PubMed

Time-dependent Inhibitory Effects of FK1706, a Novel Non-immunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in Vitro.

Minematsu T, Lee J, Zha J, Moy S, Kowalski D, Hori K, Ishibashi K, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Nov 4. [Epub ahead of print]PMID: 19889885 [PubMed - as supplied by publisher]Related articles

Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice.

Sasaki N, Yamashita T, Takeda M, Shinohara M, Nakajima K, Tawa H, Usui T, Hirata K.

Circulation. 2009 Nov 17;120(20):1996-2005. Epub 2009 Nov 2.PMID: 19884470 [PubMed - in process]Related articles

Selective Isolation of Young Cells from Human Corneal Endothelium by the Sphere-Forming Assay.

Mimura T, Yamagami S, Yokoo S, Usui T, Amano S.

Tissue Eng Part C Methods. 2009 Oct 23. [Epub ahead of print]PMID: 19852617 [PubMed - as supplied by publisher]Related articles

Integrative systems control approach for reactivating Kaposi's sarcoma-associated herpesvirus (KSHV) with combinatory drugs.

Sun CP, Usui T, Yu F, Al-Shyoukh I, Shamma J, Sun R, Ho CM.

Integr Biol. 2009 Jan 1;1(1):123-130.PMID: 19851479 [PubMed]Related articlesFree article

Characterization of human organic cation transporter 1 (OCT1/SLC22A1)-, and OCT2 (SLC22A2)-mediated transport of YM155 monobromide, a novel survivin suppressant.

Minematsu T, Iwai M, Umehara KI, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Oct 15. [Epub ahead of print]PMID: 19833842 [PubMed - as supplied by publisher]Related articles

Discovery of boron-conjugated 4-anilinoquinazoline as a prolonged inhibitor of EGFR tyrosine kinase.

Ban HS, Usui T, Nabeyama W, Morita H, Fukuzawa K, Nakamura H.

Org Biomol Chem. 2009 Nov 7;7(21):4415-27. Epub 2009 Aug 20.PMID: 19830290 [PubMed - in process]Related articles

Descemet stripping automated endothelial keratoplasty using cultured corneal endothelial cells in a rabbit model.

Honda N, Mimura T, Usui T, Amano S.

Arch Ophthalmol. 2009 Oct;127(10):1321-6.PMID: 19822849 [PubMed - indexed for MEDLINE]Related articles

Severe hyperopic shift and irregular astigmatism after radial keratotomy.

Mimura T, Fujimura S, Yamagami S, Usui T, Honda N, Shirakawa R, Fukuoka S, Amano S.

Eye Contact Lens. 2009 Nov;35(6):345-7.PMID: 19812501 [PubMed - in process]Related articles

Multidendritic sensory neurons in the adult Drosophila abdomen: origins, dendritic morphology, and segment- and age-dependent programmed cell death.

Shimono K, Fujimoto A, Tsuyama T, Yamamoto-Kochi M, Sato M, Hattori Y, Sugimura K, Usui T, Kimura K, Uemura T.

Neural Dev. 2009 Oct 2;4:37.PMID: 19799768 [PubMed - in process]Related articlesFree article

Evolutionary genetics of highly pathogenic H5N1 avian influenza viruses isolated from whooper swans in northern Japan in 2008.

Usui T, Yamaguchi T, Ito H, Ozaki H, Murase T, Ito T.

Virus Genes. 2009 Oct 2. [Epub ahead of print]PMID: 19798563 [PubMed - as supplied by publisher]Related articles

Relationship between myopia and allergen-specific serum IgE levels in patients with allergic conjunctivitis.

Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Amano S.

Clin Experiment Ophthalmol. 2009 Sep;37(7):670-7.PMID: 19788663 [PubMed - indexed for MEDLINE]Related articles

Pharmacological profile and clinical efficacy of minodronic acid hydrate as a new therapeutic agent for osteoporosis.

Tanaka M, Mori H, Shimizu K, Toshiyuki, Matsuoka, Yamamotoya H, Minamide T, Mori M, Nozaki K, Usui T, Shimokawa K, Suzuki H, Aoyama K, Kimoto A, Sasamata M, Miyata K.

Nippon Yakurigaku Zasshi. 2009 Sep;134(3):149-57. Review. No abstract available. PMID: 19749488 [PubMed - indexed for MEDLINE]Related articles

Recent Causes of Subconjunctival Hemorrhage.

Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.

Ophthalmologica. 2009 Sep 9;224(3):133-137. [Epub ahead of print]PMID: 19738393 [PubMed - as supplied by publisher]Related articles

Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise.

Ueda SY, Yoshikawa T, Katsura Y, Usui T, Fujimoto S.

J Endocrinol. 2009 Dec;203(3):357-64. Epub 2009 Sep 8.PMID: 19737911 [PubMed - in process]Related articles

Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

Usui T, Mise M, Hashizume T, Yabuki M, Komuro S.

Drug Metab Dispos. 2009 Dec;37(12):2383-92. Epub 2009 Aug 31.PMID: 19720731 [PubMed - in process]Related articlesFree article

Location and Extent of Subconjunctival Hemorrhage.

Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Fukuoka S, Hotta H, Amano S.

Ophthalmologica. 2009 Aug 28;224(2):90-95. [Epub ahead of print]PMID: 19713719 [PubMed - as supplied by publisher]Related articles

Investigation of long-term retention of unchanged (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, a novel "funny" if current channel inhibitor, and its metabolites in the eyeball and thoracic aorta of rats.

Umehara K, Nakada N, Noguchi K, Iwatsubo T, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Nov;37(11):2137-44. Epub 2009 Aug 24.PMID: 19704029 [PubMed - in process]Related articles

Association of a single nucleotide polymorphism in the constitutive androstane receptor gene with bone mineral density.

Urano T, Usui T, Shiraki M, Ouchi Y, Inoue S.

Geriatr Gerontol Int. 2009 Sep;9(3):235-41.PMID: 19702932 [PubMed - in process]Related articles

Pupillography of automated swinging flashlight test in amblyopia.

Miki A, Iijima A, Takagi M, Yaoeda K, Usui T, Hasegawa S, Abe H, Bando T.

Clin Ophthalmol. 2008 Dec;2(4):781-6.PMID: 19668431 [PubMed - in process]Related articlesFree article

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.

Albuquerque RJ, Hayashi T, Cho WG, Kleinman ME, Dridi S, Takeda A, Baffi JZ, Yamada K, Kaneko H, Green MG, Chappell J, Wilting J, Weich HA, Yamagami S, Amano S, Mizuki N, Alexander JS, Peterson ML, Brekken RA, Hirashima M, Capoor S, Usui T, Ambati BK, Ambati J.

Nat Med. 2009 Sep;15(9):1023-30. Epub 2009 Aug 9.PMID: 19668192 [PubMed - indexed for MEDLINE]Related articles

Leukoencephalopathy with cognitive impairment following tocilizumab for the treatment of rheumatoid arthritis (RA).

Kobayashi K, Okamoto Y, Inoue H, Usui T, Ihara M, Kawamata J, Miki Y, Mimori T, Tomimoto H, Takahashi R.

Intern Med. 2009;48(15):1307-9. Epub 2009 Aug 3.PMID: 19652436 [PubMed - indexed for MEDLINE]Related articlesFree article

Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.

Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T, Shimizu M, Kawabata D, Yukawa N, Hashimoto M, Sakaguchi N, Sakaguchi S, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Mimori T.

Arthritis Rheum. 2009 Aug;60(8):2294-303.PMID: 19644886 [PubMed - indexed for MEDLINE]Related articles

Subconjunctival hemorrhage and conjunctivochalasis.

Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Shirakawa R, Hotta H, Amano S.

Ophthalmology. 2009 Oct;116(10):1880-6.PMID: 19596440 [PubMed - indexed for MEDLINE]Related articles

Vaccination with autoreactive CD4(+)Th1 clones in lupus-prone MRL/Mp-Fas(lpr/lpr) mice.

Fujii T, Okada M, Fujita Y, Sato T, Tanaka M, Usui T, Umehara H, Mimori T.

J Autoimmun. 2009 Sep;33(2):125-34. Epub 2009 Jul 12.PMID: 19596182 [PubMed - indexed for MEDLINE]Related articles

The cytotoxic macrolide FD-891 induces caspase-8-dependent mitochondrial release of cytochrome c and subsequent apoptosis in human leukemia Jurkat cells.

Inaba S, Eguchi T, Motegi A, Mizoue K, Usui T, Nagai K, Kataoka T.

J Antibiot (Tokyo). 2009 Sep;62(9):507-12. Epub 2009 Jul 10.PMID: 19590527 [PubMed - in process]Related articles

A1330V variant of the low-density lipoprotein receptor-related protein 5 (LRP5) gene decreases Wnt signaling and affects the total body bone mineral density in Japanese women.

Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S.

Endocr J. 2009 Aug;56(4):625-31. Epub 2009 Jul 1.PMID: 19571442 [PubMed - indexed for MEDLINE]Related articlesFree article

The generation of lucigenin chemiluminescence from the reaction of guanidino compounds with phenylglyoxal under alkaline conditions and its application.

Nohara Y, Usui T, Suzuki J, Hanai T, Kinoshita T, Nakagomi K, Watanabe M.

Chem Pharm Bull (Tokyo). 2009 Jul;57(7):700-3.PMID: 19571414 [PubMed - indexed for MEDLINE]Related articlesFree article

Predominant Expression of Mutated Allele of the Succunate Dehydrogenase D (SDHD) Gene in the SDHD-related Paragangliomas.

Yamashita R, Usui T, Hashimoto S, Suzuki H, Takahashi M, Honkura K, Iwamoto K, Kodama E, Tagami T, Naruse M, Shimatsu A, Kaise K.

Endocr J. 2009 Jun 24. [Epub ahead of print]PMID: 19550080 [PubMed - as supplied by publisher]Related articlesFree article

Involvement of human organic cation transporter 1 in the hepatic uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel, small molecule survivin suppressant.

Iwai M, Minematsu T, Narikawa S, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Sep;37(9):1856-63. Epub 2009 Jun 11.PMID: 19520775 [PubMed - in process]Related articles

Crystal deposits on the lens capsules in Bietti crystalline corneoretinal dystrophy associated with a mutation in the CYP4V2 gene.

Yokoi Y, Nakazawa M, Mizukoshi S, Sato K, Usui T, Takeuchi K.

Acta Ophthalmol. 2009 Jun 5. [Epub ahead of print]PMID: 19508456 [PubMed - as supplied by publisher]Related articles

Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae.

Ogata M, Nakajima M, Kato T, Obara T, Yagi H, Kato K, Usui T, Park EY.

BMC Biotechnol. 2009 Jun 5;9:54.PMID: 19500344 [PubMed - indexed for MEDLINE]Related articlesFree article

The development of a non-contact screening system for rapid medical inspection at a quarantine depot using a laser Doppler blood-flow meter, microwave radar and infrared thermography.

Matsui T, Suzuki S, Ujikawa K, Usui T, Gotoh S, Sugamata M, Abe S.

J Med Eng Technol. 2009;33(6):481-7.PMID: 19484686 [PubMed - in process]Related articles

Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response.

Stracker TH, Usui T, Petrini JH.

DNA Repair (Amst). 2009 Sep 2;8(9):1047-54. Epub 2009 May 26. Review.PMID: 19473886 [PubMed - indexed for MEDLINE]Related articles

Development of a non-contact screening system for rapid medical inspection at a quarantine depot using a laser Doppler blood-flow meter, microwave radar and infrared thermography.

Matsui T, Suzuki S, Ujikawa K, Usui T, Gotoh S, Sugamata M, Badarch Z, Abe S.

J Med Eng Technol. 2009;33(5):403-9.PMID: 19440915 [PubMed - indexed for MEDLINE]Related articles

Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.

Umehara K, Shirai N, Iwatsubo T, Noguchi K, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Aug;37(8):1646-57. Epub 2009 May 13.PMID: 19439489 [PubMed - indexed for MEDLINE]Related articles

Molecular Design of Spacer-N-Linked Sialoglycopolypeptide as Polymeric Inhibitors Against Influenza Virus Infection.

Ogata M, Hidari KI, Kozaki W, Murata T, Hiratake J, Park EY, Suzuki T, Usui T.

Biomacromolecules. 2009 May 13. [Epub ahead of print]PMID: 19438195 [PubMed - as supplied by publisher]Related articles

Genetic analysis of two Japanese patients with non-classical 21-hydroxylase deficiency.

Imamine R, Arima H, Kusakabe M, Umeda H, Sato I, Homma K, Usui T, Oiso Y.

Intern Med. 2009;48(9):705-9. Epub 2009 May 1.PMID: 19420818 [PubMed - in process]Related articlesFree article

R27X nonsense mutation of the SDHB gene in a patient with sporadic malignant paraganglioma.

Naito M, Usui T, Tamanaha T, Kawashima ST, Iogawa H, Hagiwara H, Kimura T, Tagami T, Kurosawa M, Shimatsu A, Naruse M.

Endocrine. 2009 Aug;36(1):10-5. Epub 2009 May 5.PMID: 19415531 [PubMed - indexed for MEDLINE]Related articles

Conjunctivochalasis and contact lenses.

Mimura T, Usui T, Yamamoto H, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Amano S.

Am J Ophthalmol. 2009 Jul;148(1):20-5.e1. Epub 2009 Apr 29.PMID: 19403112 [PubMed - indexed for MEDLINE]Related articles

Increased prevalence and clonal dissemination of multidrug-resistant Pseudomonas aeruginosa with the blaIMP-1 gene cassette in Hiroshima.

Kouda S, Ohara M, Onodera M, Fujiue Y, Sasaki M, Kohara T, Kashiyama S, Hayashida S, Harino T, Tsuji T, Itaha H, Gotoh N, Matsubara A, Usui T, Sugai M.

J Antimicrob Chemother. 2009 Jul;64(1):46-51. Epub 2009 Apr 27.PMID: 19398456 [PubMed - indexed for MEDLINE]Related articles

Enzymatic synthesis of gentiooligosaccharides by transglycosylation with beta-glycosidases from Penicillium multicolor.

Fujimoto Y, Hattori T, Uno S, Murata T, Usui T.

Carbohydr Res. 2009 May 26;344(8):972-8. Epub 2009 Mar 12.PMID: 19362709 [PubMed - indexed for MEDLINE]Related articles

Relationship between exposure of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a "funny" if current channel inhibitor, and heart rate reduction in tachycardia-induced beagle dogs.

Umehara K, Wada K, Noguchi K, Iwatsubo T, Usui T, Kamimura H.

Drug Metab Dispos. 2009 Jul;37(7):1427-33. Epub 2009 Apr 9.PMID: 19359407 [PubMed - indexed for MEDLINE]Related articles

TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase.

Urano T, Usui T, Takeda S, Ikeda K, Okada A, Ishida Y, Iwayanagi T, Otomo J, Ouchi Y, Inoue S.

Biochem Biophys Res Commun. 2009 May 29;383(2):263-8. Epub 2009 Apr 7.PMID: 19358823 [PubMed - indexed for MEDLINE]Related articles

Five-year longitudinal effect of radical perineal prostatectomy on health-related quality of life in Japanese men, using general and disease-specific measures.

Inoue S, Shiina H, Hiraoka T, Wake K, Sumura M, Honda S, Urakami S, Igawa M, Usui T.

BJU Int. 2009 Oct;104(8):1077-84. Epub 2009 Mar 13.PMID: 19338553 [PubMed - indexed for MEDLINE]Related articles

Decrease of renal function due to warm ischemia after laparoscopic partial nephrectomy: evaluation using 99mTc-DMSA renal scintigraphy.

Tachikake T, Shigeta M, Mita K, Marukawa K, Usui T, Ito K.

Urol Int. 2009;82(2):162-5. Epub 2009 Mar 19.PMID: 19322002 [PubMed - indexed for MEDLINE]Related articles

Development of the human retroperitoneal fasciae.

Matsubara A, Murakami G, Niikura H, Kinugasa Y, Fujimiya M, Usui T.

Cells Tissues Organs. 2009;190(5):286-96. Epub 2009 Mar 24.PMID: 19321993 [PubMed - in process]Related articles

Transmission of the parasite Ichthyophonus hoferi in cultured rainbow trout and comparison of epidemic models.

Yokota M, Watanabe S, Hatai K, Kurata O, Furihata M, Usui T.

J Aquat Anim Health. 2008 Dec;20(4):207-14.PMID: 19306610 [PubMed - indexed for MEDLINE]Related articles

Bone mass effects of a Smad6 gene polymorphism in Japanese postmenopausal women.

Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S.

J Bone Miner Metab. 2009;27(5):562-6. Epub 2009 Mar 10.PMID: 19277452 [PubMed - in process]Related articles

Purification, characterization, and cDNA cloning of a lectin from the mushroom Pleurocybella porrigens.

Suzuki T, Amano Y, Fujita M, Kobayashi Y, Dohra H, Hirai H, Murata T, Usui T, Morita T, Kawagishi H.

Biosci Biotechnol Biochem. 2009 Mar 23;73(3):702-9. Epub 2009 Mar 7.PMID: 19270381 [PubMed - indexed for MEDLINE]Related articlesFree article

Image in endocrinology. Pheochromocytoma with subclinical Cushing's syndrome caused by corticomedullary mixed tumor of the adrenal gland.

Kimura T, Usui T, Inamoto S, Minamiguchi S, Okuno H, Sasano H, Hagiwara H, Nagata D, Tagami T, Naruse M, Shimatsu A.

J Clin Endocrinol Metab. 2009 Mar;94(3):746-7. No abstract available. PMID: 19261896 [PubMed - indexed for MEDLINE]Related articles