PubMed

Precise determination of glucose-d(2)/glucose ratio in human serum and plasma by APCI LC-MS/MS.

Ullah S, Wahren J, Beck O.

Scand J Clin Lab Invest. 2009 Nov 23. [Epub ahead of print]PMID: 19929275 [PubMed - as supplied by publisher]

New tricks by an old dog.

Forst T, Wahren J.

Exp Diabetes Res. 2008;2008:384219. No abstract available. PMID: 18810274 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide and its C-terminal fragments improve erythrocyte deformability in type 1 diabetes patients.

Hach T, Forst T, Kunt T, Ekberg K, Pfützner A, Wahren J.

Exp Diabetes Res. 2008;2008:730594.PMID: 18483566 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism.

Lövgren-Sandblom A, Heverin M, Larsson H, Lundström E, Wahren J, Diczfalusy U, Björkhem I.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):15-9. Epub 2007 May 29.PMID: 17561450 [PubMed - indexed for MEDLINE]Related articles

Splanchnic regulation of glucose production.

Wahren J, Ekberg K.

Annu Rev Nutr. 2007;27:329-45. Review.PMID: 17465853 [PubMed - indexed for MEDLINE]Related articles

Cellular internalization of proinsulin C-peptide.

Lindahl E, Nyman U, Melles E, Sigmundsson K, Ståhlberg M, Wahren J, Obrink B, Shafqat J, Joseph B, Jörnvall H.

Cell Mol Life Sci. 2007 Feb;64(4):479-86.PMID: 17279313 [PubMed - indexed for MEDLINE]Related articles

Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.

Meaney S, Heverin M, Panzenboeck U, Ekström L, Axelsson M, Andersson U, Diczfalusy U, Pikuleva I, Wahren J, Sattler W, Björkhem I.

J Lipid Res. 2007 Apr;48(4):944-51. Epub 2007 Jan 24.PMID: 17251592 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide is a bioactive peptide.

Wahren J, Ekberg K, Jörnvall H.

Diabetologia. 2007 Mar;50(3):503-9. Epub 2007 Jan 18. No abstract available. PMID: 17235526 [PubMed - indexed for MEDLINE]Related articles

C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy.

Ekberg K, Brismar T, Johansson BL, Lindström P, Juntti-Berggren L, Norrby A, Berne C, Arnqvist HJ, Bolinder J, Wahren J.

Diabetes Care. 2007 Jan;30(1):71-6.PMID: 17192336 [PubMed - indexed for MEDLINE]Related articlesFree article

C-Peptide reverses nociceptive neuropathy in type 1 diabetes.

Kamiya H, Zhang W, Ekberg K, Wahren J, Sima AA.

Diabetes. 2006 Dec;55(12):3581-7.PMID: 17130507 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide improves neuropathy in type 1 diabetic BB/Wor-rats.

Zhang W, Kamiya H, Ekberg K, Wahren J, Sima AA.

Diabetes Metab Res Rev. 2007 Jan;23(1):63-70.PMID: 16845685 [PubMed - indexed for MEDLINE]Related articles

Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects.

Shafqat J, Melles E, Sigmundsson K, Johansson BL, Ekberg K, Alvelius G, Henriksson M, Johansson J, Wahren J, Jörnvall H.

Cell Mol Life Sci. 2006 Aug;63(15):1805-11.PMID: 16845606 [PubMed - indexed for MEDLINE]Related articlesFree article

Large-surface biosensor technology for enhanced recovery in protein characterization.

Melles E, Bergman T, Ståhlberg M, Thirstrup C, Wahren J, Jörnvall H, Shafqat J.

J Biomol Tech. 2005 Dec;16(4):392-7.PMID: 16522861 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of C-peptide on early glomerular changes in diabetic mice.

Maezawa Y, Yokote K, Sonezaki K, Fujimoto M, Kobayashi K, Kawamura H, Tokuyama T, Takemoto M, Ueda S, Kuwaki T, Mori S, Wahren J, Saito Y.

Diabetes Metab Res Rev. 2006 Jul-Aug;22(4):313-22.PMID: 16389646 [PubMed - indexed for MEDLINE]Related articles

Separate functional features of proinsulin C-peptide.

Henriksson M, Nordling E, Melles E, Shafqat J, Ståhlberg M, Ekberg K, Persson B, Bergman T, Wahren J, Johansson J, Jörnvall H.

Cell Mol Life Sci. 2005 Aug;62(15):1772-8.PMID: 16003487 [PubMed - indexed for MEDLINE]Related articles

Early microvascular dysfunction in healthy normal-weight males with heredity for type 2 diabetes.

Jörneskog G, Kalani M, Kuhl J, Båvenholm P, Katz A, Allerstrand G, Alvarsson M, Efendic S, Ostenson CG, Pernow J, Wahren J, Brismar K.

Diabetes Care. 2005 Jun;28(6):1495-7. No abstract available. PMID: 15920077 [PubMed - indexed for MEDLINE]Related articlesFree article

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

Heverin M, Meaney S, Lütjohann D, Diczfalusy U, Wahren J, Björkhem I.

J Lipid Res. 2005 May;46(5):1047-52. Epub 2005 Mar 1.PMID: 15741649 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide prevents glomerular hypertrophy and mesangial matrix expansion in diabetic rats.

Samnegård B, Jacobson SH, Jaremko G, Johansson BL, Ekberg K, Isaksson B, Eriksson L, Wahren J, Sjöquist M.

Nephrol Dial Transplant. 2005 Mar;20(3):532-8. Epub 2005 Jan 21.PMID: 15665028 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells.

Zhong Z, Davidescu A, Ehrén I, Ekberg K, Jörnvall H, Wahren J, Chibalin AV.

Diabetologia. 2005 Jan;48(1):187-97. Epub 2004 Dec 29.PMID: 15624099 [PubMed - indexed for MEDLINE]Related articles

Degradation of proinsulin C-peptide in kidney and placenta extracts by a specific endoprotease activity.

Melles E, Jörnvall H, Tryggvason S, Danielsson KG, Ekberg K, Tryggvason K, Wahren J, Bergman T.

Cell Mol Life Sci. 2004 Dec;61(23):2979-82.PMID: 15583859 [PubMed - indexed for MEDLINE]Related articles

C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells.

Zhong Z, Kotova O, Davidescu A, Ehrén I, Ekberg K, Jörnvall H, Wahren J, Chibalin AV.

Cell Mol Life Sci. 2004 Nov;61(21):2782-90.PMID: 15549182 [PubMed - indexed for MEDLINE]Related articles

C-peptide: new findings and therapeutic implications in diabetes.

Wahren J.

Clin Physiol Funct Imaging. 2004 Jul;24(4):180-9. Review.PMID: 15233831 [PubMed - indexed for MEDLINE]Related articles

Molecular and cellular effects of C-peptide--new perspectives on an old peptide.

Wahren J, Shafqat J, Johansson J, Chibalin A, Ekberg K, Jörnvall H.

Exp Diabesity Res. 2004 Jan-Mar;5(1):15-23. Review.PMID: 15198368 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide fragments stimulate glucose utilization in diabetic rats.

Sato Y, Oshida Y, Han YQ, Morishita Y, Li L, Ekberg K, Jörnvall H, Wahren J.

Cell Mol Life Sci. 2004 Mar;61(6):727-32.PMID: 15052415 [PubMed - indexed for MEDLINE]Related articles

C-peptide and captopril are equally effective in lowering glomerular hyperfiltration in diabetic rats.

Samnegård B, Jacobson SH, Johansson BL, Ekberg K, Isaksson B, Wahren J, Sjöquist M.

Nephrol Dial Transplant. 2004 Jun;19(6):1385-91. Epub 2004 Mar 5.PMID: 15004258 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct measurements of the permeability surface area for insulin and glucose in human skeletal muscle.

Gudbjörnsdóttir S, Sjöstrand M, Strindberg L, Wahren J, Lönnroth P.

J Clin Endocrinol Metab. 2003 Oct;88(10):4559-64.PMID: 14557422 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients.

Johansson BL, Sundell J, Ekberg K, Jonsson C, Seppänen M, Raitakari O, Luotolahti M, Nuutila P, Wahren J, Knuuti J.

Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E14-9. Epub 2003 Sep 3.PMID: 12954595 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide makes a comeback.

Wahren J, Jörnvall H.

Diabetes Metab Res Rev. 2003 Sep-Oct;19(5):345-7. Review.PMID: 12951641 [PubMed - indexed for MEDLINE]Related articles

Effects of proinsulin C-peptide in experimental diabetic neuropathy: vascular actions and modulation by nitric oxide synthase inhibition.

Cotter MA, Ekberg K, Wahren J, Cameron NE.

Diabetes. 2003 Jul;52(7):1812-7.PMID: 12829651 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin C-peptide and its C-terminal pentapeptide: degradation in human serum and Schiff base formation with subsequent CO2 incorporation.

Melles E, Bergman T, Alvelius G, Jonsson A, Ekberg K, Wahren J, Jörnvall H.

Cell Mol Life Sci. 2003 May;60(5):1019-25.PMID: 12827290 [PubMed - indexed for MEDLINE]Related articles

C-peptide increases forearm blood flow in patients with type 1 diabetes via a nitric oxide-dependent mechanism.

Johansson BL, Wahren J, Pernow J.

Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E864-70. Epub 2003 Jun 10.PMID: 12799312 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide: a new potential in the treatment of diabetic nephropathy.

Wahren J, Ekberg K, Samnegård B, Johansson BL.

Curr Diab Rep. 2001 Dec;1(3):261-6. Review.PMID: 12643208 [PubMed - indexed for MEDLINE]Related articles

Amelioration of sensory nerve dysfunction by C-Peptide in patients with type 1 diabetes.

Ekberg K, Brismar T, Johansson BL, Jonsson B, Lindström P, Wahren J.

Diabetes. 2003 Feb;52(2):536-41.PMID: 12540632 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin C-peptide--a consensus statement.

Sima AA, Grunberger G, Jörnvall H, Wahren J; C-peptide Study Group.

Int J Exp Diabetes Res. 2001;2(2):145-51. Review.PMID: 12369718 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide exerts beneficial effects on myocardial blood flow and function in patients with type 1 diabetes.

Hansen A, Johansson BL, Wahren J, von Bibra H.

Diabetes. 2002 Oct;51(10):3077-82.PMID: 12351450 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal tubular cells.

Shafqat J, Juntti-Berggren L, Zhong Z, Ekberg K, Köhler M, Berggren PO, Johansson J, Wahren J, Jörnvall H.

Cell Mol Life Sci. 2002 Jul;59(7):1185-9.PMID: 12222964 [PubMed - indexed for MEDLINE]Related articles

[Actions of the tobacco industry and Swedish physicians]

Wahren J.

Lakartidningen. 2002 Jun 27;99(26-27):2974. Swedish. No abstract available. PMID: 12170694 [PubMed - indexed for MEDLINE]Related articles

Molecular effects of proinsulin C-peptide.

Johansson J, Ekberg K, Shafqat J, Henriksson M, Chibalin A, Wahren J, Jörnvall H.

Biochem Biophys Res Commun. 2002 Aug 2;295(5):1035-40. Review.PMID: 12135597 [PubMed - indexed for MEDLINE]Related articles

In vivo biodistribution and pharmacokinetics of (18)F-labeled human C-peptide: evaluation in monkeys using positron emission tomography.

Fredriksson A, Ekberg K, Ingvar M, Johansson BL, Wahren J, Stone-Elander S.

Life Sci. 2002 Aug 9;71(12):1361-70.PMID: 12127157 [PubMed - indexed for MEDLINE]Related articles

Splanchnic blood flow and oxygen uptake during cardiopulmonary bypass.

Gårdebäck M, Settergren G, Brodin LA, Jorfeldt L, Galuska D, Ekberg K, Wahren J.

J Cardiothorac Vasc Anesth. 2002 Jun;16(3):308-15.PMID: 12073202 [PubMed - indexed for MEDLINE]Related articles

Insulin binding monitored by fluorescence correlation spectroscopy.

Zhong ZH, Pramanik A, Ekberg K, Jansson OT, Jörnvall H, Wahren J, Rigler R.

Diabetologia. 2001 Sep;44(9):1184-8.PMID: 11596675 [PubMed - indexed for MEDLINE]Related articles

C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat.

Sima AA, Zhang W, Sugimoto K, Henry D, Li Z, Wahren J, Grunberger G.

Diabetologia. 2001 Jul;44(7):889-97.PMID: 11508275 [PubMed - indexed for MEDLINE]Related articles

Carbohydrates.

Wahren J, Leverve X.

Curr Opin Clin Nutr Metab Care. 2001 Jul;4(4):253-254. No abstract available. PMID: 11507314 [PubMed - as supplied by publisher]Related articles

Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction.

Katz A, Ekberg K, Johansson BL, Wahren J.

Clin Sci (Lond). 2001 Jul;101(1):59-64.PMID: 11410115 [PubMed - indexed for MEDLINE]Related articles

C-peptide binding to human cell membranes: importance of Glu27.

Pramanik A, Ekberg K, Zhong Z, Shafqat J, Henriksson M, Jansson O, Tibell A, Tally M, Wahren J, Jörnvall H, Rigler R, Johansson J.

Biochem Biophys Res Commun. 2001 Jun 1;284(1):94-8.PMID: 11374876 [PubMed - indexed for MEDLINE]Related articles

Substance P: a pioneer amongst neuropeptides.

Hökfelt T, Pernow B, Wahren J.

J Intern Med. 2001 Jan;249(1):27-40. Review.PMID: 11168782 [PubMed - indexed for MEDLINE]Related articles

Specific binding of proinsulin C-peptide to intact and to detergent-solubilized human skin fibroblasts.

Henriksson M, Pramanik A, Shafqat J, Zhong Z, Tally M, Ekberg K, Wahren J, Rigler R, Johansson J, Jörnvall H.

Biochem Biophys Res Commun. 2001 Jan 19;280(2):423-7.PMID: 11162533 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus.

Johansson BL, Borg K, Fernqvist-Forbes E, Kernell A, Odergren T, Wahren J.

Diabet Med. 2000 Mar;17(3):181-9.PMID: 10784221 [PubMed - indexed for MEDLINE]Related articles

Role of C-peptide in human physiology.

Wahren J, Ekberg K, Johansson J, Henriksson M, Pramanik A, Johansson BL, Rigler R, Jörnvall H.

Am J Physiol Endocrinol Metab. 2000 May;278(5):E759-68. Review.PMID: 10780930 [PubMed - indexed for MEDLINE]Related articlesFree article