PubMed

[In Process Citation]

Walker LC.

Soins. 2009 Oct;(739):50-3. French. No abstract available. PMID: 19928680 [PubMed - in process]

The Grandmother Effect and the Uniqueness of the Human Aging Phenotype: A Debate.

Herndon JG, Walker LC.

Gerontology. 2009 Oct 28. [Epub ahead of print]PMID: 19864883 [PubMed - as supplied by publisher]Related articles

Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease.

Rosen RF, Ciliax BJ, Wingo TS, Gearing M, Dooyema J, Lah JJ, Ghiso JA, Levine H 3rd, Walker LC.

Acta Neuropathol. 2009 Aug 19. [Epub ahead of print]PMID: 19690877 [PubMed - as supplied by publisher]Related articles

Ovarian aging in squirrel monkeys (Saimiri sciureus).

Walker ML, Anderson DC, Herndon JG, Walker LC.

Reproduction. 2009 Nov;138(5):793-9. Epub 2009 Aug 5.PMID: 19656956 [PubMed - in process]Related articles

Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation.

Eisele YS, Bolmont T, Heikenwalder M, Langer F, Jacobson LH, Yan ZX, Roth K, Aguzzi A, Staufenbiel M, Walker LC, Jucker M.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12926-31. Epub 2009 Jul 21.PMID: 19622727 [PubMed - indexed for MEDLINE]Related articles

Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression?

Pahnke J, Walker LC, Scheffler K, Krohn M.

Neurosci Biobehav Rev. 2009 Jul;33(7):1099-108. Epub 2009 May 27. Review.PMID: 19481107 [PubMed - indexed for MEDLINE]Related articles

PIB binding in aged primate brain: Enrichment of high-affinity sites in humans with Alzheimer's disease.

Rosen RF, Walker LC, Levine H 3rd.

Neurobiol Aging. 2009 Mar 27. [Epub ahead of print]PMID: 19329226 [PubMed - as supplied by publisher]Related articles

The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors.

Simons LJ, Caprathe BW, Callahan M, Graham JM, Kimura T, Lai Y, LeVine H 3rd, Lipinski W, Sakkab AT, Tasaki Y, Walker LC, Yasunaga T, Ye Y, Zhuang N, Augelli-Szafran CE.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):654-7. Epub 2008 Dec 24.PMID: 19121939 [PubMed - in process]Related articles

TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2.

Yeowell HN, Walker LC, Mauger DM, Seth P, Garcia-Blanco MA.

J Invest Dermatol. 2009 Jun;129(6):1402-11. Epub 2008 Dec 25.PMID: 19110540 [PubMed - indexed for MEDLINE]Related articles

Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease.

Pahnke J, Wolkenhauer O, Krohn M, Walker LC.

Curr Alzheimer Res. 2008 Aug;5(4):396-405. Review.PMID: 18690837 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular polymorphism of Abeta in Alzheimer's disease.

Levine H 3rd, Walker LC.

Neurobiol Aging. 2008 Jul 9. [Epub ahead of print]PMID: 18619711 [PubMed - as supplied by publisher]Related articles

BRCA1 and BRCA2 missense variants of high and low clinical significance influence lymphoblastoid cell line post-irradiation gene expression.

Waddell N, Ten Haaf A, Marsh A, Johnson J, Walker LC, Investigators K, Gongora M, Brown M, Grover P, Girolami M, Grimmond S, Chenevix-Trench G, Spurdle AB.

PLoS Genet. 2008 May 23;4(5):e1000080.PMID: 18497862 [PubMed - indexed for MEDLINE]Related articlesFree article

Tauopathy with paired helical filaments in an aged chimpanzee.

Rosen RF, Farberg AS, Gearing M, Dooyema J, Long PM, Anderson DC, Davis-Turak J, Coppola G, Geschwind DH, Paré JF, Duong TQ, Hopkins WD, Preuss TM, Walker LC.

J Comp Neurol. 2008 Jul 20;509(3):259-70.PMID: 18481275 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term hypothermia reduces infarct volume in aged rats after focal ischemia.

Florian B, Vintilescu R, Balseanu AT, Buga AM, Grisk O, Walker LC, Kessler C, Popa-Wagner A.

Neurosci Lett. 2008 Jun 20;438(2):180-5. Epub 2008 Apr 10.PMID: 18456407 [PubMed - indexed for MEDLINE]Related articles

Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically.

Agca C, Fritz JJ, Walker LC, Levey AI, Chan AW, Lah JJ, Agca Y.

BMC Neurosci. 2008 Feb 26;9:28.PMID: 18302776 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of chromosome band 8q22 copy number gain with high grade invasive breast carcinomas by assessment of core needle biopsies.

Walker LC, Harris GC, Wells JE, Robinson BA, Morris CM.

Genes Chromosomes Cancer. 2008 May;47(5):405-17.PMID: 18273837 [PubMed - indexed for MEDLINE]Related articles

Diversity of Abeta deposits in the aged brain: a window on molecular heterogeneity?

Walker LC, Rosen RF, Levine H 3rd.

Rom J Morphol Embryol. 2008;49(1):5-11. Review.PMID: 18273496 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.

Walker LC, Waddell N, Ten Haaf A; kConFab Investigators, Grimmond S, Spurdle AB.

Breast Cancer Res Treat. 2008 Nov;112(2):229-36. Epub 2007 Dec 20.PMID: 18095154 [PubMed - indexed for MEDLINE]Related articles

Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast.

Walker LC, Harris GC, Holloway AJ, McKenzie GW, Wells JE, Robinson BA, Morris CM.

Cancer Genet Cytogenet. 2007 Oct 15;178(2):94-103.PMID: 17954264 [PubMed - indexed for MEDLINE]Related articles

The response of the aged brain to stroke: too much, too soon?

Popa-Wagner A, Carmichael ST, Kokaia Z, Kessler C, Walker LC.

Curr Neurovasc Res. 2007 Aug;4(3):216-27. Review.PMID: 17691975 [PubMed - indexed for MEDLINE]Related articles

MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.

Kuhnke D, Jedlitschky G, Grube M, Krohn M, Jucker M, Mosyagin I, Cascorbi I, Walker LC, Kroemer HK, Warzok RW, Vogelgesang S.

Brain Pathol. 2007 Oct;17(4):347-53. Epub 2007 Jul 4.PMID: 17610523 [PubMed - indexed for MEDLINE]Related articles

Depletion of ovarian follicles with age in chimpanzees: similarities to humans.

Jones KP, Walker LC, Anderson D, Lacreuse A, Robson SL, Hawkes K.

Biol Reprod. 2007 Aug;77(2):247-51. Epub 2007 Apr 11.PMID: 17429014 [PubMed - indexed for MEDLINE]Related articlesFree article

Cerebral beta-amyloid angiopathy in aged squirrel monkeys.

Elfenbein HA, Rosen RF, Stephens SL, Switzer RC, Smith Y, Pare J, Mehta PD, Warzok R, Walker LC.

Histol Histopathol. 2007 Feb;22(2):155-67.PMID: 17149688 [PubMed - indexed for MEDLINE]Related articles

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.

Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M.

Science. 2006 Sep 22;313(5794):1781-4.PMID: 16990547 [PubMed - indexed for MEDLINE]Related articlesFree article

Inducible proteopathies.

Walker LC, Levine H 3rd, Mattson MP, Jucker M.

Trends Neurosci. 2006 Aug;29(8):438-43. Epub 2006 Jun 27. Review.PMID: 16806508 [PubMed - indexed for MEDLINE]Related articles

Alzheimer therapeutics-what after the cholinesterase inhibitors?

Walker LC, Rosen RF.

Age Ageing. 2006 Jul;35(4):332-5. Epub 2006 Apr 27. Review. No abstract available. PMID: 16644763 [PubMed - indexed for MEDLINE]Related articlesFree article

Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease.

Vogelgesang S, Glatzel M, Walker LC, Kroemer HK, Aguzzi A, Warzok RW.

Acta Neuropathol. 2006 May;111(5):436-43. Epub 2006 Mar 7.PMID: 16523342 [PubMed - indexed for MEDLINE]Related articles

Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.

Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC.

Brain Res. 2006 Feb 23;1075(1):68-80. Epub 2006 Feb 3.PMID: 16460711 [PubMed - indexed for MEDLINE]Related articles

An Ehlers-Danlos syndrome type VIA patient with cystic malformations of the meninges.

Yeowell HN, Walker LC, Neumann LM.

Eur J Dermatol. 2005 Sep-Oct;15(5):353-8.PMID: 16172044 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.

Vogelgesang S, Warzok RW, Cascorbi I, Kunert-Keil C, Schroeder E, Kroemer HK, Siegmund W, Walker LC, Pahnke J.

Curr Alzheimer Res. 2004 May;1(2):121-5.PMID: 15975076 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel mutation in the lysyl hydroxylase 1 gene causes decreased lysyl hydroxylase activity in an Ehlers-Danlos VIA patient.

Walker LC, Overstreet MA, Siddiqui A, De Paepe A, Ceylaner G, Malfait F, Symoens S, Atsawasuwan P, Yamauchi M, Ceylaner S, Bank RA, Yeowell HN.

J Invest Dermatol. 2005 May;124(5):914-8.PMID: 15854030 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging prospects for the disease-modifying treatment of Alzheimer's disease.

Walker LC, Ibegbu CC, Todd CW, Robinson HL, Jucker M, LeVine H 3rd, Gandy S.

Biochem Pharmacol. 2005 Apr 1;69(7):1001-8. Review.PMID: 15763538 [PubMed - indexed for MEDLINE]Related articles

Proteomic identification of the involvement of the mitochondrial rieske protein in epilepsy.

Junker H, Späte K, Suofu Y, Walther R, Schwarz G, Kammer W, Nordheim A, Walker LC, Runge U, Kessler C, Popa-Wagner A.

Epilepsia. 2005 Mar;46(3):339-43.PMID: 15730530 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific expression and regulation of the alternatively-spliced forms of lysyl hydroxylase 2 (LH2) in human kidney cells and skin fibroblasts.

Walker LC, Overstreet MA, Yeowell HN.

Matrix Biol. 2005 Jan;23(8):515-23. Epub 2004 Dec 10.PMID: 15694128 [PubMed - indexed for MEDLINE]Related articles

Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene.

Walker LC, Teebi AS, Marini JC, De Paepe A, Malfait F, Atsawasuwan P, Yamauchi M, Yeowell HN.

Mol Genet Metab. 2004 Dec;83(4):312-21.PMID: 15589118 [PubMed - indexed for MEDLINE]Related articles

Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy.

Vogelgesang S, Kunert-Keil C, Cascorbi I, Mosyagin I, Schröder E, Runge U, Jedlitschky G, Kroemer HK, Oertel J, Gaab MR, Pahnke J, Walker LC, Warzok RW.

Clin Neuropathol. 2004 Sep-Oct;23(5):223-31.PMID: 15581025 [PubMed - indexed for MEDLINE]Related articles

Heterogeneous basis of the type VIB form of Ehlers-Danlos syndrome (EDS VIB) that is unrelated to decreased collagen lysyl hydroxylation.

Walker LC, Overstreet MA, Willing MC, Marini JC, Cabral WA, Pals G, Bristow J, Atsawasuwan P, Yamauchi M, Yeowell HN.

Am J Med Genet A. 2004 Dec 1;131(2):155-62.PMID: 15523625 [PubMed - indexed for MEDLINE]Related articles

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.

Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S.

J Neurochem. 2004 Aug;90(4):1011-8.PMID: 15287908 [PubMed - indexed for MEDLINE]Related articles

Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta).

Gandy S, DeMattos RB, Lemere CA, Heppner FL, Leverone J, Aguzzi A, Ershler WB, Dai J, Fraser P, Hyslop PS, Holtzman DM, Walker LC, Keller ET.

Alzheimer Dis Assoc Disord. 2004 Jan-Mar;18(1):44-6.PMID: 15195463 [PubMed - indexed for MEDLINE]Related articles

Familial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid leukemia.

Ganly P, Walker LC, Morris CM.

Leuk Lymphoma. 2004 Jan;45(1):1-10. Review.PMID: 15061191 [PubMed - indexed for MEDLINE]Related articles

Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta).

Gandy S, DeMattos RB, Lemere CA, Heppner FL, Leverone J, Aguzzi A, Ershler WB, Dai J, Fraser P, St George Hyslop P, Holtzman DM, Walker LC, Keller ET.

Mech Ageing Dev. 2004 Feb;125(2):149-51.PMID: 15037022 [PubMed - indexed for MEDLINE]Related articles

Postoperative ultrasound-guided percutaneous placement of a new breast brachytherapy balloon catheter.

Zannis VJ, Walker LC, Barclay-White B, Quiet CA.

Am J Surg. 2003 Oct;186(4):383-5.PMID: 14553855 [PubMed - indexed for MEDLINE]Related articles

Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery.

Badan I, Buchhold B, Hamm A, Gratz M, Walker LC, Platt D, Kessler Ch, Popa-Wagner A.

J Cereb Blood Flow Metab. 2003 Jul;23(7):845-54.PMID: 12843788 [PubMed - indexed for MEDLINE]Related articles

Cerebral beta-amyloid deposition is augmented by the -491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E epsilon4 allele.

Pahnke J, Walker LC, Schroeder E, Vogelgesang S, Stausske D, Walther R, Warzok RW.

Acta Neuropathol. 2003 Jan;105(1):25-9. Epub 2002 Nov 5.PMID: 12471457 [PubMed - indexed for MEDLINE]Related articles

Xanthomatosis.

Lipinski WJ, Walker LC, Bian F.

J Neurosurg. 2002 Oct;97(4):1002-4; author reply 1004. No abstract available. PMID: 12405396 [PubMed - indexed for MEDLINE]Related articles

Modeling Alzheimer's disease and other proteopathies in vivo: is seeding the key?

Walker LC, Bian F, Callahan MJ, Lipinski WJ, Durham RA, LeVine H.

Amino Acids. 2002;23(1-3):87-93.PMID: 12373522 [PubMed - indexed for MEDLINE]Related articles

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.

Vogelgesang S, Cascorbi I, Schroeder E, Pahnke J, Kroemer HK, Siegmund W, Kunert-Keil C, Walker LC, Warzok RW.

Pharmacogenetics. 2002 Oct;12(7):535-41.PMID: 12360104 [PubMed - indexed for MEDLINE]Related articles

Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice.

Walker LC, Callahan MJ, Bian F, Durham RA, Roher AE, Lipinski WJ.

Peptides. 2002 Jul;23(7):1241-7.PMID: 12128081 [PubMed - indexed for MEDLINE]Related articles

Proteopathy: the next therapeutic frontier?

Walker LC, LeVine H 3rd.

Curr Opin Investig Drugs. 2002 May;3(5):782-7. Review.PMID: 12090553 [PubMed - indexed for MEDLINE]Related articles

A novel inherited mutation of the transcription factor RUNX1 causes thrombocytopenia and may predispose to acute myeloid leukaemia.

Walker LC, Stevens J, Campbell H, Corbett R, Spearing R, Heaton D, Macdonald DH, Morris CM, Ganly P.

Br J Haematol. 2002 Jun;117(4):878-81.PMID: 12060124 [PubMed - indexed for MEDLINE]Related articles