PubMed

Functional brown adipose tissue in healthy adults.

Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, Taittonen M, Laine J, Savisto NJ, Enerbäck S, Nuutila P.

N Engl J Med. 2009 Apr 9;360(15):1518-25. Erratum in: N Engl J Med. 2009 Sep 10;361(11):1123. PMID: 19357407 [PubMed - indexed for MEDLINE]Related articlesFree article

The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus.

Honka MJ, Vänttinen M, Iozzo P, Virtanen KA, Lautamäki R, Hällsten K, Borra RJ, Takala T, Viljanen AP, Kemppainen J, Pihlajamäki J, Knuuti J, Nuutila P, Laakso M.

Metabolism. 2009 Apr;58(4):541-6.PMID: 19303976 [PubMed - indexed for MEDLINE]Related articles

Pancreatic glucose uptake in vivo in men with newly diagnosed type 1 diabetes.

Kalliokoski T, Nuutila P, Virtanen KA, Iozzo P, Bucci M, Svedström E, Roivainen A, Någren K, Viljanen T, Minn H, Knuuti J, Rönnemaa T, Simell O.

J Clin Endocrinol Metab. 2008 May;93(5):1909-14. Epub 2008 Feb 19.PMID: 18285422 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene are associated with skeletal muscle glucose uptake.

Vänttinen M, Nuutila P, Kuulasmaa T, Pihlajamäki J, Hällsten K, Virtanen KA, Lautamäki R, Peltoniemi P, Takala T, Viljanen AP, Knuuti J, Laakso M.

Diabetes. 2005 Dec;54(12):3587-91.PMID: 16306381 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone treatment increases subcutaneous adipose tissue glucose uptake in parallel with perfusion in patients with type 2 diabetes: a double-blind, randomized study with metformin.

Viljanen AP, Virtanen KA, Järvisalo MJ, Hällsten K, Parkkola R, Rönnemaa T, Lönnqvist F, Iozzo P, Ferrannini E, Nuutila P.

J Clin Endocrinol Metab. 2005 Dec;90(12):6523-8. Epub 2005 Sep 27.PMID: 16189256 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study.

Virtanen KA, Iozzo P, Hällsten K, Huupponen R, Parkkola R, Janatuinen T, Lönnqvist F, Viljanen T, Rönnemaa T, Lönnroth P, Knuuti J, Ferrannini E, Nuutila P.

Diabetes. 2005 Sep;54(9):2720-6.PMID: 16123362 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.

Karlsson HK, Hällsten K, Björnholm M, Tsuchida H, Chibalin AV, Virtanen KA, Heinonen OJ, Lönnqvist F, Nuutila P, Zierath JR.

Diabetes. 2005 May;54(5):1459-67.PMID: 15855334 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study.

Vänttinen M, Nuutila P, Pihlajamäki J, Hällsten K, Virtanen KA, Lautamäki R, Peltoniemi P, Kemppainen J, Takala T, Viljanen AP, Knuuti J, Laakso M.

J Clin Endocrinol Metab. 2005 Jul;90(7):4249-54. Epub 2005 Apr 26.PMID: 15855261 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhancement of insulin-stimulated myocardial glucose uptake in patients with Type 2 diabetes treated with rosiglitazone.

Hällsten K, Virtanen KA, Lönnqvist F, Janatuinen T, Turiceanu M, Rönnemaa T, Viikari J, Lehtimäki T, Knuuti J, Nuutila P.

Diabet Med. 2004 Dec;21(12):1280-7.PMID: 15569129 [PubMed - indexed for MEDLINE]Related articles

Non-esterified fatty acids impair insulin-mediated glucose uptake and disposition in the liver.

Iozzo P, Lautamaki R, Geisler F, Virtanen KA, Oikonen V, Haaparanta M, Yki-Jarvinen H, Ferrannini E, Knuuti J, Nuutila P.

Diabetologia. 2004 Jul;47(7):1149-56. Epub 2004 Jul 9.PMID: 15243703 [PubMed - indexed for MEDLINE]Related articles

Effects of metformin and rosiglitazone monotherapy on insulin-mediated hepatic glucose uptake and their relation to visceral fat in type 2 diabetes.

Iozzo P, Hallsten K, Oikonen V, Virtanen KA, Parkkola R, Kemppainen J, Solin O, Lonnqvist F, Ferrannini E, Knuuti J, Nuutila P.

Diabetes Care. 2003 Jul;26(7):2069-74.PMID: 12832315 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-mediated hepatic glucose uptake is impaired in type 2 diabetes: evidence for a relationship with glycemic control.

Iozzo P, Hallsten K, Oikonen V, Virtanen KA, Kemppainen J, Solin O, Ferrannini E, Knuuti J, Nuutila P.

J Clin Endocrinol Metab. 2003 May;88(5):2055-60.PMID: 12727954 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of rosiglitazone and metformin on adipose tissue distribution and glucose uptake in type 2 diabetic subjects.

Virtanen KA, Hällsten K, Parkkola R, Janatuinen T, Lönnqvist F, Viljanen T, Rönnemaa T, Knuuti J, Huupponen R, Lönnroth P, Nuutila P.

Diabetes. 2003 Feb;52(2):283-90.PMID: 12540598 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone but not metformin enhances insulin- and exercise-stimulated skeletal muscle glucose uptake in patients with newly diagnosed type 2 diabetes.

Hällsten K, Virtanen KA, Lönnqvist F, Sipilä H, Oksanen A, Viljanen T, Rönnemaa T, Viikari J, Knuuti J, Nuutila P.

Diabetes. 2002 Dec;51(12):3479-85.PMID: 12453903 [PubMed - indexed for MEDLINE]Related articlesFree article

Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET.

Asola MR, Virtanen KA, Peltoniemi P, Någren K, Yu M, Mattila K, Jyrkkiö S, Metsärinne K, Nuutila P, Knuuti J.

Eur J Nucl Med Mol Imaging. 2002 Nov;29(11):1485-91. Epub 2002 Aug 30.PMID: 12397468 [PubMed - indexed for MEDLINE]Related articles

Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans.

Virtanen KA, Lönnroth P, Parkkola R, Peltoniemi P, Asola M, Viljanen T, Tolvanen T, Knuuti J, Rönnemaa T, Huupponen R, Nuutila P.

J Clin Endocrinol Metab. 2002 Aug;87(8):3902-10.PMID: 12161530 [PubMed - indexed for MEDLINE]Related articlesFree article

2-[(18)F]fluoro-2-deoxy-D-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats.

Virtanen KA, Haaparanta M, Grönroos T, Bergman J, Solin O, Rouru J, Nuutila P, Huupponen R.

Diabetes Obes Metab. 2002 Jan;4(1):60-8.PMID: 11874444 [PubMed - indexed for MEDLINE]Related articles

Human adipose tissue glucose uptake determined using [(18)F]-fluoro-deoxy-glucose ([(18)F]FDG) and PET in combination with microdialysis.

Virtanen KA, Peltoniemi P, Marjamäki P, Asola M, Strindberg L, Parkkola R, Huupponen R, Knuuti J, Lönnroth P, Nuutila P.

Diabetologia. 2001 Dec;44(12):2171-9.PMID: 11793018 [PubMed - indexed for MEDLINE]Related articles

Effects of estrous cycle and steroid replacement on the expression of leptin and uncoupling proteins in adipose tissue in the rat.

Luukkaa V, Savontaus E, Rouru J, Virtanen KA, Boss O, Huhtaniemi I, Koulu M, Pesonen U, Huupponen R.

Gynecol Endocrinol. 2001 Apr;15(2):103-12.PMID: 11379006 [PubMed - indexed for MEDLINE]Related articles

Chronic treatment with BRL 35135 potentiates the action of insulin on lipid metabolism.

Virtanen KA, Rouru J, Hänninen V, Savontaus E, Rouvari T, Teirmaa T, Koulu M, Huupponen R.

Eur J Pharmacol. 1997 Aug 6;332(2):215-8.PMID: 9286624 [PubMed - indexed for MEDLINE]Related articles