PubMed

PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.

Weinman EJ, Steplock D, Cha B, Kovbasnjuk O, Frost NA, Cunningham R, Shenolikar S, Blanpied TA, Donowitz M.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1560-5. Epub 2009 Sep 30.PMID: 19794105 [PubMed - in process]Related articles

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.

Singh AK, Riederer B, Krabbenhöft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler U.

J Clin Invest. 2009 Mar;119(3):540-50. doi: 10.1172/JCI35541. Epub 2009 Feb 16.PMID: 19221439 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells.

Cunningham R, Biswas R, Brazie M, Steplock D, Shenolikar S, Weinman EJ.

Am J Physiol Renal Physiol. 2009 Feb;296(2):F355-61. Epub 2008 Nov 5.PMID: 18987113 [PubMed - indexed for MEDLINE]Related articles

The ROMK potassium channel is present in mammalian urinary tract epithelia and muscle.

Spector DA, Yang Q, Klopouh L, Deng J, Weinman EJ, Steplock DA, Biswas R, Brazie MF, Liu J, Wade JB.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1658-65. Epub 2008 Sep 17.PMID: 18799551 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.

Broere N, Chen M, Cinar A, Singh AK, Hillesheim J, Riederer B, Lünnemann M, Rottinghaus I, Krabbenhöft A, Engelhardt R, Rausch B, Weinman EJ, Donowitz M, Hubbard A, Kocher O, de Jonge HR, Hogema BM, Seidler U.

Pflugers Arch. 2009 Mar;457(5):1079-91. Epub 2008 Aug 29.PMID: 18758809 [PubMed - indexed for MEDLINE]Related articles

Cholesterol embolization syndrome induced by thrombolytic therapy.

Hitti WA, Wali RK, Weinman EJ, Drachenberg C, Briglia A.

Am J Cardiovasc Drugs. 2008;8(1):27-34. Review. Erratum in: Am J Cardiovasc Drugs. 2008;8(6):427. Weiman, Edward J [corrected to Weinman, Edward J]. PMID: 18303935 [PubMed - indexed for MEDLINE]Related articles

Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.

Cunningham R, Esmaili A, Brown E, Biswas RS, Murtazina R, Donowitz M, Dijkman HB, van der Vlag J, Hogema BM, De Jonge HR, Shenolikar S, Wade JB, Weinman EJ.

Am J Physiol Renal Physiol. 2008 Apr;294(4):F1001-7. Epub 2008 Feb 6.PMID: 18256311 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel regulatory function for NHERF-1 in Npt2a transcription.

Khundmiri SJ, Ahmad A, Bennett RE, Weinman EJ, Steplock D, Cole J, Baumann PD, Lewis J, Singh S, Clark BJ, Lederer ED.

Am J Physiol Renal Physiol. 2008 Apr;294(4):F840-9. Epub 2008 Jan 23.PMID: 18216150 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.

Pan Y, Weinman EJ, Dai JL.

Breast Cancer Res. 2008;10(1):R5. Epub 2008 Jan 11.PMID: 18190691 [PubMed - indexed for MEDLINE]Related articlesFree article

Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.

Weinman EJ, Biswas RS, Peng G, Shen L, Turner CL, E X, Steplock D, Shenolikar S, Cunningham R.

J Clin Invest. 2007 Nov;117(11):3412-20. Erratum in: J Clin Invest. 2008 Jan;118(1):387. Peng, Quihong [corrected to Peng, Guihong]. PMID: 17975671 [PubMed - indexed for MEDLINE]Related articlesFree article

Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.

Broere N, Hillesheim J, Tuo B, Jorna H, Houtsmuller AB, Shenolikar S, Weinman EJ, Donowitz M, Seidler U, de Jonge HR, Hogema BM.

J Biol Chem. 2007 Dec 28;282(52):37575-84. Epub 2007 Oct 18.PMID: 17947234 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.

Voltz JW, Brush M, Sikes S, Steplock D, Weinman EJ, Shenolikar S.

J Biol Chem. 2007 Nov 16;282(46):33879-87. Epub 2007 Sep 25. Erratum in: J Biol Chem. 2008 Feb 15;283(7):4459. PMID: 17895247 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-matrix interactions modulate transepithelial phosphate transport in P(i)-deprived OK cells.

Barac-Nieto M, Weinman EJ, Spitzer A.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1272-7. Epub 2007 Jul 25.PMID: 17652432 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.

Murtazina R, Kovbasnjuk O, Zachos NC, Li X, Chen Y, Hubbard A, Hogema BM, Steplock D, Seidler U, Hoque KM, Tse CM, De Jonge HR, Weinman EJ, Donowitz M.

J Biol Chem. 2007 Aug 24;282(34):25141-51. Epub 2007 Jun 19.PMID: 17580307 [PubMed - indexed for MEDLINE]Related articlesFree article

Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.

Cunningham R, Brazie M, Kanumuru S, E X, Biswas R, Wang F, Steplock D, Wade JB, Anzai N, Endou H, Shenolikar S, Weinman EJ.

J Am Soc Nephrol. 2007 May;18(5):1419-25. Epub 2007 Apr 4.PMID: 17409311 [PubMed - indexed for MEDLINE]Related articlesFree article

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, Azzariti A, Mangia A, Paradiso A, Reshkin SJ.

Mol Biol Cell. 2007 May;18(5):1768-80. Epub 2007 Mar 1.PMID: 17332506 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute renal failure and nephrotic range proteinuria due to amyloidosis in an HIV-infected patient.

Chan-Tack KM, Ahuja N, Weinman EJ, Wali RK, Uche A, Greisman LA, Drachenberg C, Hawkins PN, Redfield RR.

Am J Med Sci. 2006 Dec;332(6):364-7.PMID: 17170630 [PubMed - indexed for MEDLINE]Related articles

Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice.

Capuano P, Bacic D, Roos M, Gisler SM, Stange G, Biber J, Kaissling B, Weinman EJ, Shenolikar S, Wagner CA, Murer H.

Am J Physiol Cell Physiol. 2007 Feb;292(2):C927-34. Epub 2006 Sep 20.PMID: 16987995 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.

Cunningham R, Steplock D, E X, Biswas RS, Wang F, Shenolikar S, Weinman EJ.

Am J Physiol Renal Physiol. 2006 Oct;291(4):F896-901. Epub 2006 May 16.PMID: 16705152 [PubMed - indexed for MEDLINE]Related articlesFree article

The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.

Weinman EJ, Hall RA, Friedman PA, Liu-Chen LY, Shenolikar S.

Annu Rev Physiol. 2006;68:491-505. Review.PMID: 16460281 [PubMed - indexed for MEDLINE]Related articles

Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice.

Weinman EJ, Mohanlal V, Stoycheff N, Wang F, Steplock D, Shenolikar S, Cunningham R.

Am J Physiol Renal Physiol. 2006 Apr;290(4):F838-43. Epub 2005 Oct 25. Erratum in: Am J Physiol Renal Physiol. 2006 Jul;291(1):F254-5. PMID: 16249272 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.

Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola V.

J Biol Chem. 2005 Dec 9;280(49):40925-33. Epub 2005 Oct 3.PMID: 16203733 [PubMed - indexed for MEDLINE]Related articlesFree article

Parathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells.

Khundmiri SJ, Weinman EJ, Steplock D, Cole J, Ahmad A, Baumann PD, Barati M, Rane MJ, Lederer E.

J Am Soc Nephrol. 2005 Sep;16(9):2598-607. Epub 2005 Jul 6.PMID: 16000700 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.

Cunningham R, E X, Steplock D, Shenolikar S, Weinman EJ.

Am J Physiol Renal Physiol. 2005 Oct;289(4):F933-8. Epub 2005 Jun 7.PMID: 15942053 [PubMed - indexed for MEDLINE]Related articlesFree article

ClC-5: role in endocytosis in the proximal tubule.

Wang Y, Cai H, Cebotaru L, Hryciw DH, Weinman EJ, Donowitz M, Guggino SE, Guggino WB.

Am J Physiol Renal Physiol. 2005 Oct;289(4):F850-62. Epub 2005 Jun 7.PMID: 15942052 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.

Weinman EJ, Cunningham R, Wade JB, Shenolikar S.

J Physiol. 2005 Aug 15;567(Pt 1):27-32. Epub 2005 Jun 2. Review.PMID: 15932893 [PubMed - indexed for MEDLINE]Related articlesFree article

Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1.

Bomberger JM, Spielman WS, Hall CS, Weinman EJ, Parameswaran N.

J Biol Chem. 2005 Jun 24;280(25):23926-35. Epub 2005 Apr 1.PMID: 15805108 [PubMed - indexed for MEDLINE]Related articlesFree article

NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.

Weinman EJ, Cunningham R, Shenolikar S.

Pflugers Arch. 2005 Jun;450(3):137-44. Epub 2005 Mar 2. Review.PMID: 15742180 [PubMed - indexed for MEDLINE]Related articles

Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta.

Lee-Kwon W, Wade JB, Zhang Z, Pallone TL, Weinman EJ.

Am J Physiol Cell Physiol. 2005 Apr;288(4):C942-9. Epub 2004 Dec 8.PMID: 15590898 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of ion transport by the NHERF family of PDZ proteins.

Shenolikar S, Voltz JW, Cunningham R, Weinman EJ.

Physiology (Bethesda). 2004 Dec;19:362-9. Review.PMID: 15546854 [PubMed - indexed for MEDLINE]Related articlesFree article

Pyelonephritis and acute renal failure.

Nahar A, Akom M, Hanes D, Briglia A, Drachenberg CB, Weinman EJ.

Am J Med Sci. 2004 Aug;328(2):121-3.PMID: 15311172 [PubMed - indexed for MEDLINE]Related articles

Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells.

Cunningham R, Steplock D, Wang F, Huang H, E X, Shenolikar S, Weinman EJ.

J Biol Chem. 2004 Sep 3;279(36):37815-21. Epub 2004 Jun 24.PMID: 15218020 [PubMed - indexed for MEDLINE]Related articlesFree article

kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.

Huang P, Steplock D, Weinman EJ, Hall RA, Ding Z, Li J, Wang Y, Liu-Chen LY.

J Biol Chem. 2004 Jun 11;279(24):25002-9. Epub 2004 Apr 7.PMID: 15070904 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B.

Boehmer C, Embark HM, Bauer A, Palmada M, Yun CH, Weinman EJ, Endou H, Cohen P, Lahme S, Bichler KH, Lang F.

Biochem Biophys Res Commun. 2004 Jan 23;313(4):998-1003.PMID: 14706641 [PubMed - indexed for MEDLINE]Related articles

A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange.

Weinman EJ, Wang Y, Wang F, Greer C, Steplock D, Shenolikar S.

Biochemistry. 2003 Nov 4;42(43):12662-8.PMID: 14580213 [PubMed - indexed for MEDLINE]Related articles

NHERF-1 is required for renal adaptation to a low-phosphate diet.

Weinman EJ, Boddeti A, Cunningham R, Akom M, Wang F, Wang Y, Liu J, Steplock D, Shenolikar S, Wade JB.

Am J Physiol Renal Physiol. 2003 Dec;285(6):F1225-32. Epub 2003 Sep 2.PMID: 12952857 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

Sneddon WB, Syme CA, Bisello A, Magyar CE, Rochdi MD, Parent JL, Weinman EJ, Abou-Samra AB, Friedman PA.

J Biol Chem. 2003 Oct 31;278(44):43787-96. Epub 2003 Aug 14.PMID: 12920119 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.

Wade JB, Liu J, Coleman RA, Cunningham R, Steplock DA, Lee-Kwon W, Pallone TL, Shenolikar S, Weinman EJ.

Am J Physiol Cell Physiol. 2003 Dec;285(6):C1494-503. Epub 2003 Aug 13.PMID: 12917102 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of NHERF-1, NHERF-2, PDGFR-alpha, and PDGFR-beta in normal human kidneys and in renal transplant rejection.

Weinman EJ, Lakkis J, Akom M, Wali RK, Drachenberg CB, Coleman RA, Wade JB.

Pathobiology. 2002-2003;70(6):314-23.PMID: 12865627 [PubMed - indexed for MEDLINE]Related articles

Role of NHERF-1 in regulation of the activity of Na-K ATPase and sodium-phosphate co-transport in epithelial cells.

Lederer ED, Khundmiri SJ, Weinman EJ.

J Am Soc Nephrol. 2003 Jul;14(7):1711-9.PMID: 12819230 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+-dependent phosphate transporters in the murine osteoclast: cellular distribution and protein interactions.

Khadeer MA, Tang Z, Tenenhouse HS, Eiden MV, Murer H, Hernando N, Weinman EJ, Chellaiah MA, Gupta A.

Am J Physiol Cell Physiol. 2003 Jun;284(6):C1633-44. Epub 2003 Feb 26.PMID: 12606316 [PubMed - indexed for MEDLINE]Related articlesFree article

NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes.

Weinman EJ, Steplock D, Shenolikar S.

FEBS Lett. 2003 Feb 11;536(1-3):141-4.PMID: 12586353 [PubMed - indexed for MEDLINE]Related articles

The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1.

Yun CC, Palmada M, Embark HM, Fedorenko O, Feng Y, Henke G, Setiawan I, Boehmer C, Weinman EJ, Sandrasagra S, Korbmacher C, Cohen P, Pearce D, Lang F.

J Am Soc Nephrol. 2002 Dec;13(12):2823-30.PMID: 12444200 [PubMed - indexed for MEDLINE]Related articlesFree article

PDZ-domain interactions and apical expression of type IIa Na/P(i) cotransporters.

Hernando N, Déliot N, Gisler SM, Lederer E, Weinman EJ, Biber J, Murer H.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11957-62. Epub 2002 Aug 21.PMID: 12192091 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting.

Shenolikar S, Voltz JW, Minkoff CM, Wade JB, Weinman EJ.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11470-5. Epub 2002 Aug 8.PMID: 12169661 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression, localization, and regulation of aquaporin-1 to -3 in rat urothelia.

Spector DA, Wade JB, Dillow R, Steplock DA, Weinman EJ.

Am J Physiol Renal Physiol. 2002 Jun;282(6):F1034-42.PMID: 11997319 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3.

Li X, Galli T, Leu S, Wade JB, Weinman EJ, Leung G, Cheong A, Louvard D, Donowitz M.

J Physiol. 2001 Dec 1;537(Pt 2):537-52.PMID: 11731584 [PubMed - indexed for MEDLINE]Related articlesFree article

Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation.

Voltz JW, Weinman EJ, Shenolikar S.

Oncogene. 2001 Oct 1;20(44):6309-14. Review.PMID: 11607833 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role for NHERF in cAMP-mediated inhibition of the Na+-HCO3- co-transporter in BSC-1 cells.

Weinman EJ, Evangelista CM, Steplock D, Liu MZ, Shenolikar S, Bernardo A.

J Biol Chem. 2001 Nov 9;276(45):42339-46. Epub 2001 Sep 4.PMID: 11535598 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute regulation of NHE3 by protein kinase A requires a multiprotein signal complex.

Weinman EJ, Steplock D, Shenolikar S.

Kidney Int. 2001 Aug;60(2):450-4. Review.PMID: 11473625 [PubMed - indexed for MEDLINE]Related articlesFree article