PubMed

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.

Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP.

Free Radic Biol Med. 2009 Oct 23. [Epub ahead of print]PMID: 19854266 [PubMed - as supplied by publisher]Related articles

Adaptation and failure of pancreatic {beta} cells in murine models with different degrees of metabolic syndrome.

Medina-Gomez G, Yetukuri L, Velagapudi V, Campbell M, Blount M, Jimenez-Linan M, Ros M, Oresic M, Vidal-Puig A.

Dis Model Mech. 2009 Nov-Dec;2(11-12):582-92. Epub 2009 Oct 19.PMID: 19841237 [PubMed - in process]Related articles

PPARs and adipocyte function.

Christodoulides C, Vidal-Puig A.

Mol Cell Endocrinol. 2009 Sep 20. [Epub ahead of print]PMID: 19772894 [PubMed - as supplied by publisher]Related articles

Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria.

Parker N, Crichton PG, Vidal-Puig AJ, Brand MD.

J Bioenerg Biomembr. 2009 Aug;41(4):335-42. Epub 2009 Aug 25.PMID: 19705265 [PubMed - in process]Related articles

Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels.

Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G, Schmidt S, Vidal-Puig A, Diano S, Andrews P, Brand MD, Friedman J.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13100-5. Epub 2009 Jul 21.PMID: 19622746 [PubMed - indexed for MEDLINE]Related articlesFree article

Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1.

Crichton PG, Parker N, Vidal-Puig AJ, Brand MD.

Biosci Rep. 2009 Jul 21. [Epub ahead of print]PMID: 19622065 [PubMed - as supplied by publisher]Related articles

Metabolic phenotyping of a model of adipocyte differentiation.

Roberts LD, Virtue S, Vidal-Puig A, Nicholls AW, Griffin JL.

Physiol Genomics. 2009 Oct 7;39(2):109-19. Epub 2009 Jul 14.PMID: 19602617 [PubMed - in process]Related articles

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

Parker N, Vidal-Puig AJ, Azzu V, Brand MD.

Biochim Biophys Acta. 2009 Dec;1787(12):1451-7. Epub 2009 Jun 17.PMID: 19539600 [PubMed - indexed for MEDLINE]Related articlesFree article

PGC-1beta: a co-activator that sets the tone for both basal and stress-stimulated mitochondrial activity.

Lelliott CJ, Vidal-Puig A.

Adv Exp Med Biol. 2009;646:133-9. Review.PMID: 19536672 [PubMed - indexed for MEDLINE]Related articles

Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice.

Kis A, Murdoch C, Zhang M, Siva A, Rodriguez-Cuenca S, Carobbio S, Lukasik A, Blount M, O'Rahilly S, Gray SL, Shah AM, Vidal-Puig A.

Eur J Heart Fail. 2009 Jun;11(6):533-41. Epub 2009 Apr 24.PMID: 19395708 [PubMed - indexed for MEDLINE]Related articlesFree article

CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.

Chavey C, Lazennec G, Lagarrigue S, Clapé C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L.

Cell Metab. 2009 Apr;9(4):339-49.PMID: 19356715 [PubMed - indexed for MEDLINE]Related articles

Integrating post-genomic approaches as a strategy to advance our understanding of health and disease.

Tang J, Tan CY, Oresic M, Vidal-Puig A.

Genome Med. 2009 Mar 30;1(3):35. [Epub ahead of print]PMID: 19341506 [PubMed - as supplied by publisher]Related articlesFree article

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.

Ishii KA, Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ, Vidal-Puig A, Ikeda K.

Nat Med. 2009 Mar;15(3):259-66. Epub 2009 Mar 1.PMID: 19252502 [PubMed - indexed for MEDLINE]Related articles

Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.

Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK.

Diabetes. 2009 Mar;58(3):609-19. Epub 2008 Dec 10.PMID: 19073771 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipogenesis and WNT signalling.

Christodoulides C, Lagathu C, Sethi JK, Vidal-Puig A.

Trends Endocrinol Metab. 2009 Jan;20(1):16-24. Epub 2008 Nov 13. Review.PMID: 19008118 [PubMed - indexed for MEDLINE]Related articles

Wnt signalling at the crossroads of nutritional regulation.

Sethi JK, Vidal-Puig AJ.

Biochem J. 2008 Dec 1;416(2):e11-3.PMID: 18990086 [PubMed - indexed for MEDLINE]Related articlesFree article

UCPs--unlikely calcium porters.

Brookes PS, Parker N, Buckingham JA, Vidal-Puig A, Halestrap AP, Gunter TE, Nicholls DG, Bernardi P, Lemasters JJ, Brand MD.

Nat Cell Biol. 2008 Nov;10(11):1235-7; author reply 1237-40. No abstract available. PMID: 18978830 [PubMed - indexed for MEDLINE]Related articlesFree article

AMPK: a metabolic gauge regulating whole-body energy homeostasis.

Lage R, Diéguez C, Vidal-Puig A, López M.

Trends Mol Med. 2008 Dec;14(12):539-49. Epub 2008 Nov 1. Review.PMID: 18977694 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.

Liesa M, Borda-d'Agua B, Medina-Gómez G, Lelliott CJ, Paz JC, Rojo M, Palacín M, Vidal-Puig A, Zorzano A.

PLoS One. 2008;3(10):e3613. Epub 2008 Oct 31.PMID: 18974884 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipidomics: a new window to biomedical frontiers.

Oresic M, Hänninen VA, Vidal-Puig A.

Trends Biotechnol. 2008 Dec;26(12):647-52. Epub 2008 Oct 23.PMID: 18951641 [PubMed - indexed for MEDLINE]Related articles

Adipose tissue expandability and the metabolic syndrome.

Slawik M, Vidal-Puig AJ.

Genes Nutr. 2007 Oct;2(1):41-5. No abstract available. PMID: 18850138 [PubMed - in process]Related articlesFree article

It's not how fat you are, it's what you do with it that counts.

Virtue S, Vidal-Puig A.

PLoS Biol. 2008 Sep 23;6(9):e237. No abstract available. PMID: 18816166 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese.

Tan CY, Vidal-Puig A.

Biochem Soc Trans. 2008 Oct;36(Pt 5):935-40. Review.PMID: 18793164 [PubMed - indexed for MEDLINE]Related articles

Brain lipogenesis and regulation of energy metabolism.

López M, Vidal-Puig A.

Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):483-90. Review.PMID: 18542011 [PubMed - indexed for MEDLINE]Related articles

Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion.

Vázquez MJ, González CR, Varela L, Lage R, Tovar S, Sangiao-Alvarellos S, Williams LM, Vidal-Puig A, Nogueiras R, López M, Diéguez C.

Endocrinology. 2008 Sep;149(9):4534-43. Epub 2008 May 22.PMID: 18499762 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Alvarez CV, Gallego R, Lelliott CJ, Carling D, Tschöp MH, Diéguez C, Vidal-Puig A.

Cell Metab. 2008 May;7(5):389-99.PMID: 18460330 [PubMed - indexed for MEDLINE]Related articles

Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.

Barber TM, Hazell M, Christodoulides C, Golding SJ, Alvey C, Burling K, Vidal-Puig A, Groome NP, Wass JA, Franks S, McCarthy MI.

J Clin Endocrinol Metab. 2008 Jul;93(7):2859-65. Epub 2008 Apr 29.PMID: 18445670 [PubMed - indexed for MEDLINE]Related articlesFree article

Current challenges in metabolomics for diabetes research: a vital functional genomic tool or just a ploy for gaining funding?

Griffin JL, Vidal-Puig A.

Physiol Genomics. 2008 Jun 12;34(1):1-5. Epub 2008 Apr 15.PMID: 18413782 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential.

Parker N, Vidal-Puig A, Brand MD.

Biosci Rep. 2008 Apr;28(2):83-8.PMID: 18384278 [PubMed - indexed for MEDLINE]Related articlesFree article

Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.

Nogueiras R, López M, Lage R, Perez-Tilve D, Pfluger P, Mendieta-Zerón H, Sakkou M, Wiedmer P, Benoit SC, Datta R, Dong JZ, Culler M, Sleeman M, Vidal-Puig A, Horvath T, Treier M, Diéguez C, Tschöp MH.

Endocrinology. 2008 Jun;149(6):3009-15. Epub 2008 Feb 28.PMID: 18308842 [PubMed - indexed for MEDLINE]Related articlesFree article

The metabolic profile of early Huntington's disease--a combined human and transgenic mouse study.

Goodman AO, Murgatroyd PR, Medina-Gomez G, Wood NI, Finer N, Vidal-Puig AJ, Morton AJ, Barker RA.

Exp Neurol. 2008 Apr;210(2):691-8. Epub 2008 Jan 19.PMID: 18284928 [PubMed - indexed for MEDLINE]Related articles

Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.

Parker N, Affourtit C, Vidal-Puig A, Brand MD.

Biochem J. 2008 May 15;412(1):131-9.PMID: 18251717 [PubMed - indexed for MEDLINE]Related articlesFree article

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA.

PLoS Med. 2008 Jan 29;5(1):e27. Erratum in: PLoS Med. 2008 Dec;5(12):e246.. Solanky, Bhavana [added]; Deelchand, Dinesh [added]. PMID: 18232732 [PubMed - indexed for MEDLINE]Related articlesFree article

Informatics and computational strategies for the study of lipids.

Yetukuri L, Ekroos K, Vidal-Puig A, Oresic M.

Mol Biosyst. 2008 Feb;4(2):121-7. Epub 2007 Dec 18. Review.PMID: 18213405 [PubMed - indexed for MEDLINE]Related articles

Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide.

Adams BA, Gray SL, Isaac ER, Bianco AC, Vidal-Puig AJ, Sherwood NM.

Endocrinology. 2008 Apr;149(4):1571-80. Epub 2007 Dec 27.PMID: 18162530 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical assessment of the current guidelines for the management and treatment of morbidly obese patients.

Burguera B, Agusti A, Arner P, Baltasar A, Barbe F, Barcelo A, Breton I, Cabanes T, Casanueva FF, Couce ME, Dieguez C, Fiol M, Fernandez Real JM, Formiguera X, Fruhbeck G, Garcia Romero M, Garcia Sanz M, Ghigo E, Gomis R, Higa K, Ibarra O, Lacy A, Larrad A, Masmiquel L, Moizé V, Moreno B, Moreiro J, Ricart W, Riesco M, Salinas R, Salvador J, Pi-Sunyer FX, Scopinaro N, Sjostrom L, Pagan A, Pereg V, Sánchez Pernaute A, Torres A, Urgeles JR, Vidal-Puig A, Vidal J, Vila M.

J Endocrinol Invest. 2007 Nov;30(10):844-52.PMID: 18075287 [PubMed - indexed for MEDLINE]Related articles

Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1).

Medina-Gomez G, Gray S, Vidal-Puig A.

Public Health Nutr. 2007 Oct;10(10A):1132-7. Review.PMID: 17903321 [PubMed - indexed for MEDLINE]Related articles

Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules.

Schinner S, Ulgen F, Papewalis C, Schott M, Woelk A, Vidal-Puig A, Scherbaum WA.

Diabetologia. 2008 Jan;51(1):147-54. Epub 2007 Nov 10.PMID: 17994217 [PubMed - indexed for MEDLINE]Related articles

A MUFA-rich diet improves posprandial glucose, lipid and GLP-1 responses in insulin-resistant subjects.

Paniagua JA, de la Sacristana AG, Sánchez E, Romero I, Vidal-Puig A, Berral FJ, Escribano A, Moyano MJ, Peréz-Martinez P, López-Miranda J, Pérez-Jiménez F.

J Am Coll Nutr. 2007 Oct;26(5):434-44.PMID: 17914131 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

Chakravarthy MV, Zhu Y, López M, Yin L, Wozniak DF, Coleman T, Hu Z, Wolfgang M, Vidal-Puig A, Lane MD, Semenkovich CF.

J Clin Invest. 2007 Sep;117(9):2539-52.PMID: 17694178 [PubMed - indexed for MEDLINE]Related articlesFree article

Orexin expression is regulated by alpha-melanocyte-stimulating hormone.

López M, Lage R, Tung YC, Challis BG, Varela L, Virtue S, O'Rahilly S, Vidal-Puig A, Diéguez C, Coll AP.

J Neuroendocrinol. 2007 Sep;19(9):703-7.PMID: 17680885 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue expandability in the maintenance of metabolic homeostasis.

Gray SL, Vidal-Puig AJ.

Nutr Rev. 2007 Jun;65(6 Pt 2):S7-12. Review.PMID: 17605308 [PubMed - indexed for MEDLINE]Related articles

Targeting fat to prevent diabetes.

Sethi JK, Vidal-Puig AJ.

Cell Metab. 2007 May;5(5):323-5.PMID: 17488634 [PubMed - indexed for MEDLINE]Related articles

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A.

PLoS Genet. 2007 Apr 27;3(4):e64.PMID: 17465682 [PubMed - indexed for MEDLINE]Related articlesFree article

Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis.

Yetukuri L, Katajamaa M, Medina-Gomez G, Seppänen-Laakso T, Vidal-Puig A, Oresic M.

BMC Syst Biol. 2007 Feb 15;1:12.PMID: 17408502 [PubMed - indexed for MEDLINE]Related articlesFree article

Monounsaturated fat-rich diet prevents central body fat distribution and decreases postprandial adiponectin expression induced by a carbohydrate-rich diet in insulin-resistant subjects.

Paniagua JA, Gallego de la Sacristana A, Romero I, Vidal-Puig A, Latre JM, Sanchez E, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F.

Diabetes Care. 2007 Jul;30(7):1717-23. Epub 2007 Mar 23.PMID: 17384344 [PubMed - indexed for MEDLINE]Related articlesFree article

Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation.

Sethi JK, Vidal-Puig AJ.

J Lipid Res. 2007 Jun;48(6):1253-62. Epub 2007 Mar 20. Review.PMID: 17374880 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake.

López M, Lelliott CJ, Vidal-Puig A.

Bioessays. 2007 Mar;29(3):248-61. Review.PMID: 17295284 [PubMed - indexed for MEDLINE]Related articles

IGF-binding protein-2 protects against the development of obesity and insulin resistance.

Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA.

Diabetes. 2007 Feb;56(2):285-94.PMID: 17259371 [PubMed - indexed for MEDLINE]Related articlesFree article

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K, Campbell M, Hu P, Zhang D, Litwin SE, Zaha VG, Fountain KT, Boudina S, Jimenez-Linan M, Blount M, Lopez M, Meirhaeghe A, Bohlooly-Y M, Storlien L, Strömstedt M, Snaith M, Oresic M, Abel ED, Cannon B, Vidal-Puig A.

PLoS Biol. 2006 Nov;4(11):e369.PMID: 17090215 [PubMed - indexed for MEDLINE]Related articlesFree article