PubMed

Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time.

Gallwitz B, Vaag A, Falahati A, Madsbad S.

Int J Clin Pract. 2009 Nov 19. [Epub ahead of print]PMID: 19925617 [PubMed - as supplied by publisher]Related articles

Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial.

Lund SS, Tarnow L, Frandsen M, Nielsen BB, Hansen BV, Pedersen O, Parving HH, Vaag AA.

BMJ. 2009 Nov 9;339:b4324. doi: 10.1136/bmj.b4324.PMID: 19900993 [PubMed - in process]Related articlesFree article

Dissociation between Skeletal Muscle Inhibitor-{kappa}B Kinase/Nuclear Factor-{kappa}B Pathway Activity and Insulin Sensitivity in Nondiabetic Twins.

Friedrichsen M, Ribel-Madsen R, Wojtaszewski J, Grunnet L, Richter EA, Billestrup N, Ploug T, Vaag A, Poulsen P.

J Clin Endocrinol Metab. 2009 Oct 29. [Epub ahead of print]PMID: 19875481 [PubMed - as supplied by publisher]Related articles

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.

Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, Järvelin MR, Laitinen J, Lauritzen T, Marre M, Mazur A, Meyre D, Montpetit A, Pisinger C, Posner B, Poulsen P, Pouta A, Prentki M, Ribel-Madsen R, Ruokonen A, Sandbaek A, Serre D, Tichet J, Vaxillaire M, Wojtaszewski JF, Vaag A, Hansen T, Polychronakos C, Pedersen O, Froguel P, Sladek R.

Nat Genet. 2009 Oct;41(10):1110-5. Epub 2009 Sep 6. Erratum in: Nat Genet. 2009 Oct;41(10):1156. PMID: 19734900 [PubMed - indexed for MEDLINE]Related articles

Diminished Insulin-Mediated Forearm Blood Flow and Muscle Glucose Uptake in Young Men with Low Birth Weight.

Sonne MP, Højbjerre L, Alibegovic AC, Vaag A, Stallknecht B, Dela F.

J Vasc Res. 2009 Sep 4;47(2):139-147. [Epub ahead of print]PMID: 19729960 [PubMed - as supplied by publisher]Related articles

Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes.

Alibegovic AC, Højbjerre L, Sonne MP, van Hall G, Stallknecht B, Dela F, Vaag A.

Diabetes. 2009 Dec;58(12):2749-56. Epub 2009 Aug 31.PMID: 19720789 [PubMed - in process]Related articles

Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial.

Russell-Jones D, Vaag A, Schmitz O, Sethi BK, Lalic N, Antic S, Zdravkovic M, Ravn GM, Simó R; Liraglutide Effect and Action in Diabetes 5 (LEAD-5) met+SU Study Group.

Diabetologia. 2009 Oct;52(10):2046-55. Epub 2009 Aug 14.PMID: 19688338 [PubMed - in process]Related articlesFree article

Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes.

Brøns C, Vaag A.

J Physiol. 2009 Aug 15;587(Pt 16):3977-8. No abstract available. PMID: 19684225 [PubMed - in process]Related articles

Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention.

Haugaard SB, Vaag A, Mu H, Madsbad S.

Lipids Health Dis. 2009 Aug 13;8:34.PMID: 19678948 [PubMed - in process]Related articlesFree article

Genetic and metabolic effects on skeletal muscle AMPK in young and older twins.

Mortensen B, Poulsen P, Wegner L, Stender-Petersen KL, Ribel-Madsen R, Friedrichsen M, Birk JB, Vaag A, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2009 Aug 11. [Epub ahead of print]PMID: 19671840 [PubMed - as supplied by publisher]Related articles

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.

Rose CS, Grarup N, Krarup NT, Poulsen P, Wegner L, Nielsen T, Banasik K, Faerch K, Andersen G, Albrechtsen A, Borch-Johnsen K, Clausen JO, Jørgensen T, Vaag A, Pedersen O, Hansen T.

Diabetologia. 2009 Oct;52(10):2122-9. Epub 2009 Aug 8.PMID: 19669124 [PubMed - in process]Related articles

Gene expression in skeletal muscle biopsies from people with type 2 diabetes and relatives: differential regulation of insulin signaling pathways.

Palsgaard J, Brøns C, Friedrichsen M, Dominguez H, Jensen M, Storgaard H, Spohr C, Torp-Pedersen C, Borup R, De Meyts P, Vaag A.

PLoS One. 2009 Aug 11;4(8):e6575.PMID: 19668377 [PubMed - in process]Related articlesFree article

Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?

Faerch K, Borch-Johnsen K, Holst JJ, Vaag A.

Diabetologia. 2009 Sep;52(9):1714-23. Epub 2009 Jul 10.PMID: 19590846 [PubMed - in process]Related articles

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

Grunnet LG, Nilsson E, Ling C, Hansen T, Pedersen O, Groop L, Vaag A, Poulsen P.

Diabetes. 2009 Oct;58(10):2402-8. Epub 2009 Jul 8.PMID: 19587359 [PubMed - indexed for MEDLINE]Related articles

Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association: response to Skyler et al.

Lund SS, Vaag AA.

Diabetes Care. 2009 Jul;32(7):e90-1; author reply e92-3. No abstract available. PMID: 19564469 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of adjunct metformin treatment on levels of plasma lipids in patients with type 1 diabetes.

Lund SS, Tarnow L, Astrup AS, Hovind P, Jacobsen PK, Alibegovic AC, Parving I, Pietraszek L, Frandsen M, Rossing P, Parving HH, Vaag AA.

Diabetes Obes Metab. 2009 Oct;11(10):966-77. Epub 2009 Jun 25.PMID: 19558610 [PubMed - in process]Related articles

Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

Larsen CM, Faulenbach M, Vaag A, Ehses JA, Donath MY, Mandrup-Poulsen T.

Diabetes Care. 2009 Sep;32(9):1663-8. Epub 2009 Jun 19.PMID: 19542207 [PubMed - indexed for MEDLINE]Related articles

IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes.

Berchtold LA, Larsen CM, Vaag A, Faulenbach M, Workman CT, Kruhøffer M, Donath M, Mandrup-Poulsen T.

Eur Cytokine Netw. 2009 Jun 1;20(2):81-87.PMID: 19541594 [PubMed - as supplied by publisher]Related articles

Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: results from a randomized 7-day supplementation study in prepubertal boys.

Hoppe C, Mølgaard C, Dalum C, Vaag A, Michaelsen KF.

Eur J Clin Nutr. 2009 Sep;63(9):1076-83. Epub 2009 May 27.PMID: 19471293 [PubMed - indexed for MEDLINE]Related articles

[Anti-diabetic treatment, insulin resistance and cardiovascular disease in patients with type 2 diabetes]

Hemmingsen B, Lund SS, Vaag A.

Ugeskr Laeger. 2009 May 4;171(19):1598-602. Review. Danish. PMID: 19419642 [PubMed - indexed for MEDLINE]Related articles

Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control.

Haugaard SB, Mu H, Vaag A, Madsbad S.

Eur J Endocrinol. 2009 Jul;161(1):57-64. Epub 2009 May 5.PMID: 19417077 [PubMed - indexed for MEDLINE]Related articles

Age-dependent nongenetic influences of birth weight and adult body fat on insulin sensitivity in twins.

Monrad RN, Grunnet LG, Rasmussen EL, Malis C, Vaag A, Poulsen P.

J Clin Endocrinol Metab. 2009 Jul;94(7):2394-9. Epub 2009 May 5.PMID: 19417034 [PubMed - indexed for MEDLINE]Related articles

Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study.

Faerch K, Vaag A, Witte DR, Jørgensen T, Pedersen O, Borch-Johnsen K.

Diabet Med. 2009 Apr;26(4):377-83.PMID: 19388967 [PubMed - indexed for MEDLINE]Related articles

Interstitial concentrations of adipokines in subcutaneous abdominal and femoral adipose tissue.

Nielsen NB, Højbjerre L, Sonne MP, Alibegovic AC, Vaag A, Dela F, Stallknecht B.

Regul Pept. 2009 Jun 5;155(1-3):39-45. Epub 2009 Apr 17.PMID: 19376162 [PubMed - indexed for MEDLINE]Related articles

Oral hypoglycaemic agents, insulin resistance and cardiovascular disease in patients with type 2 diabetes.

Hemmingsen B, Lund SS, Wetterslev J, Vaag A.

Eur J Endocrinol. 2009 Jul;161(1):1-9. Epub 2009 Apr 15. Review.PMID: 19369429 [PubMed - indexed for MEDLINE]Related articlesFree article

Letter by Lund et al regarding article, "fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events".

Lund SS, Vaag AA, Jensen T.

Circulation. 2009 Apr 7;119(13):e384; author reply e385. No abstract available. PMID: 19349329 [PubMed - indexed for MEDLINE]Related articles

Increased risk of type 2 diabetes in elderly twins.

Poulsen P, Grunnet LG, Pilgaard K, Storgaard H, Alibegovic A, Sonne MP, Carstensen B, Beck-Nielsen H, Vaag A.

Diabetes. 2009 Jun;58(6):1350-5. Epub 2009 Mar 31.PMID: 19336677 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men.

Brøns C, Jensen CB, Storgaard H, Hiscock NJ, White A, Appel JS, Jacobsen S, Nilsson E, Larsen CM, Astrup A, Quistorff B, Vaag A.

J Physiol. 2009 May 15;587(Pt 10):2387-97. Epub 2009 Mar 30.PMID: 19332493 [PubMed - indexed for MEDLINE]Related articles

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. Epub 2009 Mar 14.PMID: 19288077 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.

Rönn T, Poulsen P, Tuomi T, Isomaa B, Groop L, Vaag A, Ling C.

PLoS One. 2009;4(3):e4793. Epub 2009 Mar 10.PMID: 19274082 [PubMed - indexed for MEDLINE]Related articlesFree article

Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial.

Lundby Christensen L, Almdal T, Boesgaard T, Breum L, Dunn E, Gade-Rasmussen B, Gluud C, Hedetoft C, Jarloev A, Jensen T, Krarup T, Johansen LB, Lund SS, Madsbad S, Mathiesen E, Moelvig J, Nielsen F, Perrild H, Pedersen O, Roeder M, Sneppen SB, Snorgaard O, Tarnow L, Thorsteinsson B, Vaag A, Vestergaard H, Wetterslev J, Wiinberg N; CIMT Trial Group.

Diabetes Obes Metab. 2009 Apr;11(4):315-22.PMID: 19267709 [PubMed - in process]Related articles

[Future breakthroughs in medical treatment of age-related conditions]

Vaag A, Petersen JS.

Ugeskr Laeger. 2009 Mar 2;171(10):794-6. Danish. PMID: 19265603 [PubMed - indexed for MEDLINE]Related articles

Follow-up of intensive glucose control in type 2 diabetes.

Lund SS, Rossing P, Vaag AA.

N Engl J Med. 2009 Jan 22;360(4):416; author reply 418. No abstract available. PMID: 19164195 [PubMed - indexed for MEDLINE]Related articles

Low birth weight and early weight gain in the metabolic syndrome: consequences for infant nutrition.

Vaag A.

Int J Gynaecol Obstet. 2009 Mar;104 Suppl 1:S32-4. Epub 2009 Jan 19. Review.PMID: 19155006 [PubMed - indexed for MEDLINE]Related articles

Neuroendocrine, metabolic and pharmacological control of feeding behaviour--closing in on antiobesity treatment.

Vaag A.

J Physiol. 2009 Jan 15;587(Pt 1):17-8. No abstract available. PMID: 19119183 [PubMed - indexed for MEDLINE]Related articles

Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus.

Sonne MP, Højbjerre L, Alibegovic AA, Vaag A, Stallknecht B, Dela F.

Metabolism. 2009 Jan;58(1):93-101.PMID: 19059536 [PubMed - indexed for MEDLINE]Related articles

Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study.

Faerch K, Vaag A, Holst JJ, Hansen T, Jørgensen T, Borch-Johnsen K.

Diabetes Care. 2009 Mar;32(3):439-44. Epub 2008 Dec 3.PMID: 19056613 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.

Jensen CB, Martin-Gronert MS, Storgaard H, Madsbad S, Vaag A, Ozanne SE.

PLoS One. 2008;3(11):e3738. Epub 2008 Nov 17.PMID: 19011679 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibers and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609.

Grunnet LG, Brøns C, Jacobsen S, Nilsson E, Astrup A, Hansen T, Pedersen O, Poulsen P, Quistorff B, Vaag A.

J Clin Endocrinol Metab. 2009 Feb;94(2):596-602. Epub 2008 Nov 4.PMID: 18984658 [PubMed - indexed for MEDLINE]Related articles

Effect of adjunct metformin treatment in patients with type-1 diabetes and persistent inadequate glycaemic control. A randomized study.

Lund SS, Tarnow L, Astrup AS, Hovind P, Jacobsen PK, Alibegovic AC, Parving I, Pietraszek L, Frandsen M, Rossing P, Parving HH, Vaag AA.

PLoS One. 2008;3(10):e3363. Epub 2008 Oct 9.PMID: 18852875 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinol-binding protein 4 in twins: regulatory mechanisms and impact of circulating and tissue expression levels on insulin secretion and action.

Ribel-Madsen R, Friedrichsen M, Vaag A, Poulsen P.

Diabetes. 2009 Jan;58(1):54-60. Epub 2008 Oct 13.PMID: 18852328 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial function in skeletal muscle is normal and unrelated to insulin action in young men born with low birth weight.

Brøns C, Jensen CB, Storgaard H, Alibegovic A, Jacobsen S, Nilsson E, Astrup A, Quistorff B, Vaag A.

J Clin Endocrinol Metab. 2008 Oct;93(10):3885-92. Epub 2008 Jul 15.PMID: 18628517 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.

Wegner L, Hussain MS, Pilgaard K, Hansen T, Pedersen O, Vaag A, Poulsen P.

J Clin Endocrinol Metab. 2008 Oct;93(10):4013-9. Epub 2008 Jul 8.PMID: 18611970 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained postprandial decrease in plasma levels of LDL cholesterol in patients with type-2 diabetes mellitus.

Lund SS, Petersen M, Frandsen M, Smidt UM, Parving HH, Vaag AA, Jensen T.

Scand J Clin Lab Invest. 2008 Apr 16:1-14. [Epub ahead of print]PMID: 18609081 [PubMed - as supplied by publisher]Related articles

Sex and muscle structural lipids in obese subjects - an impact on insulin action?

Haugaard SB, Vaag A, Høy CE, Madsbad S.

Eur J Clin Invest. 2008 Jul;38(7):494-501.PMID: 18578691 [PubMed - indexed for MEDLINE]Related articles

The effect of birthweight upon insulin resistance and associated cardiovascular risk factors in adolescence is not explained by fetal growth velocity in the third trimester as measured by repeated ultrasound fetometry.

Vielwerth SE, Jensen RB, Larsen T, Holst KK, Mølgaard C, Greisen G, Vaag A.

Diabetologia. 2008 Aug;51(8):1483-92. Epub 2008 May 21.PMID: 18493737 [PubMed - indexed for MEDLINE]Related articles

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle.

Rönn T, Poulsen P, Hansson O, Holmkvist J, Almgren P, Nilsson P, Tuomi T, Isomaa B, Groop L, Vaag A, Ling C.

Diabetologia. 2008 Jul;51(7):1159-68. Epub 2008 May 17.PMID: 18488190 [PubMed - indexed for MEDLINE]Related articles

To be predisposed to insulin resistance and type 2 diabetes.

Vaag A.

J Physiol. 2008 May 15;586(10):2421. Review. No abstract available. PMID: 18480384 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular correlates for maximal oxygen uptake and type 1 fibers.

Parikh H, Nilsson E, Ling C, Poulsen P, Almgren P, Nittby H, Eriksson KF, Vaag A, Groop LC.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1152-9. Epub 2008 Apr 29.PMID: 18445752 [PubMed - indexed for MEDLINE]Related articlesFree article