role of angiogenesis and cardiac regeneration.

Westermann D, Schultheiss HP, Tschöpe C.

Int Immunopharmacol. 2008 Feb;8(2):148-54. Epub 2007 Aug 17. Review.PMID: 18182218 [PubMed - indexed for MEDLINE]Related articles

Cardiac overexpression of human VEGF(165) by recombinant Semliki Forest virus leads to adverse effects in pressure-induced heart failure.

Loot AE, Roks AJ, Westermann D, Orzechowski HD, Tschöpe C, Wilschut JC, Tio RA, van Gilst WH, Henning RH.

Neth Heart J. 2007;15(10):335-41.PMID: 18167566 [PubMed - in process]Related articlesFree article

Up-regulation of PPARgamma in myocardial infarction.

Fliegner D, Westermann D, Riad A, Schubert C, Becher E, Fielitz J, Tschöpe C, Regitz-Zagrosek V.

Eur J Heart Fail. 2008 Jan;10(1):30-8. Epub 2007 Dec 27.PMID: 18162196 [PubMed - indexed for MEDLINE]Related articles

Long-term followup results of 1 cycle of adjuvant bleomycin, etoposide and cisplatin chemotherapy for high risk clinical stage I nonseminomatous germ cell tumors of the testis.

Westermann DH, Schefer H, Thalmann GN, Karamitopoulou-Diamantis E, Fey MF, Studer UE.

J Urol. 2008 Jan;179(1):163-6. Epub 2007 Nov 14.PMID: 18001800 [PubMed - indexed for MEDLINE]Related articles

The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy.

Bien S, Riad A, Ritter CA, Gratz M, Olshausen F, Westermann D, Grube M, Krieg T, Ciecholewski S, Felix SB, Staudt A, Schultheiss HP, Ewert R, Völker U, Tschöpe C, Kroemer HK.

Cancer Res. 2007 Nov 1;67(21):10428-35.PMID: 17974986 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy.

Westermann D, Van Linthout S, Dhayat S, Dhayat N, Schmidt A, Noutsias M, Song XY, Spillmann F, Riad A, Schultheiss HP, Tschöpe C.

Basic Res Cardiol. 2007 Nov;102(6):500-7. Epub 2007 Oct 5.PMID: 17909696 [PubMed - indexed for MEDLINE]Related articles

Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus.

Riad A, Du J, Stiehl S, Westermann D, Mohr Z, Sobirey M, Doehner W, Adams V, Pauschinger M, Schultheiss HP, Tschöpe C.

Eur J Pharmacol. 2007 Aug 27;569(3):204-11. Epub 2007 May 24.PMID: 17669395 [PubMed - indexed for MEDLINE]Related articles

Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study.

Kasner M, Westermann D, Steendijk P, Gaub R, Wilkenshoff U, Weitmann K, Hoffmann W, Poller W, Schultheiss HP, Pauschinger M, Tschöpe C.

Circulation. 2007 Aug 7;116(6):637-47. Epub 2007 Jul 23.PMID: 17646587 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.

Van Linthout S, Riad A, Dhayat N, Spillmann F, Du J, Dhayat S, Westermann D, Hilfiker-Kleiner D, Noutsias M, Laufs U, Schultheiss HP, Tschöpe C.

Diabetologia. 2007 Sep;50(9):1977-86. Epub 2007 Jun 23.PMID: 17589825 [PubMed - indexed for MEDLINE]Related articles

Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy.

Westermann D, Van Linthout S, Dhayat S, Dhayat N, Escher F, Bücker-Gärtner C, Spillmann F, Noutsias M, Riad A, Schultheiss HP, Tschöpe C.

Diabetes. 2007 Jul;56(7):1834-41. Epub 2007 May 1.PMID: 17473225 [PubMed - indexed for MEDLINE]Related articlesFree article

Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium.

Spillmann F, Graiani G, Van Linthout S, Meloni M, Campesi I, Lagrasta C, Westermann D, Tschöpe C, Quaini F, Emanueli C, Madeddu P.

Regen Med. 2006 Mar;1(2):235-54.PMID: 17465807 [PubMed - indexed for MEDLINE]Related articles

Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism.

Westermann D, Rutschow S, Jäger S, Linderer A, Anker S, Riad A, Unger T, Schultheiss HP, Pauschinger M, Tschöpe C.

Diabetes. 2007 Mar;56(3):641-6.PMID: 17327431 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.

Walther T, Tschöpe C, Sterner-Kock A, Westermann D, Heringer-Walther S, Riad A, Nikolic A, Wang Y, Ebermann L, Siems WE, Bader M, Shakibaei M, Schultheiss HP, Dörner A.

Circulation. 2007 Jan 23;115(3):333-44. Epub 2007 Jan 8.PMID: 17210842 [PubMed - indexed for MEDLINE]Related articlesFree article

[Angina pectoris and ST-elevation after chemotherapy with 5-fluorouracil]

Spencker S, Schmittel A, Westermann D, Marek A, Schultheiss HP, Witzenbichler B.

Internist (Berl). 2007 Jan;48(1):69-72, 74. German. PMID: 17177034 [PubMed - indexed for MEDLINE]Related articles

Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis.

Li J, Leschka S, Rutschow S, Schwimmbeck PL, Husmann L, Noutsias M, Westermann D, Poller W, Zeichhardt H, Klingel K, Tschope C, Schultheiss HP, Pauschinger M.

Eur J Pharmacol. 2007 Jan 5;554(1):60-8. Epub 2006 Aug 26.PMID: 17113076 [PubMed - indexed for MEDLINE]Related articles

Chronic inhibition of p38MAPK improves cardiac and endothelial function in experimental diabetes mellitus.

Riad A, Unger D, Du J, Westermann D, Mohr Z, Sobirey M, Dorenkamp M, Schultheiss HP, Tschöpe C.

Eur J Pharmacol. 2007 Jan 5;554(1):40-5. Epub 2006 Sep 14.PMID: 17097634 [PubMed - indexed for MEDLINE]Related articles

Cardiac function and remodeling is attenuated in transgenic rats expressing the human kallikrein-1 gene after myocardial infarction.

Koch M, Spillmann F, Dendorfer A, Westermann D, Altmann C, Sahabi M, Linthout SV, Bader M, Walther T, Schultheiss HP, Tschöpe C.

Eur J Pharmacol. 2006 Nov 21;550(1-3):143-8. Epub 2006 Sep 7.PMID: 17022964 [PubMed - indexed for MEDLINE]Related articles

Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus.

Westermann D, Rutschow S, Van Linthout S, Linderer A, Bücker-Gärtner C, Sobirey M, Riad A, Pauschinger M, Schultheiss HP, Tschöpe C.

Diabetologia. 2006 Oct;49(10):2507-13. Epub 2006 Aug 26.PMID: 16937126 [PubMed - indexed for MEDLINE]Related articles

Coronary vasospasm-induced acute diastolic dysfunction in a patient with Raynaud's phenomenon.

Tschöpe C, Westermann D, Steendijk P, Kasner M, Rudwaleit M, Schwimmbeck PL, Poller WC, Schultheiss HP.

Clin Res Cardiol. 2006 Jun;95(6):344-8. Epub 2006 May 18.PMID: 16741592 [PubMed - indexed for MEDLINE]Related articles

Coronary vasospasm-induced acute diastolic dysfunction in a patient with Raynaud's phenomenon.

Tschöpe C, Westermann D, Steendijk P, Kasner M, Rudwaleit M, Schwimmbeck PL, Poller WC, Schultheiss HP.

Clin Res Cardiol. 2006 May 18. [Epub ahead of print]PMID: 16699931 [PubMed - as supplied by publisher]Related articles

Sediment and phosphorus transport in irrigation furrows.

Bjorneberg DL, Westermann DT, Aase JK, Clemmens AJ, Strelkoff TS.

J Environ Qual. 2006 Apr 3;35(3):786-94. Print 2006 May-Jun.PMID: 16585621 [PubMed - indexed for MEDLINE]Related articlesFree article

Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy.

Westermann D, Knollmann BC, Steendijk P, Rutschow S, Riad A, Pauschinger M, Potter JD, Schultheiss HP, Tschöpe C.

Eur J Heart Fail. 2006 Mar;8(2):115-21. Epub 2005 Oct 7.PMID: 16214409 [PubMed - indexed for MEDLINE]Related articles

Protection against oxidative stress in diabetic rats: role of angiotensin AT(1) receptor and beta 1-adrenoceptor antagonism.

Dorenkamp M, Riad A, Stiehl S, Spillmann F, Westermann D, Du J, Pauschinger M, Noutsias M, Adams V, Schultheiss HP, Tschöpe C.

Eur J Pharmacol. 2005 Sep 27;520(1-3):179-87.PMID: 16139267 [PubMed - indexed for MEDLINE]Related articles