PubMed

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia.

Dinour D, Gray NK, Campbell S, Shu X, Sawyer L, Richardson W, Rechavi G, Amariglio N, Ganon L, Sela BA, Bahat H, Goldman M, Weissgarten J, Millar MR, Wright AF, Holtzman EJ.

J Am Soc Nephrol. 2009 Nov 19. [Epub ahead of print]PMID: 19926891 [PubMed - as supplied by publisher]Related articles

Short communication: comparison of visual-tactile, radiographic, and histologic diagnoses of subgingival crown margin caries- an in vitro study.

Wittneben JG, Wright AF, Weber HP.

Int J Prosthodont. 2009 Nov-Dec;22(6):561-5.PMID: 19918589 [PubMed - in process]Related articles

Heritabilities of ocular biometrical traits in 2 Croatian isolates with extended pedigrees.

Vitart V, Bencic G, Hayward C, Herman JS, Huffman JE, Campbell S, Bucan K, Zgaga L, Kolcic I, Polasek O, Campbell H, Wright AF, Vatavuk Z, Rudan I.

Invest Ophthalmol Vis Sci. 2009 Oct 29. [Epub ahead of print]PMID: 19875653 [PubMed - as supplied by publisher]Related articles

Linkage and Genome-wide Association Analysis of Obesity-related Phenotypes: Association of Weight With the MGAT1 Gene.

Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Floyd J, Hastie N, Knott S, Lauc G, Pichler I, Rotim K, Wild SH, Zorkoltseva IV, Wilson JF, Rudan I, Campbell H, Pattaro C, Pramstaller P, Oostra BA, Wright AF, van Duijn CM, Aulchenko YS, Gyllensten U; for the EUROSPAN Consortium.

Obesity (Silver Spring). 2009 Oct 22. [Epub ahead of print]PMID: 19851299 [PubMed - as supplied by publisher]Related articles

Recent insights into the pathogenesis of hyperuricaemia and gout.

Riches PL, Wright AF, Ralston SH.

Hum Mol Genet. 2009 Oct 15;18(R2):R177-84.PMID: 19808794 [PubMed - in process]Related articles

Human population structure, genome autozygosity and human health.

Campbell H, Rudan I, Bittles AH, Wright AF.

Genome Med. 2009 Sep 28;1(9):91.PMID: 19804611 [PubMed - in process]Related articlesFree article

Genetic comparison of a Croatian isolate and CEPH European founders.

Navarro P, Vitart V, Hayward C, Tenesa A, Zgaga L, Juricic D, Polasek O, Hastie ND, Rudan I, Campbell H, Wright AF, Haley CS, Knott SA.

Genet Epidemiol. 2009 Aug 20. [Epub ahead of print]PMID: 19697321 [PubMed - as supplied by publisher]Related articles

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H; EUROSPAN Consortium, Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI; ENGAGE Consortium, Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani NJ, Schlessinger D, Uda M, Völker U, Waeber G, Waterworth D, Wang-Sattler R, Wright AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H; PROCARDIS Consortium, Doering A, Wichmann HE; KORA Study, Spector TD, Peltonen L, Völzke H, Nagaraja R, Vollenweider P, Caulfield M; WTCCC, Illig T, Gieger C.

PLoS Genet. 2009 Jun;5(6):e1000504. Epub 2009 Jun 5.PMID: 19503597 [PubMed - indexed for MEDLINE]Related articlesFree article

Do organellar genomes function as long-term redox damage sensors?

Wright AF, Murphy MP, Turnbull DM.

Trends Genet. 2009 Jun;25(6):253-61. Epub 2009 May 27.PMID: 19481287 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage analysis of serum creatinine in three isolated European populations.

Pattaro C, Aulchenko YS, Isaacs A, Vitart V, Hayward C, Franklin CS, Polasek O, Kolcic I, Biloglav Z, Campbell S, Hastie N, Lauc G, Meitinger T, Oostra BA, Gyllensten U, Wilson JF, Pichler I, Hicks AA, Campbell H, Wright AF, Rudan I, van Duijn CM, Riegler P, Marroni F, Pramstaller PP; EUROSPAN Consortium.

Kidney Int. 2009 Aug;76(3):297-306. Epub 2009 Apr 22.PMID: 19387472 [PubMed - in process]Related articles

A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate.

Barbalić M, Narancić NS, Skarić-Jurić T, Salihović MP, Klarić IM, Lauc LB, Janićijević B, Farrall M, Rudan I, Campbell H, Wright AF, Hastie ND, Rudan P.

Am J Hypertens. 2009 Jun;22(6):663-8. Epub 2009 Mar 5.PMID: 19265782 [PubMed - indexed for MEDLINE]Related articles

Historic, demographic, and genetic evidence for increased population frequencies of CCR5Delta32 mutation in Croatian Island isolates after lethal 15th century epidemics.

Biloglav Z, Zgaga L, Smoljanović M, Hayward C, Polasek O, Kolcić I, Vitart V, Zemunik T, Boraska V, Torlak V, Mulić R, Ropac D, Grković I, Rudan D, Ristić S, Barbalić M, Campbell H, Wright AF, Rudan I.

Croat Med J. 2009 Feb;50(1):34-42.PMID: 19260142 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association study of biochemical traits in Korcula Island, Croatia.

Zemunik T, Boban M, Lauc G, Janković S, Rotim K, Vatavuk Z, Bencić G, Dogas Z, Boraska V, Torlak V, Susac J, Zobić I, Rudan D, Pulanić D, Modun D, Mudnić I, Gunjaca G, Budimir D, Hayward C, Vitart V, Wright AF, Campbell H, Rudan I.

Croat Med J. 2009 Feb;50(1):23-33.PMID: 19260141 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association study of anthropometric traits in Korcula Island, Croatia.

Polasek O, Marusić A, Rotim K, Hayward C, Vitart V, Huffman J, Campbell S, Janković S, Boban M, Biloglav Z, Kolcić I, Krzelj V, Terzić J, Matec L, Tometić G, Nonković D, Nincević J, Pehlić M, Zedelj J, Velagić V, Juricić D, Kirac I, Belak Kovacević S, Wright AF, Campbell H, Rudan I.

Croat Med J. 2009 Feb;50(1):7-16.PMID: 19260139 [PubMed - indexed for MEDLINE]Related articlesFree article

High-throughput glycome analysis is set to join high-throughput genomics.

Rudd PM, Rudan I, Wright AF.

J Proteome Res. 2009 Mar;8(3):1105. No abstract available. PMID: 19193056 [PubMed - indexed for MEDLINE]Related articles

Complement component C3 and risk of age-related macular degeneration.

Despriet DD, van Duijn CM, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PT, Vingerling JR, Bergen AA, Klaver CC.

Ophthalmology. 2009 Mar;116(3):474-480.e2. Epub 2009 Jan 24.PMID: 19168221 [PubMed - indexed for MEDLINE]Related articles

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis.

Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Dunlop MG, Floyd J, Hastie N, Hofman A, Knott S, Kolcic I, Pichler I, Polasek O, Rivadeneira F, Tenesa A, Uitterlinden AG, Wild SH, Zorkoltseva IV, Meitinger T, Wilson JF, Rudan I, Campbell H, Pattaro C, Pramstaller P, Oostra BA, Wright AF, van Duijn CM, Aulchenko YS, Gyllensten U; EUROSPAN Consortium.

Hum Mol Genet. 2009 Jan 15;18(2):373-80. Epub 2008 Oct 24.PMID: 18952825 [PubMed - indexed for MEDLINE]Related articles

Mortality in women with turner syndrome in Great Britain: a national cohort study.

Schoemaker MJ, Swerdlow AJ, Higgins CD, Wright AF, Jacobs PA; United Kingdom Clinical Cytogenetics Group.

J Clin Endocrinol Metab. 2008 Dec;93(12):4735-42. Epub 2008 Sep 23.PMID: 18812477 [PubMed - indexed for MEDLINE]Related articles

Runs of homozygosity in European populations.

McQuillan R, Leutenegger AL, Abdel-Rahman R, Franklin CS, Pericic M, Barac-Lauc L, Smolej-Narancic N, Janicijevic B, Polasek O, Tenesa A, Macleod AK, Farrington SM, Rudan P, Hayward C, Vitart V, Rudan I, Wild SH, Dunlop MG, Wright AF, Campbell H, Wilson JF.

Am J Hum Genet. 2008 Sep;83(3):359-72. Epub 2008 Aug 28. Erratum in: Am J Hum Genet. 2008 Nov;83(5):658. PMID: 18760389 [PubMed - indexed for MEDLINE]Related articlesFree article

Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study.

Swerdlow AJ, Schoemaker MJ, Higgins CD, Wright AF, Jacobs PA.

Br J Cancer. 2008 Jun 17;98(12):1929-33. Epub 2008 May 27.PMID: 18506147 [PubMed - indexed for MEDLINE]Related articlesFree article

The human retinitis pigmentosa GTPase regulator gene variant database.

Shu X, McDowall E, Brown AF, Wright AF.

Hum Mutat. 2008 May;29(5):605-8.PMID: 18361418 [PubMed - indexed for MEDLINE]Related articles

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.

Vitart V, Rudan I, Hayward C, Gray NK, Floyd J, Palmer CN, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Shu X, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Klaric IM, Zgaga L, Skaric-Juric T, Wild SH, Richardson WA, Hohenstein P, Kimber CH, Tenesa A, Donnelly LA, Fairbanks LD, Aringer M, McKeigue PM, Ralston SH, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF.

Nat Genet. 2008 Apr;40(4):437-42. Epub 2008 Mar 9.PMID: 18327257 [PubMed - indexed for MEDLINE]Related articles

Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study.

Schoemaker MJ, Swerdlow AJ, Higgins CD, Wright AF, Jacobs PA; UK Clinical Cytogenetics Group.

Lancet Oncol. 2008 Mar;9(3):239-46. Epub 2008 Feb 20.PMID: 18282803 [PubMed - indexed for MEDLINE]Related articles

Mortality risks in patients with constitutional autosomal chromosome deletions in Britain: a cohort study.

Swerdlow AJ, Schoemaker MJ, Higgins CD, Wright AF, Jacobs PA; UK Clinical Cytogenetics Group.

Hum Genet. 2008 Mar;123(2):215-24. Epub 2008 Jan 15.PMID: 18196273 [PubMed - indexed for MEDLINE]Related articles

Complement C3 variant and the risk of age-related macular degeneration.

Yates JR, Sepp T, Matharu BK, Khan JC, Thurlby DA, Shahid H, Clayton DG, Hayward C, Morgan J, Wright AF, Armbrecht AM, Dhillon B, Deary IJ, Redmond E, Bird AC, Moore AT; Genetic Factors in AMD Study Group.

N Engl J Med. 2007 Aug 9;357(6):553-61. Epub 2007 Jul 18.PMID: 17634448 [PubMed - indexed for MEDLINE]Related articlesFree article

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

Harris SE, Fox H, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ.

BMC Genet. 2007 Jul 2;8:43.PMID: 17601350 [PubMed - indexed for MEDLINE]Related articlesFree article

Mortality and cancer incidence in males with Y polysomy in Britain: a cohort study.

Higgins CD, Swerdlow AJ, Schoemaker MJ, Wright AF, Jacobs PA; UK Clinical Cytogenetics Group.

Hum Genet. 2007 Jul;121(6):691-6. Epub 2007 Apr 25.PMID: 17457613 [PubMed - indexed for MEDLINE]Related articles

Biochemical characterisation of the C1QTNF5 gene associated with late-onset retinal degeneration. A genetic model of age-related macular degeneration.

Shu X, Tulloch B, Lennon A, Hayward C, O'Connell M, Cideciyan AV, Jacobson SG, Wright AF.

Adv Exp Med Biol. 2006;572:41-8. No abstract available. PMID: 17249553 [PubMed - indexed for MEDLINE]Related articles

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits.

Campbell H, Carothers AD, Rudan I, Hayward C, Biloglav Z, Barac L, Pericic M, Janicijevic B, Smolej-Narancic N, Polasek O, Kolcic I, Weber JL, Hastie ND, Rudan P, Wright AF.

Hum Mol Genet. 2007 Jan 15;16(2):233-41. Epub 2007 Jan 12.PMID: 17220173 [PubMed - indexed for MEDLINE]Related articlesFree article

RPGR mutation analysis and disease: an update.

Shu X, Black GC, Rice JM, Hart-Holden N, Jones A, O'Grady A, Ramsden S, Wright AF.

Hum Mutat. 2007 Apr;28(4):322-8.PMID: 17195164 [PubMed - indexed for MEDLINE]Related articles

Contribution of consanguinuity to polygenic and multifactorial diseases.

Rudan I, Campbell H, Carothers AD, Hastie ND, Wright AF.

Nat Genet. 2006 Nov;38(11):1224-5. No abstract available. PMID: 17072294 [PubMed - indexed for MEDLINE]Related articles

Molecular genetics of retinitis pigmentosa in two Romani (Gypsy) families.

Chakarova CF, Cherninkova S, Tournev I, Waseem N, Kaneva R, Jordanova A, Veraitch BK, Gill B, Colclough T, Nakova A, Oscar A, Mihaylova V, Nikolova-Hill A, Wright AF, Black GC, Ramsden S, Kremensky I, Bhattacharya SS.

Mol Vis. 2006 Aug 11;12:909-14.PMID: 16917484 [PubMed - indexed for MEDLINE]Related articlesFree article

Strategy for mapping quantitative trait loci (QTL) by using human metapopulations.

Rudan I, Biloglav Z, Carothers AD, Wright AF, Campbell H.

Croat Med J. 2006 Aug;47(4):532-42.PMID: 16909450 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches.

Carothers AD, Rudan I, Kolcic I, Polasek O, Hayward C, Wright AF, Campbell H, Teague P, Hastie ND, Weber JL.

Ann Hum Genet. 2006 Sep;70(Pt 5):666-76.PMID: 16907711 [PubMed - indexed for MEDLINE]Related articles

Focus on Molecules: RPGR.

Wright AF, Shu X.

Exp Eye Res. 2007 Jul;85(1):1-2. Epub 2006 Jun 12. Review. No abstract available. PMID: 16769054 [PubMed - indexed for MEDLINE]Related articles

Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5.

Shu X, Tulloch B, Lennon A, Vlachantoni D, Zhou X, Hayward C, Wright AF.

Hum Mol Genet. 2006 May 15;15(10):1680-9. Epub 2006 Apr 6.PMID: 16600989 [PubMed - indexed for MEDLINE]Related articlesFree article

The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills.

Harris SE, Fox H, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ.

Mol Psychiatry. 2006 May;11(5):505-13.PMID: 16446742 [PubMed - indexed for MEDLINE]Related articles

A microdeletion in Xp11.3 accounts for co-segregation of retinitis pigmentosa and mental retardation in a large kindred.

Zhang L, Wang T, Wright AF, Suri M, Schwartz CE, Stevenson RE, Valle D.

Am J Med Genet A. 2006 Feb 15;140(4):349-57.PMID: 16419135 [PubMed - indexed for MEDLINE]Related articles

Developmental and tissue expression of Xenopus laevis RPGR.

Shu X, Zeng Z, Eckmiller MS, Gautier P, Vlachantoni D, Manson FD, Tulloch B, Sharpe C, Gorecki DC, Wright AF.

Invest Ophthalmol Vis Sci. 2006 Jan;47(1):348-56.PMID: 16384984 [PubMed - indexed for MEDLINE]Related articlesFree article

Long anterior lens zonules in late-onset retinal degeneration (L-ORD).

Subrayan V, Morris B, Armbrecht AM, Wright AF, Dhillon B.

Am J Ophthalmol. 2005 Dec;140(6):1127-9.PMID: 16376663 [PubMed - indexed for MEDLINE]Related articles

Mortality in patients with Klinefelter syndrome in Britain: a cohort study.

Swerdlow AJ, Higgins CD, Schoemaker MJ, Wright AF, Jacobs PA; United Kingdom Clinical Cytogenetics Group.

J Clin Endocrinol Metab. 2005 Dec;90(12):6516-22. Epub 2005 Oct 4.PMID: 16204366 [PubMed - indexed for MEDLINE]Related articlesFree article

Mortality and cancer incidence in women with extra X chromosomes: a cohort study in Britain.

Swerdlow AJ, Schoemaker MJ, Higgins CD, Wright AF, Jacobs PA.

Hum Genet. 2005 Nov;118(2):255-60. Epub 2005 Nov 15.PMID: 16151857 [PubMed - indexed for MEDLINE]Related articles

Cancer incidence and mortality in men with Klinefelter syndrome: a cohort study.

Swerdlow AJ, Schoemaker MJ, Higgins CD, Wright AF, Jacobs PA; UK Clinical Cytogenetics Group.

J Natl Cancer Inst. 2005 Aug 17;97(16):1204-10.PMID: 16106025 [PubMed - indexed for MEDLINE]Related articlesFree article

RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins.

Khanna H, Hurd TW, Lillo C, Shu X, Parapuram SK, He S, Akimoto M, Wright AF, Margolis B, Williams DS, Swaroop A.

J Biol Chem. 2005 Sep 30;280(39):33580-7. Epub 2005 Jul 25.PMID: 16043481 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic influences on oxidative stress and their association with normal cognitive ageing.

Kachiwala SJ, Harris SE, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ.

Neurosci Lett. 2005 Sep 30;386(2):116-20.PMID: 16023289 [PubMed - indexed for MEDLINE]Related articles

The functional COMT polymorphism, Val 158 Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year olds.

Harris SE, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ.

Neurosci Lett. 2005 Sep 2;385(1):1-6.PMID: 15979789 [PubMed - indexed for MEDLINE]Related articles

Neurogenetics II: complex disorders.

Wright AF.

J Neurol Neurosurg Psychiatry. 2005 May;76(5):623-31. Review.PMID: 15834017 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased level of linkage disequilibrium in rural compared with urban communities: a factor to consider in association-study design.

Vitart V, Carothers AD, Hayward C, Teague P, Hastie ND, Campbell H, Wright AF.

Am J Hum Genet. 2005 May;76(5):763-72. Epub 2005 Mar 24.PMID: 15791542 [PubMed - indexed for MEDLINE]Related articlesFree article

RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin.

Shu X, Fry AM, Tulloch B, Manson FD, Crabb JW, Khanna H, Faragher AJ, Lennon A, He S, Trojan P, Giessl A, Wolfrum U, Vervoort R, Swaroop A, Wright AF.

Hum Mol Genet. 2005 May 1;14(9):1183-97. Epub 2005 Mar 16.PMID: 15772089 [PubMed - indexed for MEDLINE]Related articlesFree article

KLOTHO genotype and cognitive ability in childhood and old age in the same individuals.

Deary IJ, Harris SE, Fox HC, Hayward C, Wright AF, Starr JM, Whalley LJ.

Neurosci Lett. 2005 Apr 11;378(1):22-7. Epub 2005 Jan 22.PMID: 15763166 [PubMed - indexed for MEDLINE]Related articles