PubMed

[Improved glucose control and weight loss with exenatide in patients with type 2 diabetes: results of a retrospective observational multicentre Belgian study]

De Block C, Paquot N, Daoudi N, Ballaux D, Van Gaal LF, Scheen AJ.

Rev Med Liege. 2009 Oct;64(10):488-95. French. PMID: 19911661 [PubMed - in process]Related articles

The role of the leptin-melanocortin signalling pathway in the control of food intake.

Beckers S, Zegers D, Van Gaal LF, Van Hul W.

Crit Rev Eukaryot Gene Expr. 2009;19(4):267-87.PMID: 19817705 [PubMed - in process]Related articles

Weight and blood pressure response to weight management and sibutramine in diabetic and non-diabetic high-risk patients: an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes (SCOUT) trial.

Van Gaal LF, Caterson ID, Coutinho W, Finer N, Maggioni AP, Sharma AM, Torp-Pedersen C, Ge H, Moran SA, Shepherd GM, James WP; on behalf of the SCOUT Investigators.

Diabetes Obes Metab. 2009 Sep 16. [Epub ahead of print]PMID: 19758358 [PubMed - as supplied by publisher]Related articles

Association study and mutation analysis of adiponectin shows association of variants in APM1 with complex obesity in women.

Beckers S, Peeters AV, de Freitas F, Mertens IL, Verhulst SL, Haentjens D, Desager KN, Van Gaal LF, Van Hul W.

Ann Hum Genet. 2009 Sep;73(Pt 5):492-501. Epub 2009 Jul 1.PMID: 19573164 [PubMed - in process]Related articles

GLP-1 receptor agonists for type 2 diabetes.

De Block CE, Van Gaal LF.

Lancet. 2009 Jul 4;374(9683):4-6. Epub 2009 Jun 8. Review. No abstract available. PMID: 19515414 [PubMed - indexed for MEDLINE]Related articles

Low fasting triglycerides: hallmark of the healthy large hip?

Ruige JB, Van Gaal LF.

Obesity (Silver Spring). 2009 Aug;17(8):1621-6. Epub 2009 Feb 26.PMID: 19247283 [PubMed - indexed for MEDLINE]Related articles

Association of SIRT1 gene variation with visceral obesity.

Peeters AV, Beckers S, Verrijken A, Mertens I, Roevens P, Peeters PJ, Van Hul W, Van Gaal LF.

Hum Genet. 2008 Nov;124(4):431-6. Epub 2008 Sep 27.PMID: 18820948 [PubMed - indexed for MEDLINE]Related articles

[CB1 receptor inhibition and glucose metabolism: role of rimonabant in type 2 diabetes]

Scheen AJ, Paquot N, Van Gaal LF.

Rev Med Suisse. 2008 Aug 27;4(168):1812-7. Review. French. PMID: 18814765 [PubMed - indexed for MEDLINE]Related articles

Sleep-disordered breathing, obesity, and airway inflammation in children and adolescents.

Verhulst SL, Aerts L, Jacobs S, Schrauwen N, Haentjens D, Claes R, Vaerenberg H, Van Gaal LF, De Backer WA, Desager KN.

Chest. 2008 Dec;134(6):1169-75. Epub 2008 Aug 8.PMID: 18689597 [PubMed - indexed for MEDLINE]Related articles

[Endocannabinoid system in the brain...and elsewhere]

Scheen AJ, Seutin V, Van Gaal LF.

Rev Med Liege. 2008 May-Jun;63(5-6):364-71. French. PMID: 18669206 [PubMed - indexed for MEDLINE]Related articles

[Medication of the month... Exenatide (Byetta) incretinomimetic in the treatment of type 2 diabetes after failure and as add-on therapy to oral agents]

Scheen AJ, Van Gaal LF.

Rev Med Liege. 2008 Mar;63(3):158-65. Review. French. PMID: 18561773 [PubMed - indexed for MEDLINE]Related articles

Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study.

Van Gaal LF, Scheen AJ, Rissanen AM, Rössner S, Hanotin C, Ziegler O; RIO-Europe Study Group.

Eur Heart J. 2008 Jul;29(14):1761-71. Epub 2008 Apr 15.PMID: 18417461 [PubMed - indexed for MEDLINE]Related articlesFree article

[Sitagliptine (Januvia): incretin enhancer potentiating insulin secretion for the treatment of type 2 diabetes]

Scheen AJ, Van Gaal LF.

Rev Med Liege. 2008 Feb;63(2):105-9. French. PMID: 18372550 [PubMed - indexed for MEDLINE]Related articles

Exploiting the antidiabetic properties of incretins to treat type 2 diabetes mellitus: glucagon-like peptide 1 receptor agonists or insulin for patients with inadequate glycemic control?

Van Gaal LF, Gutkin SW, Nauck MA.

Eur J Endocrinol. 2008 Jun;158(6):773-84. Epub 2008 Mar 5. Review.PMID: 18322302 [PubMed - indexed for MEDLINE]Related articlesFree article

[Medication of the month. Rimonabant (Acomplia): first CB1 receptor antagonist of the endocannabinoid system]

Scheen AJ, Van Gaal LF.

Rev Med Liege. 2008 Jan;63(1):50-5. Review. French. PMID: 18303686 [PubMed - indexed for MEDLINE]Related articles

Analysis of genetic variations in the resistin gene shows no associations with obesity in women.

Beckers S, Peeters AV, Freitas F, Mertens IL, Hendrickx JJ, Van Gaal LF, Van Hul W.

Obesity (Silver Spring). 2008 Apr;16(4):905-7. Epub 2008 Jan 24.PMID: 18239575 [PubMed - indexed for MEDLINE]Related articles

Current concepts in gastric motility in diabetes mellitus.

De Block CE, De Leeuw IH, Pelckmans PA, Van Gaal LF.

Curr Diabetes Rev. 2006 Feb;2(1):113-30. Review.PMID: 18220621 [PubMed - indexed for MEDLINE]Related articles

Autoimmune gastritis in type 1 diabetes: a clinically oriented review.

De Block CE, De Leeuw IH, Van Gaal LF.

J Clin Endocrinol Metab. 2008 Feb;93(2):363-71. Epub 2007 Nov 20. Review.PMID: 18029461 [PubMed - indexed for MEDLINE]Related articlesFree article

PAI-1 activity, but not fibrinogen or von Willebrand factor, is inversely related to LDL particle size in type 2 diabetes.

Mertens I, Lemieux I, Verrijken A, Després JP, Van Gaal LF.

Diabetes Metab Res Rev. 2008 Feb;24(2):141-7.PMID: 17922472 [PubMed - indexed for MEDLINE]Related articles

The safety of obesity drugs.

Van Gaal LF, Scheen AJ, Formiguera X.

Expert Opin Drug Saf. 2007 Sep;6(5):475-6; author reply 477-8. No abstract available. PMID: 17877434 [PubMed - indexed for MEDLINE]Related articles

Rimonabant as an adjunct therapy in overweight/obese patients with type 2 diabetes.

Scheen AJ, Van Gaal LF.

Eur Heart J. 2007 Jun;28(11):1401-2; author reply 1402. Epub 2007 May 10. No abstract available. PMID: 17493946 [PubMed - indexed for MEDLINE]Related articlesFree article

[Cardiometabolic effects of rimonabant in obese/overweight subjects with dyslipidaemia or type 2 diabetes]

Scheen AJ, Van Gaal LF.

Rev Med Liege. 2007 Feb;62(2):81-5. French. PMID: 17461296 [PubMed - indexed for MEDLINE]Related articles

Mechanisms linking obesity with cardiovascular disease.

Van Gaal LF, Mertens IL, De Block CE.

Nature. 2006 Dec 14;444(7121):875-80. Review.PMID: 17167476 [PubMed - indexed for MEDLINE]Related articles

Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study.

Scheen AJ, Finer N, Hollander P, Jensen MD, Van Gaal LF; RIO-Diabetes Study Group.

Lancet. 2006 Nov 11;368(9548):1660-72. Erratum in: Lancet. 2006 Nov 11;368(9548):1650. PMID: 17098084 [PubMed - indexed for MEDLINE]Related articles

Hemostasis and fibrinolysis in non-diabetic overweight and obese men and women. Is there still a role for leptin?

Mertens I, Considine RV, Van der Planken M, Van Gaal LF.

Eur J Endocrinol. 2006 Sep;155(3):477-84.PMID: 16914603 [PubMed - indexed for MEDLINE]Related articlesFree article

Fasting-based estimates of insulin sensitivity in overweight and obesity: a critical appraisal.

Ruige JB, Mertens IL, Bartholomeeusen E, Dirinck E, Ferrannini E, Van Gaal LF.

Obesity (Silver Spring). 2006 Jul;14(7):1250-6.PMID: 16899806 [PubMed - indexed for MEDLINE]Related articles

Long-term health considerations in schizophrenia: metabolic effects and the role of abdominal adiposity.

Van Gaal LF.

Eur Neuropsychopharmacol. 2006 Sep;16 Suppl 3:S142-8. Epub 2006 Jul 24. Review.PMID: 16863690 [PubMed - indexed for MEDLINE]Related articles

New approaches for the management of patients with multiple cardiometabolic risk factors.

Van Gaal LF, Peiffer F.

J Endocrinol Invest. 2006;29(3 Suppl):83-9. Review.PMID: 16751712 [PubMed - indexed for MEDLINE]Related articles

New International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment panel III (NCEP-ATPIII) criteria and the involvement of hemostasis and fibrinolysis in the metabolic syndrome.

Mertens I, Van Gaal LF.

J Thromb Haemost. 2006 May;4(5):1164-6. No abstract available. PMID: 16689783 [PubMed - indexed for MEDLINE]Related articles

Is visceral adipose tissue a determinant of von Willebrand factor in overweight and obese premenopausal women?

Mertens I, Van der Planken M, Corthouts B, Van Gaal LF.

Metabolism. 2006 May;55(5):650-5.PMID: 16631442 [PubMed - indexed for MEDLINE]Related articles

Inverse relationship between plasminogen activator inhibitor-I activity and adiponectin in overweight and obese women. Interrelationship with visceral adipose tissue, insulin resistance, HDL-chol and inflammation.

Mertens I, Ballaux D, Funahashi T, Matsuzawa Y, Van der Planken M, Verrijken A, Ruige JB, Van Gaal LF.

Thromb Haemost. 2005 Dec;94(6):1190-5.PMID: 16411393 [PubMed - indexed for MEDLINE]Related articles

Among inflammation and coagulation markers, PAI-1 is a true component of the metabolic syndrome.

Mertens I, Verrijken A, Michiels JJ, Van der Planken M, Ruige JB, Van Gaal LF.

Int J Obes (Lond). 2006 Aug;30(8):1308-14. Epub 2006 Jan 3.PMID: 16389265 [PubMed - indexed for MEDLINE]Related articles

Time course of oxidative stress status in the postprandial and postabsorptive states in type 1 diabetes mellitus: relationship to glucose and lipid changes.

Manuel-y-Keenoy B, Van Campenhout A, Aerts P, Vertommen J, Abrams P, Van Gaal LF, Van Gils C, De Leeuw IH.

J Am Coll Nutr. 2005 Dec;24(6):474-85.PMID: 16373944 [PubMed - indexed for MEDLINE]Related articlesFree article

Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.

Heine RJ, Van Gaal LF, Johns D, Mihm MJ, Widel MH, Brodows RG; GWAA Study Group.

Ann Intern Med. 2005 Oct 18;143(8):559-69.PMID: 16230722 [PubMed - indexed for MEDLINE]Related articlesFree article

[In Process Citation]

Van Gaal LF, Scheen AJ.

Int J Obes (Lond). 2000 May;24 Suppl 1:S1. No abstract available. PMID: 16205659 [PubMed - as supplied by publisher]Free article

Opposite effects of insulin-like molecules and leptin in coronary heart disease of type 2 diabetes Preliminary data.

Ruige JB, Mertens I, Considine RV, Paelinck BP, Van Gaal LF.

Int J Cardiol. 2006 Jul 28;111(1):19-25. Epub 2005 Jul 20.PMID: 16038995 [PubMed - indexed for MEDLINE]Related articles

[Type 2 diabetes, in the heart of the metabolic syndrome: plea for a global approach]

Scheen AJ, Van Gaal LF.

Rev Med Liege. 2005 May-Jun;60(5-6):566-71. Review. French. PMID: 16035330 [PubMed - indexed for MEDLINE]Related articles

[The cost of type 2 diabetes: summary of the Cost of Diabetes in Europe-Type II study (CODE-2) and analysis of the situation in Belgium]

Wallemacq C, Van Gaal LF, Scheen AJ.

Rev Med Liege. 2005 May-Jun;60(5-6):278-84. French. PMID: 16035280 [PubMed - indexed for MEDLINE]Related articles

Resting metabolic rate is an important predictor of serum adiponectin concentrations: potential implications for obesity-related disorders.

Ruige JB, Ballaux DP, Funahashi T, Mertens IL, Matsuzawa Y, Van Gaal LF.

Am J Clin Nutr. 2005 Jul;82(1):21-5.PMID: 16002795 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of overweight on chronic microvascular complications in type 1 diabetic patients.

De Block CE, De Leeuw IH, Van Gaal LF.

Diabetes Care. 2005 Jul;28(7):1649-55.PMID: 15983315 [PubMed - indexed for MEDLINE]Related articlesFree article

Visceral fat as a determinant of fibrinolysis and hemostasis.

Mertens I, Van Gaal LF.

Semin Vasc Med. 2005 Feb;5(1):48-55. Review.PMID: 15968580 [PubMed - indexed for MEDLINE]Related articles

Obesity, health issues, and cardiovascular disease.

Van Gaal LF, Michiels JJ.

Semin Vasc Med. 2005 Feb;5(1):1-2. No abstract available. PMID: 15968574 [PubMed - indexed for MEDLINE]Related articles

Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study.

Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rössner S; RIO-Europe Study Group.

Lancet. 2005 Apr 16-22;365(9468):1389-97. Erratum in: Lancet. 2005 Jul 30-Aug 5;366(9483):370. PMID: 15836887 [PubMed - indexed for MEDLINE]Related articles

Initiating oral glucose-lowering therapy with metformin in type 2 diabetic patients: an evidence-based strategy to reduce the burden of late-developing diabetes complications.

Consoli A, Gomis R, Halimi S, Home PD, Mehnert H, Strojek K, Van Gaal LF.

Diabetes Metab. 2004 Dec;30(6):509-16. Review.PMID: 15671920 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroendocrine tumor markers and enterochromaffin-like cell hyper/dysplasia in type 1 diabetes.

De Block CE, Colpin G, Thielemans K, Coopmans W, Bogers JJ, Pelckmans PA, Van Marck EA, Van Hoof V, Martin M, De Leeuw IH, Bouillon R, Van Gaal LF.

Diabetes Care. 2004 Jun;27(6):1387-93.PMID: 15161793 [PubMed - indexed for MEDLINE]Related articlesFree article

Health risks of lipodystrophy and abdominal fat accumulation: therapeutic possibilities with leptin and human growth hormone.

Van Gaal LF, Mertens IL, Abrams PJ.

Growth Horm IGF Res. 2003 Aug;13 Suppl A:S4-9. Review.PMID: 12914718 [PubMed - indexed for MEDLINE]Related articles

Leisure-time activity is an important determinant of long-term weight maintenance after weight loss in the Sibutramine Trial on Obesity Reduction and Maintenance (STORM trial).

van Baak MA, van Mil E, Astrup AV, Finer N, Van Gaal LF, Hilsted J, Kopelman PG, Rössner S, James WP, Saris WH; STORM Study Group.

Am J Clin Nutr. 2003 Aug;78(2):209-14.PMID: 12885699 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion.

Wauters M, Considine RV, Yudkin JS, Peiffer F, De Leeuw I, Van Gaal LF.

Horm Metab Res. 2003 Feb;35(2):92-6.PMID: 12734788 [PubMed - indexed for MEDLINE]Related articles

Addition of rosiglitazone to metformin is most effective in obese, insulin-resistant patients with type 2 diabetes.

Jones TA, Sautter M, Van Gaal LF, Jones NP.

Diabetes Obes Metab. 2003 May;5(3):163-70.PMID: 12681023 [PubMed - indexed for MEDLINE]Related articles

Rationale and options for combination therapy in the treatment of Type 2 diabetes.

Van Gaal LF, De Leeuw IH.

Diabetologia. 2003 Mar;46 Suppl 1:M44-50. Epub 2003 Feb 5. Review.PMID: 12652358 [PubMed - indexed for MEDLINE]Related articles