PubMed

Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity.

Ionova-Martin SS, Do SH, Barth HD, Szadkowska M, Porter AE, Ager JW 3rd, Ager JW Jr, Alliston T, Vaisse C, Ritchie RO.

Bone. 2009 Oct 21. [Epub ahead of print]PMID: 19853069 [PubMed - as supplied by publisher]Related articles

In silico mutagenesis: a case study of the melanocortin 4 receptor.

Bromberg Y, Overton J, Vaisse C, Leibel RL, Rost B.

FASEB J. 2009 Sep;23(9):3059-69. Epub 2009 May 5.PMID: 19417090 [PubMed - indexed for MEDLINE]Related articlesFree article

Narrowing down the role of common variants in the genetic predisposition to obesity.

Calton MA, Vaisse C.

Genome Med. 2009 Mar 11;1(3):31. [Epub ahead of print]PMID: 19341502 [PubMed - as supplied by publisher]Related articlesFree article

Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.

Ranadive SA, Ersoy B, Favre H, Cheung CC, Rosenthal SM, Miller WL, Vaisse C.

Clin Endocrinol (Oxf). 2009 Sep;71(3):388-93. Epub 2008 Dec 18.PMID: 19170711 [PubMed - indexed for MEDLINE]Related articles

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.

Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C.

Hum Mol Genet. 2009 Mar 15;18(6):1140-7. Epub 2008 Dec 17.PMID: 19091795 [PubMed - indexed for MEDLINE]Related articles

Lessons from extreme human obesity: monogenic disorders.

Ranadive SA, Vaisse C.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):733-51, x. Review.PMID: 18775361 [PubMed - indexed for MEDLINE]Related articles

Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene.

Clément K, Dubern B, Mencarelli M, Czernichow P, Ito S, Wakamatsu K, Barsh GS, Vaisse C, Leger J.

J Clin Endocrinol Metab. 2008 Dec;93(12):4955-62. Epub 2008 Sep 2.PMID: 18765507 [PubMed - indexed for MEDLINE]Related articles

Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes.

Louet JF, Smith SB, Gautier JF, Molokhia M, Virally ML, Kevorkian JP, Guillausseau PJ, Vexiau P, Charpentier G, German MS, Vaisse C, Urbanek M, Mauvais-Jarvis F.

Diabetes Obes Metab. 2008 Sep;10(10):912-20. Epub 2007 Dec 17.PMID: 18093211 [PubMed - indexed for MEDLINE]Related articles

Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain.

Dubern B, Lubrano-Berthelier C, Mencarelli M, Ersoy B, Frelut ML, Bouglé D, Costes B, Simon C, Tounian P, Vaisse C, Clement K.

Pediatr Res. 2008 Feb;63(2):211-6.PMID: 18091355 [PubMed - indexed for MEDLINE]Related articles

Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo.

Srinivasan S, Santiago P, Lubrano C, Vaisse C, Conklin BR.

PLoS One. 2007 Aug 1;2(7):e668.PMID: 17668051 [PubMed]Related articlesFree article

Medical sequencing at the extremes of human body mass.

Ahituv N, Kavaslar N, Schackwitz W, Ustaszewska A, Martin J, Hebert S, Doelle H, Ersoy B, Kryukov G, Schmidt S, Yosef N, Ruppin E, Sharan R, Vaisse C, Sunyaev S, Dent R, Cohen J, McPherson R, Pennacchio LA.

Am J Hum Genet. 2007 Apr;80(4):779-91. Epub 2007 Mar 5.PMID: 17357083 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating.

Lubrano-Berthelier C, Dubern B, Lacorte JM, Picard F, Shapiro A, Zhang S, Bertrais S, Hercberg S, Basdevant A, Clement K, Vaisse C.

J Clin Endocrinol Metab. 2006 May;91(5):1811-8. Epub 2006 Feb 28.PMID: 16507637 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of support for the association between GAD2 polymorphisms and severe human obesity.

Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane JP, Dent R, McPherson R, Kwok PY, Hinney A, Hebebrand J, Vaisse C.

PLoS Biol. 2005 Sep;3(9):e315. Epub 2005 Aug 30.PMID: 16122350 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function.

Govaerts C, Srinivasan S, Shapiro A, Zhang S, Picard F, Clement K, Lubrano-Berthelier C, Vaisse C.

Peptides. 2005 Oct;26(10):1909-19. Review.PMID: 16083993 [PubMed - indexed for MEDLINE]Related articles

High prevalence of glucose-6-phosphate dehydrogenase deficiency without gene mutation suggests a novel genetic mechanism predisposing to ketosis-prone diabetes.

Sobngwi E, Gautier JF, Kevorkian JP, Villette JM, Riveline JP, Zhang S, Vexiau P, Leal SM, Vaisse C, Mauvais-Jarvis F.

J Clin Endocrinol Metab. 2005 Aug;90(8):4446-51. Epub 2005 May 24.PMID: 15914531 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin regulation of bone resorption by the sympathetic nervous system and CART.

Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G.

Nature. 2005 Mar 24;434(7032):514-20. Epub 2005 Feb 20.PMID: 15724149 [PubMed - indexed for MEDLINE]Related articles

A statistical approach for array CGH data analysis.

Picard F, Robin S, Lavielle M, Vaisse C, Daudin JJ.

BMC Bioinformatics. 2005 Feb 11;6:27.PMID: 15705208 [PubMed - indexed for MEDLINE]Related articlesFree article

PAX4 gene variations predispose to ketosis-prone diabetes.

Mauvais-Jarvis F, Smith SB, Le May C, Leal SM, Gautier JF, Molokhia M, Riveline JP, Rajan AS, Kevorkian JP, Zhang S, Vexiau P, German MS, Vaisse C.

Hum Mol Genet. 2004 Dec 15;13(24):3151-9. Epub 2004 Oct 27.PMID: 15509590 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.

Srinivasan S, Lubrano-Berthelier C, Govaerts C, Picard F, Santiago P, Conklin BR, Vaisse C.

J Clin Invest. 2004 Oct;114(8):1158-64.PMID: 15489963 [PubMed - indexed for MEDLINE]Related articlesFree article

A homozygous null mutation delineates the role of the melanocortin-4 receptor in humans.

Lubrano-Berthelier C, Le Stunff C, Bougnères P, Vaisse C.

J Clin Endocrinol Metab. 2004 May;89(5):2028-32.PMID: 15126516 [PubMed - indexed for MEDLINE]Related articlesFree article

Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance.

Mauvais-Jarvis F, Sobngwi E, Porcher R, Riveline JP, Kevorkian JP, Vaisse C, Charpentier G, Guillausseau PJ, Vexiau P, Gautier JF.

Diabetes. 2004 Mar;53(3):645-53.PMID: 14988248 [PubMed - indexed for MEDLINE]Related articlesFree article

The human MC4R promoter: characterization and role in obesity.

Lubrano-Berthelier C, Cavazos M, Le Stunff C, Haas K, Shapiro A, Zhang S, Bougneres P, Vaisse C.

Diabetes. 2003 Dec;52(12):2996-3000.PMID: 14633862 [PubMed - indexed for MEDLINE]Related articlesFree article

Engineering the melanocortin-4 receptor to control G(s) signaling in vivo.

Srinivasan S, Vaisse C, Conklin BR.

Ann N Y Acad Sci. 2003 Jun;994:225-32. Review.PMID: 12851320 [PubMed - indexed for MEDLINE]Related articles

Molecular genetics of human obesity-associated MC4R mutations.

Lubrano-Berthelier C, Cavazos M, Dubern B, Shapiro A, Stunff CL, Zhang S, Picart F, Govaerts C, Froguel P, Bougneres P, Clement K, Vaisse C.

Ann N Y Acad Sci. 2003 Jun;994:49-57. Review.PMID: 12851297 [PubMed - indexed for MEDLINE]Related articles

Emerging trends in the search for genetic variants predisposing to human obesity.

Swarbrick MM, Vaisse C.

Curr Opin Clin Nutr Metab Care. 2003 Jul;6(4):369-75. Review.PMID: 12806208 [PubMed - indexed for MEDLINE]Related articles

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations.

Lubrano-Berthelier C, Durand E, Dubern B, Shapiro A, Dazin P, Weill J, Ferron C, Froguel P, Vaisse C.

Hum Mol Genet. 2003 Jan 15;12(2):145-53.PMID: 12499395 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated plasma ghrelin levels in Prader Willi syndrome.

Cummings DE, Clement K, Purnell JQ, Vaisse C, Foster KE, Frayo RS, Schwartz MW, Basdevant A, Weigle DS.

Nat Med. 2002 Jul;8(7):643-4. No abstract available. PMID: 12091883 [PubMed - indexed for MEDLINE]Related articles

Glycodelin: a pane in the implantation window.

Mueller MD, Vigne JL, Vaisse C, Taylor RN.

Semin Reprod Med. 2000;18(3):289-98.PMID: 11299967 [PubMed - indexed for MEDLINE]Related articles

Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass.

Lahlou N, Clement K, Carel JC, Vaisse C, Lotton C, Le Bihan Y, Basdevant A, Lebouc Y, Froguel P, Roger M, Guy-Grand B.

Diabetes. 2000 Aug;49(8):1347-52.PMID: 10923636 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity.

Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P.

J Clin Invest. 2000 Jul;106(2):253-62.PMID: 10903341 [PubMed - indexed for MEDLINE]Related articlesFree article

The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.

Navas MA, Vaisse C, Boger S, Heimesaat M, Kollee LA, Stoffel M.

Hum Hered. 2000 Nov-Dec;50(6):370-81.PMID: 10899756 [PubMed - indexed for MEDLINE]Related articlesFree article

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes.

Clement K, Hercberg S, Passinge B, Galan P, Varroud-Vial M, Shuldiner AR, Beamer BA, Charpentier G, Guy-Grand B, Froguel P, Vaisse C.

Int J Obes Relat Metab Disord. 2000 Mar;24(3):391-3.PMID: 10757637 [PubMed - indexed for MEDLINE]Related articles

Promegestone (R5020) and mifepristone (RU486) both function as progestational agonists of human glycodelin gene expression in isolated human epithelial cells.

Taylor RN, Savouret JF, Vaisse C, Vigne JL, Ryan I, Hornung D, Seppälä M, Milgrom E.

J Clin Endocrinol Metab. 1998 Nov;83(11):4006-12.PMID: 9814484 [PubMed - indexed for MEDLINE]Related articlesFree article

A frameshift mutation in human MC4R is associated with a dominant form of obesity.

Vaisse C, Clement K, Guy-Grand B, Froguel P.

Nat Genet. 1998 Oct;20(2):113-4. No abstract available. PMID: 9771699 [PubMed - indexed for MEDLINE]Related articles

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.

Clément K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D, Gourmelen M, Dina C, Chambaz J, Lacorte JM, Basdevant A, Bougnères P, Lebouc Y, Froguel P, Guy-Grand B.

Nature. 1998 Mar 26;392(6674):398-401.PMID: 9537324 [PubMed - indexed for MEDLINE]Related articles

Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6.

Vaisse C, Kim J, Espinosa R 3rd, Le Beau MM, Stoffel M.

Diabetes. 1997 Aug;46(8):1364-7.PMID: 9231664 [PubMed - indexed for MEDLINE]Related articles

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice.

Vaisse C, Halaas JL, Horvath CM, Darnell JE Jr, Stoffel M, Friedman JM.

Nat Genet. 1996 Sep;14(1):95-7.PMID: 8782827 [PubMed - indexed for MEDLINE]Related articles

Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.

Ruiz J, Blanché H, James RW, Garin MC, Vaisse C, Charpentier G, Cohen N, Morabia A, Passa P, Froguel P.

Lancet. 1995 Sep 30;346(8979):869-72.PMID: 7564671 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity.

Clément K, Vaisse C, Manning BS, Basdevant A, Guy-Grand B, Ruiz J, Silver KD, Shuldiner AR, Froguel P, Strosberg AD.

N Engl J Med. 1995 Aug 10;333(6):352-4.PMID: 7609752 [PubMed - indexed for MEDLINE]Related articlesFree article

A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus.

Hager J, Hansen L, Vaisse C, Vionnet N, Philippi A, Poller W, Velho G, Carcassi C, Contu L, Julier C, et al.

Nat Genet. 1995 Mar;9(3):299-304.PMID: 7773293 [PubMed - indexed for MEDLINE]Related articles

Expression and regulation of adrenodoxin and P450scc mRNA in rodent tissues.

Mellon SH, Kushner JA, Vaisse C.

DNA Cell Biol. 1991 Jun;10(5):339-47.PMID: 1863358 [PubMed - indexed for MEDLINE]Related articles

The human placental protein 14 (PP14) gene is localized on chromosome 9q34.

Van Cong N, Vaisse C, Gross MS, Slim R, Milgrom E, Bernheim A.

Hum Genet. 1991 Mar;86(5):515-8.PMID: 2016092 [PubMed - indexed for MEDLINE]Related articles

Human placental protein 14 gene: sequence and characterization of a short duplication.

Vaisse C, Atger M, Potier B, Milgrom E.

DNA Cell Biol. 1990 Jul-Aug;9(6):401-13.PMID: 2206398 [PubMed - indexed for MEDLINE]Related articles

cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cells.

Mellon SH, Vaisse C.

Proc Natl Acad Sci U S A. 1989 Oct;86(20):7775-9.PMID: 2554289 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pyodermatitis of the nasal pyramid disclosing a complication of rhinoplasty with silicone implant]

Berbis P, Lebeuf C, Vaisse C, Zanaret M, Privat Y.

Ann Dermatol Venereol. 1989;116(3):233-5. French. No abstract available. PMID: 2742302 [PubMed - indexed for MEDLINE]Related articles

Benefit of progressively increasing doses during the initial treatment with acitretin in psoriasis.

Berbis P, Geiger JM, Vaisse C, Rognin C, Privat Y.

Dermatologica. 1989;178(2):88-92.PMID: 2522405 [PubMed - indexed for MEDLINE]Related articles