PubMed

Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes.

Smeeton F, Shojaee Moradie F, Jones RH, Westergaard L, Haahr H, Umpleby AM, Russell-Jones DL.

Diabetologia. 2009 Nov;52(11):2317-23. Epub 2009 Aug 26.PMID: 19707744 [PubMed - in process]Related articles

Effects of rosiglitazone and pioglitazone on lipoprotein metabolism in patients with Type 2 diabetes and normal lipids.

Brackenridge AL, Jackson N, Jefferson W, Stolinski M, Shojaee-Moradie F, Hovorka R, Umpleby AM, Russell-Jones D.

Diabet Med. 2009 May;26(5):532-9.PMID: 19646194 [PubMed - in process]Related articles

Pegvisomant improves insulin sensitivity and reduces overnight free fatty acid concentrations in patients with acromegaly.

Higham CE, Rowles S, Russell-Jones D, Umpleby AM, Trainer PJ.

J Clin Endocrinol Metab. 2009 Jul;94(7):2459-63. Epub 2009 Apr 14.PMID: 19366854 [PubMed - indexed for MEDLINE]Related articles

Effect of 6-month supervised exercise on low-density lipoprotein apolipoprotein B kinetics in patients with type 2 diabetes mellitus.

Stolinski M, Alam S, Jackson NC, Shojaee-Moradie F, Pentecost C, Jefferson W, Christ ER, Jones RH, Umpleby AM.

Metabolism. 2008 Nov;57(11):1608-14.PMID: 18940401 [PubMed - indexed for MEDLINE]Related articles

Severe intrauterine growth retardation and atypical diabetes associated with a translocation breakpoint disrupting regulation of the insulin-like growth factor 2 gene.

Murphy R, Baptista J, Holly J, Umpleby AM, Ellard S, Harries LW, Crolla J, Cundy T, Hattersley AT.

J Clin Endocrinol Metab. 2008 Nov;93(11):4373-80. Epub 2008 Aug 26.PMID: 18728168 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of growth hormone and/or testosterone on whole body protein kinetics and skeletal muscle gene expression in healthy elderly men: a randomized controlled trial.

Giannoulis MG, Jackson N, Shojaee-Moradie F, Nair KS, Sonksen PH, Martin FC, Umpleby AM.

J Clin Endocrinol Metab. 2008 Aug;93(8):3066-74. Epub 2008 May 13.PMID: 18477661 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients.

Burt MG, Johannsson G, Umpleby AM, Chisholm DJ, Ho KK.

J Clin Endocrinol Metab. 2008 Mar;93(3):688-95. Epub 2008 Jan 8.PMID: 18182447 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between GH-induced metabolic changes and changes in body composition: a dose and time course study in GH-deficient adults.

Burt MG, Gibney J, Hoffman DM, Umpleby AM, Ho KK.

Growth Horm IGF Res. 2008 Feb;18(1):55-64. Epub 2007 Aug 21.PMID: 17714967 [PubMed - indexed for MEDLINE]Related articles

Impact of acute and chronic low-dose glucocorticoids on protein metabolism.

Burt MG, Johannsson G, Umpleby AM, Chisholm DJ, Ho KK.

J Clin Endocrinol Metab. 2007 Oct;92(10):3923-9. Epub 2007 Jul 24.PMID: 17652216 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of non-islet cell hypoglycaemia caused by tumour-produced IGF-II.

Zachariah S, Brackenridge A, Shojaee-Moradie F, Camuncho-Hubner C, Umpleby AM, Russell-Jones D.

Clin Endocrinol (Oxf). 2007 Oct;67(4):637-8. Epub 2007 Jun 20. No abstract available. PMID: 17581259 [PubMed - indexed for MEDLINE]Related articles

Measurement of endogenous and exogenous triacylglycerol kinetics in the fed and fasted states.

Sun F, Stolinski M, Shojaee-Moradie F, Umpleby AM.

Biochem Soc Trans. 2007 Jun;35(Pt 3):482-3. Review.PMID: 17511633 [PubMed - indexed for MEDLINE]Related articles

Protein metabolism in acromegaly: differential effects of short- and long-term treatment.

Gibney J, Wolthers T, Burt MG, Leung KC, Umpleby AM, Ho KK.

J Clin Endocrinol Metab. 2007 Apr;92(4):1479-84. Epub 2007 Jan 16.PMID: 17227805 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism.

Shojaee-Moradie F, Baynes KC, Pentecost C, Bell JD, Thomas EL, Jackson NC, Stolinski M, Whyte M, Lovell D, Bowes SB, Gibney J, Jones RH, Umpleby AM.

Diabetologia. 2007 Feb;50(2):404-13. Epub 2006 Dec 6.PMID: 17149589 [PubMed - indexed for MEDLINE]Related articles

Effects of growth hormone and/or testosterone on very low density lipoprotein apolipoprotein B100 kinetics and plasma lipids in healthy elderly men: a randomised controlled trial.

Giannoulis MG, Jackson N, Shojaee-Moradie F, Sonksen PH, Martin FC, Umpleby AM.

Growth Horm IGF Res. 2006 Oct-Dec;16(5-6):308-17. Epub 2006 Oct 9.PMID: 17029996 [PubMed - indexed for MEDLINE]Related articles

Effects of recombinant human IGF-I/IGF-binding protein-3 complex on glucose and glycerol metabolism in type 1 diabetes.

Saukkonen T, Shojaee-Moradie F, Williams RM, Amin R, Yuen KC, Watts A, Acerini CL, Umpleby AM, Dunger DB.

Diabetes. 2006 Aug;55(8):2365-70.PMID: 16873702 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute regulation of plasma leptin by isoprenaline in lean and obese fasted subjects.

Baynes KC, Nicholas MD, Shojaee-Moradie F, Umpleby AM, Giannoulis MG.

Diabetes Obes Metab. 2006 Jul;8(4):412-8.PMID: 16776748 [PubMed - indexed for MEDLINE]Related articles

Low-density lipoprotein apolipoprotein B100 turnover in hypopituitary patients with GH deficiency: a stable isotope study.

Christ ER, Cummings MH, Stolinski M, Jackson N, Lumb PJ, Wierzbicki AS, Sönksen PH, Russell-Jones DL, Umpleby AM.

Eur J Endocrinol. 2006 Mar;154(3):459-66.PMID: 16498060 [PubMed - indexed for MEDLINE]Related articlesFree article

Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1beta and -1alpha mutations.

Brackenridge A, Pearson ER, Shojaee-Moradie F, Hattersley AT, Russell-Jones D, Umpleby AM.

Diabetes. 2006 Feb;55(2):405-11.PMID: 16443774 [PubMed - indexed for MEDLINE]Related articlesFree article

In treatment-naïve and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100.

Das S, Shahmanesh M, Stolinski M, Shojaee-Moradie F, Jefferson W, Jackson NC, Cobbold M, Nightingale P, Umpleby AM.

Diabetologia. 2006 Mar;49(3):538-42. Epub 2006 Jan 24.PMID: 16432707 [PubMed - indexed for MEDLINE]Related articles

Effects of high-dose growth hormone on glucose and glycerol metabolism at rest and during exercise in endurance-trained athletes.

Healy ML, Gibney J, Pentecost C, Croos P, Russell-Jones DL, Sönksen PH, Umpleby AM.

J Clin Endocrinol Metab. 2006 Jan;91(1):320-7. Epub 2005 Nov 1.PMID: 16263834 [PubMed - indexed for MEDLINE]Related articlesFree article

GH secretion in acute exercise may result in post-exercise lipolysis.

Wee J, Charlton C, Simpson H, Jackson NC, Shojaee-Moradie F, Stolinski M, Pentecost C, Umpleby AM.

Growth Horm IGF Res. 2005 Dec;15(6):397-404. Epub 2005 Oct 5.PMID: 16213174 [PubMed - indexed for MEDLINE]Related articles

Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy.

Umpleby AM, Das S, Stolinski M, Shojaee-Moradie F, Jackson NC, Jefferson W, Crabtree N, Nightingale P, Shahmanesh M.

Antivir Ther. 2005;10(5):663-70.PMID: 16152760 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp.

Hordern SV, Wright JE, Umpleby AM, Shojaee-Moradie F, Amiss J, Russell-Jones DL.

Diabetologia. 2005 Mar;48(3):420-6. Epub 2005 Feb 24.PMID: 15729576 [PubMed - indexed for MEDLINE]Related articles

Growth hormone and testosterone interact positively to enhance protein and energy metabolism in hypopituitary men.

Gibney J, Wolthers T, Johannsson G, Umpleby AM, Ho KK.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E266-71. Epub 2005 Feb 22.PMID: 15727949 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiretroviral treatment reduces very-low-density lipoprotein and intermediate-density lipoprotein apolipoprotein B fractional catabolic rate in human immunodeficiency virus-infected patients with mild dyslipidemia.

Shahmanesh M, Das S, Stolinski M, Shojaee-Moradie F, Jackson NC, Jefferson W, Cramb R, Nightingale P, Umpleby AM.

J Clin Endocrinol Metab. 2005 Feb;90(2):755-60. Epub 2004 Nov 2.PMID: 15522931 [PubMed - indexed for MEDLINE]Related articlesFree article

Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes.

Saukkonen T, Amin R, Williams RM, Fox C, Yuen KC, White MA, Umpleby AM, Acerini CL, Dunger DB.

J Clin Endocrinol Metab. 2004 Sep;89(9):4634-41.PMID: 15356074 [PubMed - indexed for MEDLINE]Related articlesFree article

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I.

Science. 2004 May 28;304(5675):1325-8.PMID: 15166380 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of growth hormone (GH) replacement therapy on low-density lipoprotein apolipoprotein B100 kinetics in adult patients with GH deficiency: a stable isotope study.

Christ ER, Cummings MH, Jackson N, Stolinski M, Lumb PJ, Wierzbicki AS, Sönksen PH, Russell-Jones DL, Umpleby AM.

J Clin Endocrinol Metab. 2004 Apr;89(4):1801-7.PMID: 15070948 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes.

Alam S, Stolinski M, Pentecost C, Boroujerdi MA, Jones RH, Sonksen PH, Umpleby AM.

J Clin Endocrinol Metab. 2004 Feb;89(2):688-94.PMID: 14764782 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes.

Simpson HL, Jackson NC, Shojaee-Moradie F, Jones RH, Russell-Jones DL, Sönksen PH, Dunger DB, Umpleby AM.

J Clin Endocrinol Metab. 2004 Jan;89(1):425-32.PMID: 14715881 [PubMed - indexed for MEDLINE]Related articlesFree article

High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes.

Healy ML, Gibney J, Russell-Jones DL, Pentecost C, Croos P, Sönksen PH, Umpleby AM.

J Clin Endocrinol Metab. 2003 Nov;88(11):5221-6.PMID: 14602753 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of a specific growth hormone antagonist on overnight insulin requirements and insulin sensitivity in young adults with Type 1 diabetes mellitus.

Williams RM, Amin R, Shojaee-Moradie F, Umpleby AM, Acerini CL, Dunger DB.

Diabetologia. 2003 Sep;46(9):1203-10. Epub 2003 Jul 24.PMID: 12898010 [PubMed - indexed for MEDLINE]Related articles

Combined growth hormone/insulin-like growth factor I in addition to glutamine-supplemented TPN results in net protein anabolism in critical illness.

Carroll PV, Jackson NC, Russell-Jones DL, Treacher DF, Sönksen PH, Umpleby AM.

Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E151-7. Epub 2003 May 20.PMID: 12759221 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of growth hormone (GH) on glycerol and free fatty acid metabolism during exhaustive exercise in GH-deficient adults.

Gibney J, Healy ML, Stolinski M, Bowes SB, Pentecost C, Breen L, McMillan C, Russell-Jones DL, Sonksen PH, Umpleby AM.

J Clin Endocrinol Metab. 2003 Apr;88(4):1792-7.PMID: 12679475 [PubMed - indexed for MEDLINE]Related articlesFree article

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.

Savage DB, Tan GD, Acerini CL, Jebb SA, Agostini M, Gurnell M, Williams RL, Umpleby AM, Thomas EL, Bell JD, Dixon AK, Dunne F, Boiani R, Cinti S, Vidal-Puig A, Karpe F, Chatterjee VK, O'Rahilly S.

Diabetes. 2003 Apr;52(4):910-7.PMID: 12663460 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of hepatic portal glucose sensing in modulating responses to hypoglycaemia in man.

Smith D, Pernet A, Reid H, Bingham E, Rosenthal JM, Macdonald IA, Umpleby AM, Amiel SA.

Diabetologia. 2002 Oct;45(10):1416-24. Epub 2002 Aug 16.PMID: 12378383 [PubMed - indexed for MEDLINE]Related articles

Effect of IGF-I therapy on VLDL apolipoprotein B100 metabolism in type 1 diabetes mellitus.

Christ ER, Carroll PV, Albany E, Umpleby AM, Lumb PJ, Wierzbicki AS, Sönksen PH, Russell-Jones DL.

Am J Physiol Endocrinol Metab. 2002 May;282(5):E1154-62.PMID: 11934682 [PubMed - indexed for MEDLINE]Related articlesFree article

Partitioning glucose distribution/transport, disposal, and endogenous production during IVGTT.

Hovorka R, Shojaee-Moradie F, Carroll PV, Chassin LJ, Gowrie IJ, Jackson NC, Tudor RS, Umpleby AM, Jones RH.

Am J Physiol Endocrinol Metab. 2002 May;282(5):E992-1007.PMID: 11934663 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus.

Christ ER, Carroll PV, Albany E, Umpleby AM, Lumb PJ, Wierzbicki AS, Simpson HL, Sönksen PH, Russell-Ones DL.

Clin Endocrinol (Oxf). 2001 Dec;55(6):777-87.PMID: 11895220 [PubMed - indexed for MEDLINE]Related articles

Glutamine supplementation and GH/IGF-I treatment in critically ill patients: effects on glutamine metabolism and protein balance.

Umpleby AM, Carroll PV, Russell-Jones DL, Treacher DF, Jackson NC.

Nutrition. 2002 Feb;18(2):127-9. No abstract available. PMID: 11844642 [PubMed - indexed for MEDLINE]Related articles

Temporal changes in insulin sensitivity following the development of acute liver failure secondary to acetaminophen.

Clark SJ, Shojaee-Moradie F, Croos P, Seed PT, Umpleby AM, Wendon JA, Miell J.

Hepatology. 2001 Jul;34(1):109-15.PMID: 11431740 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-I and diabetes. A review.

Simpson HL, Umpleby AM, Russell-Jones DL.

Growth Horm IGF Res. 1998 Apr;8(2):83-95. Review.PMID: 10987675 [PubMed - indexed for MEDLINE]Related articles

IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp.

Carroll PV, Christ ER, Umpleby AM, Gowrie I, Jackson N, Bowes SB, Hovorka R, Croos P, Sönksen PH, Russell-Jones DL.

Diabetes. 2000 May;49(5):789-96.PMID: 10905488 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of glutamine supplementation, GH, and IGF-I on glutamine metabolism in critically ill patients.

Jackson NC, Carroll PV, Russell-Jones DL, Sönksen PH, Treacher DF, Umpleby AM.

Am J Physiol Endocrinol Metab. 2000 Feb;278(2):E226-33.PMID: 10662706 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamics of lipoprotein metabolism in adult growth hormone deficiency.

Christ ER, Wierzbicki AS, Cummings MH, Umpleby AM, Russell-Jones DL.

J Endocrinol Invest. 1999;22(5 Suppl):16-21. Review.PMID: 10442565 [PubMed - indexed for MEDLINE]Related articles

Estimating protein turnover with a [15N,13C]leucine tracer: a study using simulated data.

Gowrie IJ, Roudsari AV, Umpleby AM, Hovorka R.

J Theor Biol. 1999 May 21;198(2):165-72.PMID: 10339391 [PubMed - indexed for MEDLINE]Related articles

A surrogate measure of whole body leucine transport across the cell membrane.

Hovorka R, Carroll PV, Gowrie IJ, Jackson NC, Russell-Jones DL, Umpleby AM.

Am J Physiol. 1999 Mar;276(3 Pt 1):E573-9.PMID: 10070026 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of growth hormone (GH) replacement therapy on very low density lipoprotein apolipoprotein B100 kinetics in patients with adult GH deficiency: a stable isotope study.

Christ ER, Cummings MH, Albany E, Umpleby AM, Lumb PJ, Wierzbicki AS, Naoumova RP, Boroujerdi MA, Sönksen PH, Russell-Jones DL.

J Clin Endocrinol Metab. 1999 Jan;84(1):307-16.PMID: 9920100 [PubMed - indexed for MEDLINE]Related articlesFree article

The metabolic consequences of critical illness: acute effects on glutamine and protein metabolism.

Jackson NC, Carroll PV, Russell-Jones DL, Sönksen PH, Treacher DF, Umpleby AM.

Am J Physiol. 1999 Jan;276(1 Pt 1):E163-70.PMID: 9886963 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of low-dose recombinant human insulin-like growth factor-I on insulin sensitivity, growth hormone and glucagon levels in young adults with insulin-dependent diabetes mellitus.

Acerini CL, Harris DA, Matyka KA, Watts AP, Umpleby AM, Russell-Jones DL, Dunger DB.

Metabolism. 1998 Dec;47(12):1481-9.PMID: 9867078 [PubMed - indexed for MEDLINE]Related articles