PubMed

Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats.

Chen Y, Hanaoka M, Droma Y, Chen P, Voelkel NF, Kubo K.

Eur Respir J. 2009 Nov 6. [Epub ahead of print]PMID: 19897563 [PubMed - as supplied by publisher]Related articles

Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.

Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF.

Circulation. 2009 Nov 17;120(20):1951-60. Epub 2009 Nov 2.PMID: 19884466 [PubMed - in process]Related articles

Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation.

Sakao S, Tatsumi K, Voelkel NF.

Respir Res. 2009 Oct 13;10:95.PMID: 19825167 [PubMed - in process]Related articlesFree article

Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension.

Sweeney L, Voelkel NF.

Eur J Med Res. 2009 Sep 28;14(10):433-42.PMID: 19748850 [PubMed - indexed for MEDLINE]Related articles

The relationship between adipokines, body composition, and bone density in men with chronic obstructive pulmonary disease.

Vondracek SF, Voelkel NF, McDermott MT, Valdez C.

Int J Chron Obstruct Pulmon Dis. 2009;4(2):267-77. Epub 2009 Jul 20.PMID: 19657401 [PubMed - in process]Related articlesFree article

Inflammation, growth factors, and pulmonary vascular remodeling.

Hassoun PM, Mouthon L, Barberà JA, Eddahibi S, Flores SC, Grimminger F, Jones PL, Maitland ML, Michelakis ED, Morrell NW, Newman JH, Rabinovitch M, Schermuly R, Stenmark KR, Voelkel NF, Yuan JX, Humbert M.

J Am Coll Cardiol. 2009 Jun 30;54(1 Suppl):S10-9. Review.PMID: 19555853 [PubMed - indexed for MEDLINE]Related articles

Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma.

Voelkel NF, Spiegel S.

Immunol Cell Biol. 2009 Nov-Dec;87(8):601-5. Epub 2009 Jun 23.PMID: 19546879 [PubMed - in process]Related articles

Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways.

Mizuno S, Bogaard HJ, Voelkel NF, Umeda Y, Kadowaki M, Ameshima S, Miyamori I, Ishizaki T.

Respir Res. 2009 Mar 6;10:17.PMID: 19267931 [PubMed - indexed for MEDLINE]Related articlesFree article

The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension.

Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF.

Chest. 2009 Mar;135(3):794-804. Review.PMID: 19265089 [PubMed - indexed for MEDLINE]Related articles

IL-32-dependent effects of IL-1beta on endothelial cell functions.

Nold-Petry CA, Nold MF, Zepp JA, Kim SH, Voelkel NF, Dinarello CA.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3883-8. Epub 2009 Feb 19.PMID: 19228941 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effect of beraprost sodium, a stable prostacyclin analog, in the development of cigarette smoke extract-induced emphysema.

Chen Y, Hanaoka M, Chen P, Droma Y, Voelkel NF, Kubo K.

Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L648-56. Epub 2009 Feb 6.PMID: 19201816 [PubMed - indexed for MEDLINE]Related articles

Proactive integrated care improves quality of life in patients with COPD.

Koff PB, Jones RH, Cashman JM, Voelkel NF, Vandivier RW.

Eur Respir J. 2009 May;33(5):1031-8. Epub 2009 Jan 7.PMID: 19129289 [PubMed - indexed for MEDLINE]Related articles

Editors' perspective and conclusions.

Lederman MM, Sereni D, Simonneau G, Voelkel NF.

AIDS. 2008 Sep;22 Suppl 3:S63-7. No abstract available. PMID: 18845924 [PubMed - indexed for MEDLINE]Related articles

From viral infection to pulmonary arterial hypertension: a role for viral proteins?

Voelkel NF, Cool CD, Flores S.

AIDS. 2008 Sep;22 Suppl 3:S49-53. Review.PMID: 18845922 [PubMed - indexed for MEDLINE]Related articles

Pulmonary arterial hypertension and its association with HIV infection: an overview.

Lederman MM, Sereni D, Simonneau G, Voelkel NF.

AIDS. 2008 Sep;22 Suppl 3:S1-6. Review.PMID: 18845916 [PubMed - indexed for MEDLINE]Related articles

The cancer paradigm of severe pulmonary arterial hypertension.

Rai PR, Cool CD, King JA, Stevens T, Burns N, Winn RA, Kasper M, Voelkel NF.

Am J Respir Crit Care Med. 2008 Sep 15;178(6):558-64. Epub 2008 Jun 12.PMID: 18556624 [PubMed - indexed for MEDLINE]Related articlesFree article

Symposium: Thomas L. Petty Aspen Lung Conference: lung injury and repair. Conference summary.

Voelkel NF.

Proc Am Thorac Soc. 2008 Apr 15;5(3):354-7. No abstract available. PMID: 18403333 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular pathogenesis of emphysema.

Taraseviciene-Stewart L, Voelkel NF.

J Clin Invest. 2008 Feb;118(2):394-402. Review.PMID: 18246188 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary arterial remodeling induced by a Th2 immune response.

Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G.

J Exp Med. 2008 Feb 18;205(2):361-72. Epub 2008 Jan 28.PMID: 18227220 [PubMed - indexed for MEDLINE]Related articlesFree article

Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis.

Babu AN, Murakawa T, Thurman JM, Miller EJ, Henson PM, Zamora MR, Voelkel NF, Nicolls MR.

J Clin Invest. 2007 Dec;117(12):3774-85.PMID: 18060031 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells.

Sakao S, Taraseviciene-Stewart L, Cool CD, Tada Y, Kasahara Y, Kurosu K, Tanabe N, Takiguchi Y, Tatsumi K, Kuriyama T, Voelkel NF.

FASEB J. 2007 Nov;21(13):3640-52. Epub 2007 Jun 13.PMID: 17567571 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoxia and the lung: beyond hypoxic vasoconstriction.

Nicolls MR, Voelkel NF.

Antioxid Redox Signal. 2007 Jun;9(6):741-3.PMID: 17511589 [PubMed - indexed for MEDLINE]Related articles

Lipid A fraction of LPS induces a discrete MAPK activation in acute lung injury.

Fang WF, Cho JH, He Q, Lin MC, Wu CC, Voelkel NF, Douglas IS.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L336-44. Epub 2007 May 11.PMID: 17496062 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice.

Amura CR, Brodsky KS, Groff R, Gattone VH, Voelkel NF, Doctor RB.

Am J Physiol Cell Physiol. 2007 Jul;293(1):C419-28. Epub 2007 May 2.PMID: 17475663 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling.

Taraseviciene-Stewart L, Nicolls MR, Kraskauskas D, Scerbavicius R, Burns N, Cool C, Wood K, Parr JE, Boackle SA, Voelkel NF.

Am J Respir Crit Care Med. 2007 Jun 15;175(12):1280-9. Epub 2007 Apr 5.PMID: 17413127 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiogenesis in chronic lung disease.

Voelkel NF, Douglas IS, Nicolls M.

Chest. 2007 Mar;131(3):874-9. Review.PMID: 17356107 [PubMed - indexed for MEDLINE]Related articlesFree article

Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.

Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF.

Circ Res. 2007 Mar 30;100(6):923-9. Epub 2007 Mar 1.PMID: 17332430 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke.

Nana-Sinkam SP, Lee JD, Sotto-Santiago S, Stearman RS, Keith RL, Choudhury Q, Cool C, Parr J, Moore MD, Bull TM, Voelkel NF, Geraci MW.

Am J Respir Crit Care Med. 2007 Apr 1;175(7):676-85. Epub 2007 Jan 25.PMID: 17255567 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiling in pulmonary hypertension.

Bull TM, Coldren CD, Geraci MW, Voelkel NF.

Proc Am Thorac Soc. 2007 Jan;4(1):117-20. Review.PMID: 17202300 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury.

Hoke TS, Douglas IS, Klein CL, He Z, Fang W, Thurman JM, Tao Y, Dursun B, Voelkel NF, Edelstein CL, Faubel S.

J Am Soc Nephrol. 2007 Jan;18(1):155-64. Epub 2006 Dec 13.PMID: 17167117 [PubMed - indexed for MEDLINE]Related articlesFree article

The challenges of chronic obstructive pulmonary diseases (COPD)--a perspective.

Vandivier RW, Voelkel NF.

COPD. 2005 Mar;2(1):177-84. Review.PMID: 17136979 [PubMed - indexed for MEDLINE]Related articles

Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?

Taraseviciene-Stewart L, Douglas IS, Nana-Sinkam PS, Lee JD, Tuder RM, Nicolls MR, Voelkel NF.

Proc Am Thorac Soc. 2006 Nov;3(8):687-90. Review.PMID: 17065374 [PubMed - indexed for MEDLINE]Related articlesFree article

Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.

Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB; National Heart, Lung, and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure.

Circulation. 2006 Oct 24;114(17):1883-91. No abstract available. PMID: 17060398 [PubMed - indexed for MEDLINE]Related articlesFree article

N-acetylcysteine treatment protects against VEGF-receptor blockade-related emphysema.

Demura Y, Taraseviciene-Stewart L, Scerbavicius R, Tuder RM, Voelkel NF.

COPD. 2004 Apr;1(1):25-32.PMID: 16997736 [PubMed - indexed for MEDLINE]Related articles

Prostacyclin synthase in smoking-related lung disease.

Nana-Sinkam SP, Lee JD, Stearman R, Sakao S, Sotto-Santiago S, Voelkel NF, Geraci MW.

Proc Am Thorac Soc. 2006 Aug;3(6):517. No abstract available. PMID: 16921134 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of autoimmune emphysema.

Taraseviciene-Stewart L, Burns N, Kraskauskas D, Nicolls MR, Tuder RM, Voelkel NF.

Proc Am Thorac Soc. 2006 Aug;3(6):486-7. No abstract available. PMID: 16921121 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated oligoclonal CD4+ T cells in the lungs of patients with severe emphysema.

Sullivan AK, Simonian PL, Falta MT, Cosgrove GP, Brown KK, Kotzin BL, Voelkel NF, Fontenot AP.

Proc Am Thorac Soc. 2006 Aug;3(6):486. No abstract available. PMID: 16921120 [PubMed - indexed for MEDLINE]Related articlesFree article

The vasculature as a target in the treatment of pulmonary emphysema.

Golpon HA, Voelkel NF.

Curr Drug Targets. 2006 Jun;7(6):737-41. Review.PMID: 16787175 [PubMed - indexed for MEDLINE]Related articles

HIV-1 Nef is associated with complex pulmonary vascular lesions in SHIV-nef-infected macaques.

Marecki JC, Cool CD, Parr JE, Beckey VE, Luciw PA, Tarantal AF, Carville A, Shannon RP, Cota-Gomez A, Tuder RM, Voelkel NF, Flores SC.

Am J Respir Crit Care Med. 2006 Aug 15;174(4):437-45. Epub 2006 May 25.PMID: 16728715 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of right ventricular end-systolic regional wall stress in idiopathic pulmonary arterial hypertension: a new method for estimation of right ventricular wall stress.

Quaife RA, Chen MY, Lynch D, Badesch DB, Groves BM, Wolfel E, Robertson AD, Bristow MR, Voelkel NF.

Eur J Med Res. 2006 May 5;11(5):214-20.PMID: 16723296 [PubMed - indexed for MEDLINE]Related articles

Pulmonary flow reserve in children with idiopathic pulmonary arterial hypertension: implications for diagnosis and therapy.

Zimmermann R, Kreuder J, Michel-Behnke I, Voelkel NF, Schranz D.

Eur J Med Res. 2006 May 5;11(5):208-13.PMID: 16723295 [PubMed - indexed for MEDLINE]Related articles

Morphologic changes in explanted lungs after prostacyclin therapy for pulmonary hypertension.

Achcar RO, Yung GL, Saffer H, Cool CD, Voelkel NF, Yi ES.

Eur J Med Res. 2006 May 5;11(5):203-7.PMID: 16723294 [PubMed - indexed for MEDLINE]Related articles

Severe pulmonary hypertension in postmenopausal obese women.

Taraseviciute A, Voelkel NF.

Eur J Med Res. 2006 May 5;11(5):198-202.PMID: 16723293 [PubMed - indexed for MEDLINE]Related articles

Sarcoidois and pulmonary hypertension--a case report.

Tayal S, Voelkel NF, Rai PR, Cool CD.

Eur J Med Res. 2006 May 5;11(5):194-7.PMID: 16723292 [PubMed - indexed for MEDLINE]Related articles

Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension.

Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Cool C, Wood K, Tuder RM, Burns N, Kasper M, Voelkel NF.

Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L668-76. Epub 2006 May 12.PMID: 16698853 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis of pulmonary microvascular endothelial cells stimulates vascular smooth muscle cell growth.

Sakao S, Taraseviciene-Stewart L, Wood K, Cool CD, Voelkel NF.

Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L362-8. Epub 2006 Apr 14.PMID: 16617095 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of caveolin and heme oxygenase expression in severe pulmonary hypertension.

Achcar RO, Demura Y, Rai PR, Taraseviciene-Stewart L, Kasper M, Voelkel NF, Cool CD.

Chest. 2006 Mar;129(3):696-705.PMID: 16537870 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema.

Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, Tuder RM.

Am J Respir Crit Care Med. 2006 Jun 1;173(11):1222-8. Epub 2006 Mar 2.PMID: 16514110 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor in the lung.

Voelkel NF, Vandivier RW, Tuder RM.

Am J Physiol Lung Cell Mol Physiol. 2006 Feb;290(2):L209-21. Review.PMID: 16403941 [PubMed - indexed for MEDLINE]Related articlesFree article

Metastatic cancer while receiving continuous prostacyclin therapy.

Fagan KA, Bull TM, Badesch DB, Voelkel NF.

Chest. 2005 Dec;128(6 Suppl):619S-620S. No abstract available. PMID: 16373875 [PubMed - indexed for MEDLINE]Related articlesFree article