PubMed

The R1141X Loss-of-Function Mutation of the ABCC6 Gene Is a Strong Genetic Risk Factor for Coronary Artery Disease.

Köblös G, Andrikovics H, Prohászka Z, Tordai A, Váradi A, Arányi T.

Genet Test Mol Biomarkers. 2009 Nov 23. [Epub ahead of print]PMID: 19929409 [PubMed - as supplied by publisher]

Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties.

Hegedus C, Ozvegy-Laczka C, Apáti A, Magócsi M, Német K, Orfi L, Kéri G, Katona M, Takáts Z, Váradi A, Szakács G, Sarkadi B.

Br J Pharmacol. 2009 Oct;158(4):1153-64. Epub 2009 Sep 28.PMID: 19785662 [PubMed - in process]Related articles

Clustering of disease-causing mutations on the domain-domain interfaces of ABCC6.

Fülöp K, Barna L, Symmons O, Závodszky P, Váradi A.

Biochem Biophys Res Commun. 2009 Feb 13;379(3):706-9. Epub 2009 Jan 6.PMID: 19133228 [PubMed - indexed for MEDLINE]Related articles

The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues.

Szeri F, Iliás A, Pomozi V, Robinow S, Bakos E, Váradi A.

Biochim Biophys Acta. 2009 Feb;1788(2):402-9. Epub 2008 Nov 20.PMID: 19059376 [PubMed - indexed for MEDLINE]Related articles

Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms.

Li Q, Jiang Q, Pfendner E, Váradi A, Uitto J.

Exp Dermatol. 2009 Jan;18(1):1-11. Epub 2008 Oct 22. Review.PMID: 19054062 [PubMed - indexed for MEDLINE]Related articles

Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs.

Váradi A, Tusnády GE, Bakos E, Sarkadi B.

Cytotechnology. 1998 Sep;27(1-3):71-9. No abstract available. PMID: 19002784 [PubMed - in process]Related articles

[Assumption of medical risks and the problem of medical liability in ancient Roman law]

Váradi A.

Orv Hetil. 2008 Nov 2;149(44):2091-3. Hungarian. PMID: 18952529 [PubMed - indexed for MEDLINE]Related articles

How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes.

Symmons O, Váradi A, Arányi T.

Mol Biol Evol. 2008 Dec;25(12):2601-13. Epub 2008 Sep 12.PMID: 18791038 [PubMed - indexed for MEDLINE]Related articles

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.

Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B.

J Biol Chem. 2008 Sep 19;283(38):26059-70. Epub 2008 Jul 21.PMID: 18644784 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

Szakács G, Váradi A, Ozvegy-Laczka C, Sarkadi B.

Drug Discov Today. 2008 May;13(9-10):379-93. Epub 2008 Feb 20. Review.PMID: 18468555 [PubMed - indexed for MEDLINE]Related articles

[Preliminary data of life and health insurance in the Roman Law (The collegium funeraticium and the collegium tenuiorum)]

Váradi A.

Orv Hetil. 2007 Dec 30;148(52):2477-81. Hungarian. PMID: 18079095 [PubMed - indexed for MEDLINE]Related articles

External cell control polymerase chain reaction: replacing internal standards with an unbiased strategy for quantitative polymerase chain reaction normalization.

Bors A, Ribiczey P, Köblös G, Brózik A, Ujfaludi Z, Magócsi M, Váradi A, Tordai A, Kovács T, Arányi T.

Anal Biochem. 2008 Jan 15;372(2):261-3. Epub 2007 Aug 24. No abstract available. PMID: 17945177 [PubMed - indexed for MEDLINE]Related articles

Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.

Telbisz A, Müller M, Ozvegy-Laczka C, Homolya L, Szente L, Váradi A, Sarkadi B.

Biochim Biophys Acta. 2007 Nov;1768(11):2698-713. Epub 2007 Jul 10.PMID: 17662239 [PubMed - indexed for MEDLINE]Related articles

Are you listening?

Varadi A.

JCCA J Can Chiropr Assoc. 2005 Sep;49(3):137-40. No abstract available. PMID: 17549128 [PubMed - in process]Related articlesFree article

mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in NTERA2 human embryonic carcinoma cell-derived neurons.

Park H, Váradi A, Seok H, Jo J, Gilpin H, Liew CG, Jung S, Andrews PW, Molnár E, Cho K.

Neuropharmacology. 2007 May;52(6):1403-14. Epub 2007 Feb 21.PMID: 17395218 [PubMed - indexed for MEDLINE]Related articles

Developing oligodendrocytes express functional GABA(B) receptors that stimulate cell proliferation and migration.

Luyt K, Slade TP, Dorward JJ, Durant CF, Wu Y, Shigemoto R, Mundell SJ, Váradi A, Molnár E.

J Neurochem. 2007 Feb;100(3):822-40. Epub 2006 Nov 27.PMID: 17144904 [PubMed - indexed for MEDLINE]Related articles

Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity.

Müller M, Klein I, Kopácsi S, Remaley AT, Rajnavölgyi E, Sarkadi B, Váradi A.

FEBS Lett. 2006 Nov 13;580(26):6139-44. Epub 2006 Oct 16.PMID: 17055487 [PubMed - indexed for MEDLINE]Related articles

The BiSearch web server.

Arányi T, Váradi A, Simon I, Tusnády GE.

BMC Bioinformatics. 2006 Oct 5;7:431.PMID: 17022803 [PubMed - indexed for MEDLINE]Related articlesFree article

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.

Sarkadi B, Homolya L, Szakács G, Váradi A.

Physiol Rev. 2006 Oct;86(4):1179-236. Review.PMID: 17015488 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotype-phenotype correlations in Hungarian patients with hereditary medullary thyroid cancer.

Patocs A, Klein I, Szilvasi A, Gergics P, Toth M, Valkusz Z, Forizs E, Igaz P, Al-Farhat Y, Tordai A, Varadi A, Racz K, Esik O.

Wien Klin Wochenschr. 2006 Jul;118(13-14):417-21.PMID: 16865647 [PubMed - indexed for MEDLINE]Related articles

Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.

Luyt K, Váradi A, Durant CF, Molnár E.

J Neurochem. 2006 Oct;99(2):641-56. Epub 2006 Jul 6.PMID: 16836654 [PubMed - indexed for MEDLINE]Related articles

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis.

Varadi A, Grant A, McCormack M, Nicolson T, Magistri M, Mitchell KJ, Halestrap AP, Yuan H, Schwappach B, Rutter GA.

Diabetologia. 2006 Jul;49(7):1567-77. Epub 2006 May 12.PMID: 16752175 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion in health and disease: genomics, proteomics and single vesicle dynamics.

Rutter GA, Varadi A, Tsuboi T, Parton L, Ravier M.

Biochem Soc Trans. 2006 Apr;34(Pt 2):247-50. Review.PMID: 16545086 [PubMed - indexed for MEDLINE]Related articles

The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.

Cervenak J, Andrikovics H, Ozvegy-Laczka C, Tordai A, Német K, Váradi A, Sarkadi B.

Cancer Lett. 2006 Mar 8;234(1):62-72. Epub 2005 Dec 7. Review.PMID: 16337740 [PubMed - indexed for MEDLINE]Related articles

Membrane topology of human ABC proteins.

Tusnády GE, Sarkadi B, Simon I, Váradi A.

FEBS Lett. 2006 Feb 13;580(4):1017-22. Epub 2005 Dec 1. Review.PMID: 16337630 [PubMed - indexed for MEDLINE]Related articles

Production of a truncated soluble human semicarbazide-sensitive amine oxidase mediated by a GST-fusion protein secreted from HEK293 cells.

Ohman J, Jakobsson E, Källström U, Elmblad A, Ansari A, Kalderén C, Robertson E, Danielsson E, Gustavsson AL, Varadi A, Ekblom J, Holmgren E, Doverskog M, Abrahmsén L, Nilsson J.

Protein Expr Purif. 2006 Apr;46(2):321-31. Epub 2005 Nov 17.PMID: 16325418 [PubMed - indexed for MEDLINE]Related articles

Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells.

Varadi A, Tsuboi T, Rutter GA.

Mol Biol Cell. 2005 Jun;16(6):2670-80. Epub 2005 Mar 23.PMID: 15788565 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.

Arányi T, Ratajewski M, Bardóczy V, Pulaski L, Bors A, Tordai A, Váradi A.

J Biol Chem. 2005 May 13;280(19):18643-50. Epub 2005 Mar 9.PMID: 15760889 [PubMed - indexed for MEDLINE]Related articlesFree article

Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).

Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O, Szabó K, Homolya L, Váradi A, Buday L, Kéri G, Német K, Sarkadi B.

Cancer Res. 2005 Mar 1;65(5):1770-7.PMID: 15753373 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional expression of a multidrug P-glycoprotein transporter of Leishmania.

Cortés-Selva F, Muñoz-Martínez F, Iliás A, Jiménez AI, Váradi A, Gamarro F, Castanys S.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):502-7.PMID: 15737615 [PubMed - indexed for MEDLINE]Related articles

Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.

Ozvegy-Laczka C, Köblös G, Sarkadi B, Váradi A.

Biochim Biophys Acta. 2005 Feb 1;1668(1):53-63.PMID: 15670731 [PubMed - indexed for MEDLINE]Related articles

BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes.

Tusnády GE, Simon I, Váradi A, Arányi T.

Nucleic Acids Res. 2005 Jan 13;33(1):e9.PMID: 15653630 [PubMed - indexed for MEDLINE]Related articlesFree article

Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.

Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B.

J Biol Chem. 2005 Feb 11;280(6):4219-27. Epub 2004 Nov 22.PMID: 15557326 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial localization as a determinant of capacitative Ca2+ entry in HeLa cells.

Varadi A, Cirulli V, Rutter GA.

Cell Calcium. 2004 Dec;36(6):499-508.PMID: 15488599 [PubMed - indexed for MEDLINE]Related articles

The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.

Tarnay JN, Szeri F, Iliás A, Annilo T, Sung C, Le Saux O, Váradi A, Dean M, Boyd CD, Robinow S.

Insect Mol Biol. 2004 Oct;13(5):539-48.PMID: 15373810 [PubMed - indexed for MEDLINE]Related articles

Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1.

Varadi A, Johnson-Cadwell LI, Cirulli V, Yoon Y, Allan VJ, Rutter GA.

J Cell Sci. 2004 Sep 1;117(Pt 19):4389-400. Epub 2004 Aug 10.PMID: 15304525 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of mitochondrial Na+-Ca2+ exchange restores agonist-induced ATP production and Ca2+ handling in human complex I deficiency.

Visch HJ, Rutter GA, Koopman WJ, Koenderink JB, Verkaart S, de Groot T, Varadi A, Mitchell KJ, van den Heuvel LP, Smeitink JA, Willems PH.

J Biol Chem. 2004 Sep 24;279(39):40328-36. Epub 2004 Jul 21.PMID: 15269216 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

Szentpétery Z, Kern A, Liliom K, Sarkadi B, Váradi A, Bakos E.

J Biol Chem. 2004 Oct 1;279(40):41670-8. Epub 2004 Jul 12.PMID: 15252017 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization.

Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Váradi A, Sarkadi B, Elkind NB.

Biochem Biophys Res Commun. 2004 Jul 30;320(3):860-7.PMID: 15240127 [PubMed - indexed for MEDLINE]Related articles

Ca2+-induced Ca2+ release in pancreatic islet beta-cells: critical evaluation of the use of endoplasmic reticulum-targeted "cameleons".

Varadi A, Rutter GA.

Endocrinology. 2004 Oct;145(10):4540-9. Epub 2004 Jun 24.PMID: 15217981 [PubMed - indexed for MEDLINE]Related articlesFree article

ABCG2 -- a transporter for all seasons.

Sarkadi B, Ozvegy-Laczka C, Német K, Váradi A.

FEBS Lett. 2004 Jun 1;567(1):116-20. Review.PMID: 15165903 [PubMed - indexed for MEDLINE]Related articles

Metabotropic glutamate receptors are expressed in adult human glial progenitor cells.

Luyt K, Varadi A, Halfpenny CA, Scolding NJ, Molnar E.

Biochem Biophys Res Commun. 2004 Jun 18;319(1):120-9.PMID: 15158450 [PubMed - indexed for MEDLINE]Related articles

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B.

Mol Pharmacol. 2004 Jun;65(6):1485-95.PMID: 15155841 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional studies on the MRP1 multidrug transporter: characterization of ABC-signature mutant variants.

Szentpétery Z, Sarkadi B, Bakos E, Váradi A.

Anticancer Res. 2004 Mar-Apr;24(2A):449-55.PMID: 15152943 [PubMed - indexed for MEDLINE]Related articles

Nucleotides and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1 multidrug transporter.

Kern A, Szentpétery Z, Liliom K, Bakos E, Sarkadi B, Váradi A.

Biochem J. 2004 Jun 1;380(Pt 2):549-60.PMID: 14759224 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells.

Varadi A, Tsuboi T, Johnson-Cadwell LI, Allan VJ, Rutter GA.

Biochem Biophys Res Commun. 2003 Nov 14;311(2):272-82.PMID: 14592410 [PubMed - indexed for MEDLINE]Related articles

Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.

Sinkó E, Iliás A, Ujhelly O, Homolya L, Scheffer GL, Bergen AA, Sarkadi B, Váradi A.

Biochem Biophys Res Commun. 2003 Aug 22;308(2):263-9.PMID: 12901863 [PubMed - indexed for MEDLINE]Related articles

Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate.

Homolya L, Váradi A, Sarkadi B.

Biofactors. 2003;17(1-4):103-14. Review.PMID: 12897433 [PubMed - indexed for MEDLINE]Related articles

Analysis of large structural changes of the factor VIII gene, involving intron 1 and 22, in severe hemophilia A.

Andrikovics H, Klein I, Bors A, Nemes L, Marosi A, Váradi A, Tordai A.

Haematologica. 2003 Jul;88(7):778-84.PMID: 12857556 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

Bodo A, Bakos E, Szeri F, Varadi A, Sarkadi B.

J Biol Chem. 2003 Jun 27;278(26):23529-37. Epub 2003 Apr 19.PMID: 12704183 [PubMed - indexed for MEDLINE]Related articlesFree article