PubMed

GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients.

Mejia A, Schulz S, Hyslop T, Weinberg DS, Waldman SA.

Expert Rev Mol Diagn. 2009 Nov;9(8):777-85.PMID: 19895223 [PubMed - in process]Related articles

Chemiluminescence-based detection of gastrointestinal malignancies.

Park JY, Kirn TJ, Artis D, Waldman SA, Kricka LJ.

Luminescence. 2009 Oct 13. [Epub ahead of print]PMID: 19827005 [PubMed - as supplied by publisher]Related articles

Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas.

Winn B, Tavares R, Matoso A, Noble L, Fanion J, Waldman SA, Resnick MB.

Hum Pathol. 2009 Sep 30. [Epub ahead of print]PMID: 19800103 [PubMed - as supplied by publisher]Related articles

GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?

Li P, Lin JE, Marszlowicz GP, Valentino MA, Chang C, Schulz S, Pitari GM, Waldman SA.

Drug News Perspect. 2009 Jul-Aug;22(6):313-8.PMID: 19771320 [PubMed - in process]Related articles

The Hormone Receptor GUCY2C Suppresses Intestinal Tumor Formation by Inhibiting AKT Signaling.

Lin JE, Li P, Snook AE, Schulz S, Dasgupta A, Hyslop TM, Gibbons AV, Marszlowicz G, Pitari GM, Waldman SA.

Gastroenterology. 2009 Sep 6. [Epub ahead of print]PMID: 19737566 [PubMed - as supplied by publisher]Related articles

Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy.

Li P, Lin JE, Snook AE, Gibbons AV, Zuzga DS, Schulz S, Pitari GM, Waldman SA.

Clin Transl Sci. 2008 Sep 1;1(2):163-167.PMID: 19727435 [PubMed]Related articlesFree article

Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms.

Ciocca V, Bombonati A, Palazzo JP, Schulz S, Waldman SA.

Histopathology. 2009 Aug;55(2):182-8.PMID: 19694825 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.

Lin JE, Li P, Pitari GM, Schulz S, Waldman SA.

Future Oncol. 2009 May;5(4):509-22. Review.PMID: 19450179 [PubMed - indexed for MEDLINE]Related articles

Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.

Snook AE, Li P, Stafford BJ, Faul EJ, Huang L, Birbe RC, Bombonati A, Schulz S, Schnell MJ, Eisenlohr LC, Waldman SA.

Cancer Res. 2009 Apr 15;69(8):3537-44. Epub 2009 Apr 7.PMID: 19351847 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.

Lubbe WJ, Zuzga DS, Zhou Z, Fu W, Pelta-Heller J, Muschel RJ, Waldman SA, Pitari GM.

Cancer Res. 2009 Apr 15;69(8):3529-36. Epub 2009 Mar 31.PMID: 19336567 [PubMed - indexed for MEDLINE]Related articles

A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer.

Waldman SA, Terzic A.

FEBS J. 2009 Apr;276(8):2157-64. Epub 2009 Feb 25. Review.PMID: 19250312 [PubMed - indexed for MEDLINE]Related articles

Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.

Waldman SA, Hyslop T, Schulz S, Barkun A, Nielsen K, Haaf J, Bonaccorso C, Li Y, Weinberg DS.

JAMA. 2009 Feb 18;301(7):745-52.PMID: 19224751 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacoeconomics in the era of individualized medicine.

Waldman SA, Terzic A.

Clin Pharmacol Ther. 2008 Aug;84(2):179-82. No abstract available. PMID: 18679176 [PubMed - indexed for MEDLINE]Related articles

STa peptide analogs for probing guanylyl cyclase C.

Tian X, Michal AM, Li P, Wolfe HR, Waldman SA, Wickstrom E.

Biopolymers. 2008;90(5):713-23.PMID: 18615494 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.

Snook AE, Stafford BJ, Li P, Tan G, Huang L, Birbe R, Schulz S, Schnell MJ, Thakur M, Rothstein JL, Eisenlohr LC, Waldman SA.

J Natl Cancer Inst. 2008 Jul 2;100(13):950-61. Epub 2008 Jun 24.PMID: 18577748 [PubMed - indexed for MEDLINE]Related articlesFree article

Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells.

Pitari GM, Lin JE, Shah FJ, Lubbe WJ, Zuzga DS, Li P, Schulz S, Waldman SA.

Carcinogenesis. 2008 Aug;29(8):1601-7. Epub 2008 Jun 19.PMID: 18566015 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNA signatures as diagnostic and therapeutic targets.

Waldman SA, Terzic A.

Clin Chem. 2008 Jun;54(6):943-4. No abstract available. PMID: 18509012 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic targeting: a crucible for individualized medicine.

Waldman SA, Terzic A.

Clin Pharmacol Ther. 2008 May;83(5):651-4. No abstract available. PMID: 18425084 [PubMed - indexed for MEDLINE]Related articles

Derivation and fluidity of acutely induced dysfunctional CD8+ T cells.

Plesa G, Snook AE, Waldman SA, Eisenlohr LC.

J Immunol. 2008 Apr 15;180(8):5300-8.PMID: 18390711 [PubMed - indexed for MEDLINE]Related articlesFree article

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

Li P, Lin JE, Chervoneva I, Schulz S, Waldman SA, Pitari GM.

Am J Pathol. 2007 Dec;171(6):1847-58. Epub 2007 Nov 1.PMID: 17974601 [PubMed - indexed for MEDLINE]Related articlesFree article

Individualized medicine and the imperative of global health.

Waldman SA, Terzic A.

Clin Pharmacol Ther. 2007 Nov;82(5):479-83. No abstract available. PMID: 17952097 [PubMed - indexed for MEDLINE]Related articles

Cancer mucosa antigens as a novel immunotherapeutic class of tumor-associated antigen.

Snook AE, Eisenlohr LC, Rothstein JL, Waldman SA.

Clin Pharmacol Ther. 2007 Dec;82(6):734-9. Epub 2007 Sep 26. Review.PMID: 17898707 [PubMed - indexed for MEDLINE]Related articles

Molecular medicine hones therapeutic arts to science.

Waldman SA, Terzic MR, Terzic A.

Clin Pharmacol Ther. 2007 Oct;82(4):343-7. No abstract available. PMID: 17851568 [PubMed - indexed for MEDLINE]Related articles

Acquired and innate cardioprotection.

Terzic A, Moore RL, Waldman SA.

J Appl Physiol. 2007 Oct;103(4):1436-7. Epub 2007 Aug 9. No abstract available. PMID: 17690193 [PubMed - indexed for MEDLINE]Related articlesFree article

The paracrine hormone hypothesis of colorectal cancer.

Pitari GM, Li P, Lin JE, Zuzga D, Gibbons AV, Snook AE, Schulz S, Waldman SA.

Clin Pharmacol Ther. 2007 Oct;82(4):441-7. Epub 2007 Aug 8. Review.PMID: 17687268 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.

Li P, Schulz S, Bombonati A, Palazzo JP, Hyslop TM, Xu Y, Baran AA, Siracusa LD, Pitari GM, Waldman SA.

Gastroenterology. 2007 Aug;133(2):599-607. Epub 2007 Jun 2.PMID: 17681179 [PubMed - indexed for MEDLINE]Related articles

Translating MicroRNA discovery into clinical biomarkers in cancer.

Waldman SA, Terzic A.

JAMA. 2007 May 2;297(17):1923-5. No abstract available. PMID: 17473304 [PubMed - indexed for MEDLINE]Related articles

H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter.

de Godoy MA, Patel CA, Waldman SA, Katsuki M, Regan RF, Rattan S.

Gastroenterology. 2007 Apr;132(4):1401-9. Epub 2007 Jan 26.PMID: 17408635 [PubMed - indexed for MEDLINE]Related articles

The pharmacokinetics of taurolidine metabolites in healthy volunteers.

Gong L, Greenberg HE, Perhach JL, Waldman SA, Kraft WK.

J Clin Pharmacol. 2007 Jun;47(6):697-703. Epub 2007 Mar 29.PMID: 17395893 [PubMed - indexed for MEDLINE]Related articles

Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer.

Fortina P, Kricka LJ, Graves DJ, Park J, Hyslop T, Tam F, Halas N, Surrey S, Waldman SA.

Trends Biotechnol. 2007 Apr;25(4):145-52. Epub 2007 Feb 21. Review.PMID: 17316852 [PubMed - indexed for MEDLINE]Related articles

Biomarker development, commercialization, and regulation: individualization of medicine lost in translation.

Wilson C, Schulz S, Waldman SA.

Clin Pharmacol Ther. 2007 Feb;81(2):153-5. No abstract available. PMID: 17259939 [PubMed - indexed for MEDLINE]Related articles

Clinical pharmacology: the science of therapeutics.

Waldman SA, Christensen NB, Moore JE, Terzic A.

Clin Pharmacol Ther. 2007 Jan;81(1):3-6. No abstract available. PMID: 17185986 [PubMed - indexed for MEDLINE]Related articles

Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells.

Waldman SA, Fortina P, Surrey S, Hyslop T, Kricka LJ, Graves DJ.

Future Oncol. 2006 Dec;2(6):705-16. Review.PMID: 17155897 [PubMed - indexed for MEDLINE]Related articles

A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer.

Schulz S, Hyslop T, Haaf J, Bonaccorso C, Nielsen K, Witek ME, Birbe R, Palazzo J, Weinberg D, Waldman SA.

Clin Cancer Res. 2006 Aug 1;12(15):4545-52.PMID: 16899600 [PubMed - indexed for MEDLINE]Related articlesFree article

Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.

Pitari GM, Li T, Baksh RI, Waldman SA.

Mol Cancer Ther. 2006 May;5(5):1190-6.PMID: 16731751 [PubMed - indexed for MEDLINE]Related articlesFree article

Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.

Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Cell C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA.

Gastroenterology. 2006 Apr;130(4):1191-206.PMID: 16618413 [PubMed - indexed for MEDLINE]Related articles

Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.

Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM.

Clin Cancer Res. 2006 Mar 15;12(6):1876-82.PMID: 16551873 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers.

Majumdar AK, Howard L, Goldberg MR, Hickey L, Constanzer M, Rothenberg PL, Crumley TM, Panebianco D, Bradstreet TE, Bergman AJ, Waldman SA, Greenberg HE, Butler K, Knops A, De Lepeleire I, Michiels N, Petty KJ.

J Clin Pharmacol. 2006 Mar;46(3):291-300.PMID: 16490805 [PubMed - indexed for MEDLINE]Related articles

The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.

Witek ME, Nielsen K, Walters R, Hyslop T, Palazzo J, Schulz S, Waldman SA.

Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8549-56.PMID: 16361536 [PubMed - indexed for MEDLINE]Related articlesFree article

Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.

Pitari GM, Baksh RI, Harris DM, Li P, Kazerounian S, Waldman SA.

Cancer Res. 2005 Dec 1;65(23):11129-35.PMID: 16322263 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor-targeting peptide-PNA-peptide chimeras for imaging overexpressed oncogene mRNAs.

Tian X, Aruva MR, Wolfe HR, Qin W, Sauter ER, Thakur ML, Waldman SA, Wickstrom E.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):1085-91.PMID: 16248097 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer.

Frick GS, Pitari GM, Weinberg DS, Hyslop T, Schulz S, Waldman SA.

Expert Rev Mol Diagn. 2005 Sep;5(5):701-13. Review.PMID: 16149873 [PubMed - indexed for MEDLINE]Related articles

Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.

Kazerounian S, Pitari GM, Shah FJ, Frick GS, Madesh M, Ruiz-Stewart I, Schulz S, Hajnóczky G, Waldman SA.

J Pharmacol Exp Ther. 2005 Sep;314(3):1013-22. Epub 2005 Jun 3.PMID: 15937149 [PubMed - indexed for MEDLINE]Related articlesFree article

Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.

Birbe R, Palazzo JP, Walters R, Weinberg D, Schulz S, Waldman SA.

Hum Pathol. 2005 Feb;36(2):170-9.PMID: 15754294 [PubMed - indexed for MEDLINE]Related articles

Markers of cell cycle-mediated drug resistance and prognosis of patients receiving preoperative combined modality therapy for rectal cancer.

Waldman SA.

Ann Surg Oncol. 2004 Nov;11(11):949-50. No abstract available. PMID: 15525820 [PubMed - indexed for MEDLINE]Related articles

Potential for interactions between caspofungin and nelfinavir or rifampin.

Stone JA, Migoya EM, Hickey L, Winchell GA, Deutsch PJ, Ghosh K, Freeman A, Bi S, Desai R, Dilzer SC, Lasseter KC, Kraft WK, Greenberg H, Waldman SA.

Antimicrob Agents Chemother. 2004 Nov;48(11):4306-14.PMID: 15504857 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.

Agrawal NG, Matthews CZ, Mazenko RS, Woolf EJ, Porras AG, Chen X, Miller JL, Michiels N, Wehling M, Schultz A, Gottlieb AB, Kraft WK, Greenberg HE, Waldman SA, Curtis SP, Gottesdiener KM.

J Clin Pharmacol. 2004 Oct;44(10):1125-31.PMID: 15342613 [PubMed - indexed for MEDLINE]Related articles

Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP.

Tiyyagura SR, Kazerounian S, Schulz S, Waldman SA, Pitari GM.

Vitam Horm. 2004;69:69-94. Review.PMID: 15196879 [PubMed - indexed for MEDLINE]Related articles

Indinavir and rifabutin drug interactions in healthy volunteers.

Kraft WK, McCrea JB, Winchell GA, Carides A, Lowry R, Woolf EJ, Kusma SE, Deutsch PJ, Greenberg HE, Waldman SA.

J Clin Pharmacol. 2004 Mar;44(3):305-13.PMID: 14973305 [PubMed - indexed for MEDLINE]Related articles

Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.

Ruiz-Stewart I, Tiyyagura SR, Lin JE, Kazerounian S, Pitari GM, Schulz S, Martin E, Murad F, Waldman SA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):37-42. Epub 2003 Dec 18.PMID: 14684830 [PubMed - indexed for MEDLINE]Related articlesFree article