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    Results: 18

    1.

    Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model.

    Khan MI, Pichna BA, Shi Y, Bowes AJ, Werstuck GH.

    Antioxid Redox Signal. 2009 Sep;11(9):2289-2298.PMID: 19548776 [PubMed - as supplied by publisher]Related articles

    2.

    Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis.

    Bowes AJ, Khan MI, Shi Y, Robertson L, Werstuck GH.

    Am J Pathol. 2009 Jan;174(1):330-42. Epub 2008 Dec 18.PMID: 19095952 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice.

    Zhou J, Werstuck GH, Lhoták S, Shi YY, Tedesco V, Trigatti B, Dickhout J, Majors AK, DiBello PM, Jacobsen DW, Austin RC.

    FASEB J. 2008 Jul;22(7):2569-78. Epub 2008 Mar 25.PMID: 18364397 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Diabetes and cardiovascular disease: explaining the relationship.

    Punthakee Z, Werstuck GH, Gerstein HC.

    Rev Cardiovasc Med. 2007 Summer;8(3):145-53. Review.PMID: 17938614 [PubMed - indexed for MEDLINE]Related articles

    5.

    Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2.

    Colgan SM, Tang D, Werstuck GH, Austin RC.

    Int J Biochem Cell Biol. 2007;39(10):1843-51. Epub 2007 May 16.PMID: 17604677 [PubMed - indexed for MEDLINE]Related articles

    6.

    Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition.

    Shi Y, Gerritsma D, Bowes AJ, Capretta A, Werstuck GH.

    Bioorg Med Chem Lett. 2007 Aug 15;17(16):4491-4. Epub 2007 Jun 6.PMID: 17566732 [PubMed - indexed for MEDLINE]Related articles

    7.

    Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3.

    Robertson LA, Kim AJ, Werstuck GH.

    Can J Physiol Pharmacol. 2006 Jan;84(1):39-48. Review.PMID: 16845889 [PubMed - indexed for MEDLINE]Related articles

    8.

    Glucosamine-induced endoplasmic reticulum dysfunction is associated with accelerated atherosclerosis in a hyperglycemic mouse model.

    Werstuck GH, Khan MI, Femia G, Kim AJ, Tedesco V, Trigatti B, Shi Y.

    Diabetes. 2006 Jan;55(1):93-101.PMID: 16380481 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

    Kim AJ, Shi Y, Austin RC, Werstuck GH.

    J Cell Sci. 2005 Jan 1;118(Pt 1):89-99. Epub 2004 Dec 7.PMID: 15585578 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds.

    Werstuck GH, Kim AJ, Brenstrum T, Ohnmacht SA, Panna E, Capretta A.

    Bioorg Med Chem Lett. 2004 Nov 15;14(22):5465-7.PMID: 15482904 [PubMed - indexed for MEDLINE]Related articles

    11.

    Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease.

    Austin RC, Lentz SR, Werstuck GH.

    Cell Death Differ. 2004 Jul;11 Suppl 1:S56-64. Review.PMID: 15243582 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice.

    Zhou J, Werstuck GH, Lhoták S, de Koning AB, Sood SK, Hossain GS, Møller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, Austin RC.

    Circulation. 2004 Jul 13;110(2):207-13. Epub 2004 Jun 21.PMID: 15210586 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Hyperhomocysteinemia and its role in the development of atherosclerosis.

    Lawrence de Koning AB, Werstuck GH, Zhou J, Austin RC.

    Clin Biochem. 2003 Sep;36(6):431-41. Review.PMID: 12951169 [PubMed - indexed for MEDLINE]Related articles

    14.

    TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia.

    Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG, de Koning AB, Tang D, Wu D, Falk E, Poddar R, Jacobsen DW, Zhang K, Kaufman RJ, Austin RC.

    J Biol Chem. 2003 Aug 8;278(32):30317-27. Epub 2003 May 8.PMID: 12738777 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity.

    Watson LM, Chan AK, Berry LR, Li J, Sood SK, Dickhout JG, Xu L, Werstuck GH, Bajzar L, Klamut HJ, Austin RC.

    J Biol Chem. 2003 May 9;278(19):17438-47. Epub 2003 Mar 5.PMID: 12621026 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.

    Austin RC, Fox JE, Werstuck GH, Stafford AR, Bulman DE, Dally GY, Ackerley CA, Weitz JI, Ray PN.

    J Biol Chem. 2002 Dec 6;277(49):47106-13. Epub 2002 Oct 4.PMID: 12370193 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways.

    Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, Austin RC.

    J Clin Invest. 2001 May;107(10):1263-73.PMID: 11375416 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    An unusual cellular factor potentiates protein-DNA complex assembly between Oct-1 and Vmw65.

    Werstuck GH, Capone JP.

    J Biol Chem. 1993 Jan 15;268(2):1272-8.PMID: 8380410 [PubMed - indexed for MEDLINE]Related articlesFree article

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