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    Results: 23

    1.

    Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis.

    Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E.

    Biochem Biophys Res Commun. 2009 Feb 20;379(4):806-11. Epub 2008 Dec 16.PMID: 19094966 [PubMed - indexed for MEDLINE]Related articles

    2.

    Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues.

    Kojima K, Motoshima H, Tsutsumi A, Igata M, Matsumura T, Kondo T, Kawashima J, Ichinose K, Furukawa N, Inukai K, Katayama S, Goldstein BJ, Nishikawa T, Tsuruzoe K, Araki E.

    Biochem Biophys Res Commun. 2008 Nov 14;376(2):434-8. Epub 2008 Sep 19.PMID: 18789895 [PubMed - indexed for MEDLINE]Related articles

    3.

    Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.

    Taketa K, Matsumura T, Yano M, Ishii N, Senokuchi T, Motoshima H, Murata Y, Kim-Mitsuyama S, Kawada T, Itabe H, Takeya M, Nishikawa T, Tsuruzoe K, Araki E.

    J Biol Chem. 2008 Apr 11;283(15):9852-62. Epub 2008 Jan 21.PMID: 18208815 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice.

    Goto H, Nishikawa T, Sonoda K, Kondo T, Kukidome D, Fujisawa K, Yamashiro T, Motoshima H, Matsumura T, Tsuruzoe K, Araki E.

    Biochem Biophys Res Commun. 2008 Feb 15;366(3):814-20. Epub 2007 Dec 18.PMID: 18083119 [PubMed - indexed for MEDLINE]Related articles

    5.

    IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance.

    Murata Y, Tsuruzoe K, Kawashima J, Furukawa N, Kondo T, Motoshima H, Igata M, Taketa K, Sasaki K, Kishikawa H, Kahn CR, Toyonaga T, Araki E.

    Biochem Biophys Res Commun. 2007 Dec 14;364(2):301-7. Epub 2007 Oct 12.PMID: 17950694 [PubMed - indexed for MEDLINE]Related articles

    6.

    [Resistin and TNFalpha]

    Araki E, Tsuruzoe K, Murata Y.

    Nippon Rinsho. 2006 Dec 28;64 Suppl 9:225-30. Review. Japanese. No abstract available. PMID: 17458222 [PubMed - indexed for MEDLINE]Related articles

    7.

    [Type A or type B syndrome of insulin resistance]

    Araki E, Tsuruzoe K.

    Nippon Rinsho. 2006 Sep 28;Suppl 3:64-8. Review. Japanese. No abstract available. PMID: 17022501 [PubMed - indexed for MEDLINE]Related articles

    8.

    Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling.

    Imoto K, Kukidome D, Nishikawa T, Matsuhisa T, Sonoda K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Tsuruzoe K, Matsumura T, Ichijo H, Araki E.

    Diabetes. 2006 May;55(5):1197-204.PMID: 16644673 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A case of slowly progressive type 1 diabetes with unstable glycemic control caused by unusual insulin antibody and successfully treated with steroid therapy.

    Matsuyoshi A, Shimoda S, Tsuruzoe K, Taketa K, Chirioka T, Sakamoto F, Sakakida M, Miyamura N, Araki E.

    Diabetes Res Clin Pract. 2006 Jun;72(3):238-43. Epub 2006 Jan 24.PMID: 16439034 [PubMed - indexed for MEDLINE]Related articles

    10.

    Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.

    Igata M, Motoshima H, Tsuruzoe K, Kojima K, Matsumura T, Kondo T, Taguchi T, Nakamaru K, Yano M, Kukidome D, Matsumoto K, Toyonaga T, Asano T, Nishikawa T, Araki E.

    Circ Res. 2005 Oct 14;97(8):837-44. Epub 2005 Sep 8.PMID: 16151020 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    [Polymorphisms of PPARs and metabolic disorders]

    Araki E, Igata M, Motoshima H, Tsuruzoe K.

    Nippon Rinsho. 2005 Apr;63(4):617-22. Review. Japanese. PMID: 15828229 [PubMed - indexed for MEDLINE]Related articles

    12.

    AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.

    Nakamaru K, Matsumoto K, Taguchi T, Suefuji M, Murata Y, Igata M, Kawashima J, Kondo T, Motoshima H, Tsuruzoe K, Miyamura N, Toyonaga T, Araki E.

    Biochem Biophys Res Commun. 2005 Mar 11;328(2):449-54.PMID: 15694368 [PubMed - indexed for MEDLINE]Related articles

    13.

    Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.

    Kodama S, Toyonaga T, Kondo T, Matsumoto K, Tsuruzoe K, Kawashima J, Goto H, Kume K, Kume S, Sakakida M, Araki E.

    Biochem Biophys Res Commun. 2005 Feb 25;327(4):1170-8.PMID: 15652518 [PubMed - indexed for MEDLINE]Related articles

    14.

    Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway.

    Hirashima Y, Tsuruzoe K, Kodama S, Igata M, Toyonaga T, Ueki K, Kahn CR, Araki E.

    J Endocrinol. 2003 Nov;179(2):253-66.PMID: 14596677 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin down-regulates resistin mRNA through the synthesis of protein(s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes.

    Kawashima J, Tsuruzoe K, Motoshima H, Shirakami A, Sakai K, Hirashima Y, Toyonaga T, Araki E.

    Diabetologia. 2003 Feb;46(2):231-40. Epub 2003 Feb 11.PMID: 12627322 [PubMed - indexed for MEDLINE]Related articles

    16.

    [Polymorphisms in insulin receptor substrate-1 (IRS-1) gene]

    Araki E, Tsuruzoe K.

    Nippon Rinsho. 2002 Jul;60 Suppl 7:559-64. Review. Japanese. No abstract available. PMID: 12238098 [PubMed - indexed for MEDLINE]Related articles

    17.

    Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: a possible model for the development of type 2 diabetes.

    Shirakami A, Toyonaga T, Tsuruzoe K, Shirotani T, Matsumoto K, Yoshizato K, Kawashima J, Hirashima Y, Miyamura N, Kahn CR, Araki E.

    J Endocrinol. 2002 Aug;174(2):309-19.PMID: 12176670 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling.

    Tsuruzoe K, Emkey R, Kriauciunas KM, Ueki K, Kahn CR.

    Mol Cell Biol. 2001 Jan;21(1):26-38.PMID: 11113178 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Possible involvement of atypical protein kinase C (PKC) in glucose-sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive but phorbol 12-myristate 13-acetate (PMA) and Gö 6976-insensitive pathway.

    Furukawa N, Shirotani T, Araki E, Kaneko K, Todaka M, Matsumoto K, Tsuruzoe K, Motoshima H, Yoshizato K, Kishikawa H, Shichiri M.

    Endocr J. 1999 Feb;46(1):43-58.PMID: 10426567 [PubMed - indexed for MEDLINE]Related articles

    20.

    Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.

    Tsuruzoe K, Araki E, Furukawa N, Shirotani T, Matsumoto K, Kaneko K, Motoshima H, Yoshizato K, Shirakami A, Kishikawa H, Miyazaki J, Shichiri M.

    Diabetes. 1998 Apr;47(4):621-31.PMID: 9568696 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling.

    Yoshimura R, Araki E, Ura S, Todaka M, Tsuruzoe K, Furukawa N, Motoshima H, Yoshizato K, Kaneko K, Matsuda K, Kishikawa H, Shichiri M.

    Diabetes. 1997 Jun;46(6):929-36.PMID: 9166661 [PubMed - indexed for MEDLINE]Related articles

    22.

    Cell-specific regulation of IRS-1 gene expression: role of E box and C/EBP binding site in HepG2 cells and CHO cells.

    Matsuda K, Araki E, Yoshimura R, Tsuruzoe K, Furukawa N, Kaneko K, Motoshima H, Yoshizato K, Kishikawa H, Shichiri M.

    Diabetes. 1997 Mar;46(3):354-62.PMID: 9032089 [PubMed - indexed for MEDLINE]Related articles

    23.

    A carboxy-terminal truncation of human alpha-galactosidase A in a heterozygous female with Fabry disease and modification of the enzymatic activity by the carboxy-terminal domain. Increased, reduced, or absent enzyme activity depending on number of amino acid residues deleted.

    Miyamura N, Araki E, Matsuda K, Yoshimura R, Furukawa N, Tsuruzoe K, Shirotani T, Kishikawa H, Yamaguchi K, Shichiri M.

    J Clin Invest. 1996 Oct 15;98(8):1809-17.PMID: 8878432 [PubMed - indexed for MEDLINE]Related articlesFree article

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