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Albiglutide, an albumin-based fusion of glucagon-like peptide 1 for the potential treatment of type 2 diabetes.
Tomkin GH.
Curr Opin Mol Ther. 2009 Oct;11(5):579-88.PMID: 19806507 [PubMed - in process]Related articles
Ezetimibe - new anti-atherogenic properties?
Br J Pharmacol. 2009 Apr;156(8):1216-7.PMID: 19751315 [PubMed - in process]Related articles
The effect of antidiabetic drugs on genes regulating lipid metabolism.
Curr Opin Lipidol. 2009 Feb;20(1):10-6. Review.PMID: 19106706 [PubMed - indexed for MEDLINE]Related articles
The intestine as a regulator of cholesterol homeostasis in diabetes.
Atheroscler Suppl. 2008 Sep;9(2):27-32. Epub 2008 Aug 6. Review.PMID: 18693145 [PubMed - indexed for MEDLINE]Related articles
Targets for intervention in dyslipidemia in diabetes.
Diabetes Care. 2008 Feb;31 Suppl 2:S241-8. Review.PMID: 18227492 [PubMed - indexed for MEDLINE]Related articlesFree article
Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: the relationship between the liver and intestine in control and streptozotosin diabetic rats.
Lally S, Owens D, Tomkin GH.
Metabolism. 2007 Mar;56(3):430-8.PMID: 17292734 [PubMed - indexed for MEDLINE]Related articles
The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes.
Atherosclerosis. 2007 Aug;193(2):343-51. Epub 2006 Nov 15.PMID: 17109865 [PubMed - indexed for MEDLINE]Related articles
Sitosterol and cholesterol in chylomicrons of type 2 diabetic and non-diabetic subjects: the relationship with ATP binding cassette proteins G5 and G8 and Niemann-Pick C1-like 1 mRNA.
Lally SE, Owens D, Tomkin GH.
Diabetologia. 2007 Jan;50(1):217-9. Epub 2006 Nov 11. No abstract available. PMID: 17102949 [PubMed - indexed for MEDLINE]Related articles
Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein.
Lally S, Tan CY, Owens D, Tomkin GH.
Diabetologia. 2006 May;49(5):1008-16. Epub 2006 Mar 4.PMID: 16518588 [PubMed - indexed for MEDLINE]Related articles
Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition.
Phillips C, Mullan K, Owens D, Tomkin GH.
Atherosclerosis. 2006 Jul;187(1):57-64. Epub 2005 Sep 23.PMID: 16183064 [PubMed - indexed for MEDLINE]Related articles
Low density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes.
Phillips C, Owens D, Collins P, Tomkin GH.
Atherosclerosis. 2005 Jul;181(1):109-14.PMID: 15939061 [PubMed - indexed for MEDLINE]Related articles
Comparison of diets high in monounsaturated versus polyunsaturated fatty acid on postprandial lipoproteins in diabetes.
Madigan C, Ryan M, Owens D, Collins P, Tomkin GH.
Ir J Med Sci. 2005 Jan-Mar;174(1):8-20.PMID: 15868884 [PubMed - indexed for MEDLINE]Related articles
Hyperglycaemia: the relation to dyslipidaemia and atherosclerosis.
Ir J Med Sci. 2002 Jul-Sep;171(3):161-4. Review. No abstract available. PMID: 15736358 [PubMed - indexed for MEDLINE]Related articles
A delayed diagnosis of stiff person syndrome.
Yeow TP, Tomkin GH.
Hosp Med. 2004 Mar;65(3):178-9. No abstract available. PMID: 15052911 [PubMed - indexed for MEDLINE]Related articles
Microsomal triglyceride transfer protein polymorphisms and lipoprotein levels in type 2 diabetes.
QJM. 2004 Apr;97(4):211-8.PMID: 15028851 [PubMed - indexed for MEDLINE]Related articlesFree article
Conway Memorial Lecture 2002. The dyslipidaemia of diabetes: lessons in the pathogenesis of atherosclerosis.
Ir J Med Sci. 2002 Oct-Dec;171(4):220-4. No abstract available. PMID: 12647914 [PubMed - indexed for MEDLINE]Related articles
Defective chylomicron synthesis as a cause of delayed particle clearance in diabetes?
Phillips C, Madigan C, Owens D, Collins P, Tomkin GH.
Int J Exp Diabetes Res. 2002 Jul-Sep;3(3):171-8.PMID: 12458658 [PubMed - indexed for MEDLINE]Related articlesFree article
Robert Graves Memorial Lecture. Diabetes and atherosclerosis--a gut review.
Ir J Med Sci. 2002 Apr-Jun;171(2):105-9. No abstract available. PMID: 12173881 [PubMed - indexed for MEDLINE]Related articles
Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidemia in diabetes.
Phillips C, Bennett A, Anderton K, Owens D, Collins P, White D, Tomkin GH.
Metabolism. 2002 Jul;51(7):847-52.PMID: 12077729 [PubMed - indexed for MEDLINE]Related articles
Microsomal triglyceride transfer protein: does insulin resistance play a role in the regulation of chylomicron assembly?
Atherosclerosis. 2002 Feb;160(2):355-60.PMID: 11849658 [PubMed - indexed for MEDLINE]Related articles
The relationship between cholesterol absorption and intestinal cholesterol synthesis in the diabetic rat model.
Gleeson A, Owens D, Collins P, Johnson A, Tomkin GH.
Int J Exp Diabetes Res. 2000;1(3):203-10.PMID: 11467411 [PubMed - indexed for MEDLINE]Related articlesFree article
Diabetic vascular disease and the rising star of protein kinase C.
Diabetologia. 2001 Jun;44(6):657-8. No abstract available. PMID: 11440358 [PubMed - indexed for MEDLINE]Related articles
Abnormalities in apo B-containing lipoproteins in diabetes and atherosclerosis.
Tomkin GH, Owens D.
Diabetes Metab Res Rev. 2001 Jan-Feb;17(1):27-43. Review.PMID: 11241889 [PubMed - indexed for MEDLINE]Related articles
Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet.
Diabetes Care. 2000 Oct;23(10):1472-7.PMID: 11023139 [PubMed - indexed for MEDLINE]Related articlesFree article
Postprandial apolipoprotein B48-and B100-containing lipoproteins in type 2 diabetes: do statins have a specific effect on triglyceride metabolism?
Battula SB, Fitzsimons O, Moreno S, Owens D, Collins P, Johnson A, Tomkin GH.
Metabolism. 2000 Aug;49(8):1049-54.PMID: 10954025 [PubMed - indexed for MEDLINE]Related articles
Lipoproteins and low-dose estradiol replacement therapy in post-menopausal Type 2 diabetic patients: the effect of addition of norethisterone acetate.
Owens D, Collins PB, Johnson A, Tomkin GH.
Diabet Med. 2000 Apr;17(4):308-15.PMID: 10821298 [PubMed - indexed for MEDLINE]Related articles
Diabetes and the Mediterranean diet: a beneficial effect of oleic acid on insulin sensitivity, adipocyte glucose transport and endothelium-dependent vasoreactivity.
Ryan M, McInerney D, Owens D, Collins P, Johnson A, Tomkin GH.
QJM. 2000 Feb;93(2):85-91.PMID: 10700478 [PubMed - indexed for MEDLINE]Related articlesFree article
Improved metabolic control reduces the number of postprandial apolipoprotein B-48-containing particles in type 2 diabetes.
Phillips C, Murugasu G, Owens D, Collins P, Johnson A, Tomkin GH.
Atherosclerosis. 2000 Feb;148(2):283-91.PMID: 10657563 [PubMed - indexed for MEDLINE]Related articles
The role of microsomal triglyceride transfer protein and dietary cholesterol in chylomicron production in diabetes.
Gleeson A, Anderton K, Owens D, Bennett A, Collins P, Johnson A, White D, Tomkin GH.
Diabetologia. 1999 Aug;42(8):944-8.PMID: 10491754 [PubMed - indexed for MEDLINE]Related articles
The fatty acid distribution in low density lipoprotein in diabetes.
Prescott J, Owens D, Collins P, Johnson A, Tomkin GH.
Biochim Biophys Acta. 1999 Jul 9;1439(1):110-6.PMID: 10395970 [PubMed - indexed for MEDLINE]Related articles
Association between low-density lipoprotein composition and its metabolism in non-insulin-dependent diabetes mellitus.
Deegan P, Owens D, Collins P, Johnson A, Tomkin GH.
Metabolism. 1999 Jan;48(1):118-24.PMID: 9920155 [PubMed - indexed for MEDLINE]Related articles
Antibodies to oxidized lipoproteins and their relationship to myocardial infarction.
Ryan M, Owens D, Kilbride B, Collins P, Johnson A, Tomkin GH.
QJM. 1998 Jun;91(6):411-5.PMID: 9709459 [PubMed - indexed for MEDLINE]Related articlesFree article
Cellular cholesterol synthesis--the relationship to post-prandial glucose and insulin following weight loss.
Griffin M, Frazer A, Johnson A, Collins P, Owens D, Tomkin GH.
Atherosclerosis. 1998 Jun;138(2):313-8.PMID: 9690914 [PubMed - indexed for MEDLINE]Related articles
Acute hypertriglyceridaemic pancreatitis in a pregnant Indian: a new lipoprotein lipase gene mutation.
Murugasu CG, Armstrong G, Creedon G, Cavanna JS, Galton DJ, Tomkin GH.
J R Soc Med. 1998 Apr;91(4):205-7. No abstract available. PMID: 9659309 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of dietary cholesterol in the regulation of postprandial apolipoprotein B48 levels in diabetes.
Taggart C, Gibney J, Owens D, Collins P, Johnson A, Tomkin GH.
Diabet Med. 1997 Dec;14(12):1051-8.PMID: 9455933 [PubMed - indexed for MEDLINE]Related articles
Autoantibodies to oxidized low density lipoprotein: the relationship to low density lipoprotein fatty acid composition in diabetes.
Griffin ME, McInerney D, Fraser A, Johnson AH, Collins PB, Owens D, Tomkin GH.
Diabet Med. 1997 Sep;14(9):741-7.PMID: 9300223 [PubMed - indexed for MEDLINE]Related articles
Elevated triglyceride-rich lipoproteins in diabetes. A study of apolipoprotein B-48.
Curtin A, Deegan P, Owens D, Collins P, Johnson A, Tomkin GH.
Acta Diabetol. 1996 Sep;33(3):205-10.PMID: 8904926 [PubMed - indexed for MEDLINE]Related articles
Lipoprotein composition in NIDDM: effects of dietary oleic acid on the composition, oxidisability and function of low and high density lipoproteins.
Dimitriadis E, Griffin M, Collins P, Johnson A, Owens D, Tomkin GH.
Diabetologia. 1996 Jun;39(6):667-76.PMID: 8781762 [PubMed - indexed for MEDLINE]Related articles
Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function.
Griffin ME, Dimitriadis E, Lenehan K, Owens D, Collins P, Johnson A, Tomkin GH.
QJM. 1996 Mar;89(3):211-6.PMID: 8731565 [PubMed - indexed for MEDLINE]Related articlesFree article
Increased esterification of cholesterol and transfer of cholesteryl ester to apo B-containing lipoproteins in Type 2 diabetes: relationship to serum lipoproteins A-I and A-II.
Jones RJ, Owens D, Brennan C, Collins PB, Johnson AH, Tomkin GH.
Atherosclerosis. 1996 Jan 26;119(2):151-7.PMID: 8808492 [PubMed - indexed for MEDLINE]Related articles
Intestinally derived lipoprotein particles in non-insulin-dependent diabetic patients with and without hypertriglyceridaemia.
Acta Diabetol. 1995 Dec;32(4):244-50.PMID: 8750763 [PubMed - indexed for MEDLINE]Related articles
Oxidation of low-density lipoprotein in NIDDM: its relationship to fatty acid composition.
Dimitriadis E, Griffin M, Owens D, Johnson A, Collins P, Tomkin GH.
Diabetologia. 1995 Nov;38(11):1300-6.PMID: 8582539 [PubMed - indexed for MEDLINE]Related articles
The effect of reduction of lipoprotein (a) on cellular cholesterol synthesis in non-diabetic and type 2 diabetic subjects.
Gilligan S, Owens D, Stinson J, Collins P, Johnson A, Tomkin GH.
Biochim Biophys Acta. 1995 Jan 20;1254(2):187-92.PMID: 7827123 [PubMed - indexed for MEDLINE]Related articles
Alterations in apolipoprotein B-48 in the postprandial state in NIDDM.
Diabetologia. 1994 Dec;37(12):1259-64.PMID: 7895956 [PubMed - indexed for MEDLINE]Related articles
Insulin and lipoprotein metabolism with special reference to the diabetic state.
Diabetes Metab Rev. 1994 Oct;10(3):225-52. Review. No abstract available. PMID: 7835171 [PubMed - indexed for MEDLINE]Related articles
Clinical chemistry and coagulation.
Curr Opin Lipidol. 1994 Jun;5(3):U84-7. No abstract available. PMID: 7952907 [PubMed - indexed for MEDLINE]Related articles
Anti-atherogenic action of oestrogen.
Lancet. 1994 Mar 5;343(8897):598. No abstract available. PMID: 7906343 [PubMed - indexed for MEDLINE]Related articles
Effects of low density lipoprotein of varying composition on cholesterol levels in human monocyte-derived macrophages.
McBrinn SP, Johnson AH, Tomkin GH, Collins PB.
Biochem Soc Trans. 1994 Feb;22(1):36S. No abstract available. PMID: 8206258 [PubMed - indexed for MEDLINE]Related articles
Altered regulation of cholesterol metabolism in type I diabetic women during the menstrual cycle.
Owens D, Cox M, Caird J, Gilligan S, Collins P, Johnson A, Tomkin GH.
Diabet Med. 1993 Aug-Sep;10(7):647-53.PMID: 8403827 [PubMed - indexed for MEDLINE]Related articles
Glycosylated low density lipoprotein is more sensitive to oxidation: implications for the diabetic patient?
Bowie A, Owens D, Collins P, Johnson A, Tomkin GH.
Atherosclerosis. 1993 Aug;102(1):63-7.PMID: 8257453 [PubMed - indexed for MEDLINE]Related articles
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Int J Exp Diabetes Res. 2002 Jul-Sep; 3(3):171-8.
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J R Soc Med. 1998 Apr; 91(4):205-7.
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