PubMed

Impaired function of coronary BK(Ca) channels in metabolic syndrome.

Borbouse L, Dick GM, Asano S, Bender SB, Dincer UD, Payne GA, Neeb ZP, Bratz IN, Sturek M, Tune JD.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1629-37. Epub 2009 Sep 11.PMID: 19749164 [PubMed - indexed for MEDLINE]Related articles

Periadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthase.

Payne GA, Bohlen HG, Dincer UD, Borbouse L, Tune JD.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H460-5. Epub 2009 May 29.PMID: 19482966 [PubMed - indexed for MEDLINE]Related articles

Altered mechanism of adenosine-induced coronary arteriolar dilation in early-stage metabolic syndrome.

Bender SB, Tune JD, Borbouse L, Long X, Sturek M, Laughlin MH.

Exp Biol Med (Maywood). 2009 Jun;234(6):683-92. Epub 2009 Mar 23.PMID: 19307464 [PubMed - indexed for MEDLINE]Related articles

Adaptations in the balance between coronary blood flow and myocardial metabolism in endurance athletes.

Tune JD.

J Physiol. 2008 Nov 1;586(Pt 21):5043. No abstract available. PMID: 18978161 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin and mechanisms of endothelial dysfunction and cardiovascular disease.

Knudson JD, Payne GA, Borbouse L, Tune JD.

Curr Hypertens Rep. 2008 Dec;10(6):434-9. Review.PMID: 18959828 [PubMed - indexed for MEDLINE]Related articles

EFFECTS OF LEPTIN ON CARDIOVASCULAR PHYSIOLOGY.

Tune JD, Considine RV.

J Am Soc Hypertens. 2007 Aug;1(4):231-241. No abstract available. PMID: 18670590 [PubMed]Related articlesFree article

Endogenous adipose-derived factors diminish coronary endothelial function via inhibition of nitric oxide synthase.

Payne GA, Borbouse L, Bratz IN, Roell WC, Bohlen HG, Dick GM, Tune JD.

Microcirculation. 2008 Jul;15(5):417-26.PMID: 18574744 [PubMed - indexed for MEDLINE]Related articles

Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome.

Bratz IN, Dick GM, Tune JD, Edwards JM, Neeb ZP, Dincer UD, Sturek M.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2489-96. Epub 2008 Apr 4.PMID: 18390821 [PubMed - indexed for MEDLINE]Related articlesFree article

Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.

Dick GM, Bratz IN, Borbouse L, Payne GA, Dincer UD, Knudson JD, Rogers PA, Tune JD.

Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2371-81. Epub 2008 Mar 28.PMID: 18375717 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of coronary blood flow during hypoxemia.

Tune JD.

Adv Exp Med Biol. 2007;618:25-39. Review.PMID: 18269186 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-induced vasodilation in the right coronary circulation of conscious dogs: role of adrenergic activation.

Setty S, Zong P, Sun W, Tune JD, Downey HF.

Auton Neurosci. 2008 Feb 29;138(1-2):76-82. Epub 2007 Dec 4.PMID: 18055275 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of coronary dysfunction in obesity and insulin resistance.

Knudson JD, Dincer UD, Bratz IN, Sturek M, Dick GM, Tune JD.

Microcirculation. 2007 Jun-Jul;14(4-5):317-38. Review.PMID: 17613805 [PubMed - indexed for MEDLINE]Related articles

Adipokines and coronary vasomotor dysfunction.

Knudson JD, Dick GM, Tune JD.

Exp Biol Med (Maywood). 2007 Jun;232(6):727-36. Review.PMID: 17526764 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow.

Saitoh S, Zhang C, Tune JD, Potter B, Kiyooka T, Rogers PA, Knudson JD, Dick GM, Swafford A, Chilian WM.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2614-21. Epub 2006 Oct 5.PMID: 17023676 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensitization of coronary alpha-adrenoceptor vasoconstriction in the prediabetic metabolic syndrome.

Dincer UD, Araiza AG, Knudson JD, Molina PE, Tune JD.

Microcirculation. 2006 Oct-Nov;13(7):587-95.PMID: 16990217 [PubMed - indexed for MEDLINE]Related articles

Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation.

Dick GM, Katz PS, Farias M 3rd, Morris M, James J, Knudson JD, Tune JD.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2997-3002. Epub 2006 Aug 11.PMID: 16905596 [PubMed - indexed for MEDLINE]Related articlesFree article

Withdrawal of vasoconstrictor influences in local metabolic coronary vasodilation.

Tune JD.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2044-6. Epub 2006 Jul 14. No abstract available. PMID: 16844914 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysfunction of cardiac ryanodine receptors in the metabolic syndrome.

Dincer UD, Araiza A, Knudson JD, Shao CH, Bidasee KR, Tune JD.

J Mol Cell Cardiol. 2006 Jul;41(1):108-14. Epub 2006 Jun 21.PMID: 16793060 [PubMed - indexed for MEDLINE]Related articles

H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels.

Rogers PA, Dick GM, Knudson JD, Focardi M, Bratz IN, Swafford AN Jr, Saitoh S, Tune JD, Chilian WM.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2473-82. Epub 2006 Jun 2.PMID: 16751285 [PubMed - indexed for MEDLINE]Related articlesFree article

Coronary vasomotor reactivity to endothelin-1 in the prediabetic metabolic syndrome.

Knudson JD, Rogers PA, Dincer UD, Bratz IN, Araiza AG, Dick GM, Tune JD.

Microcirculation. 2006 Apr-May;13(3):209-18.PMID: 16627363 [PubMed - indexed for MEDLINE]Related articles

Increased lymphatic flow in the thoracic duct during manipulative intervention.

Knott EM, Tune JD, Stoll ST, Downey HF.

J Am Osteopath Assoc. 2005 Oct;105(10):447-56.PMID: 16314677 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of oxygen demand/supply balance in the right ventricle.

Zong P, Tune JD, Downey HF.

Exp Biol Med (Maywood). 2005 Sep;230(8):507-19. Review.PMID: 16118400 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin resistance extends to the coronary vasculature in prediabetic dogs and provides a protective adaptation against endothelial dysfunction.

Knudson JD, Dincer UD, Dick GM, Shibata H, Akahane R, Saito M, Tune JD.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1038-46. Epub 2005 May 13.PMID: 15894577 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction.

Knudson JD, Dincer UD, Zhang C, Swafford AN Jr, Koshida R, Picchi A, Focardi M, Dick GM, Tune JD.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H48-56. Epub 2005 Mar 4.PMID: 15749744 [PubMed - indexed for MEDLINE]Related articlesFree article

Coronary arteriolar vasoconstriction to angiotensin II is augmented in prediabetic metabolic syndrome via activation of AT1 receptors.

Zhang C, Knudson JD, Setty S, Araiza A, Dincer UD, Kuo L, Tune JD.

Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2154-62. Epub 2005 Jan 14.PMID: 15653764 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of endothelin in alpha-adrenoceptor coronary vasoconstriction.

Gorman MW, Farias M 3rd, Richmond KN, Tune JD, Feigl EO.

Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1937-42. Epub 2004 Dec 9.PMID: 15591092 [PubMed - indexed for MEDLINE]Related articlesFree article

C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations.

Swafford AN Jr, Bratz IN, Knudson JD, Rogers PA, Timmerman JM, Tune JD, Dick GM.

Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1786-95. Epub 2004 Nov 24.PMID: 15563529 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide contributes to oxygen demand-supply balance in hypoperfused right ventricle.

Setty S, Tune JD, Downey HF.

Cardiovasc Res. 2004 Dec 1;64(3):431-6.PMID: 15537496 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide contributes to right coronary vasodilation during systemic hypoxia.

Martinez RR, Setty S, Zong P, Tune JD, Downey HF.

Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1139-46. Epub 2004 Oct 28.PMID: 15513958 [PubMed - indexed for MEDLINE]Related articlesFree article

Intermittent hypoxic training protects canine myocardium from infarction.

Zong P, Setty S, Sun W, Martinez R, Tune JD, Ehrenburg IV, Tkatchouk EN, Mallet RT, Downey HF.

Exp Biol Med (Maywood). 2004 Sep;229(8):806-12.PMID: 15337835 [PubMed - indexed for MEDLINE]Related articlesFree article

Matching coronary blood flow to myocardial oxygen consumption.

Tune JD, Gorman MW, Feigl EO.

J Appl Physiol. 2004 Jul;97(1):404-15. Review.PMID: 15220323 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha-adrenergic vasoconstrictor tone limits right coronary blood flow in exercising dogs.

Zong P, Sun W, Setty S, Tune JD, Downey HF.

Exp Biol Med (Maywood). 2004 Apr;229(4):312-22.PMID: 15044714 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha-adrenoceptor-mediated coronary vasoconstriction is augmented during exercise in experimental diabetes mellitus.

Setty S, Sun W, Martinez R, Downey HF, Tune JD.

J Appl Physiol. 2004 Jul;97(1):431-8. Epub 2004 Feb 20.PMID: 14978008 [PubMed - indexed for MEDLINE]Related articlesFree article

Coronary blood flow regulation in the prediabetic metabolic syndrome.

Setty S, Sun W, Tune JD.

Basic Res Cardiol. 2003 Nov;98(6):416-23. Epub 2003 May 16.PMID: 14556087 [PubMed - indexed for MEDLINE]Related articles

Endogenous nitric oxide regulates right coronary blood flow during acute pulmonary hypertension in conscious dogs.

Zong P, Tune JD, Setty S, Downey HF.

Basic Res Cardiol. 2002 Sep;97(5):392-8.PMID: 12200639 [PubMed - indexed for MEDLINE]Related articles

Coronary blood flow control is impaired at rest and during exercise in conscious diabetic dogs.

Tune JD, Yeh C, Setty S, Zong P, Downey HF.

Basic Res Cardiol. 2002 May;97(3):248-57.PMID: 12061395 [PubMed - indexed for MEDLINE]Related articles

ATP-dependent K(+) channels contribute to local metabolic coronary vasodilation in experimental diabetes.

Tune JD, Yeh C, Setty S, Downey HF.

Diabetes. 2002 Apr;51(4):1201-7.PMID: 11916945 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of coronary blood flow during exercise.

Tune JD, Richmond KN, Gorman MW, Feigl EO.

Exp Biol Med (Maywood). 2002 Apr;227(4):238-50. Review.PMID: 11910046 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide modulates right ventricular flow and oxygen consumption during norepinephrine infusion.

Setty S, Tune JD, Downey HF.

Am J Physiol Heart Circ Physiol. 2002 Feb;282(2):H696-703.PMID: 11788420 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous nitric oxide modulates myocardial oxygen consumption in canine right ventricle.

Setty S, Bian X, Tune JD, Downey HF.

Am J Physiol Heart Circ Physiol. 2001 Aug;281(2):H831-7.PMID: 11454588 [PubMed - indexed for MEDLINE]Related articlesFree article

K(ATP)(+) channels, nitric oxide, and adenosine are not required for local metabolic coronary vasodilation.

Tune JD, Richmond KN, Gorman MW, Feigl EO.

Am J Physiol Heart Circ Physiol. 2001 Feb;280(2):H868-75.PMID: 11158988 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative analysis of feedforward sympathetic coronary vasodilation in exercising dogs.

Gorman MW, Tune JD, Richmond KN, Feigl EO.

J Appl Physiol. 2000 Nov;89(5):1903-11.PMID: 11053342 [PubMed - indexed for MEDLINE]Related articlesFree article

Feedforward sympathetic coronary vasodilation in exercising dogs.

Gorman MW, Tune JD, Richmond KN, Feigl EO.

J Appl Physiol. 2000 Nov;89(5):1892-902.PMID: 11053341 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of K(ATP)(+) channels and adenosine in the control of coronary blood flow during exercise.

Richmond KN, Tune JD, Gorman MW, Feigl EO.

J Appl Physiol. 2000 Aug;89(2):529-36.PMID: 10926635 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of nitric oxide and adenosine in control of coronary blood flow in exercising dogs.

Tune JD, Richmond KN, Gorman MW, Feigl EO.

Circulation. 2000 Jun 27;101(25):2942-8.PMID: 10869267 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise.

Tune JD, Richmond KN, Gorman MW, Olsson RA, Feigl EO.

Am J Physiol Heart Circ Physiol. 2000 Jan;278(1):H74-84.PMID: 10644586 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of K+ATP channels in local metabolic coronary vasodilation.

Richmond KN, Tune JD, Gorman MW, Feigl EO.

Am J Physiol. 1999 Dec;277(6 Pt 2):H2115-23.PMID: 10600828 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin improves cardiac contractile function and oxygen utilization efficiency during moderate ischemia without compromising myocardial energetics.

Tune JD, Mallet RT, Downey HF.

J Mol Cell Cardiol. 1998 Oct;30(10):2025-35.PMID: 9799656 [PubMed - indexed for MEDLINE]Related articles

Insulin improves contractile function during moderate ischemia in canine left ventricle.

Tune JD, Mallet RT, Downey HF.

Am J Physiol. 1998 May;274(5 Pt 2):H1574-81.PMID: 9612366 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated right atrial pressure does not reduce collateral blood flow to ischemic myocardium.

Yu Y, Tune JD, Downey HF.

Am J Physiol. 1997 Nov;273(5 Pt 2):H2296-303.PMID: 9374766 [PubMed - indexed for MEDLINE]Related articlesFree article