PubMed

Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes.

Mokhtari D, Welsh N.

Clin Sci (Lond). 2009 Nov 9;118(4):241-7.PMID: 19886867 [PubMed - in process]Related articles

Overexpression of the Nuclear Factor-{kappa}B subunit c-Rel protects against human islet cell death in vitro.

Mokhtari D, Barbu A, Mehmeti I, Vercamer C, Welsh N.

Am J Physiol Endocrinol Metab. 2009 Aug 25. [Epub ahead of print]PMID: 19706790 [PubMed - as supplied by publisher]Related articles

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice.

Mokhtari D, Kerblom B, Mehmeti I, Wang X, Funa NS, Olerud J, Lenzen S, Welsh N, Welsh M.

Biochem Biophys Res Commun. 2009 Sep 25;387(3):553-7. Epub 2009 Jul 15.PMID: 19615333 [PubMed - indexed for MEDLINE]Related articles

The lived experience of alopecia areata: a qualitative study.

Welsh N, Guy A.

Body Image. 2009 Jun;6(3):194-200. Epub 2009 May 5.PMID: 19409867 [PubMed - indexed for MEDLINE]Related articles

Antiapoptotic small interfering RNA as potent adjuvant of DNA vaccination in a mouse mammary tumor model.

Dharmapuri S, Aurisicchio L, Biondo A, Welsh N, Ciliberto G, La Monica N.

Hum Gene Ther. 2009 Jun;20(6):589-97.PMID: 19222350 [PubMed - indexed for MEDLINE]Related articles

Detailed transcriptome atlas of the pancreatic beta cell.

Kutlu B, Burdick D, Baxter D, Rasschaert J, Flamez D, Eizirik DL, Welsh N, Goodman N, Hood L.

BMC Med Genomics. 2009 Jan 15;2:3.PMID: 19146692 [PubMed - in process]Related articlesFree article

Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function.

Sandler S, Andersson AK, Larsson J, Makeeva N, Olsen T, Arkhammar PO, Hansen JB, Karlsson FA, Welsh N.

Biochem Pharmacol. 2008 Dec 15;76(12):1748-56. Epub 2008 Sep 10.PMID: 18831966 [PubMed - indexed for MEDLINE]Related articles

The importance of RNA binding proteins in preproinsulin mRNA stability.

Fred RG, Welsh N.

Mol Cell Endocrinol. 2009 Jan 15;297(1-2):28-33. Epub 2008 Jun 21. Review.PMID: 18621093 [PubMed - indexed for MEDLINE]Related articles

Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets.

Olerud J, Johansson M, Lawler J, Welsh N, Carlsson PO.

Diabetes. 2008 Jul;57(7):1870-7. Epub 2008 Apr 16.PMID: 18420490 [PubMed - indexed for MEDLINE]Related articlesFree article

MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells.

Mokhtari D, Myers JW, Welsh N.

Diabetes. 2008 Jul;57(7):1896-904. Epub 2008 Apr 16.PMID: 18420486 [PubMed - indexed for MEDLINE]Related articlesFree article

The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death.

Mokhtari D, Myers JW, Welsh N.

Endocrinology. 2008 Jun;149(6):3046-53. Epub 2008 Feb 28.PMID: 18308848 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of PTB in insulin mRNA stability control.

Fred RG, Tillmar L, Welsh N.

Curr Diabetes Rev. 2006 Aug;2(3):363-6. Review.PMID: 18220641 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta-activated protein kinase 1-binding protein (TAB)-1alpha, but not TAB1beta, mediates cytokine-induced p38 mitogen-activated protein kinase phosphorylation and cell death in insulin-producing cells.

Makeeva N, Roomans GM, Myers JW, Welsh N.

Endocrinology. 2008 Jan;149(1):302-9. Epub 2007 Oct 11.PMID: 17932218 [PubMed - indexed for MEDLINE]Related articlesFree article

Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet.

Hägerkvist R, Jansson L, Welsh N.

Clin Sci (Lond). 2008 Jan;114(1):65-71.PMID: 17868036 [PubMed - indexed for MEDLINE]Related articles

Claes Hellerström: a friendly islet explorer.

Andersson A, Eriksson UJ, Jansson L, Sandler S, Welsh M, Welsh N.

Diabetologia. 2007 Feb;50(2):4 p following 496. No abstract available. PMID: 17823989 [PubMed - indexed for MEDLINE]Related articles

Lipofection of insulin-producing RINm5F cells: methodological improvements.

Barbu A, Welsh N.

J Liposome Res. 2007;17(2):49-62.PMID: 17613696 [PubMed - indexed for MEDLINE]Related articles

Role of TAB1 in nitric oxide-induced p38 activation in insulin-producing cells.

Makeeva N, Roomans GM, Welsh N.

Int J Biol Sci. 2006 Nov 25;3(2):71-6.PMID: 17205106 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.

Hägerkvist R, Sandler S, Mokhtari D, Welsh N.

FASEB J. 2007 Feb;21(2):618-28. Epub 2006 Nov 29.PMID: 17135364 [PubMed - indexed for MEDLINE]Related articlesFree article

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli.

Hägerkvist R, Mokhtari D, Lindholm C, Farnebo F, Mostoslavsky G, Mulligan RC, Welsh N, Welsh M.

Exp Cell Res. 2007 Jan 15;313(2):284-91. Epub 2006 Oct 24.PMID: 17112510 [PubMed - indexed for MEDLINE]Related articles

Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro.

Hägerkvist R, Makeeva N, Elliman S, Welsh N.

Cell Biol Int. 2006 Dec;30(12):1013-7. Epub 2006 Sep 3.PMID: 17020808 [PubMed - indexed for MEDLINE]Related articles

A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans.

Barbu AR, Bodin B, Welsh M, Jansson L, Welsh N.

Diabetologia. 2006 Oct;49(10):2388-91. Epub 2006 Aug 30.PMID: 16944093 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.

Cnop M, Welsh N, Jonas JC, Jörns A, Lenzen S, Eizirik DL.

Diabetes. 2005 Dec;54 Suppl 2:S97-107. Review.PMID: 16306347 [PubMed - indexed for MEDLINE]Related articlesFree article

Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL.

Diabetes. 2005 Nov;54(11):3238-44.PMID: 16249450 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells.

Makeeva N, Myers JW, Welsh N.

Biochem J. 2006 Jan 1;393(Pt 1):129-39.PMID: 16097952 [PubMed - indexed for MEDLINE]Related articlesFree article

siRNA produced by recombinant dicer mediates efficient gene silencing in islet cells.

Hägerkvist R, Mokhtari D, Myers JW, Tengholm A, Welsh N.

Ann N Y Acad Sci. 2005 Apr;1040:114-22.PMID: 15891014 [PubMed - indexed for MEDLINE]Related articles

Effective and accurate screening for diabetic retinopathy using a 60 degree mydriatic fundus camera.

Carmichael TR, Carp GI, Welsh ND, Kalk WJ.

S Afr Med J. 2005 Jan;95(1):57-61.PMID: 15762251 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenoviral-mediated transduction of human pancreatic islets: importance of adenoviral genome for cell viability and association with a deficient antiviral response.

Barbu AR, Akusjärvi G, Welsh N.

Endocrinology. 2005 May;146(5):2406-14. Epub 2005 Feb 10.PMID: 15705772 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of polypyrimidine tract binding protein results in higher insulin mRNA levels.

Fred RG, Welsh N.

Biochem Biophys Res Commun. 2005 Mar 4;328(1):38-42.PMID: 15670747 [PubMed - indexed for MEDLINE]Related articles

The use of tetrazolium salt-based methods for determination of islet cell viability in response to cytokines: a cautionary note.

Barbu A, Welsh N.

Diabetologia. 2004 Nov;47(11):2042-3. Epub 2004 Dec 1. No abstract available. PMID: 15599703 [PubMed - indexed for MEDLINE]Related articles

Promoting islet cell function after transplantation.

Andersson A, Carlsson PO, Carlsson C, Olsson R, Nordin A, Johansson M, Palm F, Tyrberg B, Källskog O, Tillmar L, Welsh N, Mattsson G, Jansson L.

Cell Biochem Biophys. 2004;40(3 Suppl):55-64. Review.PMID: 15289643 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin.

Tillmar L, Welsh N.

Mol Cell Biochem. 2004 May;260(1-2):85-90.PMID: 15228089 [PubMed - indexed for MEDLINE]Related articles

p38 MAPK inhibits JNK2 and mediates cytokine-activated iNOS induction and apoptosis independently of NF-KB translocation in insulin-producing cells.

Saldeen J, Welsh N.

Eur Cytokine Netw. 2004 Jan-Mar;15(1):47-52.PMID: 15217752 [PubMed - indexed for MEDLINE]Related articles

In vitro cultured rat islets express genes that both prevent and promote angiogenesis.

Tillmar L, Welsh N.

JOP. 2004 Mar;5(2):81-91.PMID: 15007189 [PubMed - indexed for MEDLINE]Related articlesFree article

Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis.

Lehtihet M, Welsh N, Berggren PO, Cook GA, Sjoholm A.

Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E438-46. Epub 2003 Apr 8.PMID: 12684219 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1beta mediated suppression--possible involvement of the mitochondrial membrane potential.

Kullin M, Li Z, Bondo Hansen J, Welsh N, Karlsson FA, Sandler S.

Diabetologia. 2003 Jan;46(1):80-8. Epub 2003 Jan 11.PMID: 12637986 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis.

Saldeen J, Tillmar L, Karlsson E, Welsh N.

Mol Cell Biochem. 2003 Jan;243(1-2):113-22.PMID: 12619896 [PubMed - indexed for MEDLINE]Related articles

Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression.

Barbu AR, Akusjärvi G, Welsh N.

Mol Med. 2002 Nov;8(11):733-41.PMID: 12520090 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.

Welsh N, Makeeva N, Welsh M.

Mol Med. 2002 Nov;8(11):695-704.PMID: 12520086 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the time course for organ culture-induced endothelin ET B receptor upregulation in rat mesenteric arteries.

Möller S, Uddman E, Welsh N, Edvinsson L, Adner M.

Eur J Pharmacol. 2002 Nov 15;454(2-3):209-15.PMID: 12421649 [PubMed - indexed for MEDLINE]Related articles

Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich insulin mRNA 3'-untranslated region.

Tillmar L, Welsh N.

Mol Med. 2002 May;8(5):263-72.PMID: 12359957 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.

Barbu A, Welsh N, Saldeen J.

Mol Cell Endocrinol. 2002 Apr 25;190(1-2):75-82.PMID: 11997180 [PubMed - indexed for MEDLINE]Related articles

Pharmacological characterization of cholecystokinin receptors mediating contraction of human gallbladder and ascending colon.

Morton MF, Welsh NJ, Tavares IA, Shankley NP.

Regul Pept. 2002 Apr 15;105(1):59-64.PMID: 11853872 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular disease risk stratification and comparison in a California population.

Lin Z, Meng YY, Leung KM, Jatulis DE, Welsh NJ, Zaher CA, Legorreta AP.

Prev Cardiol. 2001 Winter;4(1):9-15.PMID: 11828193 [PubMed - as supplied by publisher]Related articles

Gene therapy in diabetes mellitus: promises and piffalls.

Welsh N.

Curr Opin Mol Ther. 1999 Aug;1(4):464-70. Review.PMID: 11713761 [PubMed - indexed for MEDLINE]Related articles

Control of insulin mRNA stability in rat pancreatic islets. Regulatory role of a 3'-untranslated region pyrimidine-rich sequence.

Tillmar L, Carlsson C, Welsh N.

J Biol Chem. 2002 Jan 11;277(2):1099-106. Epub 2001 Nov 5.PMID: 11696543 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis.

Saldeen J, Lee JC, Welsh N.

Biochem Pharmacol. 2001 Jun 15;61(12):1561-9.PMID: 11377386 [PubMed - indexed for MEDLINE]Related articles

Absence of a significant linkage between Na(+),K(+)-ATPase subunit (ATP1A3 and ATP1B3) genotypes and bipolar affective disorder in the old-order Amish.

Philibert RA, Cheung D, Welsh N, Damschroder-Williams P, Thiel B, Ginns EI, Gershenfeld HK.

Am J Med Genet. 2001 Apr 8;105(3):291-4.PMID: 11353452 [PubMed - indexed for MEDLINE]Related articles

Inhibition of gastric acid secretion by nimesulide: a possible factor in its gastric tolerability.

Tavares IA, Borrelli F, Welsh NJ.

Clin Exp Rheumatol. 2001;19(1 Suppl 22):S13-5.PMID: 11296543 [PubMed - indexed for MEDLINE]Related articles

The acid sphingomyelinase inhibitor SR33557 counteracts TNF-alpha-mediated potentiation of IL-1beta-induced NF-kappaB activation in the insulin-producing cell line Rinm5F.

Saldeen J, Jaffrézou JP, Welsh N.

Autoimmunity. 2000 Dec;32(4):241-54.PMID: 11191283 [PubMed - indexed for MEDLINE]Related articles

Novel experimental strategies to prevent the development of type 1 diabetes mellitus.

Sandler S, Andersson AK, Barbu A, Hellerström C, Holstad M, Karlsson E, Sandberg JO, Strandell E, Saldeen J, Sternesjö J, Tillmar L, Eizirik DL, Flodström M, Welsh N.

Ups J Med Sci. 2000;105(2):17-34. Review.PMID: 11095103 [PubMed - indexed for MEDLINE]Related articles