PubMed

Dietary n-3-polyunsaturated fatty acids and energy balance in overweight or moderately obese men and women: a randomized controlled trial.

Kratz M, Callahan HS, Yang PY, Matthys CC, Weigle DS.

Nutr Metab (Lond). 2009 May 29;6:24.PMID: 19480700 [PubMed - in process]Related articlesFree article

Hypercaloric diets differing in fat composition have similar effects on serum leptin and weight gain in female subjects with anorexia nervosa.

Mauler B, Dubben S, Pawelzik M, Pawelzik D, Weigle DS, Kratz M.

Nutr Res. 2009 Jan;29(1):1-7.PMID: 19185771 [PubMed - indexed for MEDLINE]Related articles

Leptin levels recover normally in healthy older adults after acute diet-induced weight loss.

Yukawa M, Phelan EA, Callahan HS, Spiekerman CF, Abrass IB, Weigle DS.

J Nutr Health Aging. 2008 Nov;12(9):652-6.PMID: 18953464 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy balance in congenital generalized lipodystrophy type I.

Taleban S, Carew HT, Dichek HL, Deeb SS, Hollenback D, Weigle DS, Cummings DE, Brunzell JD.

Metabolism. 2008 Aug;57(8):1155-61.PMID: 18640396 [PubMed - indexed for MEDLINE]Related articles

Serum leptin concentrations and markers of immune function in overweight or obese postmenopausal women.

Meyers JA, Liu AY, McTiernan A, Wener MH, Wood B, Weigle DS, Sorensen B, Chen-Levy Z, Yasui Y, Boynton A, Potter JD, Ulrich CM.

J Endocrinol. 2008 Oct;199(1):51-60. Epub 2008 Jul 9.PMID: 18614715 [PubMed - indexed for MEDLINE]Related articlesFree article

The obesity epidemic: pharmacological challenges.

Bloom SR, Kuhajda FP, Laher I, Pi-Sunyer X, Ronnett GV, Tan TM, Weigle DS.

Mol Interv. 2008 Apr;8(2):82-98. Review.PMID: 18403653 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral ghrelin treatment stabilizes body weights of senescent male Brown Norway rats at baseline and after surgery.

Yukawa M, Weigle DS, Davis CD, Marck BT, Wolden-Hanson T.

Am J Physiol Regul Integr Comp Physiol. 2008 May;294(5):R1453-60. Epub 2008 Mar 12.PMID: 18337314 [PubMed - indexed for MEDLINE]Related articles

Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecular-weight adiponectin concentrations in overweight to moderately obese men and women.

Kratz M, Swarbrick MM, Callahan HS, Matthys CC, Havel PJ, Weigle DS.

Am J Clin Nutr. 2008 Feb;87(2):347-53.PMID: 18258624 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy.

Kratz M, Purnell JQ, Breen PA, Thomas KK, Utzschneider KM, Carr DB, Kahn SE, Hughes JP, Rutledge EA, Van Yserloo B, Yukawa M, Weigle DS.

J Clin Endocrinol Metab. 2008 Mar;93(3):959-66. Epub 2007 Dec 18.PMID: 18089690 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptation to altitude as a vehicle for experiential learning of physiology by university undergraduates.

Weigle DS, Buben A, Burke CC, Carroll ND, Cook BM, Davis BS, Dubowitz G, Fisher RE, Freeman TC, Gibbons SM, Hansen HA, Heys KA, Hopkins B, Jordan BL, McElwain KL, Powell FL, Reinhart KE, Robbins CD, Summers CC, Walker JD, Weber SS, Weinheimer CJ.

Adv Physiol Educ. 2007 Sep;31(3):270-8.PMID: 17848594 [PubMed - indexed for MEDLINE]Related articlesFree article

Modified macronutrient diets and weight loss--are food choice and variety more important than caloric restriction?

Weigle DS.

Nat Clin Pract Endocrinol Metab. 2007 Nov;3(11):728-9. Epub 2007 Sep 4. Review. No abstract available. PMID: 17768405 [PubMed - indexed for MEDLINE]Related articles

Changes in plasma amino Acid levels do not predict satiety and weight loss on diets with modified macronutrient composition.

Koren MS, Purnell JQ, Breen PA, Matthys CC, Callahan HS, Meeuws KE, Burden VR, Weigle DS.

Ann Nutr Metab. 2007;51(2):182-7. Epub 2007 May 30.PMID: 17541265 [PubMed - indexed for MEDLINE]Related articles

Sleep, ghrelin, leptin and changes in body weight during a 1-year moderate-intensity physical activity intervention.

Littman AJ, Vitiello MV, Foster-Schubert K, Ulrich CM, Tworoger SS, Potter JD, Weigle DS, McTiernan A.

Int J Obes (Lond). 2007 Mar;31(3):466-75. Epub 2006 Aug 15.PMID: 16909130 [PubMed - indexed for MEDLINE]Related articles

Changes in 24-h area-under-the-curve ghrelin values following diet-induced weight loss are associated with loss of fat-free mass, but not with changes in fat mass, insulin levels or insulin sensitivity.

Purnell JQ, Cummings D, Weigle DS.

Int J Obes (Lond). 2007 Feb;31(2):385-9. Epub 2006 Jul 4.PMID: 16819531 [PubMed - indexed for MEDLINE]Related articles

Effect of aging on the response of ghrelin to acute weight loss.

Yukawa M, Cummings DE, Matthys CC, Callahan HS, Frayo RS, Spiekerman CF, Weigle DS.

J Am Geriatr Soc. 2006 Apr;54(4):648-53.PMID: 16686877 [PubMed - indexed for MEDLINE]Related articles

Plasma C-reactive protein concentration is not affected by isocaloric dietary fat reduction.

Koren MS, Purnell JQ, Breen PA, Matthys CC, Callahan HS, Weigle DS.

Nutrition. 2006 Apr;22(4):444-8. Epub 2006 Feb 3.PMID: 16458481 [PubMed - indexed for MEDLINE]Related articles

Evaluation of leptin levels in subjects at risk for type 1 diabetes.

Gilliam LK, Jensen RA, Yang P, Weigle DS, Greenbaum CJ, Pihoker C.

J Autoimmun. 2006 Mar;26(2):133-7. Epub 2005 Dec 27.PMID: 16380228 [PubMed - indexed for MEDLINE]Related articles

A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations.

Weigle DS, Breen PA, Matthys CC, Callahan HS, Meeuws KE, Burden VR, Purnell JQ.

Am J Clin Nutr. 2005 Jul;82(1):41-8.PMID: 16002798 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial.

Frank LL, Sorensen BE, Yasui Y, Tworoger SS, Schwartz RS, Ulrich CM, Irwin ML, Rudolph RE, Rajan KB, Stanczyk F, Bowen D, Weigle DS, Potter JD, McTiernan A.

Obes Res. 2005 Mar;13(3):615-25.PMID: 15833948 [PubMed - indexed for MEDLINE]Related articles

Insulin, C-peptide, and leptin concentrations predict increased visceral adiposity at 5- and 10-year follow-ups in nondiabetic Japanese Americans.

Tong J, Fujimoto WY, Kahn SE, Weigle DS, McNeely MJ, Leonetti DL, Shofer JB, Boyko EJ.

Diabetes. 2005 Apr;54(4):985-90.PMID: 15793236 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes.

Frankenfeld CL, McTiernan A, Tworoger SS, Atkinson C, Thomas WK, Stanczyk FZ, Marcovina SM, Weigle DS, Weiss NS, Holt VL, Schwartz SM, Lampe JW.

J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):399-408.PMID: 15145450 [PubMed - indexed for MEDLINE]Related articles

Postprandial suppression of plasma ghrelin level is proportional to ingested caloric load but does not predict intermeal interval in humans.

Callahan HS, Cummings DE, Pepe MS, Breen PA, Matthys CC, Weigle DS.

J Clin Endocrinol Metab. 2004 Mar;89(3):1319-24.PMID: 15001628 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin levels correlate with insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not with gender, menopausal status, or cortisol levels in humans.

Purnell JQ, Weigle DS, Breen P, Cummings DE.

J Clin Endocrinol Metab. 2003 Dec;88(12):5747-52.PMID: 14671163 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome.

Haqq AM, Stadler DD, Rosenfeld RG, Pratt KL, Weigle DS, Frayo RS, LaFranchi SH, Cummings DE, Purnell JQ.

J Clin Endocrinol Metab. 2003 Aug;88(8):3573-6.PMID: 12915638 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacological therapy of obesity: past, present, and future.

Weigle DS.

J Clin Endocrinol Metab. 2003 Jun;88(6):2462-9. Review. No abstract available. PMID: 12788841 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet.

Weigle DS, Cummings DE, Newby PD, Breen PA, Frayo RS, Matthys CC, Callahan HS, Purnell JQ.

J Clin Endocrinol Metab. 2003 Apr;88(4):1577-86.PMID: 12679442 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of hypersensitivity to glucocorticoids in antiretroviral-associated lipodystrophy.

Martin IP, Breen PA, Weigle DS.

Obes Res. 2003 Jan;11(1):21-4.PMID: 12529481 [PubMed - indexed for MEDLINE]Related articles

Leptin levels are appropriate for body mass index in older men who experience involuntary weight loss.

Yukawa M, McCormick WC, Rajan S, Matsumoto AM, Wallace JI, Pearlman RA, Weigle DS.

J Am Geriatr Soc. 2002 Sep;50(9):1566-71.PMID: 12383156 [PubMed - indexed for MEDLINE]Related articles

Elevated plasma ghrelin levels in Prader Willi syndrome.

Cummings DE, Clement K, Purnell JQ, Vaisse C, Foster KE, Frayo RS, Schwartz MW, Basdevant A, Weigle DS.

Nat Med. 2002 Jul;8(7):643-4. No abstract available. PMID: 12091883 [PubMed - indexed for MEDLINE]Related articles

Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ.

N Engl J Med. 2002 May 23;346(21):1623-30.PMID: 12023994 [PubMed - indexed for MEDLINE]Related articlesFree article

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.

Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS.

Diabetes. 2001 Aug;50(8):1714-9.PMID: 11473029 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective dietary induction of uncoupling protein 3 in skeletal muscle of obesity-prone rats.

Weigle DS, Levin BE.

Obes Res. 2000 Aug;8(5):385-91.PMID: 10968730 [PubMed - indexed for MEDLINE]Related articles

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats.

Havel PJ, Hahn TM, Sindelar DK, Baskin DG, Dallman MF, Weigle DS, Schwartz MW.

Diabetes. 2000 Feb;49(2):244-52.PMID: 10868941 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between baseline plasma leptin levels and subsequent development of diabetes in Japanese Americans.

McNeely MJ, Boyko EJ, Weigle DS, Shofer JB, Chessler SD, Leonnetti DL, Fujimoto WY.

Diabetes Care. 1999 Jan;22(1):65-70.PMID: 10333905 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of energy intake on the regulation of plasma leptin concentrations.

Duell PB, Weigle DS, Connor WE.

Am J Clin Nutr. 1998 Dec;68(6):1304. No abstract available. PMID: 9846863 [PubMed - indexed for MEDLINE]Related articles

Leptin does not fully account for the satiety activity of adipose tissue-conditioned medium.

Weigle DS, Hutson AM, Kramer JM, Fallon MG, Lehner JM, Lok S, Kuijper JL.

Am J Physiol. 1998 Oct;275(4 Pt 2):R976-85.PMID: 9756525 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting.

Baskin DG, Seeley RJ, Kuijper JL, Lok S, Weigle DS, Erickson JC, Palmiter RD, Schwartz MW.

Diabetes. 1998 Apr;47(4):538-43.PMID: 9568684 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting.

Weigle DS, Selfridge LE, Schwartz MW, Seeley RJ, Cummings DE, Havel PJ, Kuijper JL, BeltrandelRio H.

Diabetes. 1998 Feb;47(2):298-302.PMID: 9519732 [PubMed - indexed for MEDLINE]Related articles

Increased plasma leptin levels are associated with fat accumulation in Japanese Americans.

Chessler SD, Fujimoto WY, Shofer JB, Boyko EJ, Weigle DS.

Diabetes. 1998 Feb;47(2):239-43.PMID: 9519719 [PubMed - indexed for MEDLINE]Related articles

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

Schwartz MW, Seeley RJ, Woods SC, Weigle DS, Campfield LA, Burn P, Baskin DG.

Diabetes. 1997 Dec;46(12):2119-23.PMID: 9392508 [PubMed - indexed for MEDLINE]Related articles

Recombinant leptin exchanges between parabiosed mice but does not reach equilibrium.

Harris RB, Zhou J, Weigle DS, Kuijper JL.

Am J Physiol. 1997 Jun;272(6 Pt 2):R1800-8.PMID: 9227593 [PubMed - indexed for MEDLINE]Related articles

Effect of regional fat distribution and Prader-Willi syndrome on plasma leptin levels.

Weigle DS, Ganter SL, Kuijper JL, Leonetti DL, Boyko EJ, Fujimoto WY.

J Clin Endocrinol Metab. 1997 Feb;82(2):566-70.PMID: 9024255 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels.

Weigle DS, Duell PB, Connor WE, Steiner RA, Soules MR, Kuijper JL.

J Clin Endocrinol Metab. 1997 Feb;82(2):561-5.PMID: 9024254 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin is a metabolic gate for the onset of puberty in the female rat.

Cheung CC, Thornton JE, Kuijper JL, Weigle DS, Clifton DK, Steiner RA.

Endocrinology. 1997 Feb;138(2):855-8.PMID: 9003028 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake.

Matson CA, Wiater MF, Kuijper JL, Weigle DS.

Peptides. 1997;18(8):1275-8.PMID: 9396073 [PubMed - indexed for MEDLINE]Related articles

Leptin and other secretory products of adipocytes modulate multiple physiological functions.

Weigle DS.

Ann Endocrinol (Paris). 1997;58(2):132-6. Review.PMID: 9239232 [PubMed - indexed for MEDLINE]Related articles

Obesity genes and the regulation of body fat content.

Weigle DS, Kuijper JL.

Bioessays. 1996 Nov;18(11):867-74. Review.PMID: 8939064 [PubMed - indexed for MEDLINE]Related articles

Leptin is a metabolic signal to the reproductive system.

Barash IA, Cheung CC, Weigle DS, Ren H, Kabigting EB, Kuijper JL, Clifton DK, Steiner RA.

Endocrinology. 1996 Jul;137(7):3144-7.PMID: 8770941 [PubMed - indexed for MEDLINE]Related articles

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.

Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr, Woods SC, Seeley RJ, Weigle DS.

Diabetes. 1996 Apr;45(4):531-5.PMID: 8603777 [PubMed - indexed for MEDLINE]Related articles

Frequency of thyroid disease among Southeast Asian primary care patients.

Weigle DS, Hooton TM, Toivola B, Kith P, Buchwald D.

J Clin Pharm Ther. 1996 Feb;21(1):29-35.PMID: 8737181 [PubMed - indexed for MEDLINE]Related articles