PubMed

An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma.

Vij R, Horvath N, Spencer A, Taylor K, Vadhan-Raj S, Vescio R, Smith J, Qian Y, Yeh H, Jun S.

Am J Hematol. 2009 Oct;84(10):650-6.PMID: 19714603 [PubMed - in process]Related articles

Cuplike nuclei (prominent nuclear invaginations) in acute myeloid leukemia are highly associated with FLT3 internal tandem duplication and NPM1 mutation.

Chen W, Konoplev S, Medeiros LJ, Koeppen H, Leventaki V, Vadhan-Raj S, Jones D, Kantarjian HM, Falini B, Bueso-Ramos CE.

Cancer. 2009 Dec 1;115(23):5481-9.PMID: 19672946 [PubMed - in process]Related articles

Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia.

Ye D, Garcia-Manero G, Kantarjian HM, Xiao L, Vadhan-Raj S, Fernandez MH, Nguyen MH, Medeiros LJ, Bueso-Ramos CE.

J Hematop. 2009 Mar;2(1):2-8. Epub 2008 Nov 4.PMID: 19669217 [PubMed - in process]Related articlesFree article

Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents.

Vadhan-Raj S.

Semin Hematol. 2009 Jan;46(1 Suppl 2):S26-32. Review.PMID: 19245931 [PubMed - indexed for MEDLINE]Related articles

A phase II study of GM-CSF and rIFN-gamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer.

Schmeler KM, Vadhan-Raj S, Ramirez PT, Apte SM, Cohen L, Bassett RL, Iyer RB, Wolf JK, Levenback CL, Gershenson DM, Freedman RS.

Gynecol Oncol. 2009 May;113(2):210-5. Epub 2009 Mar 4.PMID: 19264351 [PubMed - indexed for MEDLINE]Related articles

Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer.

Park HC, Janjan NA, Mendoza TR, Lin EH, Vadhan-Raj S, Hundal M, Zhang Y, Delclos ME, Crane CH, Das P, Wang XS, Cleeland CS, Krishnan S.

Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):775-81. Epub 2009 Feb 21.PMID: 19231100 [PubMed - indexed for MEDLINE]Related articles

Myeloid growth factors.

Crawford J, Armitage J, Balducci L, Bennett C, Blayney DW, Cataland SR, Dale DC, Demetri GD, Erba HP, Foran J, Freifeld AG, Goemann M, Heaney ML, Htoy S, Hudock S, Kloth DD, Kuter DJ, Lyman GH, Michaud LB, Miyata SC, Tallman MS, Vadhan-Raj S, Westervelt P, Wong MK; National Comprehensive Cancer Network.

J Natl Compr Canc Netw. 2009 Jan;7(1):64-83. No abstract available. PMID: 19176207 [PubMed - indexed for MEDLINE]Related articles

Development of a fatigue and functional impact scale in anemic cancer patients receiving chemotherapy.

Cella D, Viswanathan HN, Hays RD, Mendoza TR, Stein KD, Pasta DJ, Foreman AJ, Vadhan-Raj S, Kallich JD.

Cancer. 2008 Sep 15;113(6):1480-8.PMID: 18642348 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative analysis of genes regulated in acute myelomonocytic leukemia with and without inv(16)(p13q22) using microarray techniques, real-time PCR, immunohistochemistry, and flow cytometry immunophenotyping.

Sun X, Zhang W, Ramdas L, Stivers DN, Jones DM, Kantarjian HM, Estey EH, Vadhan-Raj S, Medeiros LJ, Bueso-Ramos CE.

Mod Pathol. 2007 Aug;20(8):811-20. Epub 2007 Jun 15.PMID: 17571080 [PubMed - indexed for MEDLINE]Related articlesFree article

Myeloid growth factors. Clinical practice guidelines in oncology.

Crawford J, Althaus B, Armitage J, Balducci L, Bennett C, Blayney DW, Cataland SR, Dale DC, Demetri GD, Erba HP, Foran J, Freifeld AG, Heaney ML, Htoy S, Kloth DD, Lyman GH, Messersmith WA, Michaud LB, Miyata SC, Robbins A, Tallman MS, Vadhan-Raj S, Westervelt P, Wong MK; National Comprehensive Cancer Network (NCCN).

J Natl Compr Canc Netw. 2007 Feb;5(2):188-202. No abstract available. PMID: 17335688 [PubMed - indexed for MEDLINE]Related articles

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S, Aggarwal BB.

Blood. 2007 Mar 15;109(6):2293-302. Epub 2006 Dec 12.PMID: 17164350 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).

Zhao W, Claxton DF, Medeiros LJ, Lu D, Vadhan-Raj S, Kantarjian HM, Nguyen MH, Bueso-Ramos CE.

Am J Surg Pathol. 2006 Nov;30(11):1436-44.PMID: 17063086 [PubMed - indexed for MEDLINE]Related articles

Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer.

Krishnan S, Janjan NA, Skibber JM, Rodriguez-Bigas MA, Wolff RA, Das P, Delclos ME, Chang GJ, Hoff PM, Eng C, Brown TD, Crane CH, Feig BW, Morris J, Vadhan-Raj S, Hamilton SR, Lin EH.

Int J Radiat Oncol Biol Phys. 2006 Nov 1;66(3):762-71.PMID: 17011451 [PubMed - indexed for MEDLINE]Related articles

Primary plasma cell leukemia: morphologic, immunophenotypic, and cytogenetic features of 4 cases treated with chemotherapy and stem cell transplantation.

Johnson MR, Del Carpio-Jayo D, Lin P, Giralt S, Anderlini P, Champlin RE, Khouri IF, Vadhan-Raj S, Medeiros LJ, Bueso-Ramos CE.

Ann Diagn Pathol. 2006 Oct;10(5):263-8.PMID: 16979517 [PubMed - indexed for MEDLINE]Related articles

Randomized comparison of every-2-week darbepoetin alfa and weekly epoetin alfa for the treatment of chemotherapy-induced anemia: the 20030125 Study Group Trial.

20030125 Study Group Trial, Glaspy J, Vadhan-Raj S, Patel R, Bosserman L, Hu E, Lloyd RE, Boccia RV, Tomita D, Rossi G.

J Clin Oncol. 2006 May 20;24(15):2290-7.PMID: 16710026 [PubMed - indexed for MEDLINE]Related articles

Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia and does not correlate with p65 NF-kappaB activation.

Merzianu M, Jiang L, Lin P, Wang X, Weber DM, Vadhan-Raj S, Nguyen MH, Medeiros LJ, Bueso-Ramos CE.

Mod Pathol. 2006 Jul;19(7):891-8. Epub 2006 Apr 21.PMID: 16636680 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines, GM-CSF and IFNgamma administered by priming and post-chemotherapy cycling in recurrent ovarian cancer patients receiving carboplatin.

Apte SM, Vadhan-Raj S, Cohen L, Bassett RL, Gordon IO, Levenback CF, Ramirez PT, Gallardo ST, Patenia RS, Garcia ME, Iyer RB, Freedman RS.

J Transl Med. 2006 Apr 7;4:16.PMID: 16603073 [PubMed]Related articlesFree article

Aerosolized ribavirin-induced reversible hepatotoxicity in a hematopoietic stem cell transplant recipient with Hodgkin lymphoma.

Chaves J, Huen A, Bueso-Ramos C, Safdar A, Vadhan-Raj S.

Clin Infect Dis. 2006 Apr 15;42(8):e72-5. Epub 2006 Mar 13. Erratum in: Clin Infect Dis. 2006 May 15;42(10):1512. PMID: 16575720 [PubMed - indexed for MEDLINE]Related articles

Myeloid growth factors clinical practice guidelines in oncology.

Crawford J, Althaus B, Armitage J, Blayney DW, Cataland S, Dale DC, Demetri GD, Foran J, Heaney ML, Htoy S, Kloth DD, Lyman GH, Michaud L, Motl S, Vadhan-Raj S, Wong MK; National Comprehensive Cancer Network.

J Natl Compr Canc Netw. 2005 Jul;3(4):540-55. No abstract available. PMID: 16038645 [PubMed - indexed for MEDLINE]Related articles

Thrombopoietic growth factors and cytokines.

Vadhan-Raj S, Cohen V, Bueso-Ramos C.

Curr Hematol Rep. 2005 Mar;4(2):137-44.PMID: 15720963 [PubMed - indexed for MEDLINE]Related articles

Assessment of hematologic effects and fatigue in cancer patients with chemotherapy-induced anemia given darbepoetin alfa every two weeks.

Vadhan-Raj S, Mirtsching B, Charu V, Terry D, Rossi G, Tomita D, McGuire WP.

J Support Oncol. 2003 Jul-Aug;1(2):131-8.PMID: 15352656 [PubMed - indexed for MEDLINE]Related articles

Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia.

Bueso-Ramos CE, Rocha FC, Shishodia S, Medeiros LJ, Kantarjian HM, Vadhan-Raj S, Estrov Z, Smith TL, Nguyen MH, Aggarwal BB.

Hum Pathol. 2004 Feb;35(2):246-53.PMID: 14991544 [PubMed - indexed for MEDLINE]Related articles

Pilot study of Flt3 ligand comparing intraperitoneal with subcutaneous routes on hematologic and immunologic responses in patients with peritoneal carcinomatosis and mesotheliomas.

Freedman RS, Vadhan-Raj S, Butts C, Savary C, Melichar B, Verschraegen C, Kavanagh JJ, Hicks ME, Levy LB, Folloder JK, Garcia ME.

Clin Cancer Res. 2003 Nov 1;9(14):5228-37.PMID: 14614003 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of predosing of recombinant human thrombopoietin to reduce chemotherapy-induced early thrombocytopenia.

Vadhan-Raj S, Patel S, Bueso-Ramos C, Folloder J, Papadopolous N, Burgess A, Broemeling LD, Broxmeyer HE, Benjamin RS.

J Clin Oncol. 2003 Aug 15;21(16):3158-67.PMID: 12915607 [PubMed - indexed for MEDLINE]Related articles

Cost of chemotherapy-induced thrombocytopenia among patients with lymphoma or solid tumors.

Elting LS, Cantor SB, Martin CG, Hamblin L, Kurtin D, Rivera E, Vadhan-Raj S, Benjamin RS.

Cancer. 2003 Mar 15;97(6):1541-50.PMID: 12627519 [PubMed - indexed for MEDLINE]Related articlesFree article

Future directions with hematopoietic growth factors.

Vadhan-Raj S.

J Natl Compr Canc Netw. 2003 Jan;1 Suppl 1:S96-101. Review.PMID: 19795582 [PubMed - indexed for MEDLINE]Related articles

Every-2-week darbepoetin alfa is comparable to rHuEPO in treating chemotherapy-induced anemia. Results of a combined analysis.

Mirtsching B, Charu V, Vadhan-Raj S, Colowick AB, Rossi G, Tomita D, McGuire WP.

Oncology (Williston Park). 2002 Oct;16(10 Suppl 11):31-6.PMID: 12435171 [PubMed - indexed for MEDLINE]Related articles

The Bleeding Risk Index: a clinical prediction rule to guide the prophylactic use of platelet transfusions in patients with lymphoma or solid tumors.

Elting LS, Martin CG, Kurtin DJ, Cantor SB, Rubenstein EB, Rodriguez S, Kanesan K, Vadhan-Raj S, Benjamin RS.

Cancer. 2002 Jun 15;94(12):3252-62.PMID: 12115358 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety and efficacy of transfusions of autologous cryopreserved platelets derived from recombinant human thrombopoietin to support chemotherapy-associated severe thrombocytopenia: a randomised cross-over study.

Vadhan-Raj S, Kavanagh JJ, Freedman RS, Folloder J, Currie LM, Bueso-Ramos C, Verschraegen CF, Narvios AB, Connor J, Hoots WK, Broemeling LD, Lichtiger B.

Lancet. 2002 Jun 22;359(9324):2145-52.PMID: 12090979 [PubMed - indexed for MEDLINE]Related articles

Recombinant human thrombopoietin in myelosuppressive chemotherapy.

Vadhan-Raj S.

Oncology (Williston Park). 2001 Jul;15(7 Suppl 8):35-8.PMID: 11497230 [PubMed - indexed for MEDLINE]Related articles

Dendritic cell-mediated stimulation of the in vitro lymphocyte response to Aspergillus.

Grazziutti M, Przepiorka D, Rex JH, Braunschweig I, Vadhan-Raj S, Savary CA.

Bone Marrow Transplant. 2001 Mar;27(6):647-52.PMID: 11319596 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant human thrombopoietin clinical development.

Jones DV Jr, Ashby M, Vadhan-Raj S, Somlo G, Champlin R, Gajewski J, Hellmann S, Fyfe G.

Stem Cells. 1998;16 Suppl 2:199-206.PMID: 11012192 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical experience with recombinant human thrombopoietin in chemotherapy-induced thrombocytopenia.

Vadhan-Raj S.

Semin Hematol. 2000 Apr;37(2 Suppl 4):28-34. Review.PMID: 10831286 [PubMed - indexed for MEDLINE]Related articles

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer.

Vadhan-Raj S, Verschraegen CF, Bueso-Ramos C, Broxmeyer HE, Kudelkà AP, Freedman RS, Edwards CL, Gershenson D, Jones D, Ashby M, Kavanagh JJ.

Ann Intern Med. 2000 Mar 7;132(5):364-8.PMID: 10691586 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced retention of in vitro functional activity of platelets from recombinant human thrombopoietin-treated patients following long-term cryopreservation with a platelet-preserving solution (ThromboSol) and 2% DMSO.

Vadhan-Raj S, Currie LM, Bueso-Ramos C, Livesey SA, Connor J.

Br J Haematol. 1999 Feb;104(2):403-11.PMID: 10050726 [PubMed - indexed for MEDLINE]Related articles

Docetaxel and cyclophosphamide induced remission in platinum and paclitaxel refractory ovarian cancer.

Benjapibal M, Kudelka AP, Vasuratna A, Edwards CL, Verschraegen CF, Valero V, Vadhan-Raj S, Kavanagh JJ.

Anticancer Drugs. 1998 Jul;9(6):577-9.PMID: 9877247 [PubMed - indexed for MEDLINE]Related articles

Thrombopoietin: biology and potential clinical applications.

Prow D, Vadhan-Raj S.

Oncology (Williston Park). 1998 Nov;12(11):1597-604, 1607-8; discussion 1611-4. Review.PMID: 9834938 [PubMed - indexed for MEDLINE]Related articles

Recombinant human thrombopoietin: clinical experience and in vivo biology.

Vadhan-Raj S.

Semin Hematol. 1998 Jul;35(3):261-8. Review.PMID: 9685172 [PubMed - indexed for MEDLINE]Related articles

Results of two consecutive trials of dose-intensive chemotherapy with doxorubicin and ifosfamide in patients with sarcomas.

Patel SR, Vadhan-Raj S, Burgess MA, Plager C, Papadopolous N, Jenkins J, Benjamin RS.

Am J Clin Oncol. 1998 Jun;21(3):317-21.PMID: 9626808 [PubMed - indexed for MEDLINE]Related articles

Thrombopoietin mobilizes CD34+ cell subsets into peripheral blood and expands multilineage progenitors in bone marrow of cancer patients with normal hematopoiesis.

Murray LJ, Luens KM, Estrada MF, Bruno E, Hoffman R, Cohen RL, Ashby MA, Vadhan-Raj S.

Exp Hematol. 1998 Mar;26(3):207-16.PMID: 9502616 [PubMed - indexed for MEDLINE]Related articles

Integration of filgrastim into chemoradiation for limited small cell lung cancer: a Phase I study.

Glisson B, Komaki R, Lee JS, Shin DM, Fossella F, Murphy WK, Kurie J, Perez-Soler R, Schea R, Vadhan-Raj S.

Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):331-6.PMID: 9457817 [PubMed - indexed for MEDLINE]Related articles

High-dose ifosfamide in bone and soft tissue sarcomas: results of phase II and pilot studies--dose-response and schedule dependence.

Patel SR, Vadhan-Raj S, Papadopolous N, Plager C, Burgess MA, Hays C, Benjamin RS.

J Clin Oncol. 1997 Jun;15(6):2378-84.PMID: 9196153 [PubMed - indexed for MEDLINE]Related articles

[Myelodysplastic syndromes]

Raza A, Vadhan-Raj S, Chávez-Sánchez G.

Rev Invest Clin. 1997 May;49 Suppl 1:15-21. Review. Spanish. No abstract available. PMID: 9380984 [PubMed - indexed for MEDLINE]Related articles

Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer.

Vadhan-Raj S, Murray LJ, Bueso-Ramos C, Patel S, Reddy SP, Hoots WK, Johnston T, Papadopolous NE, Hittelman WN, Johnston DA, Yang TA, Paton VE, Cohen RL, Hellmann SD, Benjamin RS, Broxmeyer HE.

Ann Intern Med. 1997 May 1;126(9):673-81.PMID: 9139552 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group.

Glaspy J, Bukowski R, Steinberg D, Taylor C, Tchekmedyian S, Vadhan-Raj S.

J Clin Oncol. 1997 Mar;15(3):1218-34.PMID: 9060566 [PubMed - indexed for MEDLINE]Related articles

Recombinant interleukin-2 in combination with recombinant interferon-gamma in patients with advanced malignancy: a phase 1 study.

Reddy SP, Harwood RM, Moore DF, Grimm EA, Murray JL, Vadhan-Raj S.

J Immunother. 1997 Jan;20(1):79-87.PMID: 9101417 [PubMed - indexed for MEDLINE]Related articles

Remission of advanced uterine leiomyosarcoma with pulmonary metastases with carboplatin and paclitaxel.

Kudelka AP, Termrungruanglert W, Vadhan-Raj S, Edwards CL, Varma DG, Tornos C, Verschraegen CF, Kavanagh JJ.

Anticancer Drugs. 1996 Nov;7(8):885-9.PMID: 8991194 [PubMed - indexed for MEDLINE]Related articles

Effects of interleukin-1 alpha on ovarian carcinoma in patients with recurrent disease.

Verschraegen CF, Kudelka AP, Termrungruanglert W, de Leon CG, Edwards CL, Freedman RS, Kavanagh JJ, Vadhan-Raj S.

Eur J Cancer. 1996 Aug;32A(9):1609-11.PMID: 8911126 [PubMed - indexed for MEDLINE]Related articles

Phase Ia/Ib trial of anti-GD2 chimeric monoclonal antibody 14.18 (ch14.18) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in metastatic melanoma.

Murray JL, Kleinerman ES, Jia SF, Rosenblum MG, Eton O, Buzaid A, Legha S, Ross MI, Thompson L, Mujoo K, Rieger PT, Saleh M, Khazaeli MB, Vadhan-Raj S.

J Immunother Emphasis Tumor Immunol. 1996 May;19(3):206-17.PMID: 8811495 [PubMed - indexed for MEDLINE]Related articles

Thrombopoietin suppresses apoptosis and behaves as a survival factor for the human growth factor-dependent cell line, M07e.

Ritchie A, Vadhan-Raj S, Broxmeyer HE.

Stem Cells. 1996 May;14(3):330-6.PMID: 8724699 [PubMed - indexed for MEDLINE]Related articlesFree article