PubMed

Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach.

Welsh P, Polisecki E, Robertson M, Jahn S, Buckley BM, de Craen AJ, Ford I, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Hingorani AD, Smith GD, Schaefer E, Sattar N.

J Clin Endocrinol Metab. 2009 Nov 11. [Epub ahead of print]PMID: 19906786 [PubMed - as supplied by publisher]Related articles

NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: Results from the British Women's Heart and Health Study.

Sattar N, Welsh P, Sarwar N, Danesh J, Di Angelantonio E, Gudnason V, Smith GD, Ebrahim S, Lawlor DA.

Atherosclerosis. 2009 Sep 13. [Epub ahead of print]PMID: 19815210 [PubMed - as supplied by publisher]Related articles

Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women.

Jefferis BJ, Whincup P, Welsh P, Wannamethee G, Rumley A, Lennon L, Thomson A, Lawlor D, Carson C, Ebrahim S, Lowe G.

Atherosclerosis. 2009 Aug 19. [Epub ahead of print]PMID: 19748093 [PubMed - as supplied by publisher]Related articles

Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women.

Jefferis BJ, Lowe GD, Welsh P, Rumley A, Lawlor DA, Ebrahim S, Carson C, Doig M, Feyerabend C, McMeekin L, Wannamethee SG, Cook DG, Whincup PH.

Atherosclerosis. 2009 Jul 30. [Epub ahead of print]PMID: 19700161 [PubMed - as supplied by publisher]Related articles

The missing piece in health reform: long-term care.

Souza JC, Welsh PG, DeFriese GH.

N C Med J. 2009 May-Jun;70(3):213-5. No abstract available. PMID: 19653603 [PubMed - in process]Related articles

Lack of effect of TNF{alpha} blockade therapy on circulating adiponectin levels in patients with autoimmune disease: results from two independent prospective studies.

Peters MJ, Watt PH, Cherry L, Welsh P, Henninger E, Dijkmans BA, McInnes IB, Nurmohamed MT, Sattar N.

Ann Rheum Dis. 2009 Jul 28. [Epub ahead of print]PMID: 19640853 [PubMed - as supplied by publisher]Related articles

Associations of circulating TNFalpha and IL-18 with myocardial infarction and cardiovascular risk markers: the Glasgow Myocardial Infarction Study.

Welsh P, Woodward M, Rumley A, Lowe G.

Cytokine. 2009 Aug;47(2):143-7. Epub 2009 Jul 5.PMID: 19581111 [PubMed - indexed for MEDLINE]Related articles

Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?

Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, Cobbe S, de Craen AJ, Lowe GD, Jukema JW, Macfarlane PW, Murphy MB, Stott DJ, Westendorp RG, Shepherd J, Ford I, Packard CJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group.

PLoS Med. 2009 Jun 23;6(6):e1000099. Epub 2009 Jun 23.PMID: 19554082 [PubMed - indexed for MEDLINE]Related articlesFree article

Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10 year cohort study in Glasgow, Scotland.

Woodward M, Welsh P, Rumley A, Tunstall-Pedoe H, Lowe GD.

Eur Heart J. 2009 Apr 10. [Epub ahead of print]PMID: 19363058 [PubMed - as supplied by publisher]Related articles

Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: in vitro comparison of acyclic and macrocyclic ligands.

Hens M, Vaidyanathan G, Welsh P, Zalutsky MR.

Nucl Med Biol. 2009 Feb;36(2):117-28.PMID: 19217523 [PubMed - indexed for MEDLINE]Related articles

Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke.

Welsh P, Barber M, Langhorne P, Rumley A, Lowe GD, Stott DJ.

Cerebrovasc Dis. 2009;27(3):247-53. Epub 2009 Jan 29.PMID: 19176958 [PubMed - indexed for MEDLINE]Related articles

Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis.

Ang DS, Welsh P, Watt P, Nelson SM, Struthers A, Sattar N.

Clin Sci (Lond). 2009 Jun 2;117(1):41-8.PMID: 19175359 [PubMed - indexed for MEDLINE]Related articles

Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke.

Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Lennon LT, Thomson AG, Carson C, Ebrahim S, Lowe GD.

Atherosclerosis. 2009 Jul;205(1):302-8. Epub 2008 Dec 6.PMID: 19135670 [PubMed - indexed for MEDLINE]Related articlesFree article

Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly.

Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, de Craen AJ, Ford I, Forouhi NG, Freeman DJ, Jukema JW, Macfarlane PW, Murphy MB, Packard CJ, Stott DJ, Westendorp RG, Shepherd J; Prospective Study of Pravastatin in Elderly at Risk Trial Study Group.

Diabetologia. 2009 Feb;52(2):235-9. Epub 2008 Nov 22.PMID: 19030842 [PubMed - indexed for MEDLINE]Related articles

Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population.

Welsh P, Murray HM, Buckley BM, de Craen AJ, Ford I, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Sattar N.

Diabetes Care. 2009 Feb;32(2):308-10. Epub 2008 Nov 10.PMID: 19001191 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel antecedent plasma biomarkers of cardiovascular disease: improved evaluation methods and comparator benchmarks raise the bar.

Welsh P, Packard CJ, Sattar N.

Curr Opin Lipidol. 2008 Dec;19(6):563-71. Review.PMID: 18957878 [PubMed - indexed for MEDLINE]Related articles

Adipocytokines and risk of stroke in older people: a nested case-control study.

Stott DJ, Welsh P, Rumley A, Robertson M, Ford I, Sattar N, Westendorp RG, Jukema JW, Cobbe SM, Lowe GD.

Int J Epidemiol. 2009 Feb;38(1):253-61. Epub 2008 Oct 24.PMID: 18952622 [PubMed - indexed for MEDLINE]Related articles

Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men.

Welsh P, Whincup PH, Papacosta O, Wannamethee SG, Lennon L, Thomson A, Rumley A, Lowe GD.

QJM. 2008 Oct;101(10):785-91. Epub 2008 Aug 1.PMID: 18676684 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations of proinflammatory cytokines with the risk of recurrent stroke.

Welsh P, Lowe GD, Chalmers J, Campbell DJ, Rumley A, Neal BC, MacMahon SW, Woodward M.

Stroke. 2008 Aug;39(8):2226-30. Epub 2008 Jun 19.PMID: 18566306 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study.

Welsh P, Woodward M, Rumley A, Lowe G.

Br J Haematol. 2008 Jun;141(6):852-61. Epub 2008 Mar 26.PMID: 18371109 [PubMed - indexed for MEDLINE]Related articles

A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease.

Woodward M, Rumley A, Welsh P, MacMahon S, Lowe G.

J Thromb Haemost. 2007 Sep;5(9):1795-800.PMID: 17723116 [PubMed - indexed for MEDLINE]Related articles

Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis.

Wang X, Feith DJ, Welsh P, Coleman CS, Lopez C, Woster PM, O'Brien TG, Pegg AE.

Carcinogenesis. 2007 Nov;28(11):2404-11. Epub 2007 Aug 3.PMID: 17675337 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentiation of xenografted human fetal lung parenchyma.

Pavlovic J, Floros J, Phelps DS, Wigdahl B, Welsh P, Weisz J, Shearer DA, Leure du Pree A, Myers R, Howett MK.

Early Hum Dev. 2008 Mar;84(3):181-93. Epub 2007 Jun 6.PMID: 17555893 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of flow-through and renewal exposures on the toxicity of copper to rainbow trout.

Welsh PG, Lipton J, Mebane CA, Marr JC.

Ecotoxicol Environ Saf. 2008 Feb;69(2):199-208. Epub 2007 May 22.PMID: 17517436 [PubMed - indexed for MEDLINE]Related articles

An inhibitor of the epidermal growth factor receptor function does not affect the ability of human papillomavirus 11 to form warts in the xenografted immunodeficient mouse model.

Parkinson T, Howett MK, Welsh PA, Patrick SD, Neely EB, Flanagan N, Pollack VA, Pustilnik LR, Moyer J, Perros M.

Antiviral Res. 2007 Apr;74(1):43-50. Epub 2007 Jan 9.PMID: 17239450 [PubMed - indexed for MEDLINE]Related articles

In vitro cytotoxicity of 211At-labeled trastuzumab in human breast cancer cell lines: effect of specific activity and HER2 receptor heterogeneity on survival fraction.

Akabani G, Carlin S, Welsh P, Zalutsky MR.

Nucl Med Biol. 2006 Apr;33(3):333-47. Epub 2006 Mar 9.PMID: 16631082 [PubMed - indexed for MEDLINE]Related articles

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories.

Beer BE, Doncel GF, Krebs FC, Shattock RJ, Fletcher PS, Buckheit RW Jr, Watson K, Dezzutti CS, Cummins JE, Bromley E, Richardson-Harman N, Pallansch LA, Lackman-Smith C, Osterling C, Mankowski M, Miller SR, Catalone BJ, Welsh PA, Howett MK, Wigdahl B, Turpin JA, Reichelderfer P.

Antimicrob Agents Chemother. 2006 Feb;50(2):713-23.PMID: 16436731 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrition and the dining experience in long-term care: critical indicators of nursing home quality of care.

Welsh PG.

N C Med J. 2005 Jul-Aug;66(4):278-82. No abstract available. PMID: 16206531 [PubMed - indexed for MEDLINE]Related articles

Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.

Nisenberg O, Pegg AE, Welsh PA, Keefer K, Shantz LM.

Biochem J. 2006 Jan 1;393(Pt 1):295-302.PMID: 16153183 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced growth of rainbow trout (Oncorhynchus mykiss) fed a live invertebrate diet pre-exposed to metal-contaminated sediments.

Hansen JA, Lipton J, Welsh PG, Cacela D, MacConnell B.

Environ Toxicol Chem. 2004 Aug;23(8):1902-11.PMID: 15352479 [PubMed - indexed for MEDLINE]Related articles

Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells.

Vaidyanathan G, Affleck DJ, Alston KL, Welsh P, Zalutsky MR.

Nucl Med Commun. 2004 Sep;25(9):947-55.PMID: 15319601 [PubMed - indexed for MEDLINE]Related articles

An efficient targeted radiotherapy/gene therapy strategy utilising human telomerase promoters and radioastatine and harnessing radiation-mediated bystander effects.

Boyd M, Mairs RJ, Keith WN, Ross SC, Welsh P, Akabani G, Owens J, Vaidyanathan G, Carruthers R, Dorrens J, Zalutsky MR.

J Gene Med. 2004 Aug;6(8):937-47.PMID: 15293352 [PubMed - indexed for MEDLINE]Related articles

The effect of adjuvant calcium phosphate coating on a porous-coated femoral stem.

Tanzer M, Gollish J, Leighton R, Orrell K, Giacchino A, Welsh P, Shea B, Wells G.

Clin Orthop Relat Res. 2004 Jul;(424):153-60.PMID: 15241158 [PubMed - indexed for MEDLINE]Related articles

The long-term care nursing workforce: who will take care of our rapidly growing aging population?

Welsh PG.

N C Med J. 2004 Mar-Apr;65(2):82-3. No abstract available. PMID: 15239506 [PubMed - indexed for MEDLINE]Related articles

A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells.

Vaidyanathan G, Welsh PC, Vitorello KC, Snyder S, Friedman HS, Zalutsky MR.

Eur J Nucl Med Mol Imaging. 2004 Oct;31(10):1362-70. Epub 2004 Jun 16.PMID: 15205923 [PubMed - indexed for MEDLINE]Related articles

Meta-iodobenzylguanidine derivatives containing a second guanidine moiety.

Vaidyanathan G, Shankar S, Affleck DJ, Alston K, Norman J, Welsh P, LeGrand H, Zalutsky MR.

Bioorg Med Chem. 2004 Apr 1;12(7):1649-56.PMID: 15028258 [PubMed - indexed for MEDLINE]Related articles

O6-3-[131I]iodobenzylguanine: improved synthesis and further evaluation of a potential agent for imaging of alkylguanine-DNA alkyltransferase.

Vaidyanathan G, Affleck DJ, Norman J, Welsh P, Liu W, Johnson SP, Friedman HS, Zalutsky MR.

Bioconjug Chem. 2004 Mar-Apr;15(2):402-8.PMID: 15025538 [PubMed - indexed for MEDLINE]Related articles

HIV-1 infection in a small animal human vaginal xenograft model.

Kish TM, Ward MG, Welsh PA, Budgeon LR, Wigdahl B, Howett MK.

J Acquir Immune Defic Syndr. 2003 Dec 15;34(5):454-60.PMID: 14657754 [PubMed - indexed for MEDLINE]Related articles

Suppression of human papillomavirus gene expression in vitro and in vivo by herpes simplex virus type 2 infection.

Fang L, Ward MG, Welsh PA, Budgeon LR, Neely EB, Howett MK.

Virology. 2003 Sep 15;314(1):147-60.PMID: 14517068 [PubMed - indexed for MEDLINE]Related articles

A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease.

Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ.

J Am Coll Cardiol. 2003 Mar 19;41(6):961-5. Erratum in: J Am Coll Cardiol. 2006 Nov 7;48(9):1918. PMID: 12651041 [PubMed - indexed for MEDLINE]Related articles

N-succinimidyl 3-[(131)I]iodo-4-phosphonomethylbenzoate ([(131)I]SIPMB), a negatively charged substituent-bearing acylation agent for the radioiodination of peptides and mAbs.

Shankar S, Vaidyanathan G, Affleck D, Welsh PC, Zalutsky MR.

Bioconjug Chem. 2003 Mar-Apr;14(2):331-41.PMID: 12643743 [PubMed - indexed for MEDLINE]Related articles

Sodium-iodide symporter (NIS)-mediated accumulation of [(211)At]astatide in NIS-transfected human cancer cells.

Carlin S, Mairs RJ, Welsh P, Zalutsky MR.

Nucl Med Biol. 2002 Oct;29(7):729-39.PMID: 12381453 [PubMed - indexed for MEDLINE]Related articles

The crisis in long-term care. Finding and retaining our direct care workers.

Souza C, Welsh PG.

N C Med J. 2002 Mar-Apr;63(2):110-1. No abstract available. PMID: 12063901 [PubMed - indexed for MEDLINE]Related articles

Relationship between exposure duration, tissue residues, growth, and mortality in rainbow trout (Oncorhynchus mykiss) juveniles sub-chronically exposed to copper.

Hansen JA, Lipton J, Welsh PG, Morris J, Cacela D, Suedkamp MJ.

Aquat Toxicol. 2002 Aug;58(3-4):175-88.PMID: 12007873 [PubMed - indexed for MEDLINE]Related articles

The effects of long-term cadmium exposure on the growth and survival of juvenile bull trout (Salvelinus confluentus).

Hansen JA, Welsh PG, Lipton J, Suedkamp MJ.

Aquat Toxicol. 2002 Aug;58(3-4):165-74.PMID: 12007872 [PubMed - indexed for MEDLINE]Related articles

PRO_SELECT: combining structure-based drug design and array-based chemistry for rapid lead discovery. 2. The development of a series of highly potent and selective factor Xa inhibitors.

Liebeschuetz JW, Jones SD, Morgan PJ, Murray CW, Rimmer AD, Roscoe JM, Waszkowycz B, Welsh PM, Wylie WA, Young SC, Martin H, Mahler J, Brady L, Wilkinson K.

J Med Chem. 2002 Mar 14;45(6):1221-32.PMID: 11881991 [PubMed - indexed for MEDLINE]Related articles

Relative sensitivity of bull trout (Salvelinus confluentus) and rainbow trout (Oncorhynchus mykiss) to acute copper toxicity.

Hansen JA, Lipton J, Welsh PG.

Environ Toxicol Chem. 2002 Mar;21(3):633-9.PMID: 11878477 [PubMed - indexed for MEDLINE]Related articles

Relative sensitivity of bull trout (Salvelinus confluentus) and rainbow trout (Oncorhynchus mykiss) to acute exposures of cadmium and zinc.

Hansen JA, Welsh PG, Lipton J, Cacela D, Dailey AD.

Environ Toxicol Chem. 2002 Jan;21(1):67-75.PMID: 11804063 [PubMed - indexed for MEDLINE]Related articles

Immunological characterization of human vaginal xenografts in immunocompromised mice: development of a small animal model for the study of human immunodeficiency virus-1 infection.

Kish TM, Budgeon LR, Welsh PA, Howett MK.

Am J Pathol. 2001 Dec;159(6):2331-45.PMID: 11733382 [PubMed - indexed for MEDLINE]Related articlesFree article

Positively charged templates for labeling internalizing antibodies: comparison of N-succinimidyl 5-iodo-3-pyridinecarboxylate and the D-amino acid peptide KRYRR.

Foulon CF, Welsh PC, Bigner DD, Zalutsky MR.

Nucl Med Biol. 2001 Oct;28(7):769-77.PMID: 11578897 [PubMed - indexed for MEDLINE]Related articles