PubMed

A method for detecting and preventing negative RNA interference in preparation of lentiviral vectors for siRNA delivery.

Zhou D, Zhang J, Wang C, Bliesath JR, He Q, Yu D, Li-He Z, Wong-Staal F.

RNA. 2009 Apr;15(4):732-40. Epub 2009 Feb 25.PMID: 19244361 [PubMed - indexed for MEDLINE]Related articlesFree article

Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy.

Yu DH, Macdonald J, Liu G, Lee AS, Ly M, Davis T, Ke N, Zhou D, Wong-Staal F, Li QX.

PLoS One. 2008;3(12):e3951. Epub 2008 Dec 16.PMID: 19079611 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening of small-molecule compounds as inhibitors of HCV entry.

Yang JP, Zhou D, Wong-Staal F.

Methods Mol Biol. 2009;510:295-304.PMID: 19009270 [PubMed - indexed for MEDLINE]Related articles

Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication.

He QS, Tang H, Zhang J, Truong K, Wong-Staal F, Zhou D.

J Virol Methods. 2008 Dec;154(1-2):216-9. Epub 2008 Sep 30.PMID: 18782589 [PubMed - indexed for MEDLINE]Related articles

Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186.

Falkenstein IA, Cheng L, Wong-Staal F, Tammewar AM, Barron EC, Silva GA, Li QX, Yu D, Hysell M, Liu G, Ke N, Macdonald JE, Freeman WR.

Curr Eye Res. 2008 Jul;33(7):599-609.PMID: 18600493 [PubMed - indexed for MEDLINE]Related articlesFree article

Oncolytic virotherapy as a personalized cancer vaccine.

Li QX, Liu G, Wong-Staal F.

Int J Cancer. 2008 Aug 1;123(3):493-9. Review.PMID: 18500742 [PubMed - indexed for MEDLINE]Related articles

Selective anticancer strategies via intervention of the death pathways relevant to cell transformation.

Li QX, Yu DH, Liu G, Ke N, McKelvy J, Wong-Staal F.

Cell Death Differ. 2008 Aug;15(8):1197-210. Epub 2008 Apr 25. Review.PMID: 18437165 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of shRNA pool library: a revision of the biological technique from the viewpoint of chemistry.

Zhou D, Wang C, Zhang J, Bliesath J, He QS, Ke N, Yu D, Li Q, Zhang LH, Wong-Staal F.

Chembiochem. 2008 Jun 16;9(9):1365-7. No abstract available. PMID: 18435449 [PubMed - indexed for MEDLINE]Related articles

Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP).

Ke N, Ma H, Diedrich G, Chionis J, Liu G, Yu DH, Wong-Staal F, Li QX.

Biochem Biophys Res Commun. 2008 Feb 8;366(2):314-20. Epub 2007 Nov 26.PMID: 18042463 [PubMed - indexed for MEDLINE]Related articles

Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase.

Liu G, Grifman M, Macdonald J, Moller P, Wong-Staal F, Li QX.

J Endocrinol. 2007 Sep;194(3):569-78.PMID: 17761896 [PubMed - indexed for MEDLINE]Related articlesFree article

A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals.

Zhang J, Wang C, Ke N, Bliesath J, Chionis J, He QS, Li QX, Chatterton JE, Wong-Staal F, Zhou D.

RNA. 2007 Aug;13(8):1375-83. Epub 2007 Jul 6.PMID: 17616554 [PubMed - indexed for MEDLINE]Related articlesFree article

Orphan G protein-coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway.

Ke N, Sundaram R, Liu G, Chionis J, Fan W, Rogers C, Awad T, Grifman M, Yu D, Wong-Staal F, Li QX.

Mol Cancer Ther. 2007 Jun;6(6):1840-50.PMID: 17575113 [PubMed - indexed for MEDLINE]Related articlesFree article

Ribozyme technology for cancer gene target identification and validation.

Li QX, Tan P, Ke N, Wong-Staal F.

Adv Cancer Res. 2007;96:103-43. Review.PMID: 17161678 [PubMed - indexed for MEDLINE]Related articles

Development of new RNAi therapeutics.

Liu G, Wong-Staal F, Li QX.

Histol Histopathol. 2007 Feb;22(2):211-7. Review.PMID: 17149694 [PubMed - indexed for MEDLINE]Related articles

RNA interference and potential applications.

Zhou D, He QS, Wang C, Zhang J, Wong-Staal F.

Curr Top Med Chem. 2006;6(9):901-11. Review.PMID: 16787283 [PubMed - indexed for MEDLINE]Related articles

A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing.

Ke N, Zhou D, Chatterton JE, Liu G, Chionis J, Zhang J, Tsugawa L, Lynn R, Yu D, Meyhack B, Wong-Staal F, Li QX.

Exp Cell Res. 2006 Sep 10;312(15):2726-34.PMID: 16765945 [PubMed - indexed for MEDLINE]Related articles

MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53.

Yu DH, Macdonald J, Josephs S, Liu Q, Nguy V, Tor Y, Wong-Staal F, Li QX.

Invest New Drugs. 2006 Nov;24(6):489-98.PMID: 16633716 [PubMed - indexed for MEDLINE]Related articles

A novel RNAi library based on partially randomized consensus sequences of nuclear receptors: identifying the receptors involved in amyloid beta degradation.

Yang JP, Fan W, Rogers C, Chatterton JE, Bliesath J, Liu G, Ke N, Wang CY, Rhoades K, Wong-Staal F, Li QX.

Genomics. 2006 Sep;88(3):282-92. Epub 2006 May 2.PMID: 16631344 [PubMed - indexed for MEDLINE]Related articles

Therapy with ribozyme to the proliferating cell nuclear antigen-ribozyme and 5-fluorouracil of experimental choroidal neovascularization in rats.

Kayikcioglu OR, Falkenstein I, Cheng L, Kozak I, La Bree L, Azen SP, Wong-Staal F, Paoni NF, Freeman WR.

J Ocul Pharmacol Ther. 2006 Feb;22(1):1-9.PMID: 16503769 [PubMed - indexed for MEDLINE]Related articles

NR4A1, 2, 3--an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis.

Li QX, Ke N, Sundaram R, Wong-Staal F.

Histol Histopathol. 2006 May;21(5):533-40. Review.PMID: 16493583 [PubMed - indexed for MEDLINE]Related articles

PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway.

Yu DH, Fan W, Liu G, Nguy V, Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX.

Exp Cell Res. 2006 Apr 1;312(6):865-76. Epub 2006 Jan 17.PMID: 16413018 [PubMed - indexed for MEDLINE]Related articles

Expression, purification, and renaturation of bone morphogenetic protein-2 from Escherichia coli.

Long S, Truong L, Bennett K, Phillips A, Wong-Staal F, Ma H.

Protein Expr Purif. 2006 Apr;46(2):374-8. Epub 2005 Oct 27.PMID: 16298141 [PubMed - indexed for MEDLINE]Related articles

A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets.

Yu DH, Chatterton JE, Bliesath JR, Sundaram R, Ke N, Nguy V, Meyhack B, Wong-Staal F, Li QX.

Assay Drug Dev Technol. 2005 Aug;3(4):401-11.PMID: 16180995 [PubMed - indexed for MEDLINE]Related articles

The development and applications of nonradioactive plate-formatted DNA-binding assay for Ku70/80, a multifunctional DNA-binding protein complex.

Ma H, Thibault J, Lu Y, Whiting C, Long S, Lindwall G, Bennett K, Truong L, Aimes RT, Wong-Staal F.

Assay Drug Dev Technol. 2004 Oct;2(5):483-95.PMID: 15671646 [PubMed - indexed for MEDLINE]Related articles

Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis.

Ke N, Claassen G, Yu DH, Albers A, Fan W, Tan P, Grifman M, Hu X, Defife K, Nguy V, Meyhack B, Brachat A, Wong-Staal F, Li QX.

Cancer Res. 2004 Nov 15;64(22):8208-12.PMID: 15548686 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach.

Waninger S, Kuhen K, Hu X, Chatterton JE, Wong-Staal F, Tang H.

J Virol. 2004 Dec;78(23):12829-37.PMID: 15542635 [PubMed - indexed for MEDLINE]Related articlesFree article

RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.

Tetsuka T, Uranishi H, Sanda T, Asamitsu K, Yang JP, Wong-Staal F, Okamoto T.

Eur J Biochem. 2004 Sep;271(18):3741-51.PMID: 15355351 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus.

Hu X, Hipolito S, Lynn R, Abraham V, Ramos S, Wong-Staal F.

Nucleic Acids Res. 2004 Aug 27;32(15):4609-17. Print 2004.PMID: 15333693 [PubMed - indexed for MEDLINE]Related articlesFree article

Transduction of cell lines and primary cells by FIV-packaged HIV vectors.

Morris KV, Gilbert J, Wong-Staal F, Gasmi M, Looney DJ.

Mol Ther. 2004 Jul;10(1):181-90.PMID: 15272479 [PubMed - indexed for MEDLINE]Related articles

One-week 96-well soft agar growth assay for cancer target validation.

Ke N, Albers A, Claassen G, Yu DH, Chatterton JE, Hu X, Meyhack B, Wong-Staal F, Li QX.

Biotechniques. 2004 May;36(5):826-8, 830, 832-3.PMID: 15152603 [PubMed - indexed for MEDLINE]Related articles

The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope.

Kan-Mitchell J, Bisikirska B, Wong-Staal F, Schaubert KL, Bajcz M, Bereta M.

J Immunol. 2004 May 1;172(9):5249-61.PMID: 15100263 [PubMed - indexed for MEDLINE]Related articlesFree article

Arginine methylation of RNA helicase a determines its subcellular localization.

Smith WA, Schurter BT, Wong-Staal F, David M.

J Biol Chem. 2004 May 28;279(22):22795-8. Epub 2004 Apr 14.PMID: 15084609 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation of dendritic cells from lentiviral vector-transduced CD34+ cells from HIV+ donors.

Gruber A, Chen I, Kuhen KL, Wheat JC, Law P, Wong-Staal F.

J Med Virol. 2003 Jun;70(2):183-6.PMID: 12696103 [PubMed - indexed for MEDLINE]Related articles

Integrated approaches to therapeutic target gene discovery.

DeFife KM, Wong-Staal F.

Curr Opin Drug Discov Devel. 2002 Sep;5(5):683-9. Review.PMID: 12630288 [PubMed - indexed for MEDLINE]Related articles

Inverse Genomics as a powerful tool to identify novel targets for the treatment of neurodegenerative diseases.

Rhoades K, Wong-Staal F.

Mech Ageing Dev. 2003 Jan;124(1):125-32.PMID: 12618015 [PubMed - indexed for MEDLINE]Related articles

HIV-2 and SIV vector systems.

Gilbert JR, Wong-Staal F.

Somat Cell Mol Genet. 2001 Nov;26(1-6):83-98. Review.PMID: 12465463 [PubMed - indexed for MEDLINE]Related articles

Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K.

Yang JP, Reddy TR, Truong KT, Suhasini M, Wong-Staal F.

Oncogene. 2002 Oct 17;21(47):7187-94.PMID: 12370808 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV.

Tang H, Peng T, Wong-Staal F.

Curr Opin Pharmacol. 2002 Oct;2(5):541-7. Review.PMID: 12324256 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 2 (HIV-2) vector-mediated in vivo gene transfer into adult rabbit retina.

Cheng L, Chaidhawangul S, Wong-Staal F, Gilbert J, Poeschla E, Toyoguchi M, El-Bradey M, Bergeron-Lynn G, Soules KA, Freeman WR.

Curr Eye Res. 2002 Mar;24(3):196-201.PMID: 12221527 [PubMed - indexed for MEDLINE]Related articles

One-step, highly efficient site-directed mutagenesis by toxic protein selection.

Xu W, Zhang Y, Yeh LY, Ruprecht CR, Wong-Staal F, McFadden BA, Reddy TR, Ruprecht RM.

Biotechniques. 2002 Jun;32(6):1266-8, 1270.PMID: 12074156 [PubMed - indexed for MEDLINE]Related articles

Recognition of engineered tRNAs with an extended 3' end by Exportin-t (Xpo-t) and transport of tRNA-attached ribozymes to the cytoplasm in somatic cells.

Kuwabara T, Warashina M, Sano M, Tang H, Wong-Staal F, Munekata E, Taira K.

Biomacromolecules. 2001 Winter;2(4):1229-42.PMID: 11777397 [PubMed - indexed for MEDLINE]Related articles

A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication.

Reddy TR, Suhasini M, Xu W, Yeh LY, Yang JP, Wu J, Artzt K, Wong-Staal F.

J Biol Chem. 2002 Feb 22;277(8):5778-84. Epub 2001 Dec 7.PMID: 11741900 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation.

Krüger M, Beger C, Welch PJ, Barber JR, Manns MP, Wong-Staal F.

Mol Cell Biol. 2001 Dec;21(24):8357-64.PMID: 11713272 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells.

Cortés MJ, Wong-Staal F, Lama J.

J Biol Chem. 2002 Jan 18;277(3):1770-9. Epub 2001 Nov 9.PMID: 11704677 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of HIV-1 protease inhibitors on dendritic cell immunophenotype and function.

Gruber A, Wheat JC, Kuhen KL, Looney DJ, Wong-Staal F.

J Biol Chem. 2001 Dec 21;276(51):47840-3. Epub 2001 Oct 15.PMID: 11602580 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered immunophenotype of dendritic cells generated from HIV infected subjects.

Gruber A, Looney DJ, Ibanez M, Wong-Staal F.

Immunol Lett. 2001 Oct 1;78(3):209-11. No abstract available. PMID: 11578697 [PubMed - indexed for MEDLINE]Related articles

C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification.

Krüger M, Beger C, Welch PJ, Barber JR, Wong-Staal F.

Nucleic Acids Res. 2001 Oct 1;29(19):E94.PMID: 11574696 [PubMed - indexed for MEDLINE]Related articlesFree article

Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses.

Yang JP, Tang H, Reddy TR, Wong-Staal F.

J Biol Chem. 2001 Aug 17;276(33):30694-700. Epub 2001 Jun 11.PMID: 11402034 [PubMed - indexed for MEDLINE]Related articlesFree article

Approaches to gene therapy for human immunodeficiency virus infection.

Buchschacher GL Jr, Wong-Staal F.

Hum Gene Ther. 2001 Jun 10;12(9):1013-9. Review.PMID: 11399224 [PubMed - indexed for MEDLINE]Related articles

Development of lentiviral vectors for gene therapy for human diseases.

Buchschacher GL Jr, Wong-Staal F.

Blood. 2000 Apr 15;95(8):2499-504. Review.PMID: 10753827 [PubMed - indexed for MEDLINE]Related articlesFree article