PubMed

Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.

Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW 2nd, Weissleder R, Josephson L, Rosenzweig A.

Circ Cardiovasc Imaging. 2009 Nov;2(6):468-75. Epub 2009 Sep 1.PMID: 19920045 [PubMed - in process]Related articles

Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia.

Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L.

Circ Cardiovasc Imaging. 2009 Nov;2(6):460-7. Epub 2009 Sep 29.PMID: 19920044 [PubMed - in process]Related articlesFree article

A wortmannin-cetuximab as a double drug.

Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L.

Bioconjug Chem. 2009 Nov;20(11):2185-9.PMID: 19883074 [PubMed - in process]Related articles

Near-infrared fluorescence: application to in vivo molecular imaging.

Hilderbrand SA, Weissleder R.

Curr Opin Chem Biol. 2009 Oct 29. [Epub ahead of print]PMID: 19879798 [PubMed - as supplied by publisher]Related articles

Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1.

Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B.

Mol Ther. 2009 Oct 20. [Epub ahead of print]PMID: 19844198 [PubMed - as supplied by publisher]Related articles

18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis.

Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R.

JACC Cardiovasc Imaging. 2009 Oct;2(10):1213-22.PMID: 19833312 [PubMed - in process]Related articlesFree article

Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis.

Salthouse CD, Weissleder R, Mahmood U.

IEEE Trans Biomed Circuits Syst. 2008 Sep 1;2(3):204-211.PMID: 19830273 [PubMed]Free article

Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation.

Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA.

J Am Chem Soc. 2009 Nov 4;131(43):15739-44.PMID: 19817443 [PubMed - in process]Related articlesFree article

Self-assembled multifunctional Fe/MgO nanospheres for magnetic resonance imaging and hyperthermia.

Martinez-Boubeta C, Balcells L, Cristòfol R, Sanfeliu C, Rodríguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martínez B.

Nanomedicine. 2009 Oct 2. [Epub ahead of print]PMID: 19800988 [PubMed - as supplied by publisher]Related articles

Enhancing navigation in biomedical databases by community voting and database-driven text classification.

Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R.

BMC Bioinformatics. 2009 Oct 3;10:317.PMID: 19799796 [PubMed - in process]Related articlesFree article

Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study.

Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E.

Tissue Eng Part C Methods. 2009 Sep 14. [Epub ahead of print]PMID: 19751103 [PubMed - as supplied by publisher]Related articles

Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles.

Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R.

Opt Lett. 2009 Sep 1;34(17):2566-8. doi: 10.1364/OL.34.002566.PMID: 19724491 [PubMed - in process]Related articlesFree article

MRI of a novel murine working heart transplant model.

Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R.

Circ Heart Fail. 2009 May;2(3):272-4. No abstract available. PMID: 19718275 [PubMed - indexed for MEDLINE]Related articlesFree article

Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition.

Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R.

Angew Chem Int Ed Engl. 2009;48(38):7013-6. No abstract available. PMID: 19697389 [PubMed - in process]Related articles

Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila.

Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R.

J Vis Exp. 2009 Aug 20;(30). pii: 1510. doi: 10.3791/1510.PMID: 19696720 [PubMed - indexed for MEDLINE]Related articlesFree article

High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins.

McCarthy JR, Bhaumik J, Merbouh N, Weissleder R.

Org Biomol Chem. 2009 Sep 7;7(17):3430-6. Epub 2009 Jul 2.PMID: 19675897 [PubMed - in process]Related articlesFree article

Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaques.

Ronald JA, Chen JW, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK.

Circulation. 2009 Aug 18;120(7):592-9. Epub 2009 Aug 3.PMID: 19652086 [PubMed - indexed for MEDLINE]Related articlesFree article

Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.

Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U.

Arthritis Rheum. 2009 Aug;60(8):2314-24.PMID: 19644878 [PubMed - indexed for MEDLINE]Related articles

Identification of splenic reservoir monocytes and their deployment to inflammatory sites.

Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ.

Science. 2009 Jul 31;325(5940):612-6.PMID: 19644120 [PubMed - indexed for MEDLINE]Related articles

Rapid detection and profiling of cancer cells in fine-needle aspirates.

Lee H, Yoon TJ, Figueiredo JL, Swirski FK, Weissleder R.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12459-64. Epub 2009 Jul 20.PMID: 19620715 [PubMed - indexed for MEDLINE]Related articles

Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers.

Bhaumik J, Weissleder R, McCarthy JR.

J Org Chem. 2009 Jul 17. [Epub ahead of print]PMID: 19610602 [PubMed - as supplied by publisher]Related articles

Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.

Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1444-51. Epub 2009 Jul 16.PMID: 19608968 [PubMed - indexed for MEDLINE]Related articles

A DNA-binding Gd chelate for the detection of cell death by MRI.

Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L.

Chem Commun (Camb). 2009 Aug 7;(29):4444-6. Epub 2009 Jun 12.PMID: 19597620 [PubMed - indexed for MEDLINE]Related articlesFree article

Upconverting luminescent nanomaterials: application to in vivo bioimaging.

Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R.

Chem Commun (Camb). 2009 Jul 28;(28):4188-90. Epub 2009 Jun 12.PMID: 19585016 [PubMed - indexed for MEDLINE]Related articlesFree article

Born normalization for fluorescence optical projection tomography for whole heart imaging.

Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R.

J Vis Exp. 2009 Jun 2;(28). pii: 1389. doi: 10.3791/1389.PMID: 19578329 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear microscopy: a novel technique for quantitative imaging of gadolinium distribution within tissue sections.

Rajendran R, Ronald JA, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F.

Microsc Microanal. 2009 Aug;15(4):338-44.PMID: 19575834 [PubMed - indexed for MEDLINE]Related articles

Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy.

Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M.

Clin Imaging. 2009 Jul-Aug;33(4):301-5.PMID: 19559353 [PubMed - indexed for MEDLINE]Related articles

Ultrasensitive detection of bacteria using core-shell nanoparticles and an NMR-filter system.

Lee H, Yoon TJ, Weissleder R.

Angew Chem Int Ed Engl. 2009;48(31):5657-60. No abstract available. PMID: 19554581 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.

Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG.

Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):1207-16.PMID: 19545786 [PubMed - indexed for MEDLINE]Related articlesFree article

On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA).

Vonken EJ, Korosoglou G, Yu J, Schär M, Weissleder R, Stuber M.

Magn Reson Med. 2009 Aug;62(2):314-24.PMID: 19526511 [PubMed - indexed for MEDLINE]Related articlesFree article

A stabilized demethoxyviridin derivative inhibits PI3 kinase.

Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4223-7. Epub 2009 May 30.PMID: 19523825 [PubMed - in process]Related articles

The antiproliferative cytostatic effects of a self-activating viridin prodrug.

Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L.

Mol Cancer Ther. 2009 Jun;8(6):1666-75. Epub 2009 Jun 9.PMID: 19509266 [PubMed - indexed for MEDLINE]Related articles

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.

Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski FK.

PLoS One. 2009 May 22;4(5):e5663.PMID: 19461894 [PubMed - indexed for MEDLINE]Related articlesFree article

Multimodal nanoagents for the detection of intravascular thrombi.

McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA.

Bioconjug Chem. 2009 Jun;20(6):1251-5.PMID: 19456115 [PubMed - indexed for MEDLINE]Related articlesFree article

Implantable diagnostic device for cancer monitoring.

Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ.

Biosens Bioelectron. 2009 Jul 15;24(11):3252-7. Epub 2009 Apr 16.PMID: 19442510 [PubMed - indexed for MEDLINE]Related articles

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle.

Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton AP, Waterman P, Figueiredo JL, Kohler RH, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ.

Neoplasia. 2009 May;11(5):459-68, 2 p following 468.PMID: 19412430 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetically engineered T cells to target EGFRvIII expressing glioblastoma.

Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS.

J Neurooncol. 2009 Sep;94(3):373-82. Epub 2009 Apr 23.PMID: 19387557 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis.

Swirski FK, Weissleder R, Pittet MJ.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1424-32. Epub 2009 Apr 16. Review.PMID: 19372462 [PubMed - indexed for MEDLINE]Related articles

Optical and multimodality molecular imaging: insights into atherosclerosis.

Jaffer FA, Libby P, Weissleder R.

Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1017-24. Epub 2009 Apr 9. Review.PMID: 19359659 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular imaging of innate immune cell function in transplant rejection.

Christen T, Nahrendorf M, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P.

Circulation. 2009 Apr 14;119(14):1925-32. Epub 2009 Mar 30.PMID: 19332470 [PubMed - indexed for MEDLINE]Related articlesFree article

Nanoparticle-target interactions parallel antibody-protein interactions.

Koh I, Hong R, Weissleder R, Josephson L.

Anal Chem. 2009 May 1;81(9):3618-22.PMID: 19323458 [PubMed - indexed for MEDLINE]Related articles

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R.

Circulation. 2009 Apr 7;119(13):1785-94. Epub 2009 Mar 23.PMID: 19307473 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy.

Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K.

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4822-7. Epub 2009 Mar 5.PMID: 19264968 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutant sodium channel for tumor therapy.

Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, García-Añoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO.

Mol Ther. 2009 May;17(5):810-9. Epub 2009 Mar 3.PMID: 19259066 [PubMed - indexed for MEDLINE]Related articlesFree article

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.

Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2712-6. Epub 2009 Feb 5.PMID: 19196966 [PubMed - indexed for MEDLINE]Related articlesFree article

Normalized Born ratio for fluorescence optical projection tomography.

Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R.

Opt Lett. 2009 Feb 1;34(3):319-21.PMID: 19183644 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.

McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW.

Neuroimage. 2009 Apr 1;45(2):360-9. Epub 2008 Dec 25.PMID: 19154791 [PubMed - indexed for MEDLINE]Related articlesFree article

18F labeled nanoparticles for in vivo PET-CT imaging.

Devaraj NK, Keliher EJ, Thurber GM, Nahrendorf M, Weissleder R.

Bioconjug Chem. 2009 Feb;20(2):397-401.PMID: 19138113 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.

Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U.

Gynecol Oncol. 2009 Mar;112(3):616-22. Epub 2009 Jan 8.PMID: 19135233 [PubMed - indexed for MEDLINE]Related articles

Design and demonstration of a small-animal up-conversion imager.

Salthouse C, Hildebrand S, Weissleder R, Mahmood U.

Opt Express. 2008 Dec 22;16(26):21731-7.PMID: 19104605 [PubMed - indexed for MEDLINE]Related articlesFree article