PubMed

Application of a short intracellular pH method to flow cytometry for determining Saccharomyces cerevisiae vitality.

Weigert C, Steffler F, Kurz T, Shellhammer TH, Methner FJ.

Appl Environ Microbiol. 2009 Sep;75(17):5615-20. Epub 2009 Jul 6.PMID: 19581482 [PubMed - indexed for MEDLINE]Related articles

Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo.

Peter A, Weigert C, Staiger H, Machicao F, Schick F, Machann J, Stefan N, Thamer C, Häring HU, Schleicher E.

Diabetes. 2009 Aug;58(8):1757-65. Epub 2009 May 28.PMID: 19478146 [PubMed - indexed for MEDLINE]Related articlesFree article

Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain.

Hennige AM, Heni M, Machann J, Staiger H, Sartorius T, Hoene M, Lehmann R, Weigert C, Peter A, Bornemann A, Kroeber S, Pujol A, Franckhauser S, Bosch F, Schick F, Lammers R, Håring HU.

J Cell Mol Med. 2008 Dec 24. [Epub ahead of print]PMID: 19413892 [PubMed - as supplied by publisher]Related articles

Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise.

Hoene M, Lehmann R, Hennige AM, Pohl AK, Häring HU, Schleicher ED, Weigert C.

J Physiol. 2009 Jan 15;587(Pt 1):241-52. Epub 2008 Nov 10.PMID: 19001047 [PubMed - indexed for MEDLINE]Related articles

Interplay and effects of temporal changes in the phosphorylation state of serine-302, -307, and -318 of insulin receptor substrate-1 on insulin action in skeletal muscle cells.

Weigert C, Kron M, Kalbacher H, Pohl AK, Runge H, Häring HU, Schleicher E, Lehmann R.

Mol Endocrinol. 2008 Dec;22(12):2729-40. Epub 2008 Oct 16.PMID: 18927238 [PubMed - indexed for MEDLINE]Related articles

Development and precise characterization of phospho-site-specific antibody of Ser(357) of IRS-1: elimination of cross reactivity with adjacent Ser(358).

Waraich RS, Zaidi N, Moeschel K, Beck A, Weigert C, Voelter W, Kalbacher H, Lehmann R.

Biochem Biophys Res Commun. 2008 Nov 7;376(1):26-31. Epub 2008 Aug 24.PMID: 18725197 [PubMed - indexed for MEDLINE]Related articles

How insulin receptor substrate proteins regulate the metabolic capacity of the liver--implications for health and disease.

Fritsche L, Weigert C, Häring HU, Lehmann R.

Curr Med Chem. 2008;15(13):1316-29. Review.PMID: 18537611 [PubMed - indexed for MEDLINE]Related articles

Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity.

Peter A, Weigert C, Staiger H, Rittig K, Cegan A, Lutz P, Machicao F, Häring HU, Schleicher E.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E339-49. Epub 2008 Jun 3.PMID: 18523127 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells.

Waraich RS, Weigert C, Kalbacher H, Hennige AM, Lutz SZ, Häring HU, Schleicher ED, Voelter W, Lehmann R.

J Biol Chem. 2008 Apr 25;283(17):11226-33. Epub 2008 Feb 19.PMID: 18285345 [PubMed - indexed for MEDLINE]Related articlesFree article

The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals.

Rittig K, Peter A, Baltz KM, Tschritter O, Weigert C, Andreozzi F, Perticone F, Siegel-Axel DI, Stefan N, Fritsche A, Salih HR, Schleicher E, Machicao F, Sesti G, Häring HU, Balletshofer BM.

Atherosclerosis. 2008 Jun;198(2):338-46. Epub 2007 Dec 21.PMID: 18096169 [PubMed - indexed for MEDLINE]Related articles

Immunopathogenesis and role of T cells in psoriasis.

Ghoreschi K, Weigert C, Röcken M.

Clin Dermatol. 2007 Nov-Dec;25(6):574-80. Review.PMID: 18021895 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of serum- and glucocorticoid-inducible kinase 1 (SGK1) splice variants based on alternative initiation of transcription.

Simon P, Schneck M, Hochstetter T, Koutsouki E, Mittelbronn M, Merseburger A, Weigert C, Niess A, Lang F.

Cell Physiol Biochem. 2007;20(6):715-28.PMID: 17982254 [PubMed - indexed for MEDLINE]Related articles

The role of interleukin-6 in insulin resistance, body fat distribution and energy balance.

Hoene M, Weigert C.

Obes Rev. 2008 Jan;9(1):20-9. Epub 2007 Oct 23. Review.PMID: 17956545 [PubMed - indexed for MEDLINE]Related articles

Sense or antisense? False priming reverse transcription controls are required for determining sequence orientation by reverse transcription-PCR.

Beiter T, Reich E, Weigert C, Niess AM, Simon P.

Anal Biochem. 2007 Oct 15;369(2):258-61. Epub 2007 Jul 5. No abstract available. PMID: 17698025 [PubMed - indexed for MEDLINE]Related articles

Upregulation of IL-6 mRNA by IL-6 in skeletal muscle cells: role of IL-6 mRNA stabilization and Ca2+-dependent mechanisms.

Weigert C, Düfer M, Simon P, Debre E, Runge H, Brodbeck K, Häring HU, Schleicher ED.

Am J Physiol Cell Physiol. 2007 Sep;293(3):C1139-47. Epub 2007 Jul 5.PMID: 17615159 [PubMed - indexed for MEDLINE]Related articlesFree article

Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis.

Weigert C, Lehmann R, Schleicher ED.

J Appl Physiol. 2007 Feb;102(2):820-1; author reply 825. No abstract available. PMID: 17323462 [PubMed - indexed for MEDLINE]Related articles

Increased glucose uptake and metabolism in mesangial cells overexpressing glucose transporter 1 increases interleukin-6 and vascular endothelial growth factor production: role of AP-1 and HIF-1alpha.

Pfäfflin A, Brodbeck K, Heilig CW, Häring HU, Schleicher ED, Weigert C.

Cell Physiol Biochem. 2006;18(4-5):199-210.PMID: 17167225 [PubMed - indexed for MEDLINE]Related articles

Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-kappaB activation.

Staiger K, Staiger H, Weigert C, Haas C, Häring HU, Kellerer M.

Diabetes. 2006 Nov;55(11):3121-6.PMID: 17065351 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.

Hennige AM, Stefan N, Kapp K, Lehmann R, Weigert C, Beck A, Moeschel K, Mushack J, Schleicher E, Häring HU.

FASEB J. 2006 Jun;20(8):1206-8. Epub 2006 Apr 12.PMID: 16611834 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells.

Weigert C, Hennige AM, Lehmann R, Brodbeck K, Baumgartner F, Schaüble M, Häring HU, Schleicher ED.

J Biol Chem. 2006 Mar 17;281(11):7060-7. Epub 2006 Jan 17.PMID: 16418171 [PubMed - indexed for MEDLINE]Related articlesFree article

Fixed food eruption caused by asparagus.

Volz T, Berner D, Weigert C, Röcken M, Biedermann T.

J Allergy Clin Immunol. 2005 Dec;116(6):1390-2. Epub 2005 Nov 8. No abstract available. PMID: 16337479 [PubMed - indexed for MEDLINE]Related articles

A new variant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance.

Tschritter O, Machicao F, Stefan N, Schäfer S, Weigert C, Staiger H, Spieth C, Häring HU, Fritsche A.

J Clin Endocrinol Metab. 2006 Feb;91(2):654-8. Epub 2005 Nov 29.PMID: 16317062 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, Spieth C, Weigert C, Fritsche A, Stumvoll M, Häring HU.

Diabetologia. 2005 Nov;48(11):2282-91. Epub 2005 Oct 5.PMID: 16205883 [PubMed - indexed for MEDLINE]Related articles

The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal.

Weigert C, Hennige AM, Brischmann T, Beck A, Moeschel K, Schaüble M, Brodbeck K, Häring HU, Schleicher ED, Lehmann R.

J Biol Chem. 2005 Nov 11;280(45):37393-9. Epub 2005 Aug 29.PMID: 16129678 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-induced stimulation of JNK and the PI 3-kinase/mTOR pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes.

Müssig K, Fiedler H, Staiger H, Weigert C, Lehmann R, Schleicher ED, Häring HU.

Biochem Biophys Res Commun. 2005 Sep 30;335(3):819-25.PMID: 16099431 [PubMed - indexed for MEDLINE]Related articles

Role of glucoxidation and lipid oxidation in the development of atherosclerosis.

Schleicher E, Weigert C, Rohrbach H, Nerlich A, Bachmeier B, Friess U.

Ann N Y Acad Sci. 2005 Jun;1043:343-54.PMID: 16037256 [PubMed - indexed for MEDLINE]Related articles

Partial characterisation of the human GFAT promoter: effect of single nucleotide polymorphisms on promoter function.

Burt D, Brodbeck K, Häring HU, Schleicher ED, Weigert C.

Biochim Biophys Acta. 2005 Apr 15;1740(1):85-90. Epub 2005 Feb 12.PMID: 15878746 [PubMed - indexed for MEDLINE]Related articles

Co-transfection of messenger RNA and siRNA as a method to study the efficiency of siRNA.

Mutzke T, Schubkegel G, Teufel R, Ketterer T, Probst J, Scheel B, Carralot JP, Pascolo S, Ghoreschi K, Weigert C.

Nucleosides Nucleotides Nucleic Acids. 2005;24(2):147-52.PMID: 15822620 [PubMed - indexed for MEDLINE]Related articles

Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines.

Bachmeier BE, Albini A, Vené R, Benelli R, Noonan D, Weigert C, Weiler C, Lichtinghagen R, Jochum M, Nerlich AG.

Exp Cell Res. 2005 Apr 15;305(1):83-98.PMID: 15777790 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt.

Weigert C, Hennige AM, Brodbeck K, Häring HU, Schleicher ED.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E251-7. Epub 2005 Mar 8.PMID: 15755769 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin glulisine: insulin receptor signaling characteristics in vivo.

Hennige AM, Lehmann R, Weigert C, Moeschel K, Schäuble M, Metzinger E, Lammers R, Häring HU.

Diabetes. 2005 Feb;54(2):361-6.PMID: 15677493 [PubMed - indexed for MEDLINE]Related articlesFree article

The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects.

Weigert C, Thamer C, Brodbeck K, Guirguis A, Machicao F, Machann J, Schick F, Stumvoll M, Fritsche A, Häring HU, Schleicher ED.

J Clin Endocrinol Metab. 2005 Mar;90(3):1639-43. Epub 2004 Dec 21.PMID: 15613432 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1.

Moeschel K, Beck A, Weigert C, Lammers R, Kalbacher H, Voelter W, Schleicher ED, Häring HU, Lehmann R.

J Biol Chem. 2004 Jun 11;279(24):25157-63. Epub 2004 Apr 5.PMID: 15069075 [PubMed - indexed for MEDLINE]Related articlesFree article

Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB.

Weigert C, Brodbeck K, Staiger H, Kausch C, Machicao F, Häring HU, Schleicher ED.

J Biol Chem. 2004 Jun 4;279(23):23942-52. Epub 2004 Mar 17.PMID: 15028733 [PubMed - indexed for MEDLINE]Related articlesFree article

Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway.

Weigert C, Brodbeck K, Sawadogo M, Häring HU, Schleicher ED.

J Biol Chem. 2004 Apr 16;279(16):15908-15. Epub 2004 Feb 2.PMID: 14757763 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of cytosolic pH and lactic acid release in mesangial cells overexpressing GLUT1.

Lang KS, Mueller MM, Tanneur V, Wallisch S, Fedorenko O, Palmada M, Lang F, Bröer S, Heilig CW, Schleicher E, Weigert C.

Kidney Int. 2003 Oct;64(4):1338-47.PMID: 12969152 [PubMed - indexed for MEDLINE]Related articles

Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells.

Weigert C, Friess U, Brodbeck K, Häring HU, Schleicher ED.

Diabetologia. 2003 Jun;46(6):852-5. Epub 2003 Jun 11.PMID: 12802498 [PubMed - indexed for MEDLINE]Related articles

c-Fos-driven transcriptional activation of transforming growth factor beta-1: inhibition of high glucose-induced promoter activity by thiazolidinediones.

Weigert C, Brodbeck K, Bierhaus A, Häring HU, Schleicher ED.

Biochem Biophys Res Commun. 2003 May 2;304(2):301-7.PMID: 12711314 [PubMed - indexed for MEDLINE]Related articles

Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase.

Weigert C, Klopfer K, Kausch C, Brodbeck K, Stumvoll M, Häring HU, Schleicher ED.

Diabetes. 2003 Mar;52(3):650-6.PMID: 12606504 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a novel TGF-beta1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters.

Weigert C, Brodbeck K, Brosius FC 3rd, Huber M, Lehmann R, Friess U, Facchin S, Aulwurm S, Häring HU, Schleicher ED, Heilig CW.

Diabetes. 2003 Feb;52(2):527-35.PMID: 12540631 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of interferon-gamma expression by osmotic shrinkage of peripheral blood lymphocytes.

Lang KS, Weigert C, Braedel S, Fillon S, Palmada M, Schleicher E, Rammensee HG, Lang F.

Am J Physiol Cell Physiol. 2003 Jan;284(1):C200-8.PMID: 12475762 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II induces human TGF-beta 1 promoter activation: similarity to hyperglycaemia.

Weigert C, Brodbeck K, Klopfer K, Häring HU, Schleicher ED.

Diabetologia. 2002 Jun;45(6):890-8. Epub 2002 May 17.PMID: 12107734 [PubMed - indexed for MEDLINE]Related articles

Excessive transcription of the human serum and glucocorticoid dependent kinase hSGK1 in lung fibrosis.

Waerntges S, Klingel K, Weigert C, Fillon S, Buck M, Schleicher E, Rodemann HP, Knabbe C, Kandolf R, Lang F.

Cell Physiol Biochem. 2002;12(2-3):135-42.PMID: 12077559 [PubMed - indexed for MEDLINE]Related articles

PKC zeta enhances insulin-like growth factor 1-dependent mitogenic activity in the rat clonal beta cell line RIN 1046-38.

Hennige AM, Fritsche A, Strack V, Weigert C, Mischak H, Borboni P, Renn W, Häring HU, Kellerer M.

Biochem Biophys Res Commun. 2002 Jan 11;290(1):85-90.PMID: 11779137 [PubMed - indexed for MEDLINE]Related articles

Low-molecular-weight heparin prevents high glucose- and phorbol ester-induced TGF-beta 1 gene activation.

Weigert C, Brodbeck K, Häring HU, Gambaro G, Schleicher ED.

Kidney Int. 2001 Sep;60(3):935-43.PMID: 11532088 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of glutamine:fructose-6-phosphate-amidotransferase induces transforming growth factor-beta1 synthesis in NIH-3T3 fibroblasts.

Weigert C, Brodbeck K, Lehmann R, Häring HU, Schleicher ED.

FEBS Lett. 2001 Jan 12;488(1-2):95-9.PMID: 11163803 [PubMed - indexed for MEDLINE]Related articles

Inhibition of transforming growth factor-beta 1 gene overexpression as a strategy to prevent fibrosis.

Gambaro G, Weigert C, Ceol M, Schleicher ED.

Contrib Nephrol. 2001;(131):107-13. Review. No abstract available. PMID: 11125556 [PubMed - indexed for MEDLINE]Related articles

Glycosaminoglycan therapy prevents TGF-beta1 overexpression and pathologic changes in renal tissue of long-term diabetic rats.

Ceol M, Gambaro G, Sauer U, Baggio B, Anglani F, Forino M, Facchin S, Bordin L, Weigert C, Nerlich A, Schleicher ED.

J Am Soc Nephrol. 2000 Dec;11(12):2324-36.PMID: 11095655 [PubMed - indexed for MEDLINE]Related articlesFree article

AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-beta1 promoter in mesangial cells.

Weigert C, Sauer U, Brodbeck K, Pfeiffer A, Häring HU, Schleicher ED.

J Am Soc Nephrol. 2000 Nov;11(11):2007-16.PMID: 11053476 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of apoptosis by glyoxal in human embryonic lung epithelial cell line L132.

Kasper M, Roehlecke C, Witt M, Fehrenbach H, Hofer A, Miyata T, Weigert C, Funk RH, Schleicher ED.

Am J Respir Cell Mol Biol. 2000 Oct;23(4):485-91.PMID: 11017913 [PubMed - indexed for MEDLINE]Related articlesFree article