PubMed

Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction.

Atibalentja DF, Byersdorfer CA, Unanue ER.

J Immunol. 2009 Nov 23. [Epub ahead of print]PMID: 19933868 [PubMed - as supplied by publisher]

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation.

Belizaire R, Unanue ER.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17463-8. Epub 2009 Sep 25.PMID: 19805168 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant Listeria monocytogenes expressing a cell wall-associated listeriolysin O is weakly virulent but immunogenic.

Carrero JA, Calderon B, Vivanco-Cid H, Unanue ER.

Infect Immun. 2009 Oct;77(10):4371-82. Epub 2009 Aug 10.PMID: 19667043 [PubMed - indexed for MEDLINE]Related articles

Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cells.

Chang KY, Unanue ER.

Int Immunol. 2009 Jun;21(6):705-13. Epub 2009 May 21.PMID: 19461125 [PubMed - indexed for MEDLINE]Related articlesFree article

The cellular niche of Listeria monocytogenes infection changes rapidly in the spleen.

Aoshi T, Carrero JA, Konjufca V, Koide Y, Unanue ER, Miller MJ.

Eur J Immunol. 2009 Feb;39(2):417-25.PMID: 19130474 [PubMed - indexed for MEDLINE]Related articles

Autoimmune diabetes mellitus--much progress, but many challenges.

McDevitt HO, Unanue ER.

Adv Immunol. 2008;100:1-12. Review. No abstract available. PMID: 19111161 [PubMed - indexed for MEDLINE]Related articles

Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity.

Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, Calderon B, Schraml BU, Unanue ER, Diamond MS, Schreiber RD, Murphy TL, Murphy KM.

Science. 2008 Nov 14;322(5904):1097-100.PMID: 19008445 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes.

Calderon B, Suri A, Pan XO, Mills JC, Unanue ER.

J Immunol. 2008 Nov 15;181(10):6964-74.PMID: 18981116 [PubMed - indexed for MEDLINE]Related articlesFree article

Granzymes drive a rapid listeriolysin O-induced T cell apoptosis.

Carrero JA, Vivanco-Cid H, Unanue ER.

J Immunol. 2008 Jul 15;181(2):1365-74.PMID: 18606691 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules.

Calderon B, Suri A, Miller MJ, Unanue ER.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6121-6. Epub 2008 Apr 21.PMID: 18427107 [PubMed - indexed for MEDLINE]Related articlesFree article

Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice.

Levisetti MG, Lewis DM, Suri A, Unanue ER.

Diabetes. 2008 Jul;57(7):1852-60. Epub 2008 Apr 8.PMID: 18398138 [PubMed - indexed for MEDLINE]Related articlesFree article

First signature of islet beta-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules.

Suri A, Walters JJ, Rohrs HW, Gross ML, Unanue ER.

J Immunol. 2008 Mar 15;180(6):3849-56.PMID: 18322192 [PubMed - indexed for MEDLINE]Related articlesFree article

Dressing for the occasion: APCs make antigens presentable.

Unanue ER, McCluskey J.

Curr Opin Immunol. 2008 Feb;20(1):49-51. Epub 2008 Jan 30. No abstract available. PMID: 18249104 [PubMed - indexed for MEDLINE]Related articles

Podocytes use FcRn to clear IgG from the glomerular basement membrane.

Akilesh S, Huber TB, Wu H, Wang G, Hartleben B, Kopp JB, Miner JH, Roopenian DC, Unanue ER, Shaw AS.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):967-72. Epub 2008 Jan 15.PMID: 18198272 [PubMed - indexed for MEDLINE]Related articlesFree article

Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

Suri A, Levisetti MG, Unanue ER.

Curr Opin Immunol. 2008 Feb;20(1):105-10. Epub 2007 Dec 21. Review.PMID: 18082388 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of lymphocyte apoptosis on the innate immune stages of infection.

Carrero JA, Unanue ER.

Immunol Res. 2007;38(1-3):333-41.PMID: 17917040 [PubMed - indexed for MEDLINE]Related articles

Viral infections and nonspecific protection--good or bad?

Unanue ER.

N Engl J Med. 2007 Sep 27;357(13):1345-6. No abstract available. PMID: 17898106 [PubMed - indexed for MEDLINE]Related articles

Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes. J. Immunol. 1981. 127: 1869-1875.

Ziegler K, Unanue ER.

J Immunol. 2007 Jul 1;179(1):5-11. No abstract available. PMID: 17579013 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form.

Levisetti MG, Suri A, Petzold SJ, Unanue ER.

J Immunol. 2007 May 15;178(10):6051-7.PMID: 17475829 [PubMed - indexed for MEDLINE]Related articlesFree article

Ito cells, stellate cells, and myofibroblasts: new actors in antigen presentation.

Unanue ER.

Immunity. 2007 Jan;26(1):9-10. Review.PMID: 17241956 [PubMed - indexed for MEDLINE]Related articles

Predicting peptides bound to I-Ag7 class II histocompatibility molecules using a novel expectation-maximization alignment algorithm.

Chang KY, Suri A, Unanue ER.

Proteomics. 2007 Feb;7(3):367-77.PMID: 17211830 [PubMed - indexed for MEDLINE]Related articles

Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides.

Lovitch SB, Esparza TJ, Schweitzer G, Herzog J, Unanue ER.

J Immunol. 2007 Jan 1;178(1):122-33.PMID: 17182547 [PubMed - indexed for MEDLINE]Related articlesFree article

In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.

Calderon B, Suri A, Unanue ER.

Am J Pathol. 2006 Dec;169(6):2137-47.PMID: 17148676 [PubMed - indexed for MEDLINE]Related articlesFree article

From antigen processing to peptide-MHC binding.

Unanue ER.

Nat Immunol. 2006 Dec;7(12):1277-9.PMID: 17110945 [PubMed - indexed for MEDLINE]Related articles

Lymphocyte apoptosis as an immune subversion strategy of microbial pathogens.

Carrero JA, Unanue ER.

Trends Immunol. 2006 Nov;27(11):497-503. Epub 2006 Sep 25.PMID: 16997632 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: unique T cells that recognize citrullinated peptides are a feature of protein immunization.

Ireland J, Herzog J, Unanue ER.

J Immunol. 2006 Aug 1;177(3):1421-5.PMID: 16849447 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells.

Suri A, Calderon B, Esparza TJ, Frederick K, Bittner P, Unanue ER.

Science. 2006 Mar 24;311(5768):1778-80.PMID: 16556846 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes.

Carrero JA, Calderon B, Unanue ER.

J Exp Med. 2006 Apr 17;203(4):933-40. Epub 2006 Mar 20.PMID: 16549598 [PubMed - indexed for MEDLINE]Related articlesFree article

Amino-terminal flanking residues determine the conformation of a peptide-class II MHC complex.

Lovitch SB, Pu Z, Unanue ER.

J Immunol. 2006 Mar 1;176(5):2958-68.PMID: 16493054 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of naturally processed peptides bound to the class I MHC molecule H-2Kd of normal and TAP-deficient cells.

Suri A, Walters JJ, Levisetti MG, Gross ML, Unanue ER.

Eur J Immunol. 2006 Mar;36(3):544-57.PMID: 16479539 [PubMed - indexed for MEDLINE]Related articles

The wide diversity and complexity of peptides bound to class II MHC molecules.

Suri A, Lovitch SB, Unanue ER.

Curr Opin Immunol. 2006 Feb;18(1):70-7. Epub 2005 Nov 28. Review.PMID: 16316750 [PubMed - indexed for MEDLINE]Related articles

The murine diabetogenic class II histocompatibility molecule I-Ag7: structural and functional properties and specificity of peptide selection.

Suri A, Unanue ER.

Adv Immunol. 2005;88:235-65. Review.PMID: 16227092 [PubMed - in process]Related articles

Conformational isomers of a peptide-class II major histocompatibility complex.

Lovitch SB, Unanue ER.

Immunol Rev. 2005 Oct;207:293-313. Review.PMID: 16181344 [PubMed - indexed for MEDLINE]Related articles

Diabetes is predicted by the beta cell level of autoantigen.

Byersdorfer CA, Schweitzer GG, Unanue ER.

J Immunol. 2005 Oct 1;175(7):4347-54.PMID: 16177075 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding of immunogenic peptides to Ia histocompatibility molecules. 1985.

Babbitt BP, Allen PM, Matsueda G, Haber E, Unanue ER.

J Immunol. 2005 Oct 1;175(7):4163-5. No abstract available. PMID: 16177052 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity.

Suri A, Walters JJ, Gross ML, Unanue ER.

J Clin Invest. 2005 Aug;115(8):2268-76.PMID: 16075062 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells.

Herzog J, Maekawa Y, Cirrito TP, Illian BS, Unanue ER.

Proc Natl Acad Sci U S A. 2005 May 31;102(22):7928-33. Epub 2005 May 18.PMID: 15901898 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes.

Levisetti MG, Suri A, Frederick K, Unanue ER.

Diabetes. 2004 Dec;53(12):3115-9.PMID: 15561941 [PubMed - indexed for MEDLINE]Related articlesFree article

Following immunization antigen becomes concentrated in a limited number of APCs including B cells.

Byersdorfer CA, Dipaolo RJ, Petzold SJ, Unanue ER.

J Immunol. 2004 Dec 1;173(11):6627-34.PMID: 15557153 [PubMed - indexed for MEDLINE]Related articlesFree article

Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection.

Carrero JA, Calderon B, Unanue ER.

J Exp Med. 2004 Aug 16;200(4):535-40. Epub 2004 Aug 9.PMID: 15302900 [PubMed - indexed for MEDLINE]Related articlesFree article

T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

Pu Z, Lovitch SB, Bikoff EK, Unanue ER.

Immunity. 2004 Apr;20(4):467-76.PMID: 15084275 [PubMed - indexed for MEDLINE]Related articles

Listeriolysin O from Listeria monocytogenes is a lymphocyte apoptogenic molecule.

Carrero JA, Calderon B, Unanue ER.

J Immunol. 2004 Apr 15;172(8):4866-74.PMID: 15067065 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of autoimmune diabetes by non-islet-specific T cells - a role for the glucocorticoid-induced TNF receptor.

Suri A, Shimizu J, Katz JD, Sakaguchi S, Unanue ER, Kanagawa O.

Eur J Immunol. 2004 Feb;34(2):447-54.PMID: 14768049 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice.

Levisetti MG, Suri A, Vidavsky I, Gross ML, Kanagawa O, Unanue ER.

Int Immunol. 2003 Dec;15(12):1473-83.PMID: 14645156 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of saccharide size on the cellular immune response to glycopeptides.

Mogemark M, Cirrito TP, Sjölin P, Unanue ER, Kihlberg J.

Org Biomol Chem. 2003 Jun 21;1(12):2063-9.PMID: 12945896 [PubMed - indexed for MEDLINE]Related articles

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing.

Lovitch SB, Petzold SJ, Unanue ER.

J Immunol. 2003 Sep 1;171(5):2183-6.PMID: 12928360 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular pathogens and antigen presentation-new challenges with Legionella pneumophila.

Unanue ER.

Immunity. 2003 Jun;18(6):722-4.PMID: 12818153 [PubMed - indexed for MEDLINE]Related articles

CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.

Kim JM, Wu H, Green G, Winkler CA, Kopp JB, Miner JH, Unanue ER, Shaw AS.

Science. 2003 May 23;300(5623):1298-300.PMID: 12764198 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cells process and present antigens across a range of maturation states.

Veeraswamy RK, Cella M, Colonna M, Unanue ER.

J Immunol. 2003 Jun 1;170(11):5367-72.PMID: 12759410 [PubMed - indexed for MEDLINE]Related articlesFree article

Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition.

Suri A, Walters JJ, Kanagawa O, Gross ML, Unanue ER.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5330-5. Epub 2003 Apr 7.PMID: 12682304 [PubMed - indexed for MEDLINE]Related articlesFree article