PubMed

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Drijfhout JW, Ossendorp F, Roep BO, Peakman M.

J Clin Invest. 2008 Oct;118(10):3390-402. Erratum in: J Clin Invest. 2009 Sep;119(9):2844. Unger, Wendy [corrected to Unger, Wendy W]. PMID: 18802479 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the capsid protein VP4 in the plasma-dependent enhancement of the Coxsackievirus B4E2-infection of human peripheral blood cells.

Sauter P, Lobert PE, Lucas B, Varela-Calvino R, Alm G, Wattre P, Hober D.

Virus Res. 2007 May;125(2):183-90. Epub 2007 Feb 8.PMID: 17291618 [PubMed - indexed for MEDLINE]Related articles

Tissue-polypeptide-specific antigen levels in diabetic patients with normal and pathological biochemical profiles.

Rodriguez J, Varela-Calviño R, Garrido Outeiriño M, Rodríguez-Segade S, Camiña F.

Clin Biochem. 2007 Feb;40(3-4):278-81. Epub 2006 Dec 5.PMID: 17208209 [PubMed - indexed for MEDLINE]Related articles

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.

Ellis RJ, Varela-Calvino R, Tree TI, Peakman M.

Immunology. 2005 Nov;116(3):337-46.PMID: 16236123 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein.

Varela-Calvino R, Skowera A, Arif S, Peakman M.

J Virol. 2004 Dec;78(24):13399-408.PMID: 15564450 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular immune activation in Gulf War veterans.

Skowera A, Hotopf M, Sawicka E, Varela-Calvino R, Unwin C, Nikolaou V, Hull L, Ismail K, David AS, Wessely SC, Peakman M.

J Clin Immunol. 2004 Jan;24(1):66-73.PMID: 14997036 [PubMed - indexed for MEDLINE]Related articles

Enteroviruses and type 1 diabetes.

Varela-Calvino R, Peakman M.

Diabetes Metab Res Rev. 2003 Nov-Dec;19(6):431-41. Review.PMID: 14648802 [PubMed - indexed for MEDLINE]Related articles

Characterization of the T-cell response to coxsackievirus B4: evidence that effector memory cells predominate in patients with type 1 diabetes.

Varela-Calvino R, Ellis R, Sgarbi G, Dayan CM, Peakman M.

Diabetes. 2002 Jun;51(6):1745-53.PMID: 12031961 [PubMed - indexed for MEDLINE]Related articlesFree article

3 beta hydroxysteroid dehydrogenase autoantibodies in patients with idiopathic premature ovarian failure target N- and C-terminal epitopes.

Arif S, Varela-Calvino R, Conway GS, Peakman M.

J Clin Endocrinol Metab. 2001 Dec;86(12):5892-7.PMID: 11739460 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell activation by coxsackievirus B4 antigens in type 1 diabetes mellitus: evidence for selective TCR Vbeta usage without superantigenic activity.

Varela-Calvino R, Sgarbi G, Wedderburn LR, Dayan CM, Tremble J, Peakman M.

J Immunol. 2001 Sep 15;167(6):3513-20.PMID: 11544345 [PubMed - indexed for MEDLINE]Related articlesFree article

T-Cell reactivity to the P2C nonstructural protein of a diabetogenic strain of coxsackievirus B4.

Varela-Calvino R, Sgarbi G, Arif S, Peakman M.

Virology. 2000 Aug 15;274(1):56-64.PMID: 10936088 [PubMed - indexed for MEDLINE]Related articles