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Down-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicity.
Veluthakal R, Suresh MV, Kowluru A.
Mol Cell Biochem. 2009 Sep;329(1-2):121-9. Epub 2009 Apr 15.PMID: 19367376 [PubMed - indexed for MEDLINE]Related articles
A novel histone deacetylase inhibitor prevents IL-1beta-induced metabolic dysfunction in pancreatic beta-cells.
Susick L, Senanayake T, Veluthakal R, Woster PM, Kowluru A.
J Cell Mol Med. 2009 Jan 28. [Epub ahead of print]PMID: 19187126 [PubMed - as supplied by publisher]Related articles
Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells.
Veluthakal R, Madathilparambil SV, McDonald P, Olson LK, Kowluru A.
Biochem Pharmacol. 2009 Jan 1;77(1):101-13. Epub 2008 Sep 27.PMID: 18930714 [PubMed - indexed for MEDLINE]Related articles
Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells.
Susick L, Veluthakal R, Suresh MV, Hadden T, Kowluru A.
J Cell Mol Med. 2008 Sep-Oct;12(5A):1571-83. Epub 2007 Dec 5.PMID: 18053091 [PubMed - indexed for MEDLINE]Related articles
Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic beta-cells.
Jangati GR, Veluthakal R, Susick L, Gruber SA, Kowluru A.
Endocrine. 2007 Jun;31(3):248-53.PMID: 17906371 [PubMed - indexed for MEDLINE]Related articles
Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells.
Veluthakal R, Kaur H, Goalstone M, Kowluru A.
Diabetes. 2007 Jan;56(1):204-10.PMID: 17192483 [PubMed - indexed for MEDLINE]Related articlesFree article
IL-1beta-induced iNOS expression, NO release and loss in metabolic cell viability are resistant to inhibitors of ceramide synthase and sphingomyelinase in INS 832/13 cells.
Veluthakal R, Jangati GR, Kowluru A.
JOP. 2006 Nov 10;7(6):593-601.PMID: 17095838 [PubMed - indexed for MEDLINE]Related articlesFree article
Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells.
McDonald P, Veluthakal R, Kaur H, Kowluru A.
Am J Physiol Cell Physiol. 2007 Mar;292(3):C1216-20. Epub 2006 Oct 11.PMID: 17035298 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulatory roles for nm23/nucleoside diphosphate kinase-like enzymes in insulin secretion from the pancreatic islet beta cell.
Kowluru A, Veluthakal R, Kaetzel DM.
J Bioenerg Biomembr. 2006 Aug;38(3-4):227-32.PMID: 16957985 [PubMed - indexed for MEDLINE]Related articles
siRNA-mediated depletion of endogenous protein phosphatase 2Acalpha markedly attenuates ceramide-activated protein phosphatase activity in insulin-secreting INS-832/13 cells.
Jangati GR, Veluthakal R, Kowluru A.
Biochem Biophys Res Commun. 2006 Sep 22;348(2):649-52. Epub 2006 Jul 28.PMID: 16884689 [PubMed - indexed for MEDLINE]Related articles
Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells: potential regulation by IL-1beta.
Veluthakal R, Wadzinski BE, Kowluru A.
Apoptosis. 2006 Aug;11(8):1401-11.PMID: 16830232 [PubMed - indexed for MEDLINE]Related articles
Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.
Kowluru A, Veluthakal R.
Diabetes. 2005 Dec;54(12):3523-9.PMID: 16306371 [PubMed - indexed for MEDLINE]Related articlesFree article
Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: potential mechanisms underlying ceramide-mediated metabolic dysfunction of the beta cell.
Veluthakal R, Palanivel R, Zhao Y, McDonald P, Gruber S, Kowluru A.
Apoptosis. 2005 Aug;10(4):841-50.PMID: 16133874 [PubMed - indexed for MEDLINE]Related articles
Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+.
Veluthakal R, Chvyrkova I, Tannous M, McDonald P, Amin R, Hadden T, Thurmond DC, Quon MJ, Kowluru A.
Diabetes. 2005 Sep;54(9):2576-85.PMID: 16123345 [PubMed - indexed for MEDLINE]Related articlesFree article
Further evidence for the regulation of acetyl-CoA carboxylase activity by a glutamate- and magnesium-activated protein phosphatase in the pancreatic beta cell: defective regulation in the diabetic GK rat islet.
Palanivel R, Veluthakal R, McDonald P, Kowluru A.
Endocrine. 2005 Feb;26(1):71-7.PMID: 15805588 [PubMed - indexed for MEDLINE]Related articles
Interleukin-1 beta induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cells.
Veluthakal R, Amin R, Kowluru A.
Am J Physiol Cell Physiol. 2004 Oct;287(4):C1152-62. Epub 2004 Jun 16.PMID: 15201138 [PubMed - indexed for MEDLINE]Related articlesFree article
GTP-binding protein-independent potentiation by mastoparan of IL-1beta-induced nitric oxide release from insulin-secreting HIT-T15 cells.
Chen HQ, Veluthakal R, Palanivel R, Kowluru A.
Apoptosis. 2004 Mar;9(2):145-8.PMID: 15004511 [PubMed - indexed for MEDLINE]Related articles
Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells.
Palanivel R, Veluthakal R, Kowluru A.
Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1032-41. Epub 2004 Feb 17.PMID: 14970009 [PubMed - indexed for MEDLINE]Related articlesFree article
Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells.
Chen HQ, Tannous M, Veluthakal R, Amin R, Kowluru A.
Biochem Pharmacol. 2003 Nov 1;66(9):1681-94.PMID: 14563479 [PubMed - indexed for MEDLINE]Related articles
Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins.
Amin RH, Chen HQ, Veluthakal R, Silver RB, Li J, Li G, Kowluru A.
Endocrinology. 2003 Oct;144(10):4508-18. Epub 2003 Jun 19.PMID: 12960065 [PubMed - indexed for MEDLINE]Related articlesFree article
IL-1beta-induced nitric oxide release from insulin-secreting beta-cells: further evidence for the involvement of GTP-binding proteins.
Tannous M, Veluthakal R, Amin R, Kowluru A.
Diabetes Metab. 2002 Dec;28(6 Pt 2):3S78-84; discussion 3S108-12.PMID: 12688637 [PubMed - indexed for MEDLINE]Related articles
Functional inactivation by interleukin-1beta of glyceraldehyde-3-phosphate dehydrogenase in insulin-secreting cells.
Veluthakal R, Khan I, Tannous M, Kowluru A.
Apoptosis. 2002 Jun;7(3):241-6.PMID: 11997668 [PubMed - indexed for MEDLINE]Related articles
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