PubMed

Genetic variation in PARL influences mitochondrial content.

Curran JE, Jowett JB, Abraham LJ, Diepeveen LA, Elliott KS, Dyer TD, Kerr-Bayles LJ, Johnson MP, Comuzzie AG, Moses EK, Walder KR, Collier GR, Blangero J, Kissebah AH.

Hum Genet. 2009 Oct 28. [Epub ahead of print]PMID: 19862556 [PubMed - as supplied by publisher]Related articles

Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus.

Molero JC, Lee S, Leizerman I, Chajut A, Cooper A, Walder K.

Biochim Biophys Acta. 2009 Oct 14. [Epub ahead of print]PMID: 19835953 [PubMed - as supplied by publisher]Related articles

Identification of secreted proteins associated with obesity and type 2 diabetes in Psammomys obesus.

Bolton K, Segal D, McMillan J, Sanigorski A, Collier G, Walder K.

Int J Obes (Lond). 2009 Oct;33(10):1153-65. Epub 2009 Jul 28.PMID: 19636319 [PubMed - in process]Related articles

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity.

Su H, Gunter JH, de Vries M, Connor T, Wanyonyi S, Newell FS, Segal D, Molero JC, Reizes O, Prins JB, Hutley LJ, Walder K, Whitehead JP.

Biochem Biophys Res Commun. 2009 Aug 21;386(2):351-5. Epub 2009 Jun 11.PMID: 19523919 [PubMed - indexed for MEDLINE]Related articles

Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population.

Bozaoglu K, Segal D, Shields KA, Cummings N, Curran JE, Comuzzie AG, Mahaney MC, Rainwater DL, VandeBerg JL, MacCluer JW, Collier G, Blangero J, Walder K, Jowett JB.

J Clin Endocrinol Metab. 2009 Aug;94(8):3085-8. Epub 2009 May 26.PMID: 19470637 [PubMed - indexed for MEDLINE]Related articles

NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors.

Foletta VC, Prior MJ, Stupka N, Carey K, Segal DH, Jones S, Swinton C, Martin S, Cameron-Smith D, Walder KR.

J Physiol. 2009 Apr 1;587(Pt 7):1619-34. Epub 2009 Feb 9.PMID: 19204049 [PubMed - indexed for MEDLINE]Related articles

Decorin is a secreted protein associated with obesity and type 2 diabetes.

Bolton K, Segal D, McMillan J, Jowett J, Heilbronn L, Abberton K, Zimmet P, Chisholm D, Collier G, Walder K.

Int J Obes (Lond). 2008 Jul;32(7):1113-21. Epub 2008 Apr 15.PMID: 18414424 [PubMed - indexed for MEDLINE]Related articles

Chemerin is a novel adipokine associated with obesity and metabolic syndrome.

Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, Collier G, Walder K, Segal D.

Endocrinology. 2007 Oct;148(10):4687-94. Epub 2007 Jul 19.PMID: 17640997 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretion of the glucose-regulated selenoprotein SEPS1 from hepatoma cells.

Gao Y, Pagnon J, Feng HC, Konstantopolous N, Jowett JB, Walder K, Collier GR.

Biochem Biophys Res Commun. 2007 May 11;356(3):636-41. Epub 2007 Mar 12.PMID: 17374524 [PubMed - indexed for MEDLINE]Related articles

SEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosis.

Kim KH, Gao Y, Walder K, Collier GR, Skelton J, Kissebah AH.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):127-32. Epub 2007 Jan 2.PMID: 17210132 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization and expression of selenoprotein S in the testis of Psammomys obesus.

Windmill K, Tenne-Brown J, Bayles R, Trevaskis J, Gao Y, Walder K, Collier GR.

J Mol Histol. 2007 Mar;38(1):97-101. Epub 2006 Dec 16.PMID: 17180443 [PubMed - indexed for MEDLINE]Related articles

Association of genetic variation within UBL5 with phenotypes of metabolic syndrome.

Bozaoglu K, Curran JE, Elliott KS, Walder KR, Dyer TD, Rainwater DL, VandeBerg JL, Comuzzie AG, Collier GR, Zimmet P, MacCluer JW, Jowett JB, Blangero J.

Hum Biol. 2006 Apr;78(2):147-59.PMID: 17036923 [PubMed - indexed for MEDLINE]Related articles

Identification of novel genes expressed during rhabdomyosarcoma differentiation using cDNA microarrays.

Carey KA, Segal D, Klein R, Sanigorski A, Walder K, Collier GR, Cameron-Smith D.

Pathol Int. 2006 May;56(5):246-55.PMID: 16669873 [PubMed - indexed for MEDLINE]Related articles

Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells.

Gao Y, Hannan NR, Wanyonyi S, Konstantopolous N, Pagnon J, Feng HC, Jowett JB, Kim KH, Walder K, Collier GR.

Cytokine. 2006 Mar 7;33(5):246-51. Epub 2006 Mar 30.PMID: 16574427 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in selenoprotein S influences inflammatory response.

Curran JE, Jowett JB, Elliott KS, Gao Y, Gluschenko K, Wang J, Abel Azim DM, Cai G, Mahaney MC, Comuzzie AG, Dyer TD, Walder KR, Zimmet P, MacCluer JW, Collier GR, Kissebah AH, Blangero J.

Nat Genet. 2005 Nov;37(11):1234-41. Epub 2005 Oct 9.PMID: 16227999 [PubMed - indexed for MEDLINE]Related articles

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.

Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.

FASEB J. 2005 Dec;19(14):2072-4. Epub 2005 Oct 3. Retraction in: FASEB J. 2009 Aug;23(8):2790. PMID: 16203862 [PubMed - indexed for MEDLINE]Related articlesFree article

Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance.

Trevaskis J, Walder K, Foletta V, Kerr-Bayles L, McMillan J, Cooper A, Lee S, Bolton K, Prior M, Fahey R, Whitecross K, Morton GJ, Schwartz MW, Collier GR.

Endocrinology. 2005 Sep;146(9):3757-64. Epub 2005 May 26.PMID: 15919751 [PubMed - indexed for MEDLINE]Related articlesFree article

The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes.

Walder K, Kerr-Bayles L, Civitarese A, Jowett J, Curran J, Elliott K, Trevaskis J, Bishara N, Zimmet P, Mandarino L, Ravussin E, Blangero J, Kissebah A, Collier GR.

Diabetologia. 2005 Mar;48(3):459-68. Epub 2005 Feb 24.PMID: 15729572 [PubMed - indexed for MEDLINE]Related articles

c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action.

Molero JC, Jensen TE, Withers PC, Couzens M, Herzog H, Thien CB, Langdon WY, Walder K, Murphy MA, Bowtell DD, James DE, Cooney GJ.

J Clin Invest. 2004 Nov;114(9):1326-33.PMID: 15520865 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2.

Collier FM, Gregorio-King CC, Gough TJ, Talbot CD, Walder K, Kirkland MA.

Biochem Biophys Res Commun. 2004 Nov 26;324(4):1360-9.PMID: 15504364 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in BEACON influences quantitative variation in metabolic syndrome-related phenotypes.

Jowett JB, Elliott KS, Curran JE, Hunt N, Walder KR, Collier GR, Zimmet PZ, Blangero J.

Diabetes. 2004 Sep;53(9):2467-72.PMID: 15331561 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic reticulum stress - SelS is a novel glucose-regulated protein.

Gao Y, Feng HC, Walder K, Bolton K, Sunderland T, Bishara N, Quick M, Kantham L, Collier GR.

FEBS Lett. 2004 Apr 9;563(1-3):185-90.PMID: 15063746 [PubMed - indexed for MEDLINE]Related articles

Identification of hypothalamic genes implicated in the development of obesity in Psammomys obesus using differential display PCR.

Trevaskis J, McMillan JS, Windmill K, Walder K, Collier GR.

Comp Biochem Physiol B Biochem Mol Biol. 2004 Jan;137(1):65-73.PMID: 14698911 [PubMed - indexed for MEDLINE]Related articles

The Taq IA and Ser311 Cys polymorphisms in the dopamine D2 receptor gene and obesity.

Southon A, Walder K, Sanigorski AM, Zimmet P, Nicholson GC, Kotowicz MA, Collier G.

Diabetes Nutr Metab. 2003 Feb;16(1):72-6.PMID: 12848308 [PubMed - indexed for MEDLINE]Related articles

Obesity and diabetes gene discovery approaches.

Walder K, Segal D, Jowett J, Blangero J, Collier GR.

Curr Pharm Des. 2003;9(17):1357-72. Review.PMID: 12769728 [PubMed - indexed for MEDLINE]Related articles

Beacon interacts with cdc2/cdc28-like kinases.

Kantham L, Kerr-Bayles L, Godde N, Quick M, Webb R, Sunderland T, Bond J, Walder K, Augert G, Collier G.

Biochem Biophys Res Commun. 2003 Apr 25;304(1):125-9.PMID: 12705895 [PubMed - indexed for MEDLINE]Related articles

Elevation in Tanis expression alters glucose metabolism and insulin sensitivity in H4IIE cells.

Gao Y, Walder K, Sunderland T, Kantham L, Feng HC, Quick M, Bishara N, de Silva A, Augert G, Tenne-Brown J, Collier GR.

Diabetes. 2003 Apr;52(4):929-34.PMID: 12663463 [PubMed - indexed for MEDLINE]Related articlesFree article

ORP3 splice variants and their expression in human tissues and hematopoietic cells.

Collier FM, Gregorio-King CC, Apostolopoulos J, Walder K, Kirkland MA.

DNA Cell Biol. 2003 Jan;22(1):1-9.PMID: 12590732 [PubMed - indexed for MEDLINE]Related articles

New approaches to gene discovery with animal models of obesity and diabetes.

Collier G, Walder K, De Silva A, Tenne-Brown J, Sanigorski A, Segal D, Kantham L, Augert G.

Ann N Y Acad Sci. 2002 Jun;967:403-13. Review.PMID: 12079868 [PubMed - indexed for MEDLINE]Related articles

A custom-built insulin resistance gene chip.

Walder K, Segal D, Chehab S, Augert G, Cameron-Smith D, Hargreaves M, Collier GR.

Ann N Y Acad Sci. 2002 Jun;967:274-82.PMID: 12079855 [PubMed - indexed for MEDLINE]Related articles

Calpain 3 gene expression in skeletal muscle is associated with body fat content and measures of insulin resistance.

Walder K, McMillan J, Lapsys N, Kriketos A, Trevaskis J, Civitarese A, Southon A, Zimmet P, Collier G.

Int J Obes Relat Metab Disord. 2002 Apr;26(4):442-9.PMID: 12075569 [PubMed - indexed for MEDLINE]Related articles

Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetes.

Walder K, Ziv E, Kalman R, Whitecross K, Shafrir E, Zimmet P, Collier GR.

Int J Obes Relat Metab Disord. 2002 May;26(5):605-9.PMID: 12032742 [PubMed - indexed for MEDLINE]Related articlesFree article

Tanis: a link between type 2 diabetes and inflammation?

Walder K, Kantham L, McMillan JS, Trevaskis J, Kerr L, De Silva A, Sunderland T, Godde N, Gao Y, Bishara N, Windmill K, Tenne-Brown J, Augert G, Zimmet PZ, Collier GR.

Diabetes. 2002 Jun;51(6):1859-66.PMID: 12031974 [PubMed - indexed for MEDLINE]Related articlesFree article

Profile of dyslipidemia in Psammomys obesus, an animal model of the metabolic syndrome.

Walder K, Oakes N, Fahey RP, Cooney G, Zimmet PZ, Collier GR.

Endocr Regul. 2002 Mar;36(1):1-8.PMID: 11971745 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation and obesity in Australian women: a prospective study.

de Silva AM, Walder KR, Boyko EJ, Whitecross KF, Nicholson G, Kotowicz M, Pasco J, Collier GR.

Obes Res. 2001 Dec;9(12):733-40.PMID: 11743056 [PubMed - indexed for MEDLINE]Related articles

Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats).

Walder K, McMillan JS, Lee S, Civitarese A, Zimmet P, Collier GR.

Int J Obes Relat Metab Disord. 2001 Sep;25(9):1281-5.PMID: 11571588 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of obesity phenotypes in Psammomys obesus (Israeli sand rats).

Walder KR, Fahey RP, Morton GJ, Zimmet PZ, Collier GR.

Int J Exp Diabetes Res. 2000;1(3):177-84.PMID: 11467408 [PubMed - indexed for MEDLINE]Related articlesFree article

AFLP fingerprinting of the human genome.

Prochazka M, Walder K, Xia J.

Hum Genet. 2001 Jan;108(1):59-65.PMID: 11214909 [PubMed - indexed for MEDLINE]Related articles

Beacon: a novel gene involved in the regulation of energy balance.

Collier GR, McMillan JS, Windmill K, Walder K, Tenne-Brown J, de Silva A, Trevaskis J, Jones S, Morton GJ, Lee S, Augert G, Civitarese A, Zimmet PZ.

Diabetes. 2000 Nov;49(11):1766-71.PMID: 11078442 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians.

Jenkinson CP, Cray K, Walder K, Herzog H, Hanson, Ravussin E.

Int J Obes Relat Metab Disord. 2000 May;24(5):580-4.PMID: 10849579 [PubMed - indexed for MEDLINE]Related articles

An autosomal genomic scan for loci linked to plasma leptin concentration in Pima Indians.

Walder K, Hanson RL, Kobes S, Knowler WC, Ravussin E.

Int J Obes Relat Metab Disord. 2000 May;24(5):559-65.PMID: 10849576 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the gene encoding CART is not associated with obesity in Pima Indians.

Walder K, Morris C, Ravussin E.

Int J Obes Relat Metab Disord. 2000 Apr;24(4):520-1.PMID: 10805512 [PubMed - indexed for MEDLINE]Related articles

A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians.

Schrauwen P, Xia J, Walder K, Snitker S, Ravussin E.

Int J Obes Relat Metab Disord. 1999 Dec;23(12):1242-5.PMID: 10643679 [PubMed - indexed for MEDLINE]Related articles

Impact of obesity and leptin treatment on adipocyte gene expression in Psammomys obesus.

Sanigorski A, Cameron-Smith D, Lewandowski P, Walder K, de Silva A, Morton G, Collier GR.

J Endocrinol. 2000 Jan;164(1):45-50.PMID: 10607936 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males.

de Silva AM, Walder KR, Aitman TJ, Gotoda T, Goldstone AP, Hodge AM, de Courten MP, Zimmet PZ, Collier GR.

Int J Obes Relat Metab Disord. 1999 Aug;23(8):816-22.PMID: 10490782 [PubMed - indexed for MEDLINE]Related articles

Leptin resistance in a polygenic, hyperleptinemic animal model of obesity and NIDDM: Psammomys obesus.

Walder K, Lewandowski P, Morton G, Sanigorski A, de Silva A, Zimmet P, Collier GR.

Int J Obes Relat Metab Disord. 1999 Jan;23(1):83-9.PMID: 10094582 [PubMed - indexed for MEDLINE]Related articles

Human uncoupling proteins and obesity.

Schrauwen P, Walder K, Ravussin E.

Obes Res. 1999 Jan;7(1):97-105. Review.PMID: 10023736 [PubMed - indexed for MEDLINE]Related articles

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP, Easlick J, Warden CH, Pecqueur C, Raimbault S, Ricquier D, Silver MH, Shuldiner AR, Solanes G, Lowell BB, Chung WK, Leibel RL, Pratley R, Ravussin E.

Hum Mol Genet. 1998 Sep;7(9):1431-5.PMID: 9700198 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin inhibits insulin binding in isolated rat adipocytes.

Walder K, Filippis A, Clark S, Zimmet P, Collier GR.

J Endocrinol. 1997 Dec;155(3):R5-7.PMID: 9488006 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulation of leptin in response to fasting in insulin-resistant Psammomys obesus (Israeli sand rats).

Walder K, Lee S, Zimmet P, Collier GR.

Metabolism. 1998 Jan;47(1):125-8.PMID: 9440491 [PubMed - indexed for MEDLINE]Related articles