PubMed

Brain MRI Lesion Load at 1.5T and 3T versus Clinical Status in Multiple Sclerosis.

Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R.

J Neuroimaging. 2009 Nov 3. [Epub ahead of print]PMID: 19888926 [PubMed - as supplied by publisher]Related articles

Novel CD8(+) Treg suppress EAE by TGF-beta- and IFN-gamma-dependent mechanisms.

Chen ML, Yan BS, Kozoriz D, Weiner HL.

Eur J Immunol. 2009 Sep 18. [Epub ahead of print]PMID: 19768696 [PubMed - as supplied by publisher]Related articles

Refractory epilepsy in tuberous sclerosis: Vagus nerve stimulation with or without subsequent resective surgery.

Elliott RE, Carlson C, Kalhorn SP, Moshel YA, Weiner HL, Devinsky O, Doyle WK.

Epilepsy Behav. 2009 Nov;16(3):454-60. Epub 2009 Sep 19.PMID: 19767244 [PubMed - in process]Related articles

Oral Administration of OKT3 Monoclonal Antibody to Human Subjects Induces a Dose-Dependent Immunologic Effect in T Cells and Dendritic Cells.

Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL.

J Clin Immunol. 2009 Sep 16. [Epub ahead of print]PMID: 19756989 [PubMed - as supplied by publisher]Related articles

Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data.

Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R, Guttmann CR.

AJNR Am J Neuroradiol. 2009 Oct;30(9):1731-9. Epub 2009 Aug 20.PMID: 19696139 [PubMed - in process]Related articles

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

Farez MF, Quintana FJ, Gandhi R, Izquierdo G, Lucas M, Weiner HL.

Nat Immunol. 2009 Sep;10(9):958-64. Epub 2009 Aug 16.PMID: 19684606 [PubMed - indexed for MEDLINE]Related articles

HLA-DR alleles in amyloid beta-peptide autoimmunity: a highly immunogenic role for the DRB1*1501 allele.

Zota V, Nemirovsky A, Baron R, Fisher Y, Selkoe DJ, Altmann DM, Weiner HL, Monsonego A.

J Immunol. 2009 Sep 1;183(5):3522-30. Epub 2009 Aug 12.PMID: 19675171 [PubMed - indexed for MEDLINE]Related articles

IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells.

Murugaiyan G, Mittal A, Lopez-Diego R, Maier LM, Anderson DE, Weiner HL.

J Immunol. 2009 Aug 15;183(4):2435-43. Epub 2009 Jul 22.PMID: 19625647 [PubMed - indexed for MEDLINE]Related articles

Extraventricular subependymal giant cell tumor in a child with tuberous sclerosis complex.

Bollo RJ, Berliner JL, Fischer I, Miles DK, Thiele EA, Zagzag D, Weiner HL.

J Neurosurg Pediatr. 2009 Jul;4(1):85-90.PMID: 19569916 [PubMed - indexed for MEDLINE]Related articles

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR.

Nat Genet. 2009 Jul;41(7):776-82. Epub 2009 Jun 14.PMID: 19525953 [PubMed - indexed for MEDLINE]Related articlesFree article

Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.

Frenkel D, Pachori AS, Zhang L, Dembinsky-Vaknin A, Farfara D, Petrovic-Stojkovic S, Dzau VJ, Weiner HL.

Int Immunol. 2009 Jul;21(7):817-29. Epub 2009 Jun 10.PMID: 19515797 [PubMed - indexed for MEDLINE]Related articles

Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.

Kivisäkk P, Healy BC, Viglietta V, Quintana FJ, Hootstein MA, Weiner HL, Khoury SJ.

Neurology. 2009 Jun 2;72(22):1922-30.PMID: 19487650 [PubMed - indexed for MEDLINE]Related articles

Extraoperative functional mapping and staged resection of supratentorial tumors near eloquent cortex in children.

Bollo RJ, Carlson C, Schevon C, Wisoff JH, Devinsky O, Weiner HL.

Pediatr Neurosurg. 2009;45(3):175-80. Epub 2009 May 14.PMID: 19440004 [PubMed - indexed for MEDLINE]Related articles

Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells.

Wu HY, Center EM, Tsokos GC, Weiner HL.

Lupus. 2009 Jun;18(7):586-96.PMID: 19433458 [PubMed - indexed for MEDLINE]Related articlesFree article

Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study.

Gauthier SA, Glanz BI, Mandel M, Tsagkaropoulos A, Neema M, Stankiewicz J, Arora A, Duan Y, Liptak Z, Egorova S, Buckle GJ, Bakshi R, Guttmann CR, Khoury SJ, Weiner HL.

J Neurol Sci. 2009 Sep 15;284(1-2):116-9. Epub 2009 May 9.PMID: 19428028 [PubMed - in process]Related articles

The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?

Weiner HL.

Ann Neurol. 2009 Mar;65(3):239-48. Review.PMID: 19334069 [PubMed - indexed for MEDLINE]Related articles

Environmental control of Th17 differentiation.

Quintana FJ, Weiner HL.

Eur J Immunol. 2009 Mar;39(3):655-7.PMID: 19283716 [PubMed - indexed for MEDLINE]Related articles

3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis.

Neema M, Goldberg-Zimring D, Guss ZD, Healy BC, Guttmann CR, Houtchens MK, Weiner HL, Horsfield MA, Hackney DB, Alsop DC, Bakshi R.

Neuroimage. 2009 Jul 1;46(3):633-41. Epub 2009 Mar 10.PMID: 19281850 [PubMed - indexed for MEDLINE]Related articles

The role of the CD58 locus in multiple sclerosis.

De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5264-9. Epub 2009 Feb 23.PMID: 19237575 [PubMed - indexed for MEDLINE]Related articlesFree article

Rate of brain atrophy in benign vs early multiple sclerosis.

Gauthier SA, Berger AM, Liptak Z, Duan Y, Egorova S, Buckle GJ, Glanz BI, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR.

Arch Neurol. 2009 Feb;66(2):234-7.PMID: 19204160 [PubMed - indexed for MEDLINE]Related articles

Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis.

Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R.

J Neuroimaging. 2009 Jan;19(1):3-8.PMID: 19192042 [PubMed - indexed for MEDLINE]Related articlesFree article

Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis.

Yang K, Vega JL, Hadzipasic M, Schatzmann Peron JP, Zhu B, Carrier Y, Masli S, Rizzo LV, Weiner HL.

J Autoimmun. 2009 Mar;32(2):94-103. Epub 2009 Feb 1.PMID: 19181483 [PubMed - indexed for MEDLINE]Related articles

Daclizumab in treatment of multiple sclerosis patients.

Ali EN, Healy BC, Stazzone LA, Brown BA, Weiner HL, Khoury SJ.

Mult Scler. 2009 Feb;15(2):272-4. Epub 2009 Jan 9.PMID: 19136546 [PubMed - indexed for MEDLINE]Related articles

Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression.

Mandel M, Gauthier SA, Guttmann CR, Weiner HL, Betensky RA.

J Am Stat Assoc. 2007 Dec;102(480):1254-1266.PMID: 19081806 [PubMed]Related articlesFree article

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis.

Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18889-94. Epub 2008 Nov 21.PMID: 19028871 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis.

Murugaiyan G, Mittal A, Weiner HL.

J Immunol. 2008 Dec 1;181(11):7480-8.PMID: 19017937 [PubMed - indexed for MEDLINE]Related articles

Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale.

Bakshi R, Neema M, Healy BC, Liptak Z, Betensky RA, Buckle GJ, Gauthier SA, Stankiewicz J, Meier D, Egorova S, Arora A, Guss ZD, Glanz B, Khoury SJ, Guttmann CR, Weiner HL.

Arch Neurol. 2008 Nov;65(11):1449-53.PMID: 19001162 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel therapeutic strategies for multiple sclerosis--a multifaceted adversary.

Lopez-Diego RS, Weiner HL.

Nat Rev Drug Discov. 2008 Nov;7(11):909-25. Review.PMID: 18974749 [PubMed - indexed for MEDLINE]Related articles

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.

Wu HY, Quintana FJ, Weiner HL.

J Immunol. 2008 Nov 1;181(9):6038-50.PMID: 18941193 [PubMed - indexed for MEDLINE]Related articlesFree article

New immunosuppressive approaches: oral administration of CD3-specific antibody to treat autoimmunity.

Ochi H, Abraham M, Ishikawa H, Frenkel D, Yang K, Basso A, Wu H, Chen ML, Gandhi R, Miller A, Maron R, Weiner HL.

J Neurol Sci. 2008 Nov 15;274(1-2):9-12. Epub 2008 Sep 18. Review.PMID: 18804221 [PubMed - indexed for MEDLINE]Related articles

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CR, Rusche JR, Khoury SJ.

Neurology. 2008 Sep 16;71(12):917-24.PMID: 18794494 [PubMed - indexed for MEDLINE]Related articles

Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratemporal epilepsy.

Bauman JA, Feoli E, Romanelli P, Doyle WK, Devinsky O, Weiner HL.

Neurosurgery. 2008 Feb;62 Suppl 2:489-505.PMID: 18596454 [PubMed]Related articles

Epilepsy surgery and tuberous sclerosis complex: special considerations.

Bollo RJ, Kalhorn SP, Carlson C, Haegeli V, Devinsky O, Weiner HL.

Neurosurg Focus. 2008 Sep;25(3):E13. Review.PMID: 18759614 [PubMed - indexed for MEDLINE]Related articles

Epilepsy surgery in tuberous sclerosis complex: early predictive elements and outcome.

Teutonico F, Mai R, Devinsky O, Lo Russo G, Weiner HL, Borrelli P, Balottin U, Veggiotti P.

Childs Nerv Syst. 2008 Dec;24(12):1437-45. Epub 2008 Aug 14.PMID: 18704447 [PubMed - indexed for MEDLINE]Related articles

Oral laquinimod for treatment of relapsing-remitting multiple sclerosis.

Weiner HL.

Lancet Neurol. 2008 Aug;7(8):672-3. No abstract available. PMID: 18635014 [PubMed - indexed for MEDLINE]Related articles

Glioma-like proliferation within tissues excised as tubers in patients with tuberous sclerosis complex.

Fischer I, Cunliffe C, Bollo RJ, Weiner HL, Devinsky O, Ruiz-Tachiquin ME, Venuto T, Pearlman A, Chiriboga L, Schneider RJ, Ostrer H, Miller DC.

Acta Neuropathol. 2008 Jul;116(1):67-77. Epub 2008 Jun 26.PMID: 18581125 [PubMed - indexed for MEDLINE]Related articles

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells.

De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL.

Brain. 2008 Jul;131(Pt 7):1701-11. Epub 2008 Jun 21.PMID: 18567923 [PubMed - indexed for MEDLINE]Related articlesFree article

Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis.

Liptak Z, Berger AM, Sampat MP, Charil A, Felsovalyi O, Healy BC, Hildenbrand P, Khoury SJ, Weiner HL, Bakshi R, Guttmann CR.

AJNR Am J Neuroradiol. 2008 Sep;29(8):1465-70. Epub 2008 Jun 12.PMID: 18556361 [PubMed - indexed for MEDLINE]Related articlesFree article

Systems biology approaches for the study of multiple sclerosis.

Quintana FJ, Farez MF, Weiner HL.

J Cell Mol Med. 2008 Aug;12(4):1087-93. Epub 2008 May 26. Review.PMID: 18505469 [PubMed - indexed for MEDLINE]Related articles

Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis.

Chen ML, Yan BS, Bando Y, Kuchroo VK, Weiner HL.

J Immunol. 2008 Jun 1;180(11):7327-37.PMID: 18490732 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis.

Vaknin-Dembinsky A, Murugaiyan G, Hafler DA, Astier AL, Weiner HL.

J Neuroimmunol. 2008 Mar;195(1-2):140-5. Epub 2008 Apr 10.PMID: 18403025 [PubMed - indexed for MEDLINE]Related articlesFree article

A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis.

Weiner HL.

J Neurol. 2008 Mar;255 Suppl 1:3-11. Review.PMID: 18317671 [PubMed - indexed for MEDLINE]Related articles

Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS.

Vaknin-Dembinsky A, Brass SD, Gandhi R, Weiner HL.

J Neuroimmunol. 2008 Mar;195(1-2):135-9. Epub 2008 Apr 1. Erratum in: J Neuroimmunol. 2009 Feb 15;207(1-2):122. Brass, Steven [corrected to Brass, Steven D]. PMID: 18378324 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E, Caccamo M, Oukka M, Weiner HL.

Nature. 2008 May 1;453(7191):65-71. Epub 2008 Mar 23.PMID: 18362915 [PubMed - indexed for MEDLINE]Related articles

A nasal proteosome adjuvant activates microglia and prevents amyloid deposition.

Frenkel D, Puckett L, Petrovic S, Xia W, Chen G, Vega J, Dembinsky-Vaknin A, Shen J, Plante M, Burt DS, Weiner HL.

Ann Neurol. 2008 May;63(5):591-601.PMID: 18360829 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.

Basso AS, Frenkel D, Quintana FJ, Costa-Pinto FA, Petrovic-Stojkovic S, Puckett L, Monsonego A, Bar-Shir A, Engel Y, Gozin M, Weiner HL.

J Clin Invest. 2008 Apr;118(4):1532-43.PMID: 18340379 [PubMed - indexed for MEDLINE]Related articlesFree article

Tuberous sclerosis: a primary pathology of astrocytes?

Sosunov AA, Wu X, Weiner HL, Mikell CB, Goodman RR, Crino PD, McKhann GM 2nd.

Epilepsia. 2008;49 Suppl 2:53-62.PMID: 18226172 [PubMed - indexed for MEDLINE]Related articles

Regulating rejection with cell therapy.

Sayegh MH, Weiner HL.

Nat Biotechnol. 2008 Feb;26(2):191-2. No abstract available. PMID: 18259174 [PubMed - indexed for MEDLINE]Related articles

In vitro induction of regulatory T cells by anti-CD3 antibody in humans.

Abraham M, Karni A, Dembinsky A, Miller A, Gandhi R, Anderson D, Weiner HL.

J Autoimmun. 2008 Feb-Mar;30(1-2):21-8.PMID: 18191540 [PubMed - indexed for MEDLINE]Related articlesFree article

MR imaging intensity modeling of damage and repair in multiple sclerosis: relationship of short-term lesion recovery to progression and disability.

Meier DS, Weiner HL, Guttmann CR.

AJNR Am J Neuroradiol. 2007 Nov-Dec;28(10):1956-63.PMID: 17998417 [PubMed - indexed for MEDLINE]Related articlesFree article